Amiable, C. and Paoletti, J. and Haouz, A. and Padilla, A. and Labesse, G. and Kaminski, P. A. and Pochet, S.

6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: synthesis, structural studies and cytotoxic activities

Eur J Med Chem (2014)

85, 418-37

10.1016/j.ejmech.2014.07.110

Andre-Miral, C. and Kone, F. M. and Solleux, C. and Grandjean, C. and Dion, M. and Tran, V. and Tellier, C.

De novo design of a trans-beta-N-acetylglucosaminidase activity from a GH1 beta-glycosidase by mechanism engineering

Glycobiology (2015)

25, 394-402

10.1093/glycob/cwu121

Angelone, T. and Caruso, A. and Rochais, C. and Caputo, A. M. and Cerra, M. C. and Dallemagne, P. and Filice, E. and Genest, D. and Pasqua, T. and Puoci, F. and Saturnino, C. and Sinicropi, M. S. and El-Kashef, H.

Indenopyrazole oxime ethers: synthesis and beta1-adrenergic blocking activity

Eur J Med Chem (2015)

92, 672-81

10.1016/j.ejmech.2015.01.037

Antigny, F. and Norez, C. and Becq, F. and Vandebrouck, C.

CFTR and Ca Signaling in Cystic Fibrosis

Front Pharmacol (2011)

2, 67

10.3389/fphar.2011.00067

Aouadi, W. and Blanjoie, A. and Vasseur, J. J. and Debart, F. and Canard, B. and Decroly, E.

Binding of the Methyl Donor S-Adenosyl-l-Methionine to Middle East Respiratory Syndrome Coronavirus 2'-O-Methyltransferase nsp16 Promotes Recruitment of the Allosteric Activator nsp10

J Virol (2017)

91,

10.1128/JVI.02217-16

Aouadi, W. and Eydoux, C. and Coutard, B. and Martin, B. and Debart, F. and Vasseur, J. J. and Contreras, J. M. and Morice, C. and Querat, G. and Jung, M. L. and Canard, B. and Guillemot, J. C. and Decroly, E.

Toward the identification of viral cap-methyltransferase inhibitors by fluorescence screening assay

Antiviral Res (2017)

144, 330-339

10.1016/j.antiviral.2017.06.021

Apel, C. and Geny, C. and Dumontet, V. and Birlirakis, N. and Roussi, F. and Pham, V. C. and Doan Thi Mai, H. and Nguyen, V. H. and Chau, V. M. and Litaudon, M.

Endiandric acid analogues from Beilschmiedia ferruginea as dual inhibitors of Bcl-xL/Bak and Mcl-1/Bid interactions

J Nat Prod (2014)

77, 1430-7

10.1021/np500170v

Araujo, J. R. and Tomas, J. and Brenner, C. and Sansonetti, P. J.

Impact of high-fat diet on the intestinal microbiota and small intestinal physiology before and after the onset of obesity

Biochimie (2017)

141, 97-106

10.1016/j.biochi.2017.05.019

Ardes-Guisot, N. and Alonzi, D. S. and Reinkensmeier, G. and Butters, T. D. and Norez, C. and Becq, F. and Shimada, Y. and Nakagawa, S. and Kato, A. and Bleriot, Y. and Sollogoub, M. and Vauzeilles, B.

Selection of the biological activity of DNJ neoglycoconjugates through click length variation of the side chain

Org Biomol Chem (2011)

9, 5373-88

10.1039/c1ob05119a

Ardhaoui, M. and Bhatt, S. and Zheng, M. and Dowling, D. and Jolivalt, C. and Khonsari, F. A.

Biosensor based on laccase immobilized on plasma polymerized allylamine/carbon electrode

Mater Sci Eng C Mater Biol Appl (2013)

33, 3197-205

10.1016/j.msec.2013.03.052

Ardhaoui, M. and Zheng, M. and Pulpytel, J. and Dowling, D. and Jolivalt, C. and Khonsari, F. A.

Plasma functionalized carbon electrode for laccase-catalyzed oxygen reduction by direct electron transfer

Bioelectrochemistry (2013)

91, 52-61

10.1016/j.bioelechem.2012.12.005

Armando, S. and Quoyer, J. and Lukashova, V. and Maiga, A. and Percherancier, Y. and Heveker, N. and Pin, J. P. and Prezeau, L. and Bouvier, M.

The chemokine CXC4 and CC2 receptors form homo- and heterooligomers that can engage their signaling G-protein effectors and betaarrestin

FASEB J (2014)

28, 4509-23

10.1096/fj.13-242446

Arora, R. and Di Michele, M. and Stes, E. and Vandermarliere, E. and Martens, L. and Gevaert, K. and Van Heerde, E. and Linders, J. T. and Brehmer, D. and Jacoby, E. and Bonnet, P.

Structural investigation of B-Raf paradox breaker and inducer inhibitors

J Med Chem (2015)

58, 1818-31

10.1021/jm501667n

Assad Kahn, S. and Costa, S. L. and Gholamin, S. and Nitta, R. T. and Dubois, L. G. and Feve, M. and Zeniou, M. and Coelho, P. L. and El-Habr, E. and Cadusseau, J. and Varlet, P. and Mitra, S. S. and Devaux, B. and Kilhoffer, M. C. and Cheshier, S. H. and Moura-Neto, V. and Haiech, J. and Junier, M. P. and Chneiweiss, H.

The anti-hypertensive drug prazosin inhibits glioblastoma growth via the PKCdelta-dependent inhibition of the AKT pathway

EMBO Mol Med (2016)

8, 511-26

10.15252/emmm.201505421

Atif, M. L. and Brenet, A. and Hageaux, S. and Fave, M. H. and Cochet, C. and Baticle, E. and Pourrier, C. and Wolny, D. and Astagneau, P. and Kadi, Z. and Standard precautions work, group

Awareness of standard precautions for 4439 healthcare professionals in 34 institutions in France

Med Mal Infect (2013)

43, 10-6

10.1016/j.medmal.2012.11.004

Atmanene, C. and Ronin, C. and Teletchea, S. and Gautier, F. M. and Djedaini-Pilard, F. and Ciesielski, F. and Vivat, V. and Grandjean, C.

Biophysical and structural characterization of mono/di-arylated lactosamine derivatives interaction with human galectin-3

Biochem Biophys Res Commun (2017)

489, 281-286

10.1016/j.bbrc.2017.05.150

Aubry, S. and Aubert, G. and Cresteil, T. and Crich, D.

Synthesis and biological investigation of the beta-thiolactone and beta-lactam analogs of tetrahydrolipstatin

Org Biomol Chem (2012)

10, 2629-32

10.1039/c2ob06976h

Aubry, S. and Sasaki, K. and Eloy, L. and Aubert, G. and Retailleau, P. and Cresteil, T. and Crich, D.

Exploring the potential of the beta-thiolactones in bioorganic chemistry

Org Biomol Chem (2011)

9, 7134-43

10.1039/c1ob05967j

Audran, E. and Dagher, R. and Gioria, S. and Tsvetkov, P. O. and Kulikova, A. A. and Didier, B. and Villa, P. and Makarov, A. A. and Kilhoffer, M. C. and Haiech, J.

A general framework to characterize inhibitors of calmodulin: use of calmodulin inhibitors to study the interaction between calmodulin and its calmodulin binding domains

Biochim Biophys Acta (2013)

1833, 1720-31

10.1016/j.bbamcr.2013.01.008

Aulner, N. and Danckaert, A. and Rouault-Hardoin, E. and Desrivot, J. and Helynck, O. and Commere, P. H. and Munier-Lehmann, H. and Spath, G. F. and Shorte, S. L. and Milon, G. and Prina, E.

High content analysis of primary macrophages hosting proliferating Leishmania amastigotes: application to anti-leishmanial drug discovery

PLoS Negl Trop Dis (2013)

7, e2154

10.1371/journal.pntd.0002154

Austin, S. and Taouji, S. and Chevet, E. and Wodrich, H. and Rayne, F.

Using AlphaScreen((R)) to Identify Small-Molecule Inhibitors Targeting a Conserved Host-Pathogen Interaction

Methods Mol Biol (2016)

1449, 453-67

10.1007/978-1-4939-3756-1_30

Autelitano, F. and Loyaux, D. and Roudieres, S. and Deon, C. and Guette, F. and Fabre, P. and Ping, Q. and Wang, S. and Auvergne, R. and Badarinarayana, V. and Smith, M. and Guillemot, J. C. and Goldman, S. A. and Natesan, S. and Ferrara, P. and August, P.

Identification of novel tumor-associated cell surface sialoglycoproteins in human glioblastoma tumors using quantitative proteomics

PLoS One (2014)

9, e110316

10.1371/journal.pone.0110316

Avarre, J. C. and Dugue, R. and Alonso, P. and Diombokho, A. and Joffrois, C. and Faivre, N. and Cochet, C. and Durand, J. D.

Analysis of the black-chinned tilapia Sarotherodon melanotheron heudelotii reproducing under a wide range of salinities: from RNA-seq to candidate genes

Mol Ecol Resour (2014)

14, 139-49

10.1111/1755-0998.12148

Ayachi, S. and Simonin, F.

Involvement of Mammalian RF-Amide Peptides and Their Receptors in the Modulation of Nociception in Rodents

Front Endocrinol (Lausanne) (2014)

5, 158

10.3389/fendo.2014.00158

Ayoub, M. A. and Crepieux, P. and Koglin, M. and Parmentier, M. and Pin, J. P. and Poupon, A. and Reiter, E. and Smit, M. and Steyaert, J. and Watier, H. and Wilkinson, T.

Antibodies targeting G protein-coupled receptors: Recent advances and therapeutic challenges

MAbs (2017)

9, 735-741

10.1080/19420862.2017.1325052

Ayrolles-Torro, A. and Imberdis, T. and Torrent, J. and Toupet, K. and Baskakov, I. V. and Poncet-Montange, G. and Gregoire, C. and Roquet-Baneres, F. and Lehmann, S. and Rognan, D. and Pugniere, M. and Verdier, J. M. and Perrier, V.

Oligomeric-induced activity by thienyl pyrimidine compounds traps prion infectivity

J Neurosci (2011)

31, 14882-92

10.1523/JNEUROSCI.0547-11.2011

Azmi, M. N. and Geny, C. and Leverrier, A. and Litaudon, M. and Dumontet, V. and Birlirakis, N. and Gueritte, F. and Leong, K. H. and Halim, S. N. and Mohamad, K. and Awang, K.

Kingianic acids A-G, Endiandric acid analogues from Endiandra kingiana

Molecules (2014)

19, 1732-47

10.3390/molecules19021732

Bach-Segura, P. and Belarbi, N.

[Diagnostic imaging evaluation of neonatal vomiting]

J Radiol (2011)

92, 134-41

10.1016/j.jradio.2010.12.007

Baddour-Hadjean, R. and Boudaoud, A. and Bach, S. and Emery, N. and Pereira-Ramos, J. P.

A comparative insight of potassium vanadates as positive electrode materials for Li batteries: influence of the long-range and local structure

Inorg Chem (2014)

53, 1764-72

10.1021/ic402897d

Baklouti, A. and Goulet, A. and Lichiere, J. and Canard, B. and Charrel, R. N. and Ferron, F. and Coutard, B. and Papageorgiou, N.

Toscana virus nucleoprotein oligomer organization observed in solution

Acta Crystallogr D Struct Biol (2017)

73, 650-659

10.1107/S2059798317008774

Ballereau, S. and Levade, T. and Genisson, Y. and Andrieu-Abadie, N.

Alteration of ceramide 1-O-functionalization as a promising approach for cancer therapy

Anticancer Agents Med Chem (2012)

12, 316-28

Baratte, B. and Serive, B. and Bach, S.

[Screening marine resources to find novel chemical inhibitors of disease-relevant protein kinases]

Med Sci (Paris) (2015)

31, 538-45

10.1051/medsci/20153105016

Barbier, J. and Cintrat, J. C. and Gillet, D.

Intracellular pathogens convert macrophages from death traps into hospitable homes

FEBS J (2016)

283, 595-7

10.1111/febs.13657

Barelier, S. and Krimm, I.

Ligand specificity, privileged substructures and protein druggability from fragment-based screening

Curr Opin Chem Biol (2011)

15, 469-74

10.1016/j.cbpa.2011.02.020

Barelier, S. and Linard, D. and Pons, J. and Clippe, A. and Knoops, B. and Lancelin, J. M. and Krimm, I.

Discovery of fragment molecules that bind the human peroxiredoxin 5 active site

PLoS One (2010)

5, e9744

10.1371/journal.pone.0009744

Barelier, S. and Pons, J. and Gehring, K. and Lancelin, J. M. and Krimm, I.

Ligand specificity in fragment-based drug design

J Med Chem (2010)

53, 5256-66

10.1021/jm100496j

Barelier, S. and Pons, J. and Marcillat, O. and Lancelin, J. M. and Krimm, I.

Fragment-based deconstruction of Bcl-xL inhibitors

J Med Chem (2010)

53, 2577-88

10.1021/jm100009z

Barette, C. and Soleilhac, E. and Charavay, C. and Cochet, C. and Fauvarque, M. O.

[Strength and specificity of the CMBA screening platform for bioactive molecules discovery]

Med Sci (Paris) (2015)

31, 423-31

10.1051/medsci/20153104017

Barral, K. and Priet, S. and De Michelis, C. and Sire, J. and Neyts, J. and Balzarini, J. and Canard, B. and Alvarez, K.

Synthesis and antiviral activity of boranophosphonate isosteres of AZT and d4T monophosphates

Eur J Med Chem (2010)

45, 849-56

10.1016/j.ejmech.2009.11.012

Barral, K. and Sallamand, C. and Petzold, C. and Coutard, B. and Collet, A. and Thillier, Y. and Zimmermann, J. and Vasseur, J. J. and Canard, B. and Rohayem, J. and Debart, F. and Decroly, E.

Development of specific dengue virus 2'-O- and N7-methyltransferase assays for antiviral drug screening

Antiviral Res (2013)

99, 292-300

10.1016/j.antiviral.2013.06.001

Barral, K. and Weck, C. and Payrot, N. and Roux, L. and Durafour, C. and Zoulim, F. and Neyts, J. and Balzarini, J. and Canard, B. and Priet, S. and Alvarez, K.

Acyclic nucleoside thiophosphonates as potent inhibitors of HIV and HBV replication

Eur J Med Chem (2011)

46, 4281-8

10.1016/j.ejmech.2011.06.034

Barthe, P. and Veyron-Churlet, R. and de Visch, A. and Gilleron, M. and Saliou, J. M. and Tomavo, S. and Nigou, J. and Brodin, P. and Cohen-Gonsaud, M.

Mycobacterium tuberculosis LppM Displays an Original Structure and Domain Composition Linked to a Dual Localization

Structure (2016)

24, 1788-1794

10.1016/j.str.2016.07.009

Baskin, II and Kireeva, N. and Varnek, A.

The One-Class Classification Approach to Data Description and to Models Applicability Domain

Mol Inform (2010)

29, 581-7

10.1002/minf.201000063

Baskin, II and Solov'ev, V. P. and Bagatur'yants, A. A. and Varnek, A.

Predictive cartography of metal binders using generative topographic mapping

J Comput Aided Mol Des (2017)

31, 701-714

10.1007/s10822-017-0033-6

Basse, M. J. and Betzi, S. and Bourgeas, R. and Bouzidi, S. and Chetrit, B. and Hamon, V. and Morelli, X. and Roche, P.

2P2Idb: a structural database dedicated to orthosteric modulation of protein-protein interactions

Nucleic Acids Res (2013)

41, D824-7

10.1093/nar/gks1002

Basse, M. J. and Betzi, S. and Morelli, X. and Roche, P.

2P2Idb v2: update of a structural database dedicated to orthosteric modulation of protein-protein interactions

Database (Oxford) (2016)

2016,

10.1093/database/baw007

Baxter, P. N. and Al Ouahabi, A. and Gisselbrecht, J. P. and Brelot, L. and Varnek, A.

Electronic, spectroscopic, and ion-sensing properties of a dehydro[m]pyrido[14]- and [15]annulene isomer library

J Org Chem (2012)

77, 126-42

10.1021/jo201595s

Abboud, D. and Daubeuf, F. and Do, Q. T. and Utard, V. and Villa, P. and Haiech, J. and Bonnet, D. and Hibert, M. and Bernard, P. and Galzi, J. L. and Frossard, N.

A strategy to discover decoy chemokine ligands with an anti-inflammatory activity

Sci Rep (2015)

5, 14746

10.1038/srep14746

Abdelkafi, H. and Cintrat, J. C.

Regioselective Halogenation of 1,4-Benzodiazepinones via CH Activation

Sci Rep (2015)

5, 12131

10.1038/srep12131

Abdelkafi, H. and Michau, A. and Clerget, A. and Buisson, D. A. and Johannes, L. and Gillet, D. and Barbier, J. and Cintrat, J. C.

Synthesis, Chiral Separation, Absolute Configuration Assignment, and Biological Activity of Enantiomers of Retro-1 as Potent Inhibitors of Shiga Toxin

ChemMedChem (2015)

10, 1153-6

10.1002/cmdc.201500139

Abdelnabi, R. and Morais, A. T. S. and Leyssen, P. and Imbert, I. and Beaucourt, S. and Blanc, H. and Froeyen, M. and Vignuzzi, M. and Canard, B. and Neyts, J. and Delang, L.

Understanding the Mechanism of the Broad-Spectrum Antiviral Activity of Favipiravir (T-705): Key Role of the F1 Motif of the Viral Polymerase

J Virol (2017)

91,

10.1128/JVI.00487-17

Abida, H. and Ruchaud, S. and Rios, L. and Humeau, A. and Probert, I. and De Vargas, C. and Bach, S. and Bowler, C.

Bioprospecting marine plankton

Mar Drugs (2013)

11, 4594-611

10.3390/md11114594

Abou Samra, A. and Robert, A. and Gov, C. and Favre, L. and Eloy, L. and Jacquet, E. and Bignon, J. and Wiels, J. and Desrat, S. and Roussi, F.

Dual inhibitors of the pro-survival proteins Bcl-2 and Mcl-1 derived from natural compound meiogynin A

Eur J Med Chem (2018)

148, 26-38

10.1016/j.ejmech.2018.01.100

Abu-Helo, A. and Simonin, F.

Identification and biological significance of G protein-coupled receptor associated sorting proteins (GASPs)

Pharmacol Ther (2010)

126, 244-50

10.1016/j.pharmthera.2010.03.004

Aci-Seche, S. and Ziada, S. and Braka, A. and Arora, R. and Bonnet, P.

Advanced molecular dynamics simulation methods for kinase drug discovery

Future Med Chem (2016)

8, 545-66

10.4155/fmc.16.9

Adamska, A. and Rumijowska-Galewicz, A. and Ruszczynska, A. and Studzinska, M. and Jablonska, A. and Paradowska, E. and Bulska, E. and Munier-Lehmann, H. and Dziadek, J. and Lesnikowski, Z. J. and Olejniczak, A. B.

Anti-mycobacterial activity of thymine derivatives bearing boron clusters

Eur J Med Chem (2016)

121, 71-81

10.1016/j.ejmech.2016.05.030

Advedissian, T. and Deshayes, F. and Poirier, F. and Grandjean, C. and Viguier, M.

[Galectins, a class of unconventional lectins]

Med Sci (Paris) (2015)

31, 499-505

10.1051/medsci/20153105011

Agnaniet, H. and Mbot, E. J. and Keita, O. and Fehrentz, J. A. and Ankli, A. and Gallud, A. and Garcia, M. and Gary-Bobo, M. and Lebibi, J. and Cresteil, T. and Menut, C.

Antidiabetic potential of two medicinal plants used in Gabonese folk medicine

BMC Complement Altern Med (2016)

16, 71

10.1186/s12906-016-1052-x

Aguilar-Perez, C. and Gracia, B. and Rodrigues, L. and Vitoria, A. and Cebrian, R. and Deboosere, N. and Song, O. R. and Brodin, P. and Maqueda, M. and Ainsa, J. A.

Synergy between circular bacteriocin AS-48 and ethambutol against Mycobacterium tuberculosis

Antimicrob Agents Chemother (2018)

,

10.1128/AAC.00359-18

Aguilera, I. and Foraster, M. and Basagana, X. and Corradi, E. and Deltell, A. and Morelli, X. and Phuleria, H. C. and Ragettli, M. S. and Rivera, M. and Thomasson, A. and Slama, R. and Kunzli, N.

Application of land use regression modelling to assess the spatial distribution of road traffic noise in three European cities

J Expo Sci Environ Epidemiol (2015)

25, 97-105

10.1038/jes.2014.61

Aguirre, C. and ten Brink, T. and Cala, O. and Guichou, J. F. and Krimm, I.

Protein-ligand structure guided by backbone and side-chain proton chemical shift perturbations

J Biomol NMR (2014)

60, 147-56

10.1007/s10858-014-9864-9

Aguirre, C. and ten Brink, T. and Guichou, J. F. and Cala, O. and Krimm, I.

Comparing binding modes of analogous fragments using NMR in fragment-based drug design: application to PRDX5

PLoS One (2014)

9, e102300

10.1371/journal.pone.0102300

Aguirre, C. and Ten Brink, T. and Walker, O. and Guilliere, F. and Davesne, D. and Krimm, I.

BcL-xL conformational changes upon fragment binding revealed by NMR

PLoS One (2013)

8, e64400

10.1371/journal.pone.0064400

Ahmed-Belkacem, A. and Colliandre, L. and Ahnou, N. and Nevers, Q. and Gelin, M. and Bessin, Y. and Brillet, R. and Cala, O. and Douguet, D. and Bourguet, W. and Krimm, I. and Pawlotsky, J. M. and Guichou, J. F.

Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities

Nat Commun (2016)

7, 12777

10.1038/ncomms12777

Aillaud, C. and Bosc, C. and Peris, L. and Bosson, A. and Heemeryck, P. and Van Dijk, J. and Le Friec, J. and Boulan, B. and Vossier, F. and Sanman, L. E. and Syed, S. and Amara, N. and Coute, Y. and Lafanechere, L. and Denarier, E. and Delphin, C. and Pelletier, L. and Humbert, S. and Bogyo, M. and Andrieux, A. and Rogowski, K. and Moutin, M. J.

Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation

Science (2017)

358, 1448-1453

10.1126/science.aao4165

Aiyar, R. S. and Bohnert, M. and Duvezin-Caubet, S. and Voisset, C. and Gagneur, J. and Fritsch, E. S. and Couplan, E. and von der Malsburg, K. and Funaya, C. and Soubigou, F. and Courtin, F. and Suresh, S. and Kucharczyk, R. and Evrard, J. and Antony, C. and St Onge, R. P. and Blondel, M. and di Rago, J. P. and van der Laan, M. and Steinmetz, L. M.

Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders

Nat Commun (2014)

5, 5585

10.1038/ncomms6585

Al-Shuaeeb, R. A. and Kolodych, S. and Koniev, O. and Delacroix, S. and Erb, S. and Nicolay, S. and Cintrat, J. C. and Brion, J. D. and Cianferani, S. and Alami, M. and Wagner, A. and Messaoudi, S.

Palladium-Catalyzed Chemoselective and Biocompatible Functionalization of Cysteine-Containing Molecules at Room Temperature

Chemistry (2016)

22, 11365-70

10.1002/chem.201602277

Alabdul Magid, A. and Morjani, H. and Harakat, D. and Madoulet, C. and Dumontet, V. and Lavaud, C.

Triterpenoid glycosides from the leaves of Meliosma henryi

Phytochemistry (2015)

109, 49-56

10.1016/j.phytochem.2014.10.035

Alberto, C. and Konstantinou, M. P. and Martinage, C. and Casassa, E. and Tournier, E. and Bagheri, H. and Sibaud, V. and Mourey, L. and Mazereeuw-Hautier, J. and Meyer, N. and Paul, C. and Bulai Livideanu, C.

Enzalutamide induced acute generalized exanthematous pustulosis

J Dermatol Case Rep (2016)

10, 35-38

10.3315/jdcr.2016.1226

Albesa-Jove, D. and Svetlikova, Z. and Tersa, M. and Sancho-Vaello, E. and Carreras-Gonzalez, A. and Bonnet, P. and Arrasate, P. and Eguskiza, A. and Angala, S. K. and Cifuente, J. O. and Kordulakova, J. and Jackson, M. and Mikusova, K. and Guerin, M. E.

Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA

Nat Commun (2016)

7, 10906

10.1038/ncomms10906

Alborz, M. and Jarrahpour, A. and Pournejati, R. and Karbalaei-Heidari, H. R. and Sinou, V. and Latour, C. and Brunel, J. M. and Sharghi, H. and Aberi, M. and Turos, E. and Wojtas, L.

Synthesis and biological evaluation of some novel diastereoselective benzothiazole beta-lactam conjugates

Eur J Med Chem (2018)

143, 283-291

10.1016/j.ejmech.2017.11.053

Alexandre, T. and Raynal, B. and Munier-Lehmann, H.

Two classes of bacterial IMPDHs according to their quaternary structures and catalytic properties

PLoS One (2015)

10, e0116578

10.1371/journal.pone.0116578

Allam, A. and Maigre, L. and Vergalli, J. and Dumont, E. and Cinquin, B. and Alves de Sousa, R. and Pajovic, J. and Pinet, E. and Smith, N. and Herbeuval, J. P. and Refregiers, M. and Artaud, I. and Pages, J. M.

Microspectrofluorimetry to dissect the permeation of ceftazidime in Gram-negative bacteria

Sci Rep (2017)

7, 986

10.1038/s41598-017-00945-8

Allard, P. M. and Dau, E. T. and Eydoux, C. and Guillemot, J. C. and Dumontet, V. and Poullain, C. and Canard, B. and Gueritte, F. and Litaudon, M.

Alkylated flavanones from the bark of Cryptocarya chartacea as dengue virus NS5 polymerase inhibitors

J Nat Prod (2011)

74, 2446-53

10.1021/np200715v

Allard, P. M. and Leyssen, P. and Martin, M. T. and Bourjot, M. and Dumontet, V. and Eydoux, C. and Guillemot, J. C. and Canard, B. and Poullain, C. and Gueritte, F. and Litaudon, M.

Antiviral chlorinated daphnane diterpenoid orthoesters from the bark and wood of Trigonostemon cherrieri

Phytochemistry (2012)

84, 160-8

10.1016/j.phytochem.2012.07.023

Alligand, B. and Le Breton, M. and Marquis, D. and Vallette, F. and Fleury, F.

Functional effects of diphosphomimetic mutations at cAbl-mediated phosphorylation sites on Rad51 recombinase activity

Biochimie (2017)

139, 115-124

10.1016/j.biochi.2017.05.020

Allouche, M. and Pertuiset, C. and Robert, J. L. and Martel, C. and Veneziano, R. and Henry, C. and dein, O. S. and Saint, N. and Brenner, C. and Chopineau, J.

ANT-VDAC1 interaction is direct and depends on ANT isoform conformation in vitro

Biochem Biophys Res Commun (2012)

429, 12-7

10.1016/j.bbrc.2012.10.108

Baxter, P. N. and Gisselbrecht, J. P. and Karmazin-Brelot, L. and Varnek, A. and Allouche, L.

Synthesis of a strained acetylenic macrocycle incorporating a para-oligo[2]cruciform bridge bent over nanoscopic dimensions: structural, electronic, spectroscopic, and ion-sensing properties

Chemistry (2013)

19, 12336-49

10.1002/chem.201204569

Bazin, M. A. and Rousseau, B. and Marhadour, S. and Tomasoni, C. and Evenou, P. and Piessard, S. and Vaisberg, A. J. and Ruchaud, S. and Bach, S. and Roussakis, C. and Marchand, P.

Discovery of Novel (Imidazo[1,2-a]pyrazin-6-yl)ureas as Antiproliferative Agents Targeting P53 in Non-small Cell Lung Cancer Cell Lines

Anticancer Res (2016)

36, 1621-30

Beauvineau, C. and Guetta, C. and Teulade-Fichou, M. P. and Mahuteau-Betzer, F.

PhenDV, a turn-off fluorescent quadruplex DNA probe for improving the sensitivity of drug screening assays

Org Biomol Chem (2017)

15, 7117-7121

10.1039/c7ob01705g

Becker, J. A. and Le Merrer, J.

Long-Term Transcriptional Consequences of Drug Exposure as Cues to Understand Vulnerability to Relapse: Advances and Perspectives

J Stud Alcohol Drugs (2016)

77, 692-5

Becker, J. A. J. and Kieffer, B. L. and Le Merrer, J.

Differential behavioral and molecular alterations upon protracted abstinence from cocaine versus morphine, nicotine, THC and alcohol

Addict Biol (2017)

22, 1205-1217

10.1111/adb.12405

Becq, F.

Predicting CFTR activity with front-runner cystic fibrosis drugs

EBioMedicine (2015)

2, 100-1

10.1016/j.ebiom.2015.01.013

Becq, F. and Chanson, M.

Strategies to circumvent the CFTR defect in cystic fibrosis

Front Pharmacol (2013)

4, 108

10.3389/fphar.2013.00108

Becq, F. and Mall, M. A. and Sheppard, D. N. and Conese, M. and Zegarra-Moran, O.

Pharmacological therapy for cystic fibrosis: from bench to bedside

J Cyst Fibros (2011)

10 Suppl 2, S129-45

10.1016/S1569-1993(11)60018-0

Beedessee, G. and Ramanjooloo, A. and Aubert, G. and Eloy, L. and Surnam-Boodhun, R. and Soest, Rwmv and Cresteil, T. and Marie, D. E. P.

Cytotoxic activities of hexane, ethyl acetate and butanol extracts of marine sponges from Mauritian Waters on human cancer cell lines

Environ Toxicol Pharmacol (2012)

34, 397-408

10.1016/j.etap.2012.05.013

Beghyn, T. B. and Charton, J. and Leroux, F. and Henninot, A. and Reboule, I. and Cos, P. and Maes, L. and Deprez, B.

Drug-to-genome-to-drug, step 2: reversing selectivity in a series of antiplasmodial compounds

J Med Chem (2012)

55, 1274-86

10.1021/jm201422e

Beghyn, T. B. and Charton, J. and Leroux, F. and Laconde, G. and Bourin, A. and Cos, P. and Maes, L. and Deprez, B.

Drug to genome to drug: discovery of new antiplasmodial compounds

J Med Chem (2011)

54, 3222-40

10.1021/jm1014617

Belade, E. and Armand, L. and Martinon, L. and Kheuang, L. and Fleury-Feith, J. and Baeza-Squiban, A. and Lanone, S. and Billon-Galland, M. A. and Pairon, J. C. and Boczkowski, J.

A comparative transmission electron microscopy study of titanium dioxide and carbon black nanoparticles uptake in human lung epithelial and fibroblast cell lines

Toxicol In Vitro (2012)

26, 57-66

10.1016/j.tiv.2011.10.010

Beniddir, M. A. and Le Borgne, E. and Iorga, B. I. and Loaec, N. and Lozach, O. and Meijer, L. and Awang, K. and Litaudon, M.

Acridone alkaloids from Glycosmis chlorosperma as DYRK1A inhibitors

J Nat Prod (2014)

77, 1117-22

10.1021/np400856h

Benmansour, F. and Eydoux, C. and Querat, G. and de Lamballerie, X. and Canard, B. and Alvarez, K. and Guillemot, J. C. and Barral, K.

Novel 2-phenyl-5-[(E)-2-(thiophen-2-yl)ethenyl]-1,3,4-oxadiazole and 3-phenyl-5-[(E)-2-(thiophen-2-yl)ethenyl]-1,2,4-oxadiazole derivatives as dengue virus inhibitors targeting NS5 polymerase

Eur J Med Chem (2016)

109, 146-56

10.1016/j.ejmech.2015.12.046

Benz, N. and Le Hir, S. and Norez, C. and Kerbiriou, M. and Calvez, M. L. and Becq, F. and Trouve, P. and Ferec, C.

Improvement of chloride transport defect by gonadotropin-releasing hormone (GnRH) in cystic fibrosis epithelial cells

PLoS One (2014)

9, e88964

10.1371/journal.pone.0088964

Berard, E. and Bongard, V. and Dallongeville, J. and Arveiler, D. and Amouyel, P. and Wagner, A. and Cottel, D. and Haas, B. and Ruidavets, J. B. and Ferrieres, J.

Impact of cardiovascular risk factor control on long-term cardiovascular and all-cause mortality in the general population

Ann Med (2016)

48, 559-567

10.1080/07853890.2016.1217035

Berchel, M. and Le Gall, T. and Lozach, O. and Haelters, J. P. and Montier, T. and Jaffres, P. A.

Lipophosphoramidate-based bipolar amphiphiles: their syntheses and transfection properties

Org Biomol Chem (2016)

14, 2846-53

10.1039/c5ob02512e

Cam, M. and Durieu, E. and Bodin, M. and Manousopoulou, A. and Koslowski, S. and Vasylieva, N. and Barnych, B. and Hammock, B. D. and Bohl, B. and Koch, P. and Omori, C. and Yamamoto, K. and Hata, S. and Suzuki, T. and Karg, F. and Gizzi, P. and Haber, V. E. and Bencetic Mihaljevic, V. and Tavcar, B. and Portelius, E. and Pannee, J. and Blennow, K. and Zetterberg, H. and Garbis, S. D. and Auvray, P. and Gerber, H. and Fraering, J. and Fraering, P. C. and Meijer, L.

Induction of Amyloid-beta42 Production by Fipronil and Other Pyrazole Insecticides

J Alzheimers Dis (2018)

62, 1663-1681

10.3233/JAD-170875

Camara, D. and Bisanz, C. and Barette, C. and Van Daele, J. and Human, E. and Barnard, B. and Van der Straeten, D. and Stove, C. P. and Lambert, W. E. and Douce, R. and Marechal, E. and Birkholtz, L. M. and Cesbron-Delauw, M. F. and Dumas, R. and Rebeille, F.

Inhibition of p-aminobenzoate and folate syntheses in plants and apicomplexan parasites by natural product rubreserine

J Biol Chem (2012)

287, 22367-76

10.1074/jbc.M112.365833

Camare, C. and Vanucci-Bacque, C. and Auge, N. and Pucelle, M. and Bernis, C. and Swiader, A. and Baltas, M. and Bedos-Belval, F. and Salvayre, R. and Negre-Salvayre, A.

4-Hydroxynonenal Contributes to Angiogenesis through a Redox-Dependent Sphingolipid Pathway: Prevention by Hydralazine Derivatives

Oxid Med Cell Longev (2017)

2017, 9172741

10.1155/2017/9172741

Camassa, S. and Palucci, I. and Iantomasi, R. and Cubeddu, T. and Minerva, M. and De Maio, F. and Jouny, S. and Petruccioli, E. and Goletti, D. and Ria, F. and Sali, M. and Sanguinetti, M. and Manganelli, R. and Rocca, S. and Brodin, P. and Delogu, G.

Impact of pe_pgrs33 Gene Polymorphisms on Mycobacterium tuberculosis Infection and Pathogenesis

Front Cell Infect Microbiol (2017)

7, 137

10.3389/fcimb.2017.00137

Canal, F. and Anthony, E. and Lescure, A. and Del Nery, E. and Camonis, J. and Perez, F. and Ragazzon, B. and Perret, C.

A kinome siRNA screen identifies HGS as a potential target for liver cancers with oncogenic mutations in CTNNB1

BMC Cancer (2015)

15, 1020

10.1186/s12885-015-2037-8

Canault, B. and Bourg, S. and Vayer, P. and Bonnet, P.

Comprehensive Network Map of ADME-Tox Databases

Mol Inform (2017)

36,

10.1002/minf.201700029

Carette, X. and Blondiaux, N. and Willery, E. and Hoos, S. and Lecat-Guillet, N. and Lens, Z. and Wohlkonig, A. and Wintjens, R. and Soror, S. H. and Frenois, F. and Dirie, B. and Villeret, V. and England, P. and Lippens, G. and Deprez, B. and Locht, C. and Willand, N. and Baulard, A. R.

Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands

Nucleic Acids Res (2012)

40, 3018-30

10.1093/nar/gkr1113

Carles, F. and Bourg, S. and Meyer, C. and Bonnet, P.

PKIDB: A Curated, Annotated and Updated Database of Protein Kinase Inhibitors in Clinical Trials

Molecules (2018)

23,

10.3390/molecules23040908

Carmona-Gutierrez, D. and Bauer, M. A. and Zimmermann, A. and Aguilera, A. and Austriaco, N. and Ayscough, K. and Balzan, R. and Bar-Nun, S. and Barrientos, A. and Belenky, P. and Blondel, M. and Braun, R. J. and Breitenbach, M. and Burhans, W. C. and Buttner, S. and Cavalieri, D. and Chang, M. and Cooper, K. F. and Corte-Real, M. and Costa, V. and Cullin, C. and Dawes, I. and Dengjel, J. and Dickman, M. B. and Eisenberg, T. and Fahrenkrog, B. and Fasel, N. and Frohlich, K. U. and Gargouri, A. and Giannattasio, S. and Goffrini, P. and Gourlay, C. W. and Grant, C. M. and Greenwood, M. T. and Guaragnella, N. and Heger, T. and Heinisch, J. and Herker, E. and Herrmann, J. M. and Hofer, S. and Jimenez-Ruiz, A. and Jungwirth, H. and Kainz, K. and Kontoyiannis, D. P. and Ludovico, P. and Manon, S. and Martegani, E. and Mazzoni, C. and Megeney, L. A. and Meisinger, C. and Nielsen, J. and Nystrom, T. and Osiewacz, H. D. and Outeiro, T. F. and Park, H. O. and Pendl, T. and Petranovic, D. and Picot, S. and Polcic, P. and Powers, T. and Ramsdale, M. and Rinnerthaler, M. and Rockenfeller, P. and Ruckenstuhl, C. and Schaffrath, R. and Segovia, M. and Severin, F. F. and Sharon, A. and Sigrist, S. J. and Sommer-Ruck, C. and Sousa, M. J. and Thevelein, J. M. and Thevissen, K. and Titorenko, V. and Toledano, M. B. and Tuite, M. and Vogtle, F. N. and Westermann, B. and Winderickx, J. and Wissing, S. and Wolfl, S. and Zhang, Z. J. and Zhao, R. Y. and Zhou, B. and Galluzzi, L. and Kroemer, G. and Madeo, F.

Guidelines and recommendations on yeast cell death nomenclature

Microb Cell (2018)

5, 4-31

10.15698/mic2018.01.607

Carre, C. and Jacquier, C. and Bouge, A. L. and de Chaumont, F. and Besnard-Guerin, C. and Thomassin, H. and Pidoux, J. and Da Silva, B. and Chalatsi, E. and Zahra, S. and Olivo-Marin, J. C. and Munier-Lehmann, H. and Antoniewski, C.

AutomiG, a biosensor to detect alterations in miRNA biogenesis and in small RNA silencing guided by perfect target complementarity

PLoS One (2013)

8, e74296

10.1371/journal.pone.0074296

Berkes, D. and Daich, A. and Santos, C. and Ballereau, S. and Genisson, Y.

Chemistry and Biology of HPAs: A Family of Ceramide Trafficking Inhibitors

Chemistry (2016)

22, 17514-17525

10.1002/chem.201602947

Bernard, S. and Audisio, D. and Riomet, M. and Bregant, S. and Sallustrau, A. and Plougastel, L. and Decuypere, E. and Gabillet, S. and Kumar, R. A. and Elyian, J. and Trinh, M. N. and Koniev, O. and Wagner, A. and Kolodych, S. and Taran, F.

Bioorthogonal Click and Release Reaction of Iminosydnones with Cycloalkynes

Angew Chem Int Ed Engl (2017)

56, 15612-15616

10.1002/anie.201708790

Bertholdt, C. and Perdriolle-Galet, E. and Bach-Segura, P. and Morel, O.

Tracheal agenesis: a challenging prenatal diagnosis-contribution of fetal MRI

Case Rep Obstet Gynecol (2015)

2015, 456028

10.1155/2015/456028

Bertrand, J. and Dannhoffer, L. and Antigny, F. and Vachel, L. and Jayle, C. and Vandebrouck, C. and Becq, F. and Norez, C.

A functional tandem between transient receptor potential canonical channels 6 and calcium-dependent chloride channels in human epithelial cells

Eur J Pharmacol (2015)

765, 337-45

10.1016/j.ejphar.2015.08.005

Bestgen, B. and Belaid-Choucair, Z. and Lomberget, T. and Le Borgne, M. and Filhol, O. and Cochet, C.

In Search of Small Molecule Inhibitors Targeting the Flexible CK2 Subunit Interface

Pharmaceuticals (Basel) (2017)

10,

10.3390/ph10010016

Betzer, J. F. and Nuter, F. and Chtchigrovsky, M. and Hamon, F. and Kellermann, G. and Ali, S. and Calmejane, M. A. and Roque, S. and Poupon, J. and Cresteil, T. and Teulade-Fichou, M. P. and Marinetti, A. and Bombard, S.

Linking of Antitumor trans NHC-Pt(II) Complexes to G-Quadruplex DNA Ligand for Telomeric Targeting

Bioconjug Chem (2016)

27, 1456-70

10.1021/acs.bioconjchem.6b00079

Bignon, C. and Li, C. and Lichiere, J. and Canard, B. and Coutard, B.

Improving the soluble expression of recombinant proteins by randomly shuffling 5' and 3' coding-sequence ends

Acta Crystallogr D Biol Crystallogr (2013)

69, 2580-2

10.1107/S0907444913018751

Bihel, F. and Humbert, J. P. and Schneider, S. and Bertin, I. and Wagner, P. and Schmitt, M. and Laboureyras, E. and Petit-Demouliere, B. and Schneider, E. and Mollereau, C. and Simonnet, G. and Simonin, F. and Bourguignon, J. J.

Development of a peptidomimetic antagonist of neuropeptide FF receptors for the prevention of opioid-induced hyperalgesia

ACS Chem Neurosci (2015)

6, 438-45

10.1021/cn500219h

Bilan, R. and Fleury, F. and Nabiev, I. and Sukhanova, A.

Quantum dot surface chemistry and functionalization for cell targeting and imaging

Bioconjug Chem (2015)

26, 609-24

10.1021/acs.bioconjchem.5b00069

Billant, O. and Blondel, M. and Voisset, C.

p53, p63 and p73 in the wonderland of S. cerevisiae

Oncotarget (2017)

8, 57855-57869

10.18632/oncotarget.18506

Billant, O. and Leon, A. and Le Guellec, S. and Friocourt, G. and Blondel, M. and Voisset, C.

The dominant-negative interplay between p53, p63 and p73: A family affair

Oncotarget (2016)

7, 69549-69564

10.18632/oncotarget.11774

Billard, I. and Marcou, G. and Ouadi, A. and Varnek, A.

In silico design of new ionic liquids based on quantitative structure-property relationship models of ionic liquid viscosity

J Phys Chem B (2011)

115, 93-8

10.1021/jp107868w

Billet, A. and Froux, L. and Hanrahan, J. W. and Becq, F.

Development of Automated Patch Clamp Technique to Investigate CFTR Chloride Channel Function

Front Pharmacol (2017)

8, 195

10.3389/fphar.2017.00195

Billet, A. and Mornon, J. P. and Jollivet, M. and Lehn, P. and Callebaut, I. and Becq, F.

CFTR: effect of ICL2 and ICL4 amino acids in close spatial proximity on the current properties of the channel

J Cyst Fibros (2013)

12, 737-45

10.1016/j.jcf.2013.02.002

Blanc, L. and Gilleron, M. and Prandi, J. and Song, O. R. and Jang, M. S. and Gicquel, B. and Drocourt, D. and Neyrolles, O. and Brodin, P. and Tiraby, G. and Vercellone, A. and Nigou, J.

Mycobacterium tuberculosis inhibits human innate immune responses via the production of TLR2 antagonist glycolipids

Proc Natl Acad Sci U S A (2017)

114, 11205-11210

10.1073/pnas.1707840114

Blanchard, P. and Faivre, L. and Lesaunier, F. and Salem, N. and Mesgouez-Nebout, N. and Deniau-Alexandre, E. and Rolland, F. and Ferrero, J. M. and Houede, N. and Mourey, L. and Theodore, C. and Krakowski, I. and Berdah, J. F. and Baciuchka, M. and Laguerre, B. and Davin, J. L. and Habibian, M. and Culine, S. and Laplanche, A. and Fizazi, K.

Outcome According to Elective Pelvic Radiation Therapy in Patients With High-Risk Localized Prostate Cancer: A Secondary Analysis of the GETUG 12 Phase 3 Randomized Trial

Int J Radiat Oncol Biol Phys (2016)

94, 85-92

10.1016/j.ijrobp.2015.09.020

Blondel, M. and Soubigou, F. and Evrard, J. and Nguyen, P. H. and Hasin, N. and Chedin, S. and Gillet, R. and Contesse, M. A. and Friocourt, G. and Stahl, G. and Jones, G. W. and Voisset, C.

Protein Folding Activity of the Ribosome is involved in Yeast Prion Propagation

Sci Rep (2016)

6, 32117

10.1038/srep32117

Blondiaux, N. and Moune, M. and Desroses, M. and Frita, R. and Flipo, M. and Mathys, V. and Soetaert, K. and Kiass, M. and Delorme, V. and Djaout, K. and Trebosc, V. and Kemmer, C. and Wintjens, R. and Wohlkonig, A. and Antoine, R. and Huot, L. and Hot, D. and Coscolla, M. and Feldmann, J. and Gagneux, S. and Locht, C. and Brodin, P. and Gitzinger, M. and Deprez, B. and Willand, N. and Baulard, A. R.

Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420

Science (2017)

355, 1206-1211

10.1126/science.aag1006

Bode, S. A. and Thevenin, M. and Bechara, C. and Sagan, S. and Bregant, S. and Lavielle, S. and Chassaing, G. and Burlina, F.

Self-assembling mini cell-penetrating peptides enter by both direct translocation and glycosaminoglycan-dependent endocytosis

Chem Commun (Camb) (2012)

48, 7179-81

10.1039/c2cc33240j

Boeva, V. and Lermine, A. and Barette, C. and Guillouf, C. and Barillot, E.

Nebula--a web-server for advanced ChIP-seq data analysis

Bioinformatics (2012)

28, 2517-9

10.1093/bioinformatics/bts463

Boinot, C. and Jollivet Souchet, M. and Ferru-Clement, R. and Becq, F.

Searching for combinations of small-molecule correctors to restore f508del-cystic fibrosis transmembrane conductance regulator function and processing

J Pharmacol Exp Ther (2014)

350, 624-34

10.1124/jpet.114.214890

Boiteau, J. G. and Ouvry, G. and Arlabosse, J. M. and Astri, S. and Beillard, A. and Bhurruth-Alcor, Y. and Bonnary, L. and Bouix-Peter, C. and Bouquet, K. and Bourotte, M. and Cardinaud, I. and Comino, C. and Deprez, B. and Duvert, D. and Feret, A. and Hacini-Rachinel, F. and Harris, C. S. and Luzy, A. P. and Mathieu, A. and Millois, C. and Orsini, N. and Pascau, J. and Pinto, A. and Piwnica, D. and Polge, G. and Reitz, A. and Reverse, K. and Rodeville, N. and Rossio, P. and Spiesse, D. and Tabet, S. and Taquet, N. and Tomas, L. and Vial, E. and Hennequin, L. F.

Discovery and process development of a novel TACE inhibitor for the topical treatment of psoriasis

Bioorg Med Chem (2018)

26, 945-956

10.1016/j.bmc.2017.07.054

Bollenbach, M. and Salvat, E. and Daubeuf, F. and Wagner, P. and Yalcin, I. and Humo, M. and Letellier, B. and Becker, L. J. and Bihel, F. and Bourguignon, J. J. and Villa, P. and Obrecht, A. and Frossard, N. and Barrot, M. and Schmitt, M.

Phenylpyridine-2-ylguanidines and rigid mimetics as novel inhibitors of TNFalpha overproduction: Beneficial action in models of neuropathic pain and of acute lung inflammation

Eur J Med Chem (2018)

147, 163-182

10.1016/j.ejmech.2018.01.049

Bolton, P. R. and Borghesi, M. and Brenner, C. and Carroll, D. C. and De Martinis, C. and Fiorini, F. and Flacco, A. and Floquet, V. and Fuchs, J. and Gallegos, P. and Giove, D. and Green, J. S. and Green, S. and Jones, B. and Kirby, D. and McKenna, P. and Neely, D. and Nuesslin, F. and Prasad, R. and Reinhardt, S. and Roth, M. and Schramm, U. and Scott, G. G. and Ter-Avetisyan, S. and Tolley, M. and Turchetti, G. and Wilkens, J. J.

Instrumentation for diagnostics and control of laser-accelerated proton (ion) beams

Phys Med (2014)

30, 255-70

10.1016/j.ejmp.2013.09.002

Bonachera, F. and Marcou, G. and Kireeva, N. and Varnek, A. and Horvath, D.

Using self-organizing maps to accelerate similarity search

Bioorg Med Chem (2012)

20, 5396-409

10.1016/j.bmc.2012.04.024

Boncompain, G. and Divoux, S. and Gareil, N. and de Forges, H. and Lescure, A. and Latreche, L. and Mercanti, V. and Jollivet, F. and Raposo, G. and Perez, F.

Synchronization of secretory protein traffic in populations of cells

Nat Methods (2012)

9, 493-8

10.1038/nmeth.1928

Bongard, V. and Arveiler, D. and Dallongeville, J. and Ruidavets, J. B. and Wagner, A. and Simon, C. and Marecaux, N. and Ferrieres, J.

Food groups associated with a reduced risk of 15-year all-cause death

Eur J Clin Nutr (2016)

70, 715-22

10.1038/ejcn.2016.19

Bonneau, N. and Cynober, T. and Jullian, J. C. and Champy, P.

(1) H qNMR Quantification of Annonaceous Acetogenins in Crude Extracts of Annona muricata L. Fruit Pulp

Phytochem Anal (2017)

28, 251-256

10.1002/pca.2668

Bonnel, D. and Legouffe, R. and Willand, N. and Baulard, A. and Hamm, G. and Deprez, B. and Stauber, J.

MALDI imaging techniques dedicated to drug-distribution studies

Bioanalysis (2011)

3, 1399-406

10.4155/bio.11.88

Bonner, C. and Kerr-Conte, J. and Gmyr, V. and Queniat, G. and Moerman, E. and Thevenet, J. and Beaucamps, C. and Delalleau, N. and Popescu, I. and Malaisse, W. J. and Sener, A. and Deprez, B. and Abderrahmani, A. and Staels, B. and Pattou, F.

Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion

Nat Med (2015)

21, 512-7

10.1038/nm.3828

Bonnet, D. and Margathe, J. F. and Radford, S. and Pflimlin, E. and Riche, S. and Doman, P. and Hibert, M. and Ganesan, A.

Combinatorial aid for underprivileged scaffolds: solution and solid-phase strategies for a rapid and efficient access to novel aza-diketopiperazines (Aza-DKP)

ACS Comb Sci (2012)

14, 323-34

10.1021/co300015k

Bordes, P. and Sala, A. J. and Ayala, S. and Texier, P. and Slama, N. and Cirinesi, A. M. and Guillet, V. and Mourey, L. and Genevaux, P.

Chaperone addiction of toxin-antitoxin systems

Nat Commun (2016)

7, 13339

10.1038/ncomms13339

Borie, R. and Wislez, M. and Antoine, M. and Fleury-Feith, J. and Thabut, G. and Crestani, B. and Monnet, I. and Nunes, H. and Delfau-Larue, M. H. and Cadranel, J.

Clonality and phenotyping analysis of alveolar lymphocytes is suggestive of pulmonary MALT lymphoma

Respir Med (2011)

105, 1231-7

10.1016/j.rmed.2011.03.018

Borie, R. and Wislez, M. and Fleury-Feith, J. and Delfau-Larue, M. H. and Cadranel, J.

MALT1 Rearrangements in BAL Fluid

Chest (2012)

142, 262

10.1378/chest.12-0275

Bornert, O. and Moller, T. C. and Boeuf, J. and Candusso, M. P. and Wagner, R. and Martinez, K. L. and Simonin, F.

Identification of a novel protein-protein interaction motif mediating interaction of GPCR-associated sorting proteins with G protein-coupled receptors

PLoS One (2013)

8, e56336

10.1371/journal.pone.0056336

Bornet, O. and Nouailler, M. and Feracci, M. and Sebban-Kreuzer, C. and Byrne, D. and Halimi, H. and Morelli, X. and Badache, A. and Guerlesquin, F.

Identification of a Src kinase SH3 binding site in the C-terminal domain of the human ErbB2 receptor tyrosine kinase

FEBS Lett (2014)

588, 2031-6

10.1016/j.febslet.2014.04.029

Bosc, D. and Jakhlal, J. and Deprez, B. and Deprez-Poulain, R.

Kinetic target-guided synthesis in drug discovery and chemical biology: a comprehensive facts and figures survey

Future Med Chem (2016)

8, 381-404

10.4155/fmc-2015-0007

Bosc, N. and Kuenemann, M. A. and Becot, J. and Vavrusa, M. and Cerdan, A. H. and Sperandio, O.

Privileged Substructures to Modulate Protein-Protein Interactions

J Chem Inf Model (2017)

57, 2448-2462

10.1021/acs.jcim.7b00435

Bosc, N. and Meyer, C. and Bonnet, P.

The use of novel selectivity metrics in kinase research

BMC Bioinformatics (2017)

18, 17

10.1186/s12859-016-1413-y

Bosc, N. and Wroblowski, B. and Aci-Seche, S. and Meyer, C. and Bonnet, P.

A Proteometric Analysis of Human Kinome: Insight into Discriminant Conformation-dependent Residues

ACS Chem Biol (2015)

10, 2827-40

10.1021/acschembio.5b00555

Bosc, N. and Wroblowski, B. and Meyer, C. and Bonnet, P.

Prediction of Protein Kinase-Ligand Interactions through 2.5D Kinochemometrics

J Chem Inf Model (2017)

57, 93-101

10.1021/acs.jcim.6b00520

Bosseboeuf, A. and Feron, D. and Tallet, A. and Rossi, C. and Charlier, C. and Garderet, L. and Caillot, D. and Moreau, P. and Cardo-Vila, M. and Pasqualini, R. and Arap, W. and Nelson, A. D. and Wilson, B. S. and Perreault, H. and Piver, E. and Weigel, P. and Girodon, F. and Harb, J. and Bigot-Corbel, E. and Hermouet, S.

Monoclonal IgG in MGUS and multiple myeloma targets infectious pathogens

JCI Insight (2017)

2,

10.1172/jci.insight.95367

Bottai, D. and Frigui, W. and Clark, S. and Rayner, E. and Zelmer, A. and Andreu, N. and de Jonge, M. I. and Bancroft, G. J. and Williams, A. and Brodin, P. and Brosch, R.

Increased protective efficacy of recombinant BCG strains expressing virulence-neutral proteins of the ESX-1 secretion system

Vaccine (2015)

33, 2710-8

10.1016/j.vaccine.2015.03.083

Botte, C. Y. and Deligny, M. and Roccia, A. and Bonneau, A. L. and Saidani, N. and Hardre, H. and Aci, S. and Yamaryo-Botte, Y. and Jouhet, J. and Dubots, E. and Loizeau, K. and Bastien, O. and Brehelin, L. and Joyard, J. and Cintrat, J. C. and Falconet, D. and Block, M. A. and Rousseau, B. and Lopez, R. and Marechal, E.

Chemical inhibitors of monogalactosyldiacylglycerol synthases in Arabidopsis thaliana

Nat Chem Biol (2011)

7, 834-42

10.1038/nchembio.658

Boucherle, B. and Bertrand, J. and Maurin, B. and Renard, B. L. and Fortune, A. and Tremblier, B. and Becq, F. and Norez, C. and Decout, J. L.

A new 9-alkyladenine-cyclic methylglyoxal diadduct activates wt- and F508del-cystic fibrosis transmembrane conductance regulator (CFTR) in vitro and in vivo

Eur J Med Chem (2014)

83, 455-65

10.1016/j.ejmech.2014.06.028

Bouchery, T. and Denece, G. and Attout, T. and Ehrhardt, K. and Lhermitte-Vallarino, N. and Hachet-Haas, M. and Galzi, J. L. and Brotin, E. and Bachelerie, F. and Gavotte, L. and Moulia, C. and Bain, O. and Martin, C.

The chemokine CXCL12 is essential for the clearance of the filaria Litomosoides sigmodontis in resistant mice

PLoS One (2012)

7, e34971

10.1371/journal.pone.0034971

Boudenot, A. and Maurel, D. B. and Pallu, S. and Ingrand, I. and Boisseau, N. and Jaffre, C. and Portier, H.

Quick benefits of interval training versus continuous training on bone: a dual-energy X-ray absorptiometry comparative study

Int J Exp Pathol (2015)

96, 370-7

10.1111/iep.12155

Boudiaf-Benmammar, C. and Cresteil, T. and Melki, R.

The cytosolic chaperonin CCT/TRiC and cancer cell proliferation

PLoS One (2013)

8, e60895

10.1371/journal.pone.0060895

Boulahjar, R. and Ouach, A. and Bourg, S. and Bonnet, P. and Lozach, O. and Meijer, L. and Guguen-Guillouzo, C. and Le Guevel, R. and Lazar, S. and Akssira, M. and Troin, Y. and Guillaumet, G. and Routier, S.

Advances in tetrahydropyrido[1,2-a]isoindolone (valmerins) series: Potent glycogen synthase kinase 3 and cyclin dependent kinase 5 inhibitors

Eur J Med Chem (2015)

101, 274-87

10.1016/j.ejmech.2015.06.046

Boulahjar, R. and Ouach, A. and Matteo, C. and Bourg, S. and Ravache, M. and le Guevel, R. and Marionneau, S. and Oullier, T. and Lozach, O. and Meijer, L. and Guguen-Guillouzo, C. and Lazar, S. and Akssira, M. and Troin, Y. and Guillaumet, G. and Routier, S.

Novel tetrahydropyrido[1,2-a]isoindolone derivatives (valmerins): potent cyclin-dependent kinase/glycogen synthase kinase 3 inhibitors with antiproliferative activities and antitumor effects in human tumor xenografts

J Med Chem (2012)

55, 9589-606

10.1021/jm3008536

Boulle, F. and Velthuis, H. and Koedam, K. and Steinbusch, H. W. and van den Hove, D. L. A. and Kenis, G. and Gabriel, C. and Mocaer, E. and Franc, B. and Rognan, D. and Mongeau, R. and Lanfumey, L.

Behavioral and neurochemical characterization of TrkB-dependent mechanisms of agomelatine in glucocorticoid receptor-impaired mice

Eur Neuropsychopharmacol (2016)

26, 65-77

10.1016/j.euroneuro.2015.11.003

Bourd-Boittin, K. and Bonnier, D. and Leyme, A. and Mari, B. and Tuffery, P. and Samson, M. and Ezan, F. and Baffet, G. and Theret, N.

Protease profiling of liver fibrosis reveals the ADAM metallopeptidase with thrombospondin type 1 motif, 1 as a central activator of transforming growth factor beta

Hepatology (2011)

54, 2173-84

10.1002/hep.24598

Bourgeas, R. and Basse, M. J. and Morelli, X. and Roche, P.

Atomic analysis of protein-protein interfaces with known inhibitors: the 2P2I database

PLoS One (2010)

5, e9598

10.1371/journal.pone.0009598

Bourjot, M. and Leyssen, P. and Eydoux, C. and Guillemot, J. C. and Canard, B. and Rasoanaivo, P. and Gueritte, F. and Litaudon, M.

Flacourtosides A-F, phenolic glycosides isolated from Flacourtia ramontchi

J Nat Prod (2012)

75, 752-8

10.1021/np300059n

Bourjot, M. and Leyssen, P. and Eydoux, C. and Guillemot, J. C. and Canard, B. and Rasoanaivo, P. and Gueritte, F. and Litaudon, M.

Chemical constituents of Anacolosa pervilleana and their antiviral activities

Fitoterapia (2012)

83, 1076-80

10.1016/j.fitote.2012.05.004

Bourjot, M. and Leyssen, P. and Neyts, J. and Dumontet, V. and Litaudon, M.

Trigocherrierin A, a potent inhibitor of chikungunya virus replication

Molecules (2014)

19, 3617-27

10.3390/molecules19033617

Bourkhis, M. and Gaspard, H. and Rulliere, P. and de Almeida, D. K. C. and Listunov, D. and Joly, E. and Abderrahim, R. and de Mattos, M. C. and de Oliveira, M. C. F. and Maraval, V. and Chauvin, R. and Genisson, Y.

Skeletal Optimization of Cytotoxic Lipidic Dialkynylcarbinols

ChemMedChem (2018)

13, 1124-1130

10.1002/cmdc.201800118

Boussouar, A. and Barette, C. and Nadon, R. and Saint-Leger, A. and Broucqsault, N. and Ottaviani, A. and Firozhoussen, A. and Lu, Y. and Lafanechere, L. and Gilson, E. and Magdinier, F. and Ye, J.

Acacetin and chrysin, two polyphenolic compounds, alleviate telomeric position effect in human cells

Mol Ther Nucleic Acids (2013)

2, e116

10.1038/mtna.2013.42

Bouvet, M. and Lugari, A. and Posthuma, C. C. and Zevenhoven, J. C. and Bernard, S. and Betzi, S. and Imbert, I. and Canard, B. and Guillemot, J. C. and Lecine, P. and Pfefferle, S. and Drosten, C. and Snijder, E. J. and Decroly, E. and Morelli, X.

Coronavirus Nsp10, a critical co-factor for activation of multiple replicative enzymes

J Biol Chem (2014)

289, 25783-96

10.1074/jbc.M114.577353

Brenner, C. and Galluzzi, L. and Kepp, O. and Kroemer, G.

Decoding cell death signals in liver inflammation

J Hepatol (2013)

59, 583-94

10.1016/j.jhep.2013.03.033

Brenner, C. and Lemoine, A.

Mitochondrial Proteins (e.g., VDAC, Bcl-2, HK, ANT) as Major Control Points in Oncology

Front Oncol (2014)

4, 365

10.3389/fonc.2014.00365

Brenner, C. and Luciani, J. and Bizet, M. and Ndlovu, M. and Josseaux, E. and Dedeurwaerder, S. and Calonne, E. and Putmans, P. and Cartron, P. F. and Defrance, M. and Fuks, F. and Deplus, R.

The interplay between the lysine demethylase KDM1A and DNA methyltransferases in cancer cells is cell cycle dependent

Oncotarget (2016)

7, 58939-58952

10.18632/oncotarget.10624

Brenner, C. and Moulin, M.

Physiological roles of the permeability transition pore

Circ Res (2012)

111, 1237-47

10.1161/CIRCRESAHA.112.265942

Brenner, C. and Ventura-Clapier, R. and Jacotot, E.

Mitochondria and cytoprotection

Biochem Res Int (2012)

2012, 351264

10.1155/2012/351264

Breuer, S. and Espinola, S. and Morelli, X. and Torbett, B. E. and Arold, S. T. and Engels, I. H.

A Biochemical/Biophysical Assay Dyad for HTS-Compatible Triaging of Inhibitors of the HIV-1 Nef/Hck SH3 Interaction

Curr Chem Genom Transl Med (2013)

7, 16-20

10.2174/2213988501307010016

Brien, G. and Debaud, A. L. and Bickle, M. and Trescol-Biemont, M. C. and Moncorge, O. and Colas, P. and Bonnefoy-Berard, N.

Characterization of peptide aptamers targeting Bfl-1 anti-apoptotic protein

Biochemistry (2011)

50, 5120-9

10.1021/bi101839p

Brillet, K. and Reimmann, C. and Mislin, G. L. and Noel, S. and Rognan, D. and Schalk, I. J. and Cobessi, D.

Pyochelin enantiomers and their outer-membrane siderophore transporters in fluorescent pseudomonads: structural bases for unique enantiospecific recognition

J Am Chem Soc (2011)

133, 16503-9

10.1021/ja205504z

Brison, Y. and Malbert, Y. and Czaplicki, G. and Mourey, L. and Remaud-Simeon, M. and Tranier, S.

Structural Insights into the Carbohydrate Binding Ability of an alpha-(1-->2) Branching Sucrase from Glycoside Hydrolase Family 70

J Biol Chem (2016)

291, 7527-40

10.1074/jbc.M115.688796

Broad, J. and Maurel, D. and Kung, V. W. and Hicks, G. A. and Schemann, M. and Barnes, M. R. and Kenakin, T. P. and Granier, S. and Sanger, G. J.

Human native kappa opioid receptor functions not predicted by recombinant receptors: Implications for drug design

Sci Rep (2016)

6, 30797

10.1038/srep30797

Brodin, P. and DelNery, E. and Soleilhac, E.

[High content screening in chemical biology: overview and main challenges]

Med Sci (Paris) (2015)

31, 187-96

10.1051/medsci/20153102016

Broeders, E. P. and Nascimento, E. B. and Havekes, B. and Brans, B. and Roumans, K. H. and Tailleux, A. and Schaart, G. and Kouach, M. and Charton, J. and Deprez, B. and Bouvy, N. D. and Mottaghy, F. and Staels, B. and van Marken Lichtenbelt, W. D. and Schrauwen, P.

The Bile Acid Chenodeoxycholic Acid Increases Human Brown Adipose Tissue Activity

Cell Metab (2015)

22, 418-26

10.1016/j.cmet.2015.07.002

Brossard, D. and Retailleau, P. and Dumontet, V. and Breton, P. and Desrat, S. and Roussi, F.

Fast preparation of 3D scaffolds from methyl benzoate by a diversity oriented synthesis strategy based on Diels-Alder and ene-reactions

Org Biomol Chem (2017)

15, 5585-5592

10.1039/c7ob01236e

Brossard, D. and Zhang, Y. and Haider, S. M. and Sgobba, M. and Khalid, M. and Legay, R. and Duterque-Coquillaud, M. and Galera, P. and Rault, S. and Dallemagne, P. and Moslemi, S. and El Kihel, L.

N-substituted piperazinopyridylsteroid derivatives as abiraterone analogues inhibit growth and induce pro-apoptosis in human hormone-independent prostate cancer cell lines

Chem Biol Drug Des (2013)

82, 620-9

10.1111/cbdd.12195

Bruel, A. and Beneteau, R. and Chabanne, M. and Lozach, O. and Le Guevel, R. and Ravache, M. and Benedetti, H. and Meijer, L. and Loge, C. and Robert, J. M.

Synthesis of new pyridazino[4,5-b]indol-4-ones and pyridazin-3(2H)-one analogs as DYRK1A inhibitors

Bioorg Med Chem Lett (2014)

24, 5037-40

10.1016/j.bmcl.2014.09.017

Bruel, A. and Loge, C. and Tauzia, M. L. and Ravache, M. and Le Guevel, R. and Guillouzo, C. and Lohier, J. F. and Oliveira Santos, J. S. and Lozach, O. and Meijer, L. and Ruchaud, S. and Benedetti, H. and Robert, J. M.

Synthesis and biological evaluation of new 5-benzylated 4-oxo-3,4-dihydro-5H-pyridazino[4,5-b]indoles as PI3Kalpha inhibitors

Eur J Med Chem (2012)

57, 225-33

10.1016/j.ejmech.2012.09.001

Brule, C. and Perzo, N. and Joubert, J. E. and Sainsily, X. and Leduc, R. and Castel, H. and Prezeau, L.

Biased signaling regulates the pleiotropic effects of the urotensin II receptor to modulate its cellular behaviors

FASEB J (2014)

28, 5148-62

10.1096/fj.14-249771

Bruzzoni-Giovanelli, H. and Alezra, V. and Wolff, N. and Dong, C. Z. and Tuffery, P. and Rebollo, A.

Interfering peptides targeting protein-protein interactions: the next generation of drugs?

Drug Discov Today (2018)

23, 272-285

10.1016/j.drudis.2017.10.016

Bruzzoni-Giovanelli, H. and Gonzalez, J. R. and Sigaux, F. and Villoutreix, B. O. and Cayuela, J. M. and Guilhot, J. and Preudhomme, C. and Guilhot, F. and Poyet, J. L. and Rousselot, P.

Genetic polymorphisms associated with increased risk of developing chronic myelogenous leukemia

Oncotarget (2015)

6, 36269-77

10.18632/oncotarget.5915

Buchieri, M. V. and Cimino, M. and Rebollo-Ramirez, S. and Beauvineau, C. and Cascioferro, A. and Favre-Rochex, S. and Helynck, O. and Naud-Martin, D. and Larrouy-Maumus, G. and Munier-Lehmann, H. and Gicquel, B.

Nitazoxanide Analogs Require Nitroreduction for Antimicrobial Activity in Mycobacterium smegmatis

J Med Chem (2017)

60, 7425-7433

10.1021/acs.jmedchem.7b00726

Buffel, I. and Meurs, A. and Portelli, J. and Raedt, R. and De Herdt, V. and Poppe, L. and De Meulenaere, V. and Wadman, W. and Bihel, F. and Schmitt, M. and Vonck, K. and Bourguignon, J. J. and Simonin, F. and Smolders, I. and Boon, P.

The effect of neuropeptide FF in the amygdala kindling model

Acta Neurol Scand (2016)

134, 181-8

10.1111/ane.12526

Burchak, O. N. and Pihive, E. L. and Maigre, L. and Guinchard, X. and Bouhours, P. and Jolivalt, C. and Schneider, D. and Maurin, M. and Giglione, C. and Meinnel, T. and Paris, J. M. and Denis, J. N.

Synthesis and evaluation of 1-(1H-indol-3-yl)ethanamine derivatives as new antibacterial agents

Bioorg Med Chem (2011)

19, 3204-15

10.1016/j.bmc.2011.03.060

Butkinaree, C. and Canuel, M. and Essalmani, R. and Poirier, S. and Benjannet, S. and Asselin, M. C. and Roubtsova, A. and Hamelin, J. and Marcinkiewicz, J. and Chamberland, A. and Guillemot, J. and Mayer, G. and Sisodia, S. S. and Jacob, Y. and Prat, A. and Seidah, N. G.

Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other

J Biol Chem (2015)

290, 18609-20

10.1074/jbc.M115.647180

Bzeih, T. and Lamaa, D. and Frison, G. and Hachem, A. and Jaber, N. and Bignon, J. and Retailleau, P. and Alami, M. and Hamze, A.

Csp(2)-Csp(2) and Csp(2)-N Bond Formation in a One-Pot Reaction between N-Tosylhydrazones and Bromonitrobenzenes: An Unexpected Cyclization to Substituted Indole Derivatives

Org Lett (2017)

19, 6700-6703

10.1021/acs.orglett.7b03422

Bzeih, T. and Naret, T. and Hachem, A. and Jaber, N. and Khalaf, A. and Bignon, J. and Brion, J. D. and Alami, M. and Hamze, A.

A general synthesis of arylindoles and (1-arylvinyl)carbazoles via a one-pot reaction from N-tosylhydrazones and 2-nitro-haloarenes and their potential application to colon cancer

Chem Commun (Camb) (2016)

52, 13027-13030

10.1039/c6cc07666a

Cabarrou, B. and Mourey, L. and Dalenc, F. and Balardy, L. and Kanoun, D. and Roche, H. and Boher, J. M. and Rouge-Bugat, M. E. and Filleron, T.

Methodology of phase II clinical trials in metastatic elderly breast cancer: a literature review

Breast Cancer Res Treat (2017)

164, 505-513

10.1007/s10549-017-4278-5

Cala, O. and Guilliere, F. and Krimm, I.

NMR-based analysis of protein-ligand interactions

Anal Bioanal Chem (2014)

406, 943-56

10.1007/s00216-013-6931-0

Cala, O. and Krimm, I.

Ligand-Orientation Based Fragment Selection in STD NMR Screening

J Med Chem (2015)

58, 8739-42

10.1021/acs.jmedchem.5b01114

Calland, N. and Sahuc, M. E. and Belouzard, S. and Pene, V. and Bonnafous, P. and Mesalam, A. A. and Deloison, G. and Descamps, V. and Sahpaz, S. and Wychowski, C. and Lambert, O. and Brodin, P. and Duverlie, G. and Meuleman, P. and Rosenberg, A. R. and Dubuisson, J. and Rouille, Y. and Seron, K.

Polyphenols Inhibit Hepatitis C Virus Entry by a New Mechanism of Action

J Virol (2015)

89, 10053-63

10.1128/JVI.01473-15

De Bantel, A. and Fleury-Feith, J. and Poirot, C. and Berthaut, I. and Garcin, C. and Landais, P. and Ravel, C.

Simultaneous vitality and DNA-fragmentation measurement in spermatozoa of smokers and non-smokers

Cytometry B Clin Cytom (2015)

88, 120-4

10.1002/cyto.b.21185

de Bourayne, M. and Gallais, Y. and El Ali, Z. and Rousseau, P. and Damiens, M. H. and Cochet, C. and Filhol, O. and Chollet-Martin, S. and Pallardy, M. and Kerdine-Romer, S.

Protein kinase CK2 controls T-cell polarization through dendritic cell activation in response to contact sensitizers

J Leukoc Biol (2017)

101, 703-715

10.1189/jlb.3A0715-320RR

de Fatima Pereira, M. and Rochais, C. and Dallemagne, P.

Recent Advances in Phenanthroindolizidine and Phenanthroquinolizidine Derivatives with Anticancer Activities

Anticancer Agents Med Chem (2015)

15, 1080-91

de Graaf, C. and Rein, C. and Piwnica, D. and Giordanetto, F. and Rognan, D.

Structure-based discovery of allosteric modulators of two related class B G-protein-coupled receptors

ChemMedChem (2011)

6, 2159-69

10.1002/cmdc.201100317

de Luca, A. and Horvath, D. and Marcou, G. and Solov'ev, V. and Varnek, A.

Mining chemical reactions using neighborhood behavior and condensed graphs of reactions approaches

J Chem Inf Model (2012)

52, 2325-38

10.1021/ci300149n

de Prost, N. and Parrot, A. and Cuquemelle, E. and Picard, C. and Antoine, M. and Fleury-Feith, J. and Mayaud, C. and Boffa, J. J. and Fartoukh, M. and Cadranel, J.

Diffuse alveolar hemorrhage in immunocompetent patients: etiologies and prognosis revisited

Respir Med (2012)

106, 1021-32

10.1016/j.rmed.2012.03.015

De Santis, M. and Wiechno, P. J. and Bellmunt, J. and Lucas, C. and Su, W. C. and Albiges, L. and Lin, C. C. and Senkus-Konefka, E. and Flechon, A. and Mourey, L. and Necchi, A. and Loidl, W. C. and Retz, M. M. and Vaissiere, N. and Culine, S.

Vinflunine-gemcitabine versus vinflunine-carboplatin as first-line chemotherapy in cisplatin-unfit patients with advanced urothelial carcinoma: results of an international randomized phase II trial (JASINT1)

Ann Oncol (2016)

27, 449-54

10.1093/annonc/mdv609

Debdab, M. and Carreaux, F. and Renault, S. and Soundararajan, M. and Fedorov, O. and Filippakopoulos, P. and Lozach, O. and Babault, L. and Tahtouh, T. and Baratte, B. and Ogawa, Y. and Hagiwara, M. and Eisenreich, A. and Rauch, U. and Knapp, S. and Meijer, L. and Bazureau, J. P.

Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing

J Med Chem (2011)

54, 4172-86

10.1021/jm200274d

Deboosere, N. and Iantomasi, R. and Queval, C. J. and Song, O. R. and Deloison, G. and Jouny, S. and Debrie, A. S. and Chamaillard, M. and Nigou, J. and Cohen-Gonsaud, M. and Locht, C. and Brodin, P. and Veyron-Churlet, R.

LppM impact on the colonization of macrophages by Mycobacterium tuberculosis

Cell Microbiol (2017)

19,

10.1111/cmi.12619

Decavele, M. and Gounant, V. and Fleury Feith, J. and Febvre, M. and Naccache, J. M. and Parrot, A. and Fartoukh, M.

Endobronchial ultrasound-guided transbronchial needle aspiration is feasible, safe, and reaches a 90 % diagnostic yield in patients with hypoxemic acute respiratory failure

Intensive Care Med (2016)

42, 1295-8

10.1007/s00134-016-4377-5

Decroly, E. and Canard, B.

Biochemical principles and inhibitors to interfere with viral capping pathways

Curr Opin Virol (2017)

24, 87-96

10.1016/j.coviro.2017.04.003

Degli Esposti, D. and Sebagh, M. and Pham, P. and Reffas, M. and Pous, C. and Brenner, C. and Azoulay, D. and Lemoine, A.

Ischemic preconditioning induces autophagy and limits necrosis in human recipients of fatty liver grafts, decreasing the incidence of rejection episodes

Cell Death Dis (2011)

2, e111

10.1038/cddis.2010.89

Dehbi, O. and Tikad, A. and Bourg, S. and Bonnet, P. and Lozach, O. and Meijer, L. and Aadil, M. and Akssira, M. and Guillaumet, G. and Routier, S.

Synthesis and optimization of an original V-shaped collection of 4-7-disubstituted pyrido[3,2-d]pyrimidines as CDK5 and DYRK1A inhibitors

Eur J Med Chem (2014)

80, 352-63

10.1016/j.ejmech.2014.04.055

Delang, L. and Li, C. and Tas, A. and Querat, G. and Albulescu, I. C. and De Burghgraeve, T. and Guerrero, N. A. and Gigante, A. and Piorkowski, G. and Decroly, E. and Jochmans, D. and Canard, B. and Snijder, E. J. and Perez-Perez, M. J. and van Hemert, M. J. and Coutard, B. and Leyssen, P. and Neyts, J.

The viral capping enzyme nsP1: a novel target for the inhibition of chikungunya virus infection

Sci Rep (2016)

6, 31819

10.1038/srep31819

Carre, G. and Carreyre, H. and Ouedraogo, M. and Becq, F. and Bois, P. and Thibaudeau, S. and Vandebrouck, C. and Bescond, J.

The hypotensive agent dodoneine inhibits L-type Ca2+ current with negative inotropic effect on rat heart

Eur J Pharmacol (2014)

728, 119-27

10.1016/j.ejphar.2014.01.059

Carre, G. and Ouedraogo, M. and Magaud, C. and Carreyre, H. and Becq, F. and Bois, P. and Supuran, C. T. and Thibaudeau, S. and Vandebrouck, C. and Bescond, J.

Vasorelaxation induced by dodoneine is mediated by calcium channels blockade and carbonic anhydrase inhibition on vascular smooth muscle cells

J Ethnopharmacol (2015)

169, 8-17

10.1016/j.jep.2015.03.037

Cartier-Michaud, A. and Bailly, A. L. and Betzi, S. and Shi, X. and Lissitzky, J. C. and Zarubica, A. and Serge, A. and Roche, P. and Lugari, A. and Hamon, V. and Bardin, F. and Derviaux, C. and Lembo, F. and Audebert, S. and Marchetto, S. and Durand, B. and Borg, J. P. and Shi, N. and Morelli, X. and Aurrand-Lions, M.

Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis

PLoS Genet (2017)

13, e1006803

10.1371/journal.pgen.1006803

Caruso, A. and Sinicropi, M. S. and Lancelot, J. C. and El-Kashef, H. and Saturnino, C. and Aubert, G. and Ballandonne, C. and Lesnard, A. and Cresteil, T. and Dallemagne, P. and Rault, S.

Synthesis and evaluation of cytotoxic activities of new guanidines derived from carbazoles

Bioorg Med Chem Lett (2014)

24, 467-72

10.1016/j.bmcl.2013.12.047

Caspar, Y. and Jeanty, M. and Blu, J. and Burchak, O. and Le Pihive, E. and Maigre, L. and Schneider, D. and Jolivalt, C. and Paris, J. M. and Hequet, A. and Minassian, F. and Denis, J. N. and Maurin, M.

Novel synthetic bis-indolic derivatives with antistaphylococcal activity, including against MRSA and VISA strains

J Antimicrob Chemother (2015)

70, 1727-37

10.1093/jac/dkv015

Castel, H. and Desrues, L. and Joubert, J. E. and Tonon, M. C. and Prezeau, L. and Chabbert, M. and Morin, F. and Gandolfo, P.

The G Protein-Coupled Receptor UT of the Neuropeptide Urotensin II Displays Structural and Functional Chemokine Features

Front Endocrinol (Lausanne) (2017)

8, 76

10.3389/fendo.2017.00076

Castets, P. and Bertrand, A. T. and Beuvin, M. and Ferry, A. and Le Grand, F. and Castets, M. and Chazot, G. and Rederstorff, M. and Krol, A. and Lescure, A. and Romero, N. B. and Guicheney, P. and Allamand, V.

Satellite cell loss and impaired muscle regeneration in selenoprotein N deficiency

Hum Mol Genet (2011)

20, 694-704

10.1093/hmg/ddq515

Catharina, L. and Lima, C. R. and Franca, A. and Guimaraes, A. C. R. and Alves-Ferreira, M. and Tuffery, P. and Derreumaux, P. and Carels, N.

A Computational Methodology to Overcome the Challenges Associated With the Search for Specific Enzyme Targets to Develop Drugs Against Leishmania major

Bioinform Biol Insights (2017)

11, 1177932217712471

10.1177/1177932217712471

Cavoue, T. and Emery, N. and Umirov, N. and Bach, S. and Berger, P. and Bakenov, Z. and Cenac-Morthe, C. and Pereira-Ramos, J. P.

Li2.0Ni0.67N, a Promising Negative Electrode Material for Li-Ion Batteries with a Soft Structural Response

Inorg Chem (2017)

56, 13815-13821

10.1021/acs.inorgchem.7b01903

Ceccato, L. and Chicanne, G. and Nahoum, V. and Pons, V. and Payrastre, B. and Gaits-Iacovoni, F. and Viaud, J.

PLIF: A rapid, accurate method to detect and quantitatively assess protein-lipid interactions

Sci Signal (2016)

9, rs2

10.1126/scisignal.aad4337

Cendret, V. and Legigan, T. and Mingot, A. and Thibaudeau, S. and Adachi, I. and Forcella, M. and Parenti, P. and Bertrand, J. and Becq, F. and Norez, C. and Desire, J. and Kato, A. and Bleriot, Y.

Synthetic deoxynojirimycin derivatives bearing a thiolated, fluorinated or unsaturated N-alkyl chain: identification of potent alpha-glucosidase and trehalase inhibitors as well as F508del-CFTR correctors

Org Biomol Chem (2015)

13, 10734-44

10.1039/c5ob01526j

Chaikuad, A. and Diharce, J. and Schroder, M. and Foucourt, A. and Leblond, B. and Casagrande, A. S. and Desire, L. and Bonnet, P. and Knapp, S. and Besson, T.

An Unusual Binding Model of the Methyl 9-Anilinothiazolo[5,4-f] quinazoline-2-carbimidates (EHT 1610 and EHT 5372) Confers High Selectivity for Dual-Specificity Tyrosine Phosphorylation-Regulated Kinases

J Med Chem (2016)

59, 10315-10321

10.1021/acs.jmedchem.6b01083

Chapuis, J. and Flaig, A. and Grenier-Boley, B. and Eysert, F. and Pottiez, V. and Deloison, G. and Vandeputte, A. and Ayral, A. M. and Mendes, T. and Desai, S. and Goate, A. M. and Kauwe, J. S. K. and Leroux, F. and Herledan, A. and Demiautte, F. and Bauer, C. and Checler, F. and Petersen, R. C. and Blennow, K. and Zetterberg, H. and Minthon, L. and Van Deerlin, V. M. and Lee, V. M. and Shaw, L. M. and Trojanowski, J. Q. and Albert, M. and Moghekar, A. and O'Brien, R. and Peskind, E. R. and Malmanche, N. and Schellenberg, G. D. and Dourlen, P. and Song, O. R. and Cruchaga, C. and Amouyel, P. and Deprez, B. and Brodin, P. and Lambert, J. C. and Adgc, Alzheimer's Disease Neuroimaging Initiative

Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism

Acta Neuropathol (2017)

133, 955-966

10.1007/s00401-016-1652-z

Charbord, J. and Poydenot, P. and Bonnefond, C. and Feyeux, M. and Casagrande, F. and Brinon, B. and Francelle, L. and Auregan, G. and Guillermier, M. and Cailleret, M. and Viegas, P. and Nicoleau, C. and Martinat, C. and Brouillet, E. and Cattaneo, E. and Peschanski, M. and Lechuga, M. and Perrier, A. L.

High throughput screening for inhibitors of REST in neural derivatives of human embryonic stem cells reveals a chemical compound that promotes expression of neuronal genes

Stem Cells (2013)

31, 1816-28

10.1002/stem.1430

Charton, J. and Gauriot, M. and Guo, Q. and Hennuyer, N. and Marechal, X. and Dumont, J. and Hamdane, M. and Pottiez, V. and Landry, V. and Sperandio, O. and Flipo, M. and Buee, L. and Staels, B. and Leroux, F. and Tang, W. J. and Deprez, B. and Deprez-Poulain, R.

Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-beta hydrolysis

Eur J Med Chem (2014)

79, 184-93

10.1016/j.ejmech.2014.04.009

Charton, J. and Gauriot, M. and Totobenazara, J. and Hennuyer, N. and Dumont, J. and Bosc, D. and Marechal, X. and Elbakali, J. and Herledan, A. and Wen, X. and Ronco, C. and Gras-Masse, H. and Heninot, A. and Pottiez, V. and Landry, V. and Staels, B. and Liang, W. G. and Leroux, F. and Tang, W. J. and Deprez, B. and Deprez-Poulain, R.

Structure-activity relationships of imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, dual binders of human insulin-degrading enzyme

Eur J Med Chem (2015)

90, 547-67

10.1016/j.ejmech.2014.12.005

Chatrin, C. and Talapatra, S. K. and Canard, B. and Kozielski, F.

The structure of the binary methyltransferase-SAH complex from Zika virus reveals a novel conformation for the mechanism of mRNA capping

Oncotarget (2018)

9, 3160-3171

10.18632/oncotarget.23223

Chaubet, G. and Coursindel, T. and Morelli, X. and Betzi, S. and Roche, P. and Guari, Y. and Lebrun, A. and Toupet, L. and Collette, Y. and Parrot, I. and Martinez, J.

Stereoselective synthesis of original spirolactams displaying promising folded structures

Org Biomol Chem (2013)

11, 4719-26

10.1039/c3ob40643a

Chaumontet, C. and Even, P. C. and Schwarz, J. and Simonin-Foucault, A. and Piedcoq, J. and Fromentin, G. and Azzout-Marniche, D. and Tome, D.

High dietary protein decreases fat deposition induced by high-fat and high-sucrose diet in rats

Br J Nutr (2015)

114, 1132-42

10.1017/S000711451500238X

Chauvin, C. and Leruste, A. and Tauziede-Espariat, A. and Andrianteranagna, M. and Surdez, D. and Lescure, A. and Han, Z. Y. and Anthony, E. and Richer, W. and Baulande, S. and Bohec, M. and Zaidi, S. and Aynaud, M. M. and Maillot, L. and Masliah-Planchon, J. and Cairo, S. and Roman-Roman, S. and Delattre, O. and Del Nery, E. and Bourdeaut, F.

High-Throughput Drug Screening Identifies Pazopanib and Clofilium Tosylate as Promising Treatments for Malignant Rhabdoid Tumors

Cell Rep (2017)

21, 1737-1745

10.1016/j.celrep.2017.10.076

Chen, W. and Zebaze, L. N. and Dong, J. and Chezeau, L. and Inquimbert, P. and Hugel, S. and Niu, S. and Bihel, F. and Boutant, E. and Real, E. and Villa, P. and Junier, M. P. and Chneiweiss, H. and Hibert, M. and Haiech, J. and Kilhoffer, M. C. and Zeniou, M.

WNK1 kinase and its partners Akt, SGK1 and NBC-family Na(+)/HCO3(-) cotransporters are potential therapeutic targets for glioblastoma stem-like cells linked to Bisacodyl signaling

Oncotarget (2018)

9, 27197-27219

10.18632/oncotarget.25509

Chevaleyre, C. and Riou, M. and Brea, D. and Vandebrouck, C. and Barc, C. and Pezant, J. and Melo, S. and Olivier, M. and Delaunay, R. and Boulesteix, O. and Berthon, P. and Rossignol, C. and Burlaud Gaillard, J. and Becq, F. and Gauthier, F. and Si-Tahar, M. and Meurens, F. and Berri, M. and Caballero-Posadas, I. and Attucci, S.

The Pig: A Relevant Model for Evaluating the Neutrophil Serine Protease Activities during Acute Pseudomonas aeruginosa Lung Infection

PLoS One (2016)

11, e0168577

10.1371/journal.pone.0168577

Chevillard, F. and Lagorce, D. and Reynes, C. and Villoutreix, B. O. and Vayer, P. and Miteva, M. A.

In silico prediction of aqueous solubility: a multimodel protocol based on chemical similarity

Mol Pharm (2012)

9, 3127-35

10.1021/mp300234q

Chicoulaa, B. and Balardy, L. and Stillmunkes, A. and Mourey, L. and Oustric, S. and Rouge Bugat, M. E.

French general practitioners' sense of isolation in the management of elderly cancer patients

Fam Pract (2016)

33, 551-6

10.1093/fampra/cmw034

Chollet, A. and Maveyraud, L. and Lherbet, C. and Bernardes-Genisson, V.

An overview on crystal structures of InhA protein: Apo-form, in complex with its natural ligands and inhibitors

Eur J Med Chem (2018)

146, 318-343

10.1016/j.ejmech.2018.01.047

Chollet, A. and Mori, G. and Menendez, C. and Rodriguez, F. and Fabing, I. and Pasca, M. R. and Madacki, J. and Kordulakova, J. and Constant, P. and Quemard, A. and Bernardes-Genisson, V. and Lherbet, C. and Baltas, M.

Design, synthesis and evaluation of new GEQ derivatives as inhibitors of InhA enzyme and Mycobacterium tuberculosis growth

Eur J Med Chem (2015)

101, 218-35

10.1016/j.ejmech.2015.06.035

Chollet, A. and Mourey, L. and Lherbet, C. and Delbot, A. and Julien, S. and Baltas, M. and Bernadou, J. and Pratviel, G. and Maveyraud, L. and Bernardes-Genisson, V.

Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach

J Struct Biol (2015)

190, 328-37

10.1016/j.jsb.2015.04.008

Chosson, E. and Santoro, F. and Rochais, C. and Santos, J. S. and Legay, R. and Thoret, S. and Cresteil, T. and Sinicropi, M. S. and Besson, T. and Dallemagne, P.

Synthesis of novel 7-oxo and 7-hydroxy trifluoroallocolchicinoids with cytotoxic effect

Bioorg Med Chem (2012)

20, 2614-23

10.1016/j.bmc.2012.02.043

Chow, K. Y. and Brotin, E. and Ben Khalifa, Y. and Carthagena, L. and Teissier, S. and Danckaert, A. and Galzi, J. L. and Arenzana-Seisdedos, F. and Thierry, F. and Bachelerie, F.

A pivotal role for CXCL12 signaling in HPV-mediated transformation of keratinocytes: clues to understanding HPV-pathogenesis in WHIM syndrome

Cell Host Microbe (2010)

8, 523-33

10.1016/j.chom.2010.11.006

Chtchigrovsky, M. and Eloy, L. and Jullien, H. and Saker, L. and Segal-Bendirdjian, E. and Poupon, J. and Bombard, S. and Cresteil, T. and Retailleau, P. and Marinetti, A.

Antitumor trans-N-heterocyclic carbene-amine-Pt(II) complexes: synthesis of dinuclear species and exploratory investigations of DNA binding and cytotoxicity mechanisms

J Med Chem (2013)

56, 2074-86

10.1021/jm301780s

Chupakhin, V. and Marcou, G. and Baskin, I. and Varnek, A. and Rognan, D.

Predicting ligand binding modes from neural networks trained on protein-ligand interaction fingerprints

J Chem Inf Model (2013)

53, 763-72

10.1021/ci300200r

Chupakhin, V. and Marcou, G. and Gaspar, H. and Varnek, A.

Simple Ligand-Receptor Interaction Descriptor (SILIRID) for alignment-free binding site comparison

Comput Struct Biotechnol J (2014)

10, 33-7

10.1016/j.csbj.2014.05.004

Clavaud, C. and Beauvais, A. and Barbin, L. and Munier-Lehmann, H. and Latge, J. P.

The composition of the culture medium influences the beta-1,3-glucan metabolism of Aspergillus fumigatus and the antifungal activity of inhibitors of beta-1,3-glucan synthesis

Antimicrob Agents Chemother (2012)

56, 3428-31

10.1128/AAC.05661-11

Cobret, L. and De Tauzia, M. L. and Ferent, J. and Traiffort, E. and Henaoui, I. and Godin, F. and Kellenberger, E. and Rognan, D. and Pantel, J. and Benedetti, H. and Morisset-Lopez, S.

Targeting the cis-dimerization of LINGO-1 with low MW compounds affects its downstream signalling

Br J Pharmacol (2015)

172, 841-56

10.1111/bph.12945

Cohen, A. and Suzanne, P. and Lancelot, J. C. and Verhaeghe, P. and Lesnard, A. and Basmaciyan, L. and Hutter, S. and Laget, M. and Dumetre, A. and Paloque, L. and Deharo, E. and Crozet, M. D. and Rathelot, P. and Dallemagne, P. and Lorthiois, A. and Sibley, C. H. and Vanelle, P. and Valentin, A. and Mazier, D. and Rault, S. and Azas, N.

Discovery of new thienopyrimidinone derivatives displaying antimalarial properties toward both erythrocytic and hepatic stages of Plasmodium

Eur J Med Chem (2015)

95, 16-28

10.1016/j.ejmech.2015.03.011

Colin, D. Y. and Deprez-Beauclair, P. and Silva, N. and Infantes, L. and Kerfelec, B.

Modification of pancreatic lipase properties by directed molecular evolution

Protein Eng Des Sel (2010)

23, 365-73

10.1093/protein/gzq008

Compain, P. and Decroocq, C. and Joosten, A. and de Sousa, J. and Rodriguez-Lucena, D. and Butters, T. D. and Bertrand, J. and Clement, R. and Boinot, C. and Becq, F. and Norez, C.

Rescue of functional CFTR channels in cystic fibrosis: a dramatic multivalent effect using iminosugar cluster-based correctors

Chembiochem (2013)

14, 2050-8

10.1002/cbic.201300312

Comps-Agrar, L. and Kniazeff, J. and Norskov-Lauritsen, L. and Maurel, D. and Gassmann, M. and Gregor, N. and Prezeau, L. and Bettler, B. and Durroux, T. and Trinquet, E. and Pin, J. P.

The oligomeric state sets GABA(B) receptor signalling efficacy

EMBO J (2011)

30, 2336-49

10.1038/emboj.2011.143

Comps-Agrar, L. and Maurel, D. and Rondard, P. and Pin, J. P. and Trinquet, E. and Prezeau, L.

Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to G protein-coupled receptor oligomerization

Methods Mol Biol (2011)

756, 201-14

10.1007/978-1-61779-160-4_10

Conraux, L. and Pech, C. and Guerraoui, H. and Loyaux, D. and Ferrara, P. and Guillemot, J. C. and Meininger, V. and Pradat, P. F. and Salachas, F. and Bruneteau, G. and Le Forestier, N. and Lacomblez, L.

Plasma peptide biomarker discovery for amyotrophic lateral sclerosis by MALDI-TOF mass spectrometry profiling

PLoS One (2013)

8, e79733

10.1371/journal.pone.0079733

Conte, M. and Lupette, J. and Seddiki, K. and Mei, C. and Dolch, L. J. and Gros, V. and Barette, C. and Rebeille, F. and Jouhet, J. and Marechal, E.

Screening for Biologically Annotated Drugs That Trigger Triacylglycerol Accumulation in the Diatom Phaeodactylum

Plant Physiol (2018)

177, 532-552

10.1104/pp.17.01804

Contesto-Richefeu, C. and Tarbouriech, N. and Brazzolotto, X. and Betzi, S. and Morelli, X. and Burmeister, W. P. and Iseni, F.

Crystal structure of the vaccinia virus DNA polymerase holoenzyme subunit D4 in complex with the A20 N-terminal domain

PLoS Pathog (2014)

10, e1003978

10.1371/journal.ppat.1003978

Coppin, E. and Gelsi-Boyer, V. and Morelli, X. and Cervera, N. and Murati, A. and Pandolfi, P. P. and Birnbaum, D. and Nunes, J. A.

Mutational analysis of the DOK2 haploinsufficient tumor suppressor gene in chronic myelomonocytic leukemia (CMML)

Leukemia (2015)

29, 500-2

10.1038/leu.2014.288

Coppin, L. and Vincent, A. and Frenois, F. and Duchene, B. and Lahdaoui, F. and Stechly, L. and Renaud, F. and Villenet, C. and Van Seuningen, I. and Leteurtre, E. and Dion, J. and Grandjean, C. and Poirier, F. and Figeac, M. and Delacour, D. and Porchet, N. and Pigny, P.

Galectin-3 is a non-classic RNA binding protein that stabilizes the mucin MUC4 mRNA in the cytoplasm of cancer cells

Sci Rep (2017)

7, 43927

10.1038/srep43927

Corbel, C. and Sartini, S. and Levati, E. and Colas, P. and Maillet, L. and Couturier, C. and Montanini, B. and Bach, S.

Screening for Protein-Protein Interaction Inhibitors Using a Bioluminescence Resonance Energy Transfer (BRET)-Based Assay in Yeast

SLAS Discov (2017)

22, 751-759

10.1177/2472555216689530

Corbel, C. and Wang, Q. and Bousserouel, H. and Hamdi, A. and Zhang, B. and Lozach, O. and Ferandin, Y. and Tan, V. B. and Gueritte, F. and Colas, P. and Couturier, C. and Bach, S.

First BRET-based screening assay performed in budding yeast leads to the discovery of CDK5/p25 interaction inhibitors

Biotechnol J (2011)

6, 860-70

10.1002/biot.201100138

Corbel, C. and Zhang, B. and Le Parc, A. and Baratte, B. and Colas, P. and Couturier, C. and Kosik, K. S. and Landrieu, I. and Le Tilly, V. and Bach, S.

Tamoxifen inhibits CDK5 kinase activity by interacting with p35/p25 and modulates the pattern of tau phosphorylation

Chem Biol (2015)

22, 472-482

10.1016/j.chembiol.2015.03.009

Corlay, N. and Lecso-Bornet, M. and Leborgne, E. and Blanchard, F. and Cachet, X. and Bignon, J. and Roussi, F. and Butel, M. J. and Awang, K. and Litaudon, M.

Antibacterial Labdane Diterpenoids from Vitex vestita

J Nat Prod (2015)

78, 1348-56

10.1021/acs.jnatprod.5b00206

Cortes, S. and Barette, C. and Beroud, R. and De Waard, M. and Schaack, B.

Functional characterization of cell-free expressed Kv1.3 channel using a voltage-sensitive fluorescent dye

Protein Expr Purif (2018)

145, 94-99

10.1016/j.pep.2018.01.006

Costa-Gouveia, J. and Ainsa, J. A. and Brodin, P. and Lucia, A.

How can nanoparticles contribute to antituberculosis therapy?

Drug Discov Today (2017)

22, 600-607

10.1016/j.drudis.2017.01.011

Costa-Gouveia, J. and Pancani, E. and Jouny, S. and Machelart, A. and Delorme, V. and Salzano, G. and Iantomasi, R. and Piveteau, C. and Queval, C. J. and Song, O. R. and Flipo, M. and Deprez, B. and Saint-Andre, J. P. and Hureaux, J. and Majlessi, L. and Willand, N. and Baulard, A. and Brodin, P. and Gref, R.

Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles

Sci Rep (2017)

7, 5390

10.1038/s41598-017-05453-3

Costa-Gouveia, J. and Pancani, E. and Jouny, S. and Machelart, A. and Delorme, V. and Salzano, G. and Iantomasi, R. and Piveteau, C. and Queval, C. J. and Song, O. R. and Flipo, M. and Deprez, B. and Saint-Andre, J. P. and Hureaux, J. and Majlessi, L. and Willand, N. and Baulard, A. and Brodin, P. and Gref, R.

Publisher Correction: Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles

Sci Rep (2018)

8, 7596

10.1038/s41598-018-25177-2

Cottet, M. and Faklaris, O. and Maurel, D. and Scholler, P. and Doumazane, E. and Trinquet, E. and Pin, J. P. and Durroux, T.

BRET and Time-resolved FRET strategy to study GPCR oligomerization: from cell lines toward native tissues

Front Endocrinol (Lausanne) (2012)

3, 92

10.3389/fendo.2012.00092

Coulerie, P. and Eydoux, C. and Hnawia, E. and Stuhl, L. and Maciuk, A. and Lebouvier, N. and Canard, B. and Figadere, B. and Guillemot, J. C. and Nour, M.

Biflavonoids of Dacrydium balansae with potent inhibitory activity on dengue 2 NS5 polymerase

Planta Med (2012)

78, 672-7

10.1055/s-0031-1298355

Courilleau, D. and Bisserier, M. and Jullian, J. C. and Lucas, A. and Bouyssou, P. and Fischmeister, R. and Blondeau, J. P. and Lezoualc'h, F.

Identification of a tetrahydroquinoline analog as a pharmacological inhibitor of the cAMP-binding protein Epac

J Biol Chem (2012)

287, 44192-202

10.1074/jbc.M112.422956

Courilleau, D. and Bouyssou, P. and Fischmeister, R. and Lezoualc'h, F. and Blondeau, J. P.

The (R)-enantiomer of CE3F4 is a preferential inhibitor of human exchange protein directly activated by cyclic AMP isoform 1 (Epac1)

Biochem Biophys Res Commun (2013)

440, 443-8

10.1016/j.bbrc.2013.09.107

Courtade-Saidi, M. and Fleury Feith, J. and Sous l'egide de la Societe francaise de cytologie, clinique

[Pre-analytical quality in fluid samples cytopathology: Results of a survey from the French Society of Clinical Cytology]

Ann Pathol (2015)

35, 378-86

10.1016/j.annpat.2015.08.019

Courtois, G. and Fauvarque, M. O.

The Many Roles of Ubiquitin in NF-kappaB Signaling

Biomedicines (2018)

6,

10.3390/biomedicines6020043

Cousin, F. J. and Jouan-Lanhouet, S. and Theret, N. and Brenner, C. and Jouan, E. and Le Moigne-Muller, G. and Dimanche-Boitrel, M. T. and Jan, G.

The probiotic Propionibacterium freudenreichii as a new adjuvant for TRAIL-based therapy in colorectal cancer

Oncotarget (2016)

7, 7161-78

10.18632/oncotarget.6881

Coutard, B. and Barral, K. and Lichiere, J. and Selisko, B. and Martin, B. and Aouadi, W. and Lombardia, M. O. and Debart, F. and Vasseur, J. J. and Guillemot, J. C. and Canard, B. and Decroly, E.

Zika Virus Methyltransferase: Structure and Functions for Drug Design Perspectives

J Virol (2017)

91,

10.1128/JVI.02202-16

Couturier, C. and Deprez, B.

Setting Up a Bioluminescence Resonance Energy Transfer High throughput Screening Assay to Search for Protein/Protein Interaction Inhibitors in Mammalian Cells

Front Endocrinol (Lausanne) (2012)

3, 100

10.3389/fendo.2012.00100

Crauste, C. and Willand, N. and Villemagne, B. and Flipo, M. and Willery, E. and Carette, X. and Dimala, M. M. and Drucbert, A. S. and Danze, P. M. and Deprez, B. and Baulard, A. R.

Unconventional surface plasmon resonance signals reveal quantitative inhibition of transcriptional repressor EthR by synthetic ligands

Anal Biochem (2014)

452, 54-66

10.1016/j.ab.2014.02.011

Crequit, P. and Wislez, M. and Fleury Feith, J. and Rozensztajn, N. and Jabot, L. and Friard, S. and Lavole, A. and Gounant, V. and Fillon, J. and Antoine, M. and Cadranel, J.

Crizotinib Associated with Ground-Glass Opacity Predominant Pattern Interstitial Lung Disease: A Retrospective Observational Cohort Study with a Systematic Literature Review

J Thorac Oncol (2015)

10, 1148-55

10.1097/JTO.0000000000000577

Cukier, C. D. and Maveyraud, L. and Saurel, O. and Guillet, V. and Milon, A. and Gervais, V.

The C-terminal region of the transcriptional regulator THAP11 forms a parallel coiled-coil domain involved in protein dimerization

J Struct Biol (2016)

194, 337-46

10.1016/j.jsb.2016.03.010

Cukier, C. D. and Tourdes, A. and El-Mazouni, D. and Guillet, V. and Nomme, J. and Mourey, L. and Milon, A. and Merdes, A. and Gervais, V.

NMR secondary structure and interactions of recombinant human MOZART1 protein, a component of the gamma-tubulin complex

Protein Sci (2017)

26, 2240-2248

10.1002/pro.3282

Da Silva, F. and Desaphy, J. and Bret, G. and Rognan, D.

IChemPIC: A Random Forest Classifier of Biological and Crystallographic Protein-Protein Interfaces

J Chem Inf Model (2015)

55, 2005-14

10.1021/acs.jcim.5b00190

Da Silva, F. and Desaphy, J. and Rognan, D.

IChem: A Versatile Toolkit for Detecting, Comparing, and Predicting Protein-Ligand Interactions

ChemMedChem (2018)

13, 507-510

10.1002/cmdc.201700505

da Silva Figueiredo Celestino Gomes, P. and Da Silva, F. and Bret, G. and Rognan, D.

Ranking docking poses by graph matching of protein-ligand interactions: lessons learned from the D3R Grand Challenge 2

J Comput Aided Mol Des (2018)

32, 75-87

10.1007/s10822-017-0046-1

Dabo, S. and Maillard, P. and Collados Rodriguez, M. and Hansen, M. D. and Mazouz, S. and Bigot, D. J. and Tible, M. and Janvier, G. and Helynck, O. and Cassonnet, P. and Jacob, Y. and Bellalou, J. and Gatignol, A. and Patel, R. C. and Hugon, J. and Munier-Lehmann, H. and Meurs, E. F.

Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT

Sci Rep (2017)

7, 16129

10.1038/s41598-017-16089-8

Dago, C. D. and Ambeu, C. N. and Coulibaly, W. K. and Bekro, Y. A. and Mamyrbekova, J. and Defontaine, A. and Baratte, B. and Bach, S. and Ruchaud, S. and Guevel, R. L. and Ravache, M. and Corlu, A. and Bazureau, J. P.

Synthetic Development of New 3-(4-Arylmethylamino)butyl-5-arylidene-rhodanines under Microwave Irradiation and Their Effects on Tumor Cell Lines and against Protein Kinases

Molecules (2015)

20, 12412-35

10.3390/molecules200712412

Dai, W. and Wu, Y. and Bi, J. and Lu, X. and Hou, A. and Zhou, Y. and Sun, B. and Kong, W. and Barbier, J. and Cintrat, J. C. and Gao, F. and Gillet, D. and Su, W. and Jiang, C.

Antiviral effects of Retro-2(cycl) and Retro-2.1 against Enterovirus 71 in vitro and in vivo

Antiviral Res (2017)

144, 311-321

10.1016/j.antiviral.2017.07.001

Dai, W. and Wu, Y. and Bi, J. and Wang, J. and Wang, S. and Kong, W. and Barbier, J. and Cintrat, J. C. and Gao, F. and Jiang, Z. and Gillet, D. and Su, W. and Jiang, C.

Antiviral Effect of Retro-2.1 against Herpes Simplex Virus Type 2 In Vitro

J Microbiol Biotechnol (2018)

28, 849-859

10.4014/jmb.1712.12052

Dai, W. and Wu, Y. and Bi, J. and Wang, S. and Li, F. and Kong, W. and Barbier, J. and Cintrat, J. C. and Gao, F. and Gillet, D. and Su, W. and Jiang, C.

Antiviral Effects of ABMA against Herpes Simplex Virus Type 2 In Vitro and In Vivo

Viruses (2018)

10,

10.3390/v10030119

Dalton, J. A. R. and Pin, J. P. and Giraldo, J.

Analysis of positive and negative allosteric modulation in metabotropic glutamate receptors 4 and 5 with a dual ligand

Sci Rep (2017)

7, 4944

10.1038/s41598-017-05095-5

Dannhoffer, L. and Billet, A. and Jollivet, M. and Melin-Heschel, P. and Faveau, C. and Becq, F.

Stimulation of Wild-Type, F508del- and G551D-CFTR Chloride Channels by Non-Toxic Modified pyrrolo[2,3-b]pyrazine Derivatives

Front Pharmacol (2011)

2, 48

10.3389/fphar.2011.00048

Dao, V. H. and Ourliac-Garnier, I. and Bazin, M. A. and Jacquot, C. and Baratte, B. and Ruchaud, S. and Bach, S. and Grovel, O. and Le Pape, P. and Marchand, P.

Benzofuro[3,2-d]pyrimidines inspired from cercosporamide CaPkc1 inhibitor: Synthesis and evaluation of fluconazole susceptibility restoration

Bioorg Med Chem Lett (2018)

28, 2250-2255

10.1016/j.bmcl.2018.05.044

Darvishi, F. and Moradi, M. and Madzak, C. and Jolivalt, C.

Production of Laccase by Recombinant Yarrowia lipolytica from Molasses: Bioprocess Development Using Statistical Modeling and Increase Productivity in Shake-Flask and Bioreactor Cultures

Appl Biochem Biotechnol (2017)

181, 1228-1239

10.1007/s12010-016-2280-8

Daskalogianni, C. and Pyndiah, S. and Apcher, S. and Mazars, A. and Manoury, B. and Ammari, N. and Nylander, K. and Voisset, C. and Blondel, M. and Fahraeus, R.

Epstein-Barr virus-encoded EBNA1 and ZEBRA: targets for therapeutic strategies against EBV-carrying cancers

J Pathol (2015)

235, 334-41

10.1002/path.4431

Daubeuf, F. and Hachet-Haas, M. and Gizzi, P. and Gasparik, V. and Bonnet, D. and Utard, V. and Hibert, M. and Frossard, N. and Galzi, J. L.

An antedrug of the CXCL12 neutraligand blocks experimental allergic asthma without systemic effect in mice

J Biol Chem (2013)

288, 11865-76

10.1074/jbc.M112.449348

Daval, S. B. and Kellenberger, E. and Bonnet, D. and Utard, V. and Galzi, J. L. and Ilien, B.

Exploration of the orthosteric/allosteric interface in human M1 muscarinic receptors by bitopic fluorescent ligands

Mol Pharmacol (2013)

84, 71-85

10.1124/mol.113.085670

Daval, S. B. and Valant, C. and Bonnet, D. and Kellenberger, E. and Hibert, M. and Galzi, J. L. and Ilien, B.

Fluorescent derivatives of AC-42 to probe bitopic orthosteric/allosteric binding mechanisms on muscarinic M1 receptors

J Med Chem (2012)

55, 2125-43

10.1021/jm201348t

Delava, E. and Fleury, F. and Gibert, P.

Effects of daily fluctuating temperatures on the Drosophila-Leptopilina boulardi parasitoid association

J Therm Biol (2016)

60, 95-102

10.1016/j.jtherbio.2016.06.012

Delay-Goyet, P. and Blanchard, V. and Schussler, N. and Lopez-Grancha, M. and Menager, J. and Mary, V. and Sultan, E. and Buzy, A. and Guillemot, J. C. and Stemmelin, J. and Bertrand, P. and Rooney, T. and Pradier, L. and Barneoud, P.

SAR110894, a potent histamine H3-receptor antagonist, displays disease-modifying activity in a transgenic mouse model of tauopathy

Alzheimers Dement (N Y) (2016)

2, 267-280

10.1016/j.trci.2016.10.002

Delbeke, E. I. and Lozach, O. and Le Gall, T. and Berchel, M. and Montier, T. and Jaffres, P. A. and Van Geem, K. M. and Stevens, C. V.

Evaluation of the transfection efficacies of quaternary ammonium salts prepared from sophorolipids

Org Biomol Chem (2016)

14, 3744-51

10.1039/c6ob00241b

Delcourt, N. and Quevedo, C. and Nonne, C. and Fons, P. and O'Brien, D. and Loyaux, D. and Diez, M. and Autelitano, F. and Guillemot, J. C. and Ferrara, P. and Muriana, A. and Callol, C. and Herault, J. P. and Herbert, J. M. and Favre, G. and Bono, F.

Targeted identification of sialoglycoproteins in hypoxic endothelial cells and validation in zebrafish reveal roles for proteins in angiogenesis

J Biol Chem (2015)

290, 3405-17

10.1074/jbc.M114.618611

Delehouze, C. and Leverrier-Penna, S. and Le Cann, F. and Comte, A. and Jacquard-Fevai, M. and Delalande, O. and Desban, N. and Baratte, B. and Gallais, I. and Faurez, F. and Bonnet, M. C. and Hauteville, M. and Goekjian, P. G. and Thuillier, R. and Favreau, F. and Vandenabeele, P. and Hauet, T. and Dimanche-Boitrel, M. T. and Bach, S.

6E11, a highly selective inhibitor of Receptor-Interacting Protein Kinase 1, protects cells against cold hypoxia-reoxygenation injury

Sci Rep (2017)

7, 12931

10.1038/s41598-017-12788-4

Delfosse, V. and Grimaldi, M. and Pons, J. L. and Boulahtouf, A. and le Maire, A. and Cavailles, V. and Labesse, G. and Bourguet, W. and Balaguer, P.

Structural and mechanistic insights into bisphenols action provide guidelines for risk assessment and discovery of bisphenol A substitutes

Proc Natl Acad Sci U S A (2012)

109, 14930-5

10.1073/pnas.1203574109

Delorme, V. and Song, O. R. and Baulard, A. and Brodin, P.

Testing chemical and genetic Modulators in Mycobacterium tuberculosis infected cells using phenotypic assays

Methods Mol Biol (2015)

1285, 387-411

10.1007/978-1-4939-2450-9_24

Demange, L. and Abdellah, F. N. and Lozach, O. and Ferandin, Y. and Gresh, N. and Meijer, L. and Galons, H.

Potent inhibitors of CDK5 derived from roscovitine: synthesis, biological evaluation and molecular modelling

Bioorg Med Chem Lett (2013)

23, 125-31

10.1016/j.bmcl.2012.10.141

Deprez-Poulain, R. and Cousaert, N. and Toto, P. and Willand, N. and Deprez, B.

Application of Ullmann and Ullmann-Finkelstein reactions for the synthesis of N-aryl-N-(1H-pyrazol-3-yl) acetamide or N-(1-aryl-1H-pyrazol-3-yl) acetamide derivatives and pharmacological evaluation

Eur J Med Chem (2011)

46, 3867-76

10.1016/j.ejmech.2011.05.056

Deprez-Poulain, R. and Flipo, M. and Piveteau, C. and Leroux, F. and Dassonneville, S. and Florent, I. and Maes, L. and Cos, P. and Deprez, B.

Structure-activity relationships and blood distribution of antiplasmodial aminopeptidase-1 inhibitors

J Med Chem (2012)

55, 10909-17

10.1021/jm301506h

Deprez-Poulain, R. and Hennuyer, N. and Bosc, D. and Liang, W. G. and Enee, E. and Marechal, X. and Charton, J. and Totobenazara, J. and Berte, G. and Jahklal, J. and Verdelet, T. and Dumont, J. and Dassonneville, S. and Woitrain, E. and Gauriot, M. and Paquet, C. and Duplan, I. and Hermant, P. and Cantrelle, F. X. and Sevin, E. and Culot, M. and Landry, V. and Herledan, A. and Piveteau, C. and Lippens, G. and Leroux, F. and Tang, W. J. and van Endert, P. and Staels, B. and Deprez, B.

Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice

Nat Commun (2015)

6, 8250

10.1038/ncomms9250

Desaphy, J. and Azdimousa, K. and Kellenberger, E. and Rognan, D.

Comparison and druggability prediction of protein-ligand binding sites from pharmacophore-annotated cavity shapes

J Chem Inf Model (2012)

52, 2287-99

10.1021/ci300184x

Desaphy, J. and Bret, G. and Rognan, D. and Kellenberger, E.

sc-PDB: a 3D-database of ligandable binding sites--10 years on

Nucleic Acids Res (2015)

43, D399-404

10.1093/nar/gku928

Desaphy, J. and Raimbaud, E. and Ducrot, P. and Rognan, D.

Encoding protein-ligand interaction patterns in fingerprints and graphs

J Chem Inf Model (2013)

53, 623-37

10.1021/ci300566n

Desaphy, J. and Rognan, D.

sc-PDB-Frag: a database of protein-ligand interaction patterns for Bioisosteric replacements

J Chem Inf Model (2014)

54, 1908-18

10.1021/ci500282c

Galani, B. R. and Sahuc, M. E. and Njayou, F. N. and Deloison, G. and Mkounga, P. and Feudjou, W. F. and Brodin, P. and Rouille, Y. and Nkengfack, A. E. and Moundipa, P. F. and Seron, K.

Plant extracts from Cameroonian medicinal plants strongly inhibit hepatitis C virus infection in vitro

Front Microbiol (2015)

6, 488

10.3389/fmicb.2015.00488

Galani, B. R. and Sahuc, M. E. and Sass, G. and Njayou, F. N. and Loscher, C. and Mkounga, P. and Deloison, G. and Brodin, P. and Rouille, Y. and Tiegs, G. and Seron, K. and Moundipa, P. F.

Khaya grandifoliola C.DC: a potential source of active ingredients against hepatitis C virus in vitro

Arch Virol (2016)

161, 1169-81

10.1007/s00705-016-2771-5

Galluzzi, L. and Bravo-San Pedro, J. M. and Vitale, I. and Aaronson, S. A. and Abrams, J. M. and Adam, D. and Alnemri, E. S. and Altucci, L. and Andrews, D. and Annicchiarico-Petruzzelli, M. and Baehrecke, E. H. and Bazan, N. G. and Bertrand, M. J. and Bianchi, K. and Blagosklonny, M. V. and Blomgren, K. and Borner, C. and Bredesen, D. E. and Brenner, C. and Campanella, M. and Candi, E. and Cecconi, F. and Chan, F. K. and Chandel, N. S. and Cheng, E. H. and Chipuk, J. E. and Cidlowski, J. A. and Ciechanover, A. and Dawson, T. M. and Dawson, V. L. and De Laurenzi, V. and De Maria, R. and Debatin, K. M. and Di Daniele, N. and Dixit, V. M. and Dynlacht, B. D. and El-Deiry, W. S. and Fimia, G. M. and Flavell, R. A. and Fulda, S. and Garrido, C. and Gougeon, M. L. and Green, D. R. and Gronemeyer, H. and Hajnoczky, G. and Hardwick, J. M. and Hengartner, M. O. and Ichijo, H. and Joseph, B. and Jost, P. J. and Kaufmann, T. and Kepp, O. and Klionsky, D. J. and Knight, R. A. and Kumar, S. and Lemasters, J. J. and Levine, B. and Linkermann, A. and Lipton, S. A. and Lockshin, R. A. and Lopez-Otin, C. and Lugli, E. and Madeo, F. and Malorni, W. and Marine, J. C. and Martin, S. J. and Martinou, J. C. and Medema, J. P. and Meier, P. and Melino, S. and Mizushima, N. and Moll, U. and Munoz-Pinedo, C. and Nunez, G. and Oberst, A. and Panaretakis, T. and Penninger, J. M. and Peter, M. E. and Piacentini, M. and Pinton, P. and Prehn, J. H. and Puthalakath, H. and Rabinovich, G. A. and Ravichandran, K. S. and Rizzuto, R. and Rodrigues, C. M. and Rubinsztein, D. C. and Rudel, T. and Shi, Y. and Simon, H. U. and Stockwell, B. R. and Szabadkai, G. and Tait, S. W. and Tang, H. L. and Tavernarakis, N. and Tsujimoto, Y. and Vanden Berghe, T. and Vandenabeele, P. and Villunger, A. and Wagner, E. F. and others

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

Cell Death Differ (2015)

22, 58-73

10.1038/cdd.2014.137

Galluzzi, L. and Vitale, I. and Aaronson, S. A. and Abrams, J. M. and Adam, D. and Agostinis, P. and Alnemri, E. S. and Altucci, L. and Amelio, I. and Andrews, D. W. and Annicchiarico-Petruzzelli, M. and Antonov, A. V. and Arama, E. and Baehrecke, E. H. and Barlev, N. A. and Bazan, N. G. and Bernassola, F. and Bertrand, M. J. M. and Bianchi, K. and Blagosklonny, M. V. and Blomgren, K. and Borner, C. and Boya, P. and Brenner, C. and Campanella, M. and Candi, E. and Carmona-Gutierrez, D. and Cecconi, F. and Chan, F. K. and Chandel, N. S. and Cheng, E. H. and Chipuk, J. E. and Cidlowski, J. A. and Ciechanover, A. and Cohen, G. M. and Conrad, M. and Cubillos-Ruiz, J. R. and Czabotar, P. E. and D'Angiolella, V. and Dawson, T. M. and Dawson, V. L. and De Laurenzi, V. and De Maria, R. and Debatin, K. M. and DeBerardinis, R. J. and Deshmukh, M. and Di Daniele, N. and Di Virgilio, F. and Dixit, V. M. and Dixon, S. J. and Duckett, C. S. and Dynlacht, B. D. and El-Deiry, W. S. and Elrod, J. W. and Fimia, G. M. and Fulda, S. and Garcia-Saez, A. J. and Garg, A. D. and Garrido, C. and Gavathiotis, E. and Golstein, P. and Gottlieb, E. and Green, D. R. and Greene, L. A. and Gronemeyer, H. and Gross, A. and Hajnoczky, G. and Hardwick, J. M. and Harris, I. S. and Hengartner, M. O. and Hetz, C. and Ichijo, H. and Jaattela, M. and Joseph, B. and Jost, P. J. and Juin, P. P. and Kaiser, W. J. and Karin, M. and Kaufmann, T. and Kepp, O. and Kimchi, A. and Kitsis, R. N. and Klionsky, D. J. and Knight, R. A. and Kumar, S. and Lee, S. W. and Lemasters, J. J. and Levine, B. and Linkermann, A. and Lipton, S. A. and Lockshin, R. A. and Lopez-Otin, C. and Lowe, S. W. and Luedde, T. and Lugli, E. and MacFarlane, M. and Madeo, F. and Malewicz, M. and Malorni, W. and Manic, G. and others

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

Cell Death Differ (2018)

25, 486-541

10.1038/s41418-017-0012-4

Galluzzi, L. and Vitale, I. and Michels, J. and Brenner, C. and Szabadkai, G. and Harel-Bellan, A. and Castedo, M. and Kroemer, G.

Systems biology of cisplatin resistance: past, present and future

Cell Death Dis (2014)

5, e1257

10.1038/cddis.2013.428

Gally, J. M. and Bourg, S. and Do, Q. T. and Aci-Seche, S. and Bonnet, P.

VSPrep: A General KNIME Workflow for the Preparation of Molecules for Virtual Screening

Mol Inform (2017)

36,

10.1002/minf.201700023

Galvani, G. and Vardhan Reddy, K. H. and Beauvineau, C. and Ghermani, N. and Mahuteau-Betzer, F. and Alami, M. and Messaoudi, S.

Conversion of 3-Bromo-2H-coumarins to 3-(Benzofuran-2-yl)-2H-coumarins under Palladium Catalysis: Synthesis and Photophysical Properties Study

Org Lett (2017)

19, 910-913

10.1021/acs.orglett.7b00069

Deshiere, A. and Duchemin-Pelletier, E. and Spreux, E. and Ciais, D. and Combes, F. and Vandenbrouck, Y. and Coute, Y. and Mikaelian, I. and Giusiano, S. and Charpin, C. and Cochet, C. and Filhol, O.

Unbalanced expression of CK2 kinase subunits is sufficient to drive epithelial-to-mesenchymal transition by Snail1 induction

Oncogene (2013)

32, 1373-83

10.1038/onc.2012.165

Deshiere, A. and Duchemin-Pelletier, E. and Spreux, E. and Ciais, D. and Forcet, C. and Cochet, C. and Filhol, O.

Regulation of epithelial to mesenchymal transition: CK2beta on stage

Mol Cell Biochem (2011)

356, 11-20

10.1007/s11010-011-0942-y

Desire, J. and Mondon, M. and Fontelle, N. and Nakagawa, S. and Hirokami, Y. and Adachi, I. and Iwaki, R. and Fleet, G. W. and Alonzi, D. S. and Twigg, G. and Butters, T. D. and Bertrand, J. and Cendret, V. and Becq, F. and Norez, C. and Marrot, J. and Kato, A. and Bleriot, Y.

N- and C-alkylation of seven-membered iminosugars generates potent glucocerebrosidase inhibitors and F508del-CFTR correctors

Org Biomol Chem (2014)

12, 8977-96

10.1039/c4ob00325j

Desrat, S. and Pujals, A. and Colas, C. and Dardenne, J. and Geny, C. and Favre, L. and Dumontet, V. and Iorga, B. I. and Litaudon, M. and Raphael, M. and Wiels, J. and Roussi, F.

Pro-apoptotic meiogynin A derivatives that target Bcl-xL and Mcl-1

Bioorg Med Chem Lett (2014)

24, 5086-8

10.1016/j.bmcl.2014.09.004

Desrat, S. and Remeur, C. and Geny, C. and Riviere, G. and Colas, C. and Dumontet, V. and Birlirakis, N. and Iorga, B. I. and Roussi, F.

From meiogynin A to the synthesis of dual inhibitors of Bcl-xL and Mcl-1 anti-apoptotic proteins

Chem Commun (Camb) (2014)

50, 8593-6

10.1039/c4cc01830c

Desroches-Castan, A. and Quelard, D. and Demeunynck, M. and Constant, J. F. and Dong, C. and Keramidas, M. and Coll, J. L. and Barette, C. and Lafanechere, L. and Feige, J. J.

A new chemical inhibitor of angiogenesis and tumorigenesis that targets the VEGF signaling pathway upstream of Ras

Oncotarget (2015)

6, 5382-411

10.18632/oncotarget.2979

Devailly, G. and Grandin, M. and Perriaud, L. and Mathot, P. and Delcros, J. G. and Bidet, Y. and Morel, A. P. and Bignon, J. Y. and Puisieux, A. and Mehlen, P. and Dante, R.

Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells

Nucleic Acids Res (2015)

43, 5838-54

10.1093/nar/gkv508

Devert, A. and Fabre, N. and Floris, M. and Canard, B. and Robaglia, C. and Crete, P.

Primer-dependent and primer-independent initiation of double stranded RNA synthesis by purified Arabidopsis RNA-dependent RNA polymerases RDR2 and RDR6

PLoS One (2015)

10, e0120100

10.1371/journal.pone.0120100

Di Michele, M. and Stes, E. and Vandermarliere, E. and Arora, R. and Astorga-Wells, J. and Vandenbussche, J. and van Heerde, E. and Zubarev, R. and Bonnet, P. and Linders, J. T. and Jacoby, E. and Brehmer, D. and Martens, L. and Gevaert, K.

Limited Proteolysis Combined with Stable Isotope Labeling Reveals Conformational Changes in Protein (Pseudo)kinases upon Binding Small Molecules

J Proteome Res (2015)

14, 4179-93

10.1021/acs.jproteome.5b00282

Dibenedetto, S. and Cluet, D. and Stebe, P. N. and Baumle, V. and Leault, J. and Terreux, R. and Bickle, M. and Chassey, B. D. and Mikaelian, I. and Colas, P. and Spichty, M. and Zoli, M. and Rudkin, B. B.

Calcineurin A versus NS5A-TP2/HD domain containing 2: a case study of site-directed low-frequency random mutagenesis for dissecting target specificity of peptide aptamers

Mol Cell Proteomics (2013)

12, 1939-52

10.1074/mcp.M112.024612

Diguet, N. and Trammell, S. A. J. and Tannous, C. and Deloux, R. and Piquereau, J. and Mougenot, N. and Gouge, A. and Gressette, M. and Manoury, B. and Blanc, J. and Breton, M. and Decaux, J. F. and Lavery, G. G. and Baczko, I. and Zoll, J. and Garnier, A. and Li, Z. and Brenner, C. and Mericskay, M.

Nicotinamide Riboside Preserves Cardiac Function in a Mouse Model of Dilated Cardiomyopathy

Circulation (2018)

137, 2256-2273

10.1161/CIRCULATIONAHA.116.026099

Dinarvand, P. and Yang, L. and Villoutreix, B. O. and Rezaie, A. R.

Expression and functional characterization of two natural heparin-binding site variants of antithrombin

J Thromb Haemost (2018)

16, 330-341

10.1111/jth.13920

Dion, J. and Advedissian, T. and Storozhylova, N. and Dahbi, S. and Lambert, A. and Deshayes, F. and Viguier, M. and Tellier, C. and Poirier, F. and Teletchea, S. and Dussouy, C. and Tateno, H. and Hirabayashi, J. and Grandjean, C.

Development of a Sensitive Microarray Platform for the Ranking of Galectin Inhibitors: Identification of a Selective Galectin-3 Inhibitor

Chembiochem (2017)

18, 2428-2440

10.1002/cbic.201700544

Dion, J. and Deshayes, F. and Storozhylova, N. and Advedissian, T. and Lambert, A. and Viguier, M. and Tellier, C. and Dussouy, C. and Poirier, F. and Grandjean, C.

Lactosamine-Based Derivatives as Tools to Delineate the Biological Functions of Galectins: Application to Skin Tissue Repair

Chembiochem (2017)

18, 782-789

10.1002/cbic.201600673

Dirami, T. and Rode, B. and Jollivet, M. and Da Silva, N. and Escalier, D. and Gaitch, N. and Norez, C. and Tuffery, P. and Wolf, J. P. and Becq, F. and Ray, P. F. and Dulioust, E. and Gacon, G. and Bienvenu, T. and Toure, A.

Missense mutations in SLC26A8, encoding a sperm-specific activator of CFTR, are associated with human asthenozoospermia

Am J Hum Genet (2013)

92, 760-6

10.1016/j.ajhg.2013.03.016

Djehal, A. and Krayem, M. and Najem, A. and Hammoud, H. and Cresteil, T. and Nebigil, C. G. and Wang, D. and Yu, P. and Bentouhami, E. and Ghanem, G. E. and Desaubry, L.

Targeting prohibitin with small molecules to promote melanogenesis and apoptosis in melanoma cells

Eur J Med Chem (2018)

155, 880-888

10.1016/j.ejmech.2018.06.052

Do, C. V. and Faouzi, A. and Barette, C. and Farce, A. and Fauvarque, M. O. and Colomb, E. and Catry, L. and Berthier-Vergnes, O. and Haftek, M. and Barret, R. and Lomberget, T.

Synthesis and biological evaluation of thiophene and benzo[b]thiophene analogs of combretastatin A-4 and isocombretastatin A-4: A comparison between the linkage positions of the 3,4,5-trimethoxystyrene unit

Bioorg Med Chem Lett (2016)

26, 174-80

10.1016/j.bmcl.2015.11.010

Doebelin, C. and Bertin, I. and Schneider, S. and Schmitt, M. and Bourguignon, J. J. and Ancel, C. and Simonneaux, V. and Simonin, F. and Bihel, F.

Development of Dipeptidic hGPR54 Agonists

ChemMedChem (2016)

11, 2147-2154

10.1002/cmdc.201600331

Dong, J. and Aulestia, F. J. and Assad Kahn, S. and Zeniou, M. and Dubois, L. G. and El-Habr, E. A. and Daubeuf, F. and Tounsi, N. and Cheshier, S. H. and Frossard, N. and Junier, M. P. and Chneiweiss, H. and Neant, I. and Moreau, M. and Leclerc, C. and Haiech, J. and Kilhoffer, M. C.

Bisacodyl and its cytotoxic activity on human glioblastoma stem-like cells. Implication of inositol 1,4,5-triphosphate receptor dependent calcium signaling

Biochim Biophys Acta (2017)

1864, 1018-1027

10.1016/j.bbamcr.2017.01.010

Dovgan, I. and Erb, S. and Hessmann, S. and Ursuegui, S. and Michel, C. and Muller, C. and Chaubet, G. and Cianferani, S. and Wagner, A.

Arginine-selective bioconjugation with 4-azidophenyl glyoxal: application to the single and dual functionalisation of native antibodies

Org Biomol Chem (2018)

16, 1305-1311

10.1039/c7ob02844j

Dovgan, I. and Kolodych, S. and Koniev, O. and Wagner, A.

2-(Maleimidomethyl)-1,3-Dioxanes (MD): a Serum-Stable Self-hydrolysable Hydrophilic Alternative to Classical Maleimide Conjugation

Sci Rep (2016)

6, 30835

10.1038/srep30835

Dovgan, I. and Ursuegui, S. and Erb, S. and Michel, C. and Kolodych, S. and Cianferani, S. and Wagner, A.

Acyl Fluorides: Fast, Efficient, and Versatile Lysine-Based Protein Conjugation via Plug-and-Play Strategy

Bioconjug Chem (2017)

28, 1452-1457

10.1021/acs.bioconjchem.7b00141

Drieu la Rochelle, A. and Guillemyn, K. and Dumitrascuta, M. and Martin, C. and Utard, V. and Quillet, R. and Schneider, S. and Daubeuf, F. and Willemse, T. and Mampuys, P. and Maes, B. U. W. and Frossard, N. and Bihel, F. and Spetea, M. and Simonin, F. and Ballet, S.

A bifunctional-biased mu-opioid agonist-neuropeptide FF receptor antagonist as analgesic with improved acute and chronic side effects

Pain (2018)

,

10.1097/j.pain.0000000000001262

Duchemin-Pelletier, E. and Baulard, M. and Spreux, E. and Prioux, M. and Burute, M. and Mograbi, B. and Guyon, L. and Thery, M. and Cochet, C. and Filhol, O.

Stem Cell-Like Properties of CK2beta-down Regulated Mammary Cells

Cancers (Basel) (2017)

9,

10.3390/cancers9090114

Dumont, J. and Goumidi, L. and Grenier-Boley, B. and Cottel, D. and Marecaux, N. and Montaye, M. and Wagner, A. and Arveiler, D. and Simon, C. and Ferrieres, J. and Ruidavets, J. B. and Amouyel, P. and Dallongeville, J. and Meirhaeghe, A.

Dietary linoleic acid interacts with FADS1 genetic variability to modulate HDL-cholesterol and obesity-related traits

Clin Nutr (2017)

,

10.1016/j.clnu.2017.07.012

Duquenne, C. and Gimenez, S. and Guigues, A. and Viala, B. and Boulouis, C. and Mettling, C. and Maurel, D. and Campos, N. and Doumazane, E. and Comps-Agrar, L. and Tazi, J. and Prezeau, L. and Psomas, C. and Corbeau, P. and Francois, V.

Reversing HIV latency via sphingosine-1-phosphate receptor 1 signaling

AIDS (2017)

31, 2443-2454

10.1097/QAD.0000000000001649

Durieu, E. and Prina, E. and Leclercq, O. and Oumata, N. and Gaboriaud-Kolar, N. and Vougogiannopoulou, K. and Aulner, N. and Defontaine, A. and No, J. H. and Ruchaud, S. and Skaltsounis, A. L. and Galons, H. and Spath, G. F. and Meijer, L. and Rachidi, N.

From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity

Antimicrob Agents Chemother (2016)

60, 2822-33

10.1128/AAC.00021-16

Duris, A. and Daich, A. and Santos, C. and Fleury, L. and Ausseil, F. and Rodriguez, F. and Ballereau, S. and Genisson, Y. and Berkes, D.

Asymmetric Synthesis and Binding Study of New Long-Chain HPA-12 Analogues as Potent Ligands of the Ceramide Transfer Protein CERT

Chemistry (2016)

22, 6676-86

10.1002/chem.201505121

Duruisseaux, M. and Antoine, M. and Rabbe, N. and Poulot, V. and Fleury-Feith, J. and Vieira, T. and Lavole, A. and Cadranel, J. and Wislez, M.

The impact of intracytoplasmic mucin in lung adenocarcinoma with pneumonic radiological presentation

Lung Cancer (2014)

83, 334-40

10.1016/j.lungcan.2013.12.016

Egorov, M. and Delpech, B. and Aubert, G. and Cresteil, T. and Garcia-Alvarez, M. C. and Collin, P. and Marazano, C.

A concise formation of N-substituted 3,4-diarylpyrroles--synthesis and cytotoxic activity

Org Biomol Chem (2014)

12, 1518-24

10.1039/c3ob42309c

Eisenberger, M. and Hardy-Bessard, A. C. and Kim, C. S. and Geczi, L. and Ford, D. and Mourey, L. and Carles, J. and Parente, P. and Font, A. and Kacso, G. and Chadjaa, M. and Zhang, W. and Bernard, J. and de Bono, J.

Phase III Study Comparing a Reduced Dose of Cabazitaxel (20 mg/m(2)) and the Currently Approved Dose (25 mg/m(2)) in Postdocetaxel Patients With Metastatic Castration-Resistant Prostate Cancer-PROSELICA

J Clin Oncol (2017)

35, 3198-3206

10.1200/JCO.2016.72.1076

El Arfaoui, D. and Listunov, D. and Fabing, I. and Oukessou, M. and Frongia, C. and Lobjois, V. and Samson, A. and Ausseil, F. and Ben-Tama, A. and El Hadrami el, M. and Chauvin, R. and Genisson, Y.

Identification of chiral alkenyl- and alkynylcarbinols as pharmacophores for potent cytotoxicity

ChemMedChem (2013)

8, 1779-86

10.1002/cmdc.201300230

El Bakali, J. and Gras-Masse, H. and Maingot, L. and Deprez, B. and Dumont, J. and Leroux, F. and Deprez-Poulain, R.

Inhibition of aggrecanases as a therapeutic strategy in osteoarthritis

Future Med Chem (2014)

6, 1399-412

10.4155/fmc.14.84

El Brahmi, N. and Mignani, S. M. and Caron, J. and El Kazzouli, S. and Bousmina, M. M. and Caminade, A. M. and Cresteil, T. and Majoral, J. P.

Investigations on dendrimer space reveal solid and liquid tumor growth-inhibition by original phosphorus-based dendrimers and the corresponding monomers and dendrons with ethacrynic acid motifs

Nanoscale (2015)

7, 3915-22

10.1039/c4nr05983b

El Chemaly, A. and Norez, C. and Magaud, C. and Bescond, J. and Chatelier, A. and Fares, N. and Findlay, I. and Jayle, C. and Becq, F. and Faivre, J. F. and Bois, P.

ANO1 contributes to angiotensin-II-activated Ca2+-dependent Cl- current in human atrial fibroblasts

J Mol Cell Cardiol (2014)

68, 12-9

10.1016/j.yjmcc.2013.12.027

El-Seedy, A. and Girodon, E. and Norez, C. and Pajaud, J. and Pasquet, M. C. and de Becdelievre, A. and Bienvenu, T. and des Georges, M. and Cabet, F. and Lalau, G. and Bieth, E. and Blayau, M. and Becq, F. and Kitzis, A. and Fanen, P. and Ladeveze, V.

CFTR mutation combinations producing frequent complex alleles with different clinical and functional outcomes

Hum Mutat (2012)

33, 1557-65

10.1002/humu.22129

Elhabazi, K. and Humbert, J. P. and Bertin, I. and Quillet, R. and Utard, V. and Schneider, S. and Schmitt, M. and Bourguignon, J. J. and Laboureyras, E. and Ben Boujema, M. and Simonnet, G. and Ancel, C. and Simonneaux, V. and Beltramo, M. and Bucher, B. and Sorg, T. and Meziane, H. and Schneider, E. and Petit-Demouliere, B. and Ilien, B. and Bihel, F. and Simonin, F.

RF313, an orally bioavailable neuropeptide FF receptor antagonist, opposes effects of RF-amide-related peptide-3 and opioid-induced hyperalgesia in rodents

Neuropharmacology (2017)

118, 188-198

10.1016/j.neuropharm.2017.03.012

Elhabazi, K. and Humbert, J. P. and Bertin, I. and Schmitt, M. and Bihel, F. and Bourguignon, J. J. and Bucher, B. and Becker, J. A. and Sorg, T. and Meziane, H. and Petit-Demouliere, B. and Ilien, B. and Simonin, F.

Endogenous mammalian RF-amide peptides, including PrRP, kisspeptin and 26RFa, modulate nociception and morphine analgesia via NPFF receptors

Neuropharmacology (2013)

75, 164-71

10.1016/j.neuropharm.2013.07.012

Elhabazi, K. and Trigo, J. M. and Mollereau, C. and Mouledous, L. and Zajac, J. M. and Bihel, F. and Schmitt, M. and Bourguignon, J. J. and Meziane, H. and Petit-demouliere, B. and Bockel, F. and Maldonado, R. and Simonin, F.

Involvement of neuropeptide FF receptors in neuroadaptive responses to acute and chronic opiate treatments

Br J Pharmacol (2012)

165, 424-35

10.1111/j.1476-5381.2011.01563.x

Elhabiri, M. and Sidorov, P. and Cesar-Rodo, E. and Marcou, G. and Lanfranchi, D. A. and Davioud-Charvet, E. and Horvath, D. and Varnek, A.

Electrochemical properties of substituted 2-methyl-1,4-naphthoquinones: redox behavior predictions

Chemistry (2015)

21, 3415-24

10.1002/chem.201403703

Elkaim, J. and Lamblin, M. and Laguerre, M. and Rosenbaum, J. and Lestienne, P. and Eloy, L. and Cresteil, T. and Felpin, F. X. and Dessolin, J.

Design, synthesis and biological evaluation of Pontin ATPase inhibitors through a molecular docking approach

Bioorg Med Chem Lett (2014)

24, 2512-6

10.1016/j.bmcl.2014.04.003

Eloy, L. and Jarrousse, A. S. and Teyssot, M. L. and Gautier, A. and Morel, L. and Jolivalt, C. and Cresteil, T. and Roland, S.

Anticancer activity of silver-N-heterocyclic carbene complexes: caspase-independent induction of apoptosis via mitochondrial apoptosis-inducing factor (AIF)

ChemMedChem (2012)

7, 805-14

10.1002/cmdc.201200055

Erdmann, A. and Menon, Y. and Gros, C. and Masson, V. and Aussagues, Y. and Ausseil, F. and Novosad, N. and Schambel, P. and Baltas, M. and Arimondo, P. B.

Identification and optimization of hydrazone-gallate derivatives as specific inhibitors of DNA methyltransferase 3A

Future Med Chem (2016)

8, 373-80

10.4155/fmc.15.192

Escoll, P. and Song, O. R. and Viana, F. and Steiner, B. and Lagache, T. and Olivo-Marin, J. C. and Impens, F. and Brodin, P. and Hilbi, H. and Buchrieser, C.

Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages

Cell Host Microbe (2017)

22, 302-316 e7

10.1016/j.chom.2017.07.020

Esnault, C. and Renodon-Corniere, A. and Takahashi, M. and Casse, N. and Delorme, N. and Louarn, G. and Fleury, F. and Pilard, J. F. and Chenais, B.

Assessment of DNA binding to human Rad51 protein by using quartz crystal microbalance and atomic force microscopy: effects of ADP and BRC4-28 peptide inhibitor

Chemphyschem (2014)

15, 3753-60

10.1002/cphc.201402451

Eustache, S. and Leprince, J. and Tuffery, P.

Progress with peptide scanning to study structure-activity relationships: the implications for drug discovery

Expert Opin Drug Discov (2016)

11, 771-84

10.1080/17460441.2016.1201058

Evade, L. and Dausse, E. and Taouji, S. and Daguerre, E. and Chevet, E. and Toulme, J. J.

Aptamer-mediated nanoparticle interactions: from oligonucleotide-protein complexes to SELEX screens

Methods Mol Biol (2015)

1297, 153-67

10.1007/978-1-4939-2562-9_11

Faille, A. and Gavalda, S. and Slama, N. and Lherbet, C. and Maveyraud, L. and Guillet, V. and Laval, F. and Quemard, A. and Mourey, L. and Pedelacq, J. D.

Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases

J Mol Biol (2017)

429, 1554-1569

10.1016/j.jmb.2017.03.026

Faklaris, O. and Cottet, M. and Falco, A. and Villier, B. and Laget, M. and Zwier, J. M. and Trinquet, E. and Mouillac, B. and Pin, J. P. and Durroux, T.

Multicolor time-resolved Forster resonance energy transfer microscopy reveals the impact of GPCR oligomerization on internalization processes

FASEB J (2015)

29, 2235-46

10.1096/fj.14-260059

Falke, H. and Chaikuad, A. and Becker, A. and Loaec, N. and Lozach, O. and Abu Jhaisha, S. and Becker, W. and Jones, P. G. and Preu, L. and Baumann, K. and Knapp, S. and Meijer, L. and Kunick, C.

10-iodo-11H-indolo[3,2-c]quinoline-6-carboxylic acids are selective inhibitors of DYRK1A

J Med Chem (2015)

58, 3131-43

10.1021/jm501994d

Farhat, R. and El-Seedy, A. and Sari, A. I. P. and Norez, C. and Pasquet, M. C. and Becq, F. and Kitzis, A. and Ladeveze, V.

In cellulo analyses of the p.Val322Ala mutation on the CFTR protein conformation and activity

C R Biol (2017)

340, 367-371

10.1016/j.crvi.2017.06.001

Faucon, A. and Benhelli-Mokrani, H. and Fleury, F. and Dubreil, L. and Hulin, P. and Nedellec, S. and Doussineau, T. and Antoine, R. and Orlando, T. and Lascialfari, A. and Fresnais, J. and Lartigue, L. and Ishow, E.

Tuning the architectural integrity of high-performance magneto-fluorescent core-shell nanoassemblies in cancer cells

J Colloid Interface Sci (2016)

479, 139-149

10.1016/j.jcis.2016.06.064

Faucon, A. and Benhelli-Mokrani, H. and Fleury, F. and Dutertre, S. and Tramier, M. and Boucard, J. and Lartigue, L. and Nedellec, S. and Hulin, P. and Ishow, E.

Bioconjugated fluorescent organic nanoparticles targeting EGFR-overexpressing cancer cells

Nanoscale (2017)

9, 18094-18106

10.1039/c7nr06533g

Fernandez-Duenas, V. and Taura, J. J. and Cottet, M. and Gomez-Soler, M. and Lopez-Cano, M. and Ledent, C. and Watanabe, M. and Trinquet, E. and Pin, J. P. and Lujan, R. and Durroux, T. and Ciruela, F.

Untangling dopamine-adenosine receptor-receptor assembly in experimental parkinsonism in rats

Dis Model Mech (2015)

8, 57-63

10.1242/dmm.018143

Feron, D. and Charlier, C. and Gourain, V. and Garderet, L. and Coste-Burel, M. and Le Pape, P. and Weigel, P. and Jacques, Y. and Hermouet, S. and Bigot-Corbel, E.

Multiplexed infectious protein microarray immunoassay suitable for the study of the specificity of monoclonal immunoglobulins

Anal Biochem (2013)

433, 202-9

10.1016/j.ab.2012.10.012

Ferron, F. and Subissi, L. and Silveira De Morais, A. T. and Le, N. T. T. and Sevajol, M. and Gluais, L. and Decroly, E. and Vonrhein, C. and Bricogne, G. and Canard, B. and Imbert, I.

Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA

Proc Natl Acad Sci U S A (2018)

115, E162-E171

10.1073/pnas.1718806115

Ferru-Clement, R. and Fresquet, F. and Norez, C. and Metaye, T. and Becq, F. and Kitzis, A. and Thoreau, V.

Involvement of the Cdc42 pathway in CFTR post-translational turnover and in its plasma membrane stability in airway epithelial cells

PLoS One (2015)

10, e0118943

10.1371/journal.pone.0118943

Ferru-Clement, R. and Spanova, M. and Dhayal, S. and Morgan, N. G. and Helye, R. and Becq, F. and Hirose, H. and Antonny, B. and Vamparys, L. and Fuchs, P. F. and Ferreira, T.

Targeting surface voids to counter membrane disorders in lipointoxication-related diseases

J Cell Sci (2016)

129, 2368-81

10.1242/jcs.183590

Feve, M. and Saliou, J. M. and Zeniou, M. and Lennon, S. and Carapito, C. and Dong, J. and Van Dorsselaer, A. and Junier, M. P. and Chneiweiss, H. and Cianferani, S. and Haiech, J. and Kilhoffer, M. C.

Comparative expression study of the endo-G protein coupled receptor (GPCR) repertoire in human glioblastoma cancer stem-like cells, U87-MG cells and non malignant cells of neural origin unveils new potential therapeutic targets

PLoS One (2014)

9, e91519

10.1371/journal.pone.0091519

Filhol, O. and Cochet, C.

Protein kinases curb cell death

Sci Signal (2011)

4, pe26

10.1126/scisignal.2001921

Filhol, O. and Giacosa, S. and Wallez, Y. and Cochet, C.

Protein kinase CK2 in breast cancer: the CK2beta regulatory subunit takes center stage in epithelial plasticity

Cell Mol Life Sci (2015)

72, 3305-22

10.1007/s00018-015-1929-8

Fili, S. and Valmas, A. and Christopoulou, M. and Spiliopoulou, M. and Nikolopoulos, N. and Lichiere, J. and Logotheti, S. and Karavassili, F. and Rosmaraki, E. and Fitch, A. and Wright, J. and Beckers, D. and Degen, T. and Nenert, G. and Hilgenfeld, R. and Papageorgiou, N. and Canard, B. and Coutard, B. and Margiolaki, I.

Coxsackievirus B3 protease 3C: expression, purification, crystallization and preliminary structural insights

Acta Crystallogr F Struct Biol Commun (2016)

72, 877-884

10.1107/S2053230X16018513

Fleury Feith, J. and Jaurand, M. C.

[Pleural lymphatics and pleural diseases related to fibres]

Rev Pneumol Clin (2013)

69, 358-62

10.1016/j.pneumo.2013.09.007

Fleury, L. and Faux, C. and Santos, C. and Ballereau, S. and Genisson, Y. and Ausseil, F.

Development of a CERT START Domain-Ceramide HTRF Binding Assay and Application to Pharmacological Studies and Screening

J Biomol Screen (2015)

20, 779-87

10.1177/1087057115573402

Fleury-Feith, J. and Bernaudin, J. F.

[Cytologic examination in thoracic oncology]

Rev Mal Respir (2011)

28, 254-65

10.1016/j.rmr.2010.12.004

Fleury-Feith, J. and Gounant, V. and Lacave, R. and Cadranel, J. and Bernaudin, J. F.

Multigene mutation analysis on cytologic samples

Chest (2011)

140, 1664

10.1378/chest.11-1238

Flipo, M. and Desroses, M. and Lecat-Guillet, N. and Dirie, B. and Carette, X. and Leroux, F. and Piveteau, C. and Demirkaya, F. and Lens, Z. and Rucktooa, P. and Villeret, V. and Christophe, T. and Jeon, H. K. and Locht, C. and Brodin, P. and Deprez, B. and Baulard, A. R. and Willand, N.

Ethionamide boosters: synthesis, biological activity, and structure-activity relationships of a series of 1,2,4-oxadiazole EthR inhibitors

J Med Chem (2011)

54, 2994-3010

10.1021/jm200076a

Flipo, M. and Desroses, M. and Lecat-Guillet, N. and Villemagne, B. and Blondiaux, N. and Leroux, F. and Piveteau, C. and Mathys, V. and Flament, M. P. and Siepmann, J. and Villeret, V. and Wohlkonig, A. and Wintjens, R. and Soror, S. H. and Christophe, T. and Jeon, H. K. and Locht, C. and Brodin, P. and Deprez, B. and Baulard, A. R. and Willand, N.

Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole EthR inhibitors

J Med Chem (2012)

55, 68-83

10.1021/jm200825u

Flipo, M. and Willand, N. and Lecat-Guillet, N. and Hounsou, C. and Desroses, M. and Leroux, F. and Lens, Z. and Villeret, V. and Wohlkonig, A. and Wintjens, R. and Christophe, T. and Kyoung Jeon, H. and Locht, C. and Brodin, P. and Baulard, A. R. and Deprez, B.

Discovery of novel N-phenylphenoxyacetamide derivatives as EthR inhibitors and ethionamide boosters by combining high-throughput screening and synthesis

J Med Chem (2012)

55, 6391-402

10.1021/jm300377g

Flusin, O. and Saccucci, L. and Contesto-Richefeu, C. and Hamdi, A. and Bardou, C. and Poyot, T. and Peinnequin, A. and Crance, J. M. and Colas, P. and Iseni, F.

A small molecule screen in yeast identifies inhibitors targeting protein-protein interactions within the vaccinia virus replication complex

Antiviral Res (2012)

96, 187-95

10.1016/j.antiviral.2012.07.010

Font, J. and Lopez-Cano, M. and Notartomaso, S. and Scarselli, P. and Di Pietro, P. and Bresoli-Obach, R. and Battaglia, G. and Malhaire, F. and Rovira, X. and Catena, J. and Giraldo, J. and Pin, J. P. and Fernandez-Duenas, V. and Goudet, C. and Nonell, S. and Nicoletti, F. and Llebaria, A. and Ciruela, F.

Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator

Elife (2017)

6,

10.7554/eLife.23545

Fontaine, F. and Hequet, A. and Voisin-Chiret, A. S. and Bouillon, A. and Lesnard, A. and Cresteil, T. and Jolivalt, C. and Rault, S.

First identification of boronic species as novel potential inhibitors of the Staphylococcus aureus NorA efflux pump

J Med Chem (2014)

57, 2536-48

10.1021/jm401808n

Fontaine, F. and Hequet, A. and Voisin-Chiret, A. S. and Bouillon, A. and Lesnard, A. and Cresteil, T. and Jolivalt, C. and Rault, S.

Boronic species as promising inhibitors of the Staphylococcus aureus NorA efflux pump: study of 6-substituted pyridine-3-boronic acid derivatives

Eur J Med Chem (2015)

95, 185-98

10.1016/j.ejmech.2015.02.056

Fourel, L. and Valat, A. and Faurobert, E. and Guillot, R. and Bourrin-Reynard, I. and Ren, K. and Lafanechere, L. and Planus, E. and Picart, C. and Albiges-Rizo, C.

beta3 integrin-mediated spreading induced by matrix-bound BMP-2 controls Smad signaling in a stiffness-independent manner

J Cell Biol (2016)

212, 693-706

10.1083/jcb.201508018

Fournier, N. and Tuloup-Minguez, V. and Pourci, M. L. and Therond, P. and Jullian, J. C. and Wien, F. and Leroy, M. and Dallongeville, J. and Paul, J. L. and Leroy, A.

Fibrate treatment induced quantitative and qualitative HDL changes associated with an increase of SR-BI cholesterol efflux capacities in rabbits

Biochimie (2013)

95, 1278-87

10.1016/j.biochi.2013.02.001

Fox Ramos, A. E. and Alcover, C. and Evanno, L. and Maciuk, A. and Litaudon, M. and Duplais, C. and Bernadat, G. and Gallard, J. F. and Jullian, J. C. and Mouray, E. and Grellier, P. and Loiseau, P. M. and Pomel, S. and Poupon, E. and Champy, P. and Beniddir, M. A.

Revisiting Previously Investigated Plants: A Molecular Networking-Based Study of Geissospermum laeve

J Nat Prod (2017)

80, 1007-1014

10.1021/acs.jnatprod.6b01013

Frantz, M. C. and Rodrigo, J. and Boudier, L. and Durroux, T. and Mouillac, B. and Hibert, M.

Subtlety of the structure-affinity and structure-efficacy relationships around a nonpeptide oxytocin receptor agonist

J Med Chem (2010)

53, 1546-62

10.1021/jm901084f

Freret, T. and Bouet, V. and Quiedeville, A. and Nee, G. and Dallemagne, P. and Rochais, C. and Boulouard, M.

Synergistic effect of acetylcholinesterase inhibition (donepezil) and 5-HT(4) receptor activation (RS67333) on object recognition in mice

Behav Brain Res (2012)

230, 304-8

10.1016/j.bbr.2012.02.012

Fresquet, F. and Clement, R. and Norez, C. and Sterlin, A. and Melin, P. and Becq, F. and Kitzis, A. and Thoreau, V. and Bilan, F.

Orphan missense mutations in the cystic fibrosis transmembrane conductance regulator: A three-step biological approach to establishing a correlation between genotype and phenotype

J Mol Diagn (2011)

13, 520-7

10.1016/j.jmoldx.2011.05.004

Frottin, F. and Bienvenut, W. V. and Bignon, J. and Jacquet, E. and Vaca Jacome, A. S. and Van Dorsselaer, A. and Cianferani, S. and Carapito, C. and Meinnel, T. and Giglione, C.

MetAP1 and MetAP2 drive cell selectivity for a potent anti-cancer agent in synergy, by controlling glutathione redox state

Oncotarget (2016)

7, 63306-63323

10.18632/oncotarget.11216

Furlan, A. and Roux, B. and Lamballe, F. and Conti, F. and Issaly, N. and Daian, F. and Guillemot, J. F. and Richelme, S. and Contensin, M. and Bosch, J. and Passarella, D. and Piccolo, O. and Dono, R. and Maina, F.

Combined drug action of 2-phenylimidazo[2,1-b]benzothiazole derivatives on cancer cells according to their oncogenic molecular signatures

PLoS One (2012)

7, e46738

10.1371/journal.pone.0046738

Gabel, J. and Desaphy, J. and Rognan, D.

Beware of machine learning-based scoring functions-on the danger of developing black boxes

J Chem Inf Model (2014)

54, 2807-15

10.1021/ci500406k

Henninot, A. and Terrier, A. and Charton, J. and Urbain, R. and Fontayne, A. and Deprez, B. and Beghyn, T.

Characterization of monoclonal antibodies by a fast and easy liquid chromatography-mass spectrometry time-of-flight analysis on culture supernatant

Anal Biochem (2015)

491, 52-4

10.1016/j.ab.2015.08.006

Hequet, A. and Burchak, O. N. and Jeanty, M. and Guinchard, X. and Le Pihive, E. and Maigre, L. and Bouhours, P. and Schneider, D. and Maurin, M. and Paris, J. M. and Denis, J. N. and Jolivalt, C.

1-(1H-indol-3-yl)ethanamine derivatives as potent Staphylococcus aureus NorA efflux pump inhibitors

ChemMedChem (2014)

9, 1534-45

10.1002/cmdc.201400042

Hermant, P. and Bosc, D. and Piveteau, C. and Gealageas, R. and Lam, B. and Ronco, C. and Roignant, M. and Tolojanahary, H. and Jean, L. and Renard, P. Y. and Lemdani, M. and Bourotte, M. and Herledan, A. and Bedart, C. and Biela, A. and Leroux, F. and Deprez, B. and Deprez-Poulain, R.

Controlling Plasma Stability of Hydroxamic Acids: A MedChem Toolbox

J Med Chem (2017)

60, 9067-9089

10.1021/acs.jmedchem.7b01444

Hoch, L. and Faure, H. and Roudaut, H. and Schoenfelder, A. and Mann, A. and Girard, N. and Bihannic, L. and Ayrault, O. and Petricci, E. and Taddei, M. and Rognan, D. and Ruat, M.

MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor

FASEB J (2015)

29, 1817-29

10.1096/fj.14-267849

Hoffer, L. and Chira, C. and Marcou, G. and Varnek, A. and Horvath, D.

S4MPLE--Sampler for Multiple Protein-Ligand Entities: Methodology and Rigid-Site Docking Benchmarking

Molecules (2015)

20, 8997-9028

10.3390/molecules20058997

Hoffer, L. and Muller, C. and Roche, P. and Morelli, X.

Chemistry-Driven Hit-To-Lead Optimization Guided by Structure-Based Approaches

Mol Inform (2018)

,

10.1002/minf.201800059

Hoffer, L. and Voitovich, Y. V. and Raux, B. and Carrasco, K. and Muller, C. and Fedorov, A. Y. and Derviaux, C. and Amouric, A. and Betzi, S. and Horvath, D. and Varnek, A. and Collette, Y. and Combes, S. and Roche, P. and Morelli, X.

Integrated Strategy for Lead Optimization Based on Fragment Growing: The Diversity-Oriented-Target-Focused-Synthesis Approach

J Med Chem (2018)

61, 5719-5732

10.1021/acs.jmedchem.8b00653

Hoffmann, E. and Machelart, A. and Song, O. R. and Brodin, P.

Proteomics of Mycobacterium Infection: Moving towards a Better Understanding of Pathogen-Driven Immunomodulation

Front Immunol (2018)

9, 86

10.3389/fimmu.2018.00086

Horvath, D. and Baskin, I. and Marcou, G. and Varnek, A.

Generative Topographic Mapping of Conformational Space

Mol Inform (2017)

36,

10.1002/minf.201700036

Horvath, D. and Koch, C. and Schneider, G. and Marcou, G. and Varnek, A.

Local neighborhood behavior in a combinatorial library context

J Comput Aided Mol Des (2011)

25, 237-52

10.1007/s10822-011-9416-2

Horvath, D. and Lisurek, M. and Rupp, B. and Kuhne, R. and Specker, E. and von Kries, J. and Rognan, D. and Andersson, C. D. and Almqvist, F. and Elofsson, M. and Enqvist, P. A. and Gustavsson, A. L. and Remez, N. and Mestres, J. and Marcou, G. and Varnek, A. and Hibert, M. and Quintana, J. and Frank, R.

Design of a general-purpose European compound screening library for EU-OPENSCREEN

ChemMedChem (2014)

9, 2309-26

10.1002/cmdc.201402126

Horvath, D. and Marcou, G. and Varnek, A.

Do not hesitate to use Tversky-and other hints for successful active analogue searches with feature count descriptors

J Chem Inf Model (2013)

53, 1543-62

10.1021/ci400106g

Horvath, D. and Marcou, G. and Varnek, A.

Monitoring of the Conformational Space of Dipeptides by Generative Topographic Mapping

Mol Inform (2018)

37,

10.1002/minf.201700115

Horvath, D. and Marcou, G. and Varnek, A. and Kayastha, S. and de la Vega de Leon, A. and Bajorath, J.

Prediction of Activity Cliffs Using Condensed Graphs of Reaction Representations, Descriptor Recombination, Support Vector Machine Classification, and Support Vector Regression

J Chem Inf Model (2016)

56, 1631-40

10.1021/acs.jcim.6b00359

Houel, E. and Fleury, M. and Odonne, G. and Nardella, F. and Bourdy, G. and Vonthron-Senecheau, C. and Villa, P. and Obrecht, A. and Eparvier, V. and Deharo, E. and Stien, D.

Antiplasmodial and anti-inflammatory effects of an antimalarial remedy from the Wayana Amerindians, French Guiana: takamalaime (Psidium acutangulum Mart. ex DC., Myrtaceae)

J Ethnopharmacol (2015)

166, 279-85

10.1016/j.jep.2015.03.015

Galy, R. and Bergeret, F. and Keller, D. and Mourey, L. and Prevost, G. and Maveyraud, L.

Crystallization and preliminary crystallographic studies of both components of the staphylococcal LukE-LukD leukotoxin

Acta Crystallogr Sect F Struct Biol Cryst Commun (2012)

68, 663-7

10.1107/S1744309112014662

Galzi, J. L. and Hachet-Haas, M. and Bonnet, D. and Daubeuf, F. and Lecat, S. and Hibert, M. and Haiech, J. and Frossard, N.

Neutralizing endogenous chemokines with small molecules. Principles and potential therapeutic applications

Pharmacol Ther (2010)

126, 39-55

10.1016/j.pharmthera.2009.12.003

Galzi, J. L. and Ilien, B.

[G protein-coupled receptors: allosteric regulators of cell metabolism]

Med Sci (Paris) (2012)

28, 852-7

10.1051/medsci/20122810013

Galzi, J. L. and Ruggiu, F. and Gizzi, P. and Didier, B.

[Quality control of chemical libraries]

Med Sci (Paris) (2015)

31, 660-6

10.1051/medsci/20153106020

Ganesan, S. and Luu, T. T. and Chambers, B. J. and Meinke, S. and Brodin, P. and Vivier, E. and Wetzel, D. M. and Koleske, A. J. and Kadri, N. and Hoglund, P.

The Abl-1 Kinase is Dispensable for NK Cell Inhibitory Signalling and is not Involved in Murine NK Cell Education

Scand J Immunol (2017)

86, 135-142

10.1111/sji.12574

Garcia-Alles, L. F. and Collmann, A. and Versluis, C. and Lindner, B. and Guiard, J. and Maveyraud, L. and Huc, E. and Im, J. S. and Sansano, S. and Brando, T. and Julien, S. and Prandi, J. and Gilleron, M. and Porcelli, S. A. and de la Salle, H. and Heck, A. J. and Mori, L. and Puzo, G. and Mourey, L. and De Libero, G.

Structural reorganization of the antigen-binding groove of human CD1b for presentation of mycobacterial sulfoglycolipids

Proc Natl Acad Sci U S A (2011)

108, 17755-60

10.1073/pnas.1110118108

Garcia-Alles, L. F. and Giacometti, G. and Versluis, C. and Maveyraud, L. and de Paepe, D. and Guiard, J. and Tranier, S. and Gilleron, M. and Prandi, J. and Hanau, D. and Heck, A. J. and Mori, L. and De Libero, G. and Puzo, G. and Mourey, L. and de la Salle, H.

Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes

Proc Natl Acad Sci U S A (2011)

108, 13230-5

10.1073/pnas.1105627108

Garcia-Castillo, M. D. and Tran, T. and Bobard, A. and Renard, H. F. and Rathjen, S. J. and Dransart, E. and Stechmann, B. and Lamaze, C. and Lord, M. and Cintrat, J. C. and Enninga, J. and Tartour, E. and Johannes, L.

Retrograde transport is not required for cytosolic translocation of the B-subunit of Shiga toxin

J Cell Sci (2015)

128, 2373-87

10.1242/jcs.169383

Garcia-Cattaneo, A. and Gobert, F. X. and Muller, M. and Toscano, F. and Flores, M. and Lescure, A. and Del Nery, E. and Benaroch, P.

Cleavage of Toll-like receptor 3 by cathepsins B and H is essential for signaling

Proc Natl Acad Sci U S A (2012)

109, 9053-8

10.1073/pnas.1115091109

Garcia-Perez, J. and Rueda, P. and Alcami, J. and Rognan, D. and Arenzana-Seisdedos, F. and Lagane, B. and Kellenberger, E.

Allosteric model of maraviroc binding to CC chemokine receptor 5 (CCR5)

J Biol Chem (2011)

286, 33409-21

10.1074/jbc.M111.279596

Gaspar, H. A. and Baskin, II and Marcou, G. and Horvath, D. and Varnek, A.

Chemical data visualization and analysis with incremental generative topographic mapping: big data challenge

J Chem Inf Model (2015)

55, 84-94

10.1021/ci500575y

Gaspar, H. A. and Baskin, II and Marcou, G. and Horvath, D. and Varnek, A.

GTM-Based QSAR Models and Their Applicability Domains

Mol Inform (2015)

34, 348-56

10.1002/minf.201400153

Gaspar, H. A. and Baskin, II and Marcou, G. and Horvath, D. and Varnek, A.

Stargate GTM: Bridging Descriptor and Activity Spaces

J Chem Inf Model (2015)

55, 2403-10

10.1021/acs.jcim.5b00398

Gaspar, H. A. and Marcou, G. and Horvath, D. and Arault, A. and Lozano, S. and Vayer, P. and Varnek, A.

Generative topographic mapping-based classification models and their applicability domain: application to the biopharmaceutics Drug Disposition Classification System (BDDCS)

J Chem Inf Model (2013)

53, 3318-25

10.1021/ci400423c

Gasparik, V. and Daubeuf, F. and Hachet-Haas, M. and Rohmer, F. and Gizzi, P. and Haiech, J. and Galzi, J. L. and Hibert, M. and Bonnet, D. and Frossard, N.

Prodrugs of a CXC Chemokine-12 (CXCL12) Neutraligand Prevent Inflammatory Reactions in an Asthma Model in Vivo

ACS Med Chem Lett (2012)

3, 10-4

10.1021/ml200017d

Gautier, B. and Miteva, M. A. and Goncalves, V. and Huguenot, F. and Coric, P. and Bouaziz, S. and Seijo, B. and Gaucher, J. F. and Broutin, I. and Garbay, C. and Lesnard, A. and Rault, S. and Inguimbert, N. and Villoutreix, B. O. and Vidal, M.

Targeting the proangiogenic VEGF-VEGFR protein-protein interface with drug-like compounds by in silico and in vitro screening

Chem Biol (2011)

18, 1631-9

10.1016/j.chembiol.2011.10.016

Gautier, F. M. and Djedaini-Pilard, F. and Grandjean, C.

The iodosulfonamidation of peracetylated glycals revisited: access to 1,2-di-nitrogenated sugars

Carbohydr Res (2011)

346, 577-87

10.1016/j.carres.2011.01.022

Gazanion, E. and Garcia, D. and Silvestre, R. and Gerard, C. and Guichou, J. F. and Labesse, G. and Seveno, M. and Cordeiro-Da-Silva, A. and Ouaissi, A. and Sereno, D. and Vergnes, B.

The Leishmania nicotinamidase is essential for NAD+ production and parasite proliferation

Mol Microbiol (2011)

82, 21-38

10.1111/j.1365-2958.2011.07799.x

Gealageas, R. and Schneider, S. and Humbert, J. P. and Bertin, I. and Schmitt, M. and Laboureyras, E. and Dugave, C. and Mollereau, C. and Simonnet, G. and Bourguignon, J. J. and Simonin, F. and Bihel, F.

Development of sub-nanomolar dipeptidic ligands of neuropeptide FF receptors

Bioorg Med Chem Lett (2012)

22, 7471-4

10.1016/j.bmcl.2012.10.049

Gelin, M. and Delfosse, V. and Allemand, F. and Hoh, F. and Sallaz-Damaz, Y. and Pirocchi, M. and Bourguet, W. and Ferrer, J. L. and Labesse, G. and Guichou, J. F.

Combining 'dry' co-crystallization and in situ diffraction to facilitate ligand screening by X-ray crystallography

Acta Crystallogr D Biol Crystallogr (2015)

71, 1777-87

10.1107/S1399004715010342

Gelin, M. and Poncet-Montange, G. and Assairi, L. and Morellato, L. and Huteau, V. and Dugue, L. and Dussurget, O. and Pochet, S. and Labesse, G.

Screening and in situ synthesis using crystals of a NAD kinase lead to a potent antistaphylococcal compound

Structure (2012)

20, 1107-17

10.1016/j.str.2012.03.024

Geny, C. and Abou Samra, A. and Retailleau, P. and Iorga, B. I. and Nedev, H. and Awang, K. and Roussi, F. and Litaudon, M. and Dumontet, V.

(+)- and (-)-Ecarlottones, Uncommon Chalconoids from Fissistigma latifolium with Pro-Apoptotic Activity

J Nat Prod (2017)

80, 3179-3185

10.1021/acs.jnatprod.7b00494

Geny, C. and Riviere, G. and Bignon, J. and Birlirakis, N. and Guittet, E. and Awang, K. and Litaudon, M. and Roussi, F. and Dumontet, V.

Anacardic Acids from Knema hookeriana as Modulators of Bcl-xL/Bak and Mcl-1/Bid Interactions

J Nat Prod (2016)

79, 838-44

10.1021/acs.jnatprod.5b00915

Gerard, S. and Brechemier, D. and Lefort, A. and Lozano, S. and Abellan Van Kan, G. and Filleron, T. and Mourey, L. and Bernard-Marty, C. and Rouge-Bugat, M. E. and Soler, V. and Vellas, B. and Cesari, M. and Rolland, Y. and Balardy, L.

Body Composition and Anti-Neoplastic Treatment in Adult and Older Subjects - A Systematic Review

J Nutr Health Aging (2016)

20, 878-888

10.1007/s12603-015-0653-2

Gerbier, R. and Alvear-Perez, R. and Margathe, J. F. and Flahault, A. and Couvineau, P. and Gao, J. and De Mota, N. and Dabire, H. and Li, B. and Ceraudo, E. and Hus-Citharel, A. and Esteoulle, L. and Bisoo, C. and Hibert, M. and Berdeaux, A. and Iturrioz, X. and Bonnet, D. and Llorens-Cortes, C.

Development of original metabolically stable apelin-17 analogs with diuretic and cardiovascular effects

FASEB J (2017)

31, 687-700

10.1096/fj.201600784R

Gherbovet, O. and Garcia Alvarez, M. C. and Bignon, J. and Roussi, F.

Original Vinca Derivatives: From P-Glycoprotein Substrates to P-Glycoprotein Inhibitors

J Med Chem (2016)

59, 10774-10780

10.1021/acs.jmedchem.6b00525

Gherbovet, O. and La Spisa, F. and Thoret, S. and Alvarez, M. C. G. and Levaique, H. and Bignon, J. and Roussi, F.

Synthesis and biological evaluation of C-13' substituted 7'-homo-anhydrovinblastine derivatives

Bioorg Med Chem Lett (2015)

25, 1771-1773

10.1016/j.bmcl.2015.02.045

Gherbovet, O. and Sanchez-Murcia, P. A. and Garcia Alvarez, M. C. and Bignon, J. and Thoret, S. and Gago, F. and Roussi, F.

Synthesis and evaluation of hybrid molecules targeting the vinca domain of tubulin

Org Biomol Chem (2015)

13, 3144-54

10.1039/c4ob02114b

Gibert, B. and Hadchity, E. and Czekalla, A. and Aloy, M. T. and Colas, P. and Rodriguez-Lafrasse, C. and Arrigo, A. P. and Diaz-Latoud, C.

Inhibition of heat shock protein 27 (HspB1) tumorigenic functions by peptide aptamers

Oncogene (2011)

30, 3672-81

10.1038/onc.2011.73

Gies, V. and Wagner, A. and Seifert, C. and Guffroy, A. and Fauny, J. D. and Knapp, A. M. and Pasquali, J. L. and Martin, T. and Dumortier, H. and Korganow, A. S. and Soulas-Sprauel, P.

Identification of autoreactive B cells with labeled nucleosomes

Sci Rep (2017)

7, 602

10.1038/s41598-017-00664-0

Gilson, P. and Josa-Prado, F. and Beauvineau, C. and Naud-Martin, D. and Vanwonterghem, L. and Mahuteau-Betzer, F. and Moreno, A. and Falson, P. and Lafanechere, L. and Frachet, V. and Coll, J. L. and Fernando Diaz, J. and Hurbin, A. and Busser, B.

Identification of pyrrolopyrimidine derivative PP-13 as a novel microtubule-destabilizing agent with promising anticancer properties

Sci Rep (2017)

7, 10209

10.1038/s41598-017-09491-9

Gimadiev, T. R. and Madzhidov, T. I. and Nugmanov, R. I. and Baskin, II and Antipin, I. S. and Varnek, A.

Assessment of tautomer distribution using the condensed reaction graph approach

J Comput Aided Mol Des (2018)

32, 401-414

10.1007/s10822-018-0101-6

Giusiano, S. and Cochet, C. and Filhol, O. and Duchemin-Pelletier, E. and Secq, V. and Bonnier, P. and Carcopino, X. and Boubli, L. and Birnbaum, D. and Garcia, S. and Iovanna, J. and Charpin, C.

Protein kinase CK2alpha subunit over-expression correlates with metastatic risk in breast carcinomas: quantitative immunohistochemistry in tissue microarrays

Eur J Cancer (2011)

47, 792-801

10.1016/j.ejca.2010.11.028

Gladyshev, V. N. and Arner, E. S. and Berry, M. J. and Brigelius-Flohe, R. and Bruford, E. A. and Burk, R. F. and Carlson, B. A. and Castellano, S. and Chavatte, L. and Conrad, M. and Copeland, P. R. and Diamond, A. M. and Driscoll, D. M. and Ferreiro, A. and Flohe, L. and Green, F. R. and Guigo, R. and Handy, D. E. and Hatfield, D. L. and Hesketh, J. and Hoffmann, P. R. and Holmgren, A. and Hondal, R. J. and Howard, M. T. and Huang, K. and Kim, H. Y. and Kim, I. Y. and Kohrle, J. and Krol, A. and Kryukov, G. V. and Lee, B. J. and Lee, B. C. and Lei, X. G. and Liu, Q. and Lescure, A. and Lobanov, A. V. and Loscalzo, J. and Maiorino, M. and Mariotti, M. and Sandeep Prabhu, K. and Rayman, M. P. and Rozovsky, S. and Salinas, G. and Schmidt, E. E. and Schomburg, L. and Schweizer, U. and Simonovic, M. and Sunde, R. A. and Tsuji, P. A. and Tweedie, S. and Ursini, F. and Whanger, P. D. and Zhang, Y.

Selenoprotein Gene Nomenclature

J Biol Chem (2016)

291, 24036-24040

10.1074/jbc.M116.756155

Glavatskikh, M. and Madzhidov, T. and Baskin, II and Horvath, D. and Nugmanov, R. and Gimadiev, T. and Marcou, G. and Varnek, A.

Visualization and Analysis of Complex Reaction Data: the Case of Tautomeric Equilibria

Mol Inform (2018)

,

10.1002/minf.201800056

Glavatskikh, M. and Madzhidov, T. and Solov'ev, V. and Marcou, G. and Horvath, D. and Graton, J. and Le Questel, J. Y. and Varnek, A.

Predictive Models for Halogen-bond Basicity of Binding Sites of Polyfunctional Molecules

Mol Inform (2016)

35, 70-80

10.1002/minf.201500116

Glavatskikh, M. and Madzhidov, T. and Solov'ev, V. and Marcou, G. and Horvath, D. and Varnek, A.

Predictive Models for the Free Energy of Hydrogen Bonded Complexes with Single and Cooperative Hydrogen Bonds

Mol Inform (2016)

35, 629-638

10.1002/minf.201600070

Gobeaux, F. and Fay, N. and Tarabout, C. and Meneau, F. and Meriadec, C. and Delvaux, C. and Cintrat, J. C. and Valery, C. and Artzner, F. and Paternostre, M.

Experimental observation of double-walled peptide nanotubes and monodispersity modeling of the number of walls

Langmuir (2013)

29, 2739-45

10.1021/la304862f

Gobeaux, F. and Fay, N. and Tarabout, C. and Meriadec, C. and Meneau, F. and Ligeti, M. and Buisson, D. A. and Cintrat, J. C. and Nguyen, K. M. and Perrin, L. and Valery, C. and Artzner, F. and Paternostre, M.

Structural role of counterions adsorbed on self-assembled peptide nanotubes

J Am Chem Soc (2012)

134, 723-33

10.1021/ja210299g

Gobeaux, F. and Tarabout, C. and Fay, N. and Meriadec, C. and Ligeti, M. and Buisson, D. A. and Cintrat, J. C. and Artzner, F. and Paternostre, M.

Directing peptide crystallization through curvature control of nanotubes

J Pept Sci (2014)

20, 508-16

10.1002/psc.2647

Gomez-Santacana, X. and Dalton, J. A. R. and Rovira, X. and Pin, J. P. and Goudet, C. and Gorostiza, P. and Giraldo, J. and Llebaria, A.

Positional isomers of bispyridine benzene derivatives induce efficacy changes on mGlu5 negative allosteric modulation

Eur J Med Chem (2017)

127, 567-576

10.1016/j.ejmech.2017.01.013

Gomez-Santacana, X. and Pittolo, S. and Rovira, X. and Lopez, M. and Zussy, C. and Dalton, J. A. and Faucherre, A. and Jopling, C. and Pin, J. P. and Ciruela, F. and Goudet, C. and Giraldo, J. and Gorostiza, P. and Llebaria, A.

Illuminating Phenylazopyridines To Photoswitch Metabotropic Glutamate Receptors: From the Flask to the Animals

ACS Cent Sci (2017)

3, 81-91

10.1021/acscentsci.6b00353

Gondoin, A. and Hampe, C. and Eudes, R. and Fayolle, C. and Pierre-Eugene, C. and Miteva, M. and Villoutreix, B. O. and Charnay-Pouget, F. and Aitken, D. J. and Issad, T. and Burnol, A. F.

Identification of insulin-sensitizing molecules acting by disrupting the interaction between the Insulin Receptor and Grb14

Sci Rep (2017)

7, 16901

10.1038/s41598-017-17122-6

Gonzalez-Hilarion, S. and Beghyn, T. and Jia, J. and Debreuck, N. and Berte, G. and Mamchaoui, K. and Mouly, V. and Gruenert, D. C. and Deprez, B. and Lejeune, F.

Rescue of nonsense mutations by amlexanox in human cells

Orphanet J Rare Dis (2012)

7, 58

10.1186/1750-1172-7-58

Gounant, V. and Fleury-Feith, J.

[Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). Experience of Tenon hospital (HU Est parisien, AP-HP Paris). The point of view of the pneumologist, the point of view of the cytologist]

Ann Pathol (2012)

32, S84-8

10.1016/j.annpat.2012.07.029

Gounant, V. and Ninane, V. and Janson, X. and Colombat, M. and Wislez, M. and Grunenwald, D. and Bernaudin, J. F. and Cadranel, J. and Fleury-Feith, J.

Release of metal particles from needles used for transbronchial needle aspiration

Chest (2011)

139, 138-43

10.1378/chest.10-0371

Goy-Thollot, I. and Giger, U. and Boisvineau, C. and Perrin, R. and Guidetti, M. and Chaprier, B. and Barthelemy, A. and Pouzot-Nevoret, C. and Canard, B.

Pre- and Post-Transfusion Alloimmunization in Dogs Characterized by 2 Antiglobulin-Enhanced Cross-match Tests

J Vet Intern Med (2017)

31, 1420-1429

10.1111/jvim.14801

Grandin, C. and Hourani, M. L. and Janin, Y. L. and Dauzonne, D. and Munier-Lehmann, H. and Paturet, A. and Taborik, F. and Vabret, A. and Contamin, H. and Tangy, F. and Vidalain, P. O.

Respiratory syncytial virus infection in macaques is not suppressed by intranasal sprays of pyrimidine biosynthesis inhibitors

Antiviral Res (2016)

125, 58-62

10.1016/j.antiviral.2015.11.006

Grandjean, C. and Latour, J. M. and Cotting, J. and Fazan, M. C. and Leteurtre, S. and Ramelet, A. S.

Measurement of parent satisfaction in the paediatric intensive care unit - Translation, cultural adaptation and psychometric equivalence for the French-speaking version of the EMPATHIC-65 questionnaire

Intensive Crit Care Nurs (2017)

38, 40-45

10.1016/j.iccn.2016.09.001

Grandjean, C. and Wade, T. K. and Ropartz, D. and Ernst, L. and Wade, W. F.

Acid-detoxified Inaba lipopolysaccharide (pmLPS) is a superior cholera conjugate vaccine immunogen than hydrazine-detoxified lipopolysaccharide and induces vibriocidal and protective antibodies

Pathog Dis (2013)

67, 136-58

10.1111/2049-632X.12022

Grandjean, C. L. and Montalvao, F. and Celli, S. and Michonneau, D. and Breart, B. and Garcia, Z. and Perro, M. and Freytag, O. and Gerdes, C. A. and Bousso, P.

Intravital imaging reveals improved Kupffer cell-mediated phagocytosis as a mode of action of glycoengineered anti-CD20 antibodies

Sci Rep (2016)

6, 34382

10.1038/srep34382

Gravis, G. and Boher, J. M. and Fizazi, K. and Joly, F. and Priou, F. and Marino, P. and Latorzeff, I. and Delva, R. and Krakowski, I. and Laguerre, B. and Walz, J. and Rolland, F. and Theodore, C. and Deplanque, G. and Ferrero, J. M. and Pouessel, D. and Mourey, L. and Beuzeboc, P. and Zanetta, S. and Habibian, M. and Berdah, J. F. and Dauba, J. and Baciuchka, M. and Platini, C. and Linassier, C. and Labourey, J. L. and Machiels, J. P. and El Kouri, C. and Ravaud, A. and Suc, E. and Eymard, J. C. and Hasbini, A. and Bousquet, G. and Soulie, M. and Oudard, S.

Prognostic Factors for Survival in Noncastrate Metastatic Prostate Cancer: Validation of the Glass Model and Development of a Novel Simplified Prognostic Model

Eur Urol (2015)

68, 196-204

10.1016/j.eururo.2014.09.022

Gravis, G. and Boher, J. M. and Joly, F. and Soulie, M. and Albiges, L. and Priou, F. and Latorzeff, I. and Delva, R. and Krakowski, I. and Laguerre, B. and Rolland, F. and Theodore, C. and Deplanque, G. and Ferrero, J. M. and Culine, S. and Mourey, L. and Beuzeboc, P. and Habibian, M. and Oudard, S. and Fizazi, K. and Getug

Androgen Deprivation Therapy (ADT) Plus Docetaxel Versus ADT Alone in Metastatic Non castrate Prostate Cancer: Impact of Metastatic Burden and Long-term Survival Analysis of the Randomized Phase 3 GETUG-AFU15 Trial

Eur Urol (2016)

70, 256-62

10.1016/j.eururo.2015.11.005

Gros, C. and Fleury, L. and Nahoum, V. and Faux, C. and Valente, S. and Labella, D. and Cantagrel, F. and Rilova, E. and Bouhlel, M. A. and David-Cordonnier, M. H. and Dufau, I. and Ausseil, F. and Mai, A. and Mourey, L. and Lacroix, L. and Arimondo, P. B.

New insights on the mechanism of quinoline-based DNA Methyltransferase inhibitors

J Biol Chem (2015)

290, 6293-302

10.1074/jbc.M114.594671

Guen, V. J. and Edvardson, S. and Fraenkel, N. D. and Fattal-Valevski, A. and Jalas, C. and Anteby, I. and Shaag, A. and Dor, T. and Gillis, D. and Kerem, E. and Lees, J. A. and Colas, P. and Elpeleg, O.

A homozygous deleterious CDK10 mutation in a patient with agenesis of corpus callosum, retinopathy, and deafness

Am J Med Genet A (2018)

176, 92-98

10.1002/ajmg.a.38506

Guerin, M. and Guillemot, J. and Thouennon, E. and Pierre, A. and El-Yamani, F. Z. and Montero-Hadjadje, M. and Dubessy, C. and Magoul, R. and Lihrmann, I. and Anouar, Y. and Yon, L.

Granins and their derived peptides in normal and tumoral chromaffin tissue: Implications for the diagnosis and prognosis of pheochromocytoma

Regul Pept (2010)

165, 21-9

10.1016/j.regpep.2010.06.003

Gug, F. and Oumata, N. and Tribouillard-Tanvier, D. and Voisset, C. and Desban, N. and Bach, S. and Blondel, M. and Galons, H.

Synthesis of conjugates of 6-aminophenanthridine and guanabenz, two structurally unrelated prion inhibitors, for the determination of their cellular targets by affinity chromatography

Bioconjug Chem (2010)

21, 279-88

10.1021/bc900314n

Guichou, J. F. and Labesse, G.

Fragment and conquer: from structure to complexes to function

Structure (2012)

20, 1617-9

10.1016/j.str.2012.09.008

Guilini, C. and Baehr, C. and Schaeffer, E. and Gizzi, P. and Rufi, F. and Haiech, J. and Weiss, E. and Bonnet, D. and Galzi, J. L.

New fluorescein precursors for live bacteria detection

Anal Chem (2015)

87, 8858-66

10.1021/acs.analchem.5b02100

Guillaud-Bataille, M. and Ragazzon, B. and de Reynies, A. and Chevalier, C. and Francillard, I. and Barreau, O. and Steunou, V. and Guillemot, J. and Tissier, F. and Rizk-Rabin, M. and Rene-Corail, F. and Al Ghuzlan, A. and Assie, G. and Bertagna, X. and Baudin, E. and Le Bouc, Y. and Bertherat, J. and Clauser, E.

IGF2 promotes growth of adrenocortical carcinoma cells, but its overexpression does not modify phenotypic and molecular features of adrenocortical carcinoma

PLoS One (2014)

9, e103744

10.1371/journal.pone.0103744

Guillemet, E. and Tran, S. L. and Cadot, C. and Rognan, D. and Lereclus, D. and Ramarao, N.

Glucose 6P binds and activates HlyIIR to repress Bacillus cereus haemolysin hlyII gene expression

PLoS One (2013)

8, e55085

10.1371/journal.pone.0055085

Guillemot, J. and Guerin, M. and Thouennon, E. and Montero-Hadjadje, M. and Leprince, J. and Lefebvre, H. and Klein, M. and Muresan, M. and Anouar, Y. and Yon, L.

Characterization and plasma measurement of the WE-14 peptide in patients with pheochromocytoma

PLoS One (2014)

9, e88698

10.1371/journal.pone.0088698

Guillemot, J. and Laborie, C. and Dutriez-Casteloot, I. and Maron, M. and Deloof, S. and Lesage, J. and Breton, C. and Vieau, D.

Could maternal perinatal atypical antipsychotic treatments program later metabolic diseases in the offspring?

Eur J Pharmacol (2011)

667, 13-6

10.1016/j.ejphar.2011.05.076

Guillemot, J. and Lukaszewski, M. A. and Montel, V. and Delahaye, F. and Mayeur, S. and Laborie, C. and Dickes-Coopman, A. and Dutriez-Casteloot, I. and Lesage, J. and Breton, C. and Vieau, D.

Influence of prenatal undernutrition on the effects of clozapine and aripiprazole in the adult male rats: relevance to a neurodevelopmental origin of schizophrenia?

Eur J Pharmacol (2011)

667, 402-9

10.1016/j.ejphar.2011.04.011

Guillemot, J. and Thouennon, E. and Guerin, M. and Vallet-Erdtmann, V. and Ravni, A. and Montero-Hadjadje, M. and Lefebvre, H. and Klein, M. and Muresan, M. and Seidah, N. G. and Anouar, Y. and Yon, L.

Differential expression and processing of secretogranin II in relation to the status of pheochromocytoma: implications for the production of the tumoral marker EM66

J Mol Endocrinol (2012)

48, 115-27

10.1530/JME-11-0077

Guillemyn, K. and Starnowska, J. and Lagard, C. and Dyniewicz, J. and Rojewska, E. and Mika, J. and Chung, N. N. and Utard, V. and Kosson, P. and Lipkowski, A. W. and Chevillard, L. and Arranz-Gibert, P. and Teixido, M. and Megarbane, B. and Tourwe, D. and Simonin, F. and Przewlocka, B. and Schiller, P. W. and Ballet, S.

Bifunctional Peptide-Based Opioid Agonist-Nociceptin Antagonist Ligands for Dual Treatment of Acute and Neuropathic Pain

J Med Chem (2016)

59, 3777-92

10.1021/acs.jmedchem.5b01976

Guillen, J. and Lichiere, J. and Rabah, N. and Beitzel, B. F. and Canard, B. and Coutard, B.

Structural and biophysical analysis of sequence insertions in the Venezuelan Equine Encephalitis Virus macro domain

Virus Res (2015)

201, 94-100

10.1016/j.virusres.2015.02.018

Guillet, V. and Galandrin, S. and Maveyraud, L. and Ladeveze, S. and Mariaule, V. and Bon, C. and Eynard, N. and Daffe, M. and Marrakchi, H. and Mourey, L.

Insight into Structure-Function Relationships and Inhibition of the Fatty Acyl-AMP Ligase (FadD32) Orthologs from Mycobacteria

J Biol Chem (2016)

291, 7973-89

10.1074/jbc.M115.712612

Gupta, N. and Noel, R. and Goudet, A. and Hinsinger, K. and Michau, A. and Pons, V. and Abdelkafi, H. and Secher, T. and Shima, A. and Shtanko, O. and Sakurai, Y. and Cojean, S. and Pomel, S. and Lievin-Le Moal, V. and Leignel, V. and Herweg, J. A. and Fischer, A. and Johannes, L. and Harrison, K. and Beard, P. M. and Clayette, P. and Le Grand, R. and Rayner, J. O. and Rudel, T. and Vacus, J. and Loiseau, P. M. and Davey, R. A. and Oswald, E. and Cintrat, J. C. and Barbier, J. and Gillet, D.

Inhibitors of retrograde trafficking active against ricin and Shiga toxins also protect cells from several viruses, Leishmania and Chlamydiales

Chem Biol Interact (2017)

267, 96-103

10.1016/j.cbi.2016.10.005

Gupta, N. and Pons, V. and Noel, R. and Buisson, D. A. and Michau, A. and Johannes, L. and Gillet, D. and Barbier, J. and Cintrat, J. C.

(S)-N-Methyldihydroquinazolinones are the Active Enantiomers of Retro-2 Derived Compounds against Toxins

ACS Med Chem Lett (2014)

5, 94-7

10.1021/ml400457j

Gutierrez, T. J. and Herniou-Julien, C. and Alvarez, K. and Alvarez, V. A.

Structural properties and in vitro digestibility of edible and pH-sensitive films made from guinea arrowroot starch and wastes from wine manufacture

Carbohydr Polym (2018)

184, 135-143

10.1016/j.carbpol.2017.12.039

Guyant, P. and Corbel, V. and Guerin, P. J. and Lautissier, A. and Nosten, F. and Boyer, S. and Coosemans, M. and Dondorp, A. M. and Sinou, V. and Yeung, S. and White, N.

Past and new challenges for malaria control and elimination: the role of operational research for innovation in designing interventions

Malar J (2015)

14, 279

10.1186/s12936-015-0802-4

Guyon, F. and Martz, F. and Vavrusa, M. and Becot, J. and Rey, J. and Tuffery, P.

BCSearch: fast structural fragment mining over large collections of protein structures

Nucleic Acids Res (2015)

43, W378-82

10.1093/nar/gkv492

Guyon, F. and Tuffery, P.

Fast protein fragment similarity scoring using a Binet-Cauchy kernel

Bioinformatics (2014)

30, 784-91

10.1093/bioinformatics/btt618

Ha, V. T. and Kien, V. T. and Binh le, H. and Tien, V. D. and My, N. T. and Nam, N. H. and Baltas, M. and Hahn, H. and Han, B. W. and Thao do, T. and Vu, T. K.

Design, synthesis and biological evaluation of novel hydroxamic acids bearing artemisinin skeleton

Bioorg Chem (2016)

66, 63-71

10.1016/j.bioorg.2016.03.008

Haiech, J. and Gendrault, Y. and Kilhoffer, M. C. and Ranjeva, R. and Madec, M. and Lallement, C.

A general framework improving teaching ligand binding to a macromolecule

Biochim Biophys Acta (2014)

1843, 2348-55

10.1016/j.bbamcr.2014.03.013

Hamdi, A. and Colas, P.

Yeast two-hybrid methods and their applications in drug discovery

Trends Pharmacol Sci (2012)

33, 109-18

10.1016/j.tips.2011.10.008

Hamdi, A. and Lesnard, A. and Suzanne, P. and Robert, T. and Miteva, M. A. and Pellerano, M. and Didier, B. and Ficko-Blean, E. and Lobstein, A. and Hibert, M. and Rault, S. and Morris, M. C. and Colas, P.

Tampering with cell division by using small-molecule inhibitors of CDK-CKS protein interactions

Chembiochem (2015)

16, 432-9

10.1002/cbic.201402579

Hammam, K. and Saez-Ayala, M. and Rebuffet, E. and Gros, L. and Lopez, S. and Hajem, B. and Humbert, M. and Baudelet, E. and Audebert, S. and Betzi, S. and Lugari, A. and Combes, S. and Letard, S. and Casteran, N. and Mansfield, C. and Moussy, A. and De Sepulveda, P. and Morelli, X. and Dubreuil, P.

Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology

Nat Commun (2017)

8, 1420

10.1038/s41467-017-01582-5

Hammoud, H. and Elhabazi, K. and Quillet, R. and Bertin, I. and Utard, V. and Laboureyras, E. and Bourguignon, J. J. and Bihel, F. and Simonnet, G. and Simonin, F. and Schmitt, M.

Aminoguanidine Hydrazone Derivatives as Nonpeptide NPFF1 Receptor Antagonists Reverse Opioid Induced Hyperalgesia

ACS Chem Neurosci (2018)

,

10.1021/acschemneuro.8b00099

Hamon, V. and Bourgeas, R. and Ducrot, P. and Theret, I. and Xuereb, L. and Basse, M. J. and Brunel, J. M. and Combes, S. and Morelli, X. and Roche, P.

2P2I HUNTER: a tool for filtering orthosteric protein-protein interaction modulators via a dedicated support vector machine

J R Soc Interface (2014)

11, 20130860

10.1098/rsif.2013.0860

Hannauer, M. and Schafer, M. and Hoegy, F. and Gizzi, P. and Wehrung, P. and Mislin, G. L. and Budzikiewicz, H. and Schalk, I. J.

Biosynthesis of the pyoverdine siderophore of Pseudomonas aeruginosa involves precursors with a myristic or a myristoleic acid chain

FEBS Lett (2012)

586, 96-101

10.1016/j.febslet.2011.12.004

Harigua-Souiai, E. and Abdelkrim, Y. Z. and Bassoumi-Jamoussi, I. and Zakraoui, O. and Bouvier, G. and Essafi-Benkhadir, K. and Banroques, J. and Desdouits, N. and Munier-Lehmann, H. and Barhoumi, M. and Tanner, N. K. and Nilges, M. and Blondel, A. and Guizani, I.

Identification of novel leishmanicidal molecules by virtual and biochemical screenings targeting Leishmania eukaryotic translation initiation factor 4A

PLoS Negl Trop Dis (2018)

12, e0006160

10.1371/journal.pntd.0006160

Harrison, K. and Haga, I. R. and Pechenick Jowers, T. and Jasim, S. and Cintrat, J. C. and Gillet, D. and Schmitt-John, T. and Digard, P. and Beard, P. M.

Vaccinia virus uses retromer-independent cellular retrograde transport pathways to facilitate the wrapping of intracellular mature virions during viral morphogenesis

J Virol (2016)

,

10.1128/JVI.01464-16

Houel, E. and Nardella, F. and Jullian, V. and Valentin, A. and Vonthron-Senecheau, C. and Villa, P. and Obrecht, A. and Kaiser, M. and Bourreau, E. and Odonne, G. and Fleury, M. and Bourdy, G. and Eparvier, V. and Deharo, E. and Stien, D.

Wayanin and guaijaverin, two active metabolites found in a Psidium acutangulum Mart. ex DC (syn. P. persoonii McVaugh) (Myrtaceae) antimalarial decoction from the Wayana Amerindians

J Ethnopharmacol (2016)

187, 241-8

10.1016/j.jep.2016.04.053

Hounsou, C. and Baehr, C. and Gasparik, V. and Alili, D. and Belhocine, A. and Rodriguez, T. and Dupuis, E. and Roux, T. and Mann, A. and Heissler, D. and Pin, J. P. and Durroux, T. and Bonnet, D. and Hibert, M.

From the Promiscuous Asenapine to Potent Fluorescent Ligands Acting at a Series of Aminergic G-Protein-Coupled Receptors

J Med Chem (2018)

61, 174-188

10.1021/acs.jmedchem.7b01220

Hounsou, C. and Margathe, J. F. and Oueslati, N. and Belhocine, A. and Dupuis, E. and Thomas, C. and Mann, A. and Ilien, B. and Rognan, D. and Trinquet, E. and Hibert, M. and Pin, J. P. and Bonnet, D. and Durroux, T.

Time-resolved FRET binding assay to investigate hetero-oligomer binding properties: proof of concept with dopamine D1/D3 heterodimer

ACS Chem Biol (2015)

10, 466-74

10.1021/cb5007568

Hountondji, C. and Bulygin, K. and Crechet, J. B. and Woisard, A. and Tuffery, P. and Nakayama, J. and Frolova, L. and Nierhaus, K. H. and Karpova, G. and Baouz, S.

The CCA-end of P-tRNA Contacts Both the Human RPL36AL and the A-site Bound Translation Termination Factor eRF1 at the Peptidyl Transferase Center of the Human 80S Ribosome

Open Biochem J (2014)

8, 52-67

10.2174/1874091X01408010052

Hountondji, C. and Bulygin, K. and Woisard, A. and Tuffery, P. and Crechet, J. B. and Pech, M. and Nierhaus, K. H. and Karpova, G. and Baouz, S.

Lys53 of ribosomal protein L36AL and the CCA end of a tRNA at the P/E hybrid site are in close proximity on the human ribosome

Chembiochem (2012)

13, 1791-7

10.1002/cbic.201200208

Houze, S. and Hoang, N. T. and Lozach, O. and Le Bras, J. and Meijer, L. and Galons, H. and Demange, L.

Several human cyclin-dependent kinase inhibitors, structurally related to roscovitine, are new anti-malarial agents

Molecules (2014)

19, 15237-57

10.3390/molecules190915237

Hu, F. and Shi, X. and Li, B. and Huang, X. and Morelli, X. and Shi, N.

Structural basis for the interaction between the Golgi reassembly-stacking protein GRASP65 and the Golgi matrix protein GM130

J Biol Chem (2015)

290, 26373-82

10.1074/jbc.M115.657940

Huang, S. and Cao, J. and Jiang, M. and Labesse, G. and Liu, J. and Pin, J. P. and Rondard, P.

Interdomain movements in metabotropic glutamate receptor activation

Proc Natl Acad Sci U S A (2011)

108, 15480-5

10.1073/pnas.1107775108

Huillard, E. and Ziercher, L. and Blond, O. and Wong, M. and Deloulme, J. C. and Souchelnytskyi, S. and Baudier, J. and Cochet, C. and Buchou, T.

Disruption of CK2beta in embryonic neural stem cells compromises proliferation and oligodendrogenesis in the mouse telencephalon

Mol Cell Biol (2010)

30, 2737-49

10.1128/MCB.01566-09

Huynh, T. H. and Erichsen, M. N. and Tora, A. S. and Goudet, C. and Sagot, E. and Assaf, Z. and Thomsen, C. and Brodbeck, R. and Stensbol, T. B. and Bjorn-Yoshimoto, W. E. and Nielsen, B. and Pin, J. P. and Gefflaut, T. and Bunch, L.

New 4-Functionalized Glutamate Analogues Are Selective Agonists at Metabotropic Glutamate Receptor Subtype 2 or Selective Agonists at Metabotropic Glutamate Receptor Group III

J Med Chem (2016)

59, 914-24

10.1021/acs.jmedchem.5b01333

Iacopetta, D. and Rosano, C. and Puoci, F. and Parisi, O. I. and Saturnino, C. and Caruso, A. and Longo, P. and Ceramella, J. and Malzert-Freon, A. and Dallemagne, P. and Rault, S. and Sinicropi, M. S.

Multifaceted properties of 1,4-dimethylcarbazoles: Focus on trimethoxybenzamide and trimethoxyphenylurea derivatives as novel human topoisomerase II inhibitors

Eur J Pharm Sci (2017)

96, 263-272

10.1016/j.ejps.2016.09.039

Igonet, S. and Raingeval, C. and Cecon, E. and Pucic-Bakovic, M. and Lauc, G. and Cala, O. and Baranowski, M. and Perez, J. and Jockers, R. and Krimm, I. and Jawhari, A.

Enabling STD-NMR fragment screening using stabilized native GPCR: A case study of adenosine receptor

Sci Rep (2018)

8, 8142

10.1038/s41598-018-26113-0

Isambert, N. and Sanchez Duque Mdel, M. and Plaquevent, J. C. and Genisson, Y. and Rodriguez, J. and Constantieux, T.

Multicomponent reactions and ionic liquids: a perfect synergy for eco-compatible heterocyclic synthesis

Chem Soc Rev (2011)

40, 1347-57

10.1039/c0cs00013b

Isberg, V. and de Graaf, C. and Bortolato, A. and Cherezov, V. and Katritch, V. and Marshall, F. H. and Mordalski, S. and Pin, J. P. and Stevens, R. C. and Vriend, G. and Gloriam, D. E.

Generic GPCR residue numbers - aligning topology maps while minding the gaps

Trends Pharmacol Sci (2015)

36, 22-31

10.1016/j.tips.2014.11.001

Isvoran, A. and Louet, M. and Vladoiu, D. L. and Craciun, D. and Loriot, M. A. and Villoutreix, B. O. and Miteva, M. A.

Pharmacogenomics of the cytochrome P450 2C family: impacts of amino acid variations on drug metabolism

Drug Discov Today (2017)

22, 366-376

10.1016/j.drudis.2016.09.015

Le Cigne, A. and Menil-Philippot, V. and Fleury, F. and Takahashi, M. and Thiriet, C.

Transient expression of RAD51 in the late G2-phase is required for cell cycle progression in synchronous Physarum cells

Genes Cells (2014)

19, 755-65

10.1111/gtc.12174

Le Floch, C. and Le Gall, E. and Leonel, E. and Martens, T. and Cresteil, T.

Synthesis and cytotoxic evaluation of novel paraconic acid analogs

Bioorg Med Chem Lett (2011)

21, 7054-8

10.1016/j.bmcl.2011.09.092

Le Floch, C. and Le Gall, E. and Sengmany, S. and Renevret, P. and Leonel, E. and Martens, T. and Cresteil, T.

Synthesis of 2,3-di- and 2,2,3-trisubstituted-3-methoxycarbonyl-gamma-butyrolactones as potent antitumor agents

Eur J Med Chem (2015)

89, 654-70

10.1016/j.ejmech.2014.10.074

le Maire, A. and Gelin, M. and Pochet, S. and Hoh, F. and Pirocchi, M. and Guichou, J. F. and Ferrer, J. L. and Labesse, G.

In-plate protein crystallization, in situ ligand soaking and X-ray diffraction

Acta Crystallogr D Biol Crystallogr (2011)

67, 747-55

10.1107/S0907444911023249

Le, N. H. and Molle, V. and Eynard, N. and Miras, M. and Stella, A. and Bardou, F. and Galandrin, S. and Guillet, V. and Andre-Leroux, G. and Bellinzoni, M. and Alzari, P. and Mourey, L. and Burlet-Schiltz, O. and Daffe, M. and Marrakchi, H.

Ser/Thr Phosphorylation Regulates the Fatty Acyl-AMP Ligase Activity of FadD32, an Essential Enzyme in Mycolic Acid Biosynthesis

J Biol Chem (2016)

291, 22793-22805

10.1074/jbc.M116.748053

Lecat, S. and Belemnaba, L. and Galzi, J. L. and Bucher, B.

Neuropeptide Y receptor mediates activation of ERK1/2 via transactivation of the IGF receptor

Cell Signal (2015)

27, 1297-304

10.1016/j.cellsig.2015.03.016

Lecat, S. and Matthes, H. W. and Pepperkok, R. and Simpson, J. C. and Galzi, J. L.

A Fluorescent Live Imaging Screening Assay Based on Translocation Criteria Identifies Novel Cytoplasmic Proteins Implicated in G Protein-coupled Receptor Signaling Pathways

Mol Cell Proteomics (2015)

14, 1385-99

10.1074/mcp.M114.046698

Lecat, S. and Ouedraogo, M. and Cherrier, T. and Noulet, F. and Ronde, P. and Glasser, N. and Galzi, J. L. and Mely, Y. and Takeda, K. and Bucher, B.

Contribution of a tyrosine-based motif to cellular trafficking of wild-type and truncated NPY Y(1) receptors

Cell Signal (2011)

23, 228-38

10.1016/j.cellsig.2010.09.007

Lecat-Guillet, N. and Monnier, C. and Rovira, X. and Kniazeff, J. and Lamarque, L. and Zwier, J. M. and Trinquet, E. and Pin, J. P. and Rondard, P.

FRET-Based Sensors Unravel Activation and Allosteric Modulation of the GABAB Receptor

Cell Chem Biol (2017)

24, 360-370

10.1016/j.chembiol.2017.02.011

Lecoeur, H. and Borgne-Sanchez, A. and Chaloin, O. and El-Khoury, R. and Brabant, M. and Langonne, A. and Porceddu, M. and Briere, J. J. and Buron, N. and Rebouillat, D. and Pechoux, C. and Deniaud, A. and Brenner, C. and Briand, J. P. and Muller, S. and Rustin, P. and Jacotot, E.

HIV-1 Tat protein directly induces mitochondrial membrane permeabilization and inactivates cytochrome c oxidase

Cell Death Dis (2012)

3, e282

10.1038/cddis.2012.21

Lecointre, C. and Desrues, L. and Joubert, J. E. and Perzo, N. and Guichet, P. O. and Le Joncour, V. and Brule, C. and Chabbert, M. and Leduc, R. and Prezeau, L. and Laquerriere, A. and Proust, F. and Gandolfo, P. and Morin, F. and Castel, H.

Signaling switch of the urotensin II vasosactive peptide GPCR: prototypic chemotaxic mechanism in glioma

Oncogene (2015)

34, 5080-94

10.1038/onc.2014.433

Lecointre, C. and Simon, V. and Kerneur, C. and Allemand, F. and Fournet, A. and Montarras, I. and Pons, J. L. and Gelin, M. and Brignatz, C. and Urbach, S. and Labesse, G. and Roche, S.

Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation

Structure (2018)

26, 545-554 e4

10.1016/j.str.2018.01.017

Lecoutey, C. and Hedou, D. and Freret, T. and Giannoni, P. and Gaven, F. and Since, M. and Bouet, V. and Ballandonne, C. and Corvaisier, S. and Malzert Freon, A. and Mignani, S. and Cresteil, T. and Boulouard, M. and Claeysen, S. and Rochais, C. and Dallemagne, P.

Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment

Proc Natl Acad Sci U S A (2014)

111, E3825-30

10.1073/pnas.1410315111

Iturrioz, X. and Alvear-Perez, R. and De Mota, N. and Franchet, C. and Guillier, F. and Leroux, V. and Dabire, H. and Le Jouan, M. and Chabane, H. and Gerbier, R. and Bonnet, D. and Berdeaux, A. and Maigret, B. and Galzi, J. L. and Hibert, M. and Llorens-Cortes, C.

Identification and pharmacological properties of E339-3D6, the first nonpeptidic apelin receptor agonist

FASEB J (2010)

24, 1506-17

10.1096/fj.09-140715

Ivashkin, P. and Lemonnier, G. and Tora, A. S. and Pin, J. P. and Goudet, C. and Jubault, P. and Pannecoucke, X.

Synthesis and studies on the mGluR agonist activity of FAP4 stereoisomers

Bioorg Med Chem Lett (2015)

25, 2523-6

10.1016/j.bmcl.2015.04.043

Jacomin, A. C. and Fauvarque, M. O. and Taillebourg, E.

A functional endosomal pathway is necessary for lysosome biogenesis in Drosophila

BMC Cell Biol (2016)

17, 36

10.1186/s12860-016-0115-7

Jacquemin, B. and Lepeule, J. and Boudier, A. and Arnould, C. and Benmerad, M. and Chappaz, C. and Ferran, J. and Kauffmann, F. and Morelli, X. and Pin, I. and Pison, C. and Rios, I. and Temam, S. and Kunzli, N. and Slama, R. and Siroux, V.

Impact of geocoding methods on associations between long-term exposure to urban air pollution and lung function

Environ Health Perspect (2013)

121, 1054-60

10.1289/ehp.1206016

Jacques, S. A. and Leriche, G. and Mosser, M. and Nothisen, M. and Muller, C. D. and Remy, J. S. and Wagner, A.

From solution to in-cell study of the chemical reactivity of acid sensitive functional groups: a rational approach towards improved cleavable linkers for biospecific endosomal release

Org Biomol Chem (2016)

14, 4794-803

10.1039/c6ob00846a

Jagot-Lacoussiere, L. and Faye, A. and Bruzzoni-Giovanelli, H. and Villoutreix, B. O. and Rain, J. C. and Poyet, J. L.

DNA damage-induced nuclear translocation of Apaf-1 is mediated by nucleoporin Nup107

Cell Cycle (2015)

14, 1242-51

10.1080/15384101.2015.1014148

Jagot-Lacoussiere, L. and Kotula, E. and Villoutreix, B. O. and Bruzzoni-Giovanelli, H. and Poyet, J. L.

A Cell-Penetrating Peptide Targeting AAC-11 Specifically Induces Cancer Cells Death

Cancer Res (2016)

76, 5479-90

10.1158/0008-5472.CAN-16-0302

Jang, J. and Stella, A. and Boudou, F. and Levillain, F. and Darthuy, E. and Vaubourgeix, J. and Wang, C. and Bardou, F. and Puzo, G. and Gilleron, M. and Burlet-Schiltz, O. and Monsarrat, B. and Brodin, P. and Gicquel, B. and Neyrolles, O.

Functional characterization of the Mycobacterium tuberculosis serine/threonine kinase PknJ

Microbiology (2010)

156, 1619-31

10.1099/mic.0.038133-0

Jarrahpour, A. and Ebrahimi, E. and Sinou, V. and Latour, C. and Brunel, J. M.

Diastereoselective synthesis of potent antimalarial cis-beta-lactam agents through a [2 + 2] cycloaddition of chiral imines with a chiral ketene

Eur J Med Chem (2014)

87, 364-71

10.1016/j.ejmech.2014.09.077

Jaunet-Lahary, T. and Goupille, A. and Jacquemin, D. and Fleury, F. and Graton, J. and Laurent, A. D.

A Joint Theoretical and Experimental Study of the Behavior of the DIDS Inhibitor and its Derivatives

Chemphyschem (2016)

17, 2434-45

10.1002/cphc.201600107

Jaunet-Lahary, T. and Vercauteren, D. P. and Fleury, F. and Laurent, A. D.

Computational simulations determining disulfonic stilbene derivative bioavailability within human serum albumin

Phys Chem Chem Phys (2018)

20, 18020-18030

10.1039/c8cp00704g

Jean, D. and Thomas, E. and Manie, E. and Renier, A. and de Reynies, A. and Lecomte, C. and Andujar, P. and Fleury-Feith, J. and Galateau-Salle, F. and Giovannini, M. and Zucman-Rossi, J. and Stern, M. H. and Jaurand, M. C.

Syntenic relationships between genomic profiles of fiber-induced murine and human malignant mesothelioma

Am J Pathol (2011)

178, 881-94

10.1016/j.ajpath.2010.10.039

Jlalia, I. and Beauvineau, C. and Beauviere, S. and Onen, E. and Aufort, M. and Beauvineau, A. and Khaba, E. and Herscovici, J. and Meganem, F. and Girard, C.

Automated synthesis of a 96 product-sized library of triazole derivatives using a solid phase supported copper catalyst

Molecules (2010)

15, 3087-120

10.3390/molecules15053087

Jolly, C. and Rousseau, K. and Prezeau, L. and Vol, C. and Tomkiewicz, J. and Dufour, S. and Pasqualini, C.

Functional Characterisation of Eel Dopamine D2 Receptors and Involvement in the Direct Inhibition of Pituitary Gonadotrophins

J Neuroendocrinol (2016)

28,

10.1111/jne.12411

Jourdan, J. P. and Since, M. and El Kihel, L. and Lecoutey, C. and Corvaisier, S. and Legay, R. and Sopkova-de Oliveira Santos, J. and Cresteil, T. and Malzert-Freon, A. and Rochais, C. and Dallemagne, P.

Novel benzylidenephenylpyrrolizinones with pleiotropic activities potentially useful in Alzheimer's disease treatment

Eur J Med Chem (2016)

114, 365-79

10.1016/j.ejmech.2016.03.023

Jourdan, J. P. and Since, M. and El Kihel, L. and Lecoutey, C. and Corvaisier, S. and Legay, R. and Sopkova-de Oliveira Santos, J. and Cresteil, T. and Malzert-Freon, A. and Rochais, C. and Dallemagne, P.

Benzylphenylpyrrolizinones with Anti-amyloid and Radical Scavenging Effects, Potentially Useful in Alzheimer's Disease Treatment

ChemMedChem (2017)

12, 913-916

10.1002/cmdc.201700102

Julien, S. and Tondl, P. and Durand, F. and Dagkessamanskaia, A. and van Tilbeurgh, H. and Francois, J. M. and Mourey, L. and Zerbib, D. and Martin-Yken, H. and Maveyraud, L.

Crystallographic studies of the structured core domain of Knr4 from Saccharomyces cerevisiae

Acta Crystallogr F Struct Biol Commun (2015)

71, 1120-4

10.1107/S2053230X15012522

Kadri, L. and Ferru-Clement, R. and Bacle, A. and Payet, L. A. and Cantereau, A. and Helye, R. and Becq, F. and Jayle, C. and Vandebrouck, C. and Ferreira, T.

Modulation of cellular membrane properties as a potential therapeutic strategy to counter lipointoxication in obstructive pulmonary diseases

Biochim Biophys Acta (2018)

1864, 3069-3084

10.1016/j.bbadis.2018.06.021

Kalhor-Monfared, S. and Beauvineau, C. and Scherman, D. and Girard, C.

Synthesis and cytotoxicity evaluation of aryl triazolic derivatives and their hydroxymethine homologues against B16 melanoma cell line

Eur J Med Chem (2016)

122, 436-441

10.1016/j.ejmech.2016.06.057

Karaki, S. and Becamel, C. and Murat, S. and Mannoury la Cour, C. and Millan, M. J. and Prezeau, L. and Bockaert, J. and Marin, P. and Vandermoere, F.

Quantitative phosphoproteomics unravels biased phosphorylation of serotonin 2A receptor at Ser280 by hallucinogenic versus nonhallucinogenic agonists

Mol Cell Proteomics (2014)

13, 1273-85

10.1074/mcp.M113.036558

Karila, D. and Freret, T. and Bouet, V. and Boulouard, M. and Dallemagne, P. and Rochais, C.

Therapeutic Potential of 5-HT6 Receptor Agonists

J Med Chem (2015)

58, 7901-12

10.1021/acs.jmedchem.5b00179

Karpenko, I. A. and Collot, M. and Richert, L. and Valencia, C. and Villa, P. and Mely, Y. and Hibert, M. and Bonnet, D. and Klymchenko, A. S.

Fluorogenic squaraine dimers with polarity-sensitive folding as bright far-red probes for background-free bioimaging

J Am Chem Soc (2015)

137, 405-12

10.1021/ja5111267

Karpenko, I. A. and Klymchenko, A. S. and Gioria, S. and Kreder, R. and Shulov, I. and Villa, P. and Mely, Y. and Hibert, M. and Bonnet, D.

Squaraine as a bright, stable and environment-sensitive far-red label for receptor-specific cellular imaging

Chem Commun (Camb) (2015)

51, 2960-3

10.1039/c4cc09113b

Karpenko, I. A. and Kreder, R. and Valencia, C. and Villa, P. and Mendre, C. and Mouillac, B. and Mely, Y. and Hibert, M. and Bonnet, D. and Klymchenko, A. S.

Red fluorescent turn-on ligands for imaging and quantifying G protein-coupled receptors in living cells

Chembiochem (2014)

15, 359-63

10.1002/cbic.201300738

Karpenko, I. A. and Margathe, J. F. and Rodriguez, T. and Pflimlin, E. and Dupuis, E. and Hibert, M. and Durroux, T. and Bonnet, D.

Selective nonpeptidic fluorescent ligands for oxytocin receptor: design, synthesis, and application to time-resolved FRET binding assay

J Med Chem (2015)

58, 2547-52

10.1021/jm501395b

Karrout, Y. and Dubuquoy, L. and Piveteau, C. and Siepmann, F. and Moussa, E. and Wils, D. and Beghyn, T. and Neut, C. and Flament, M. P. and Guerin-Deremaux, L. and Dubreuil, L. and Deprez, B. and Desreumaux, P. and Siepmann, J.

In vivo efficacy of microbiota-sensitive coatings for colon targeting: a promising tool for IBD therapy

J Control Release (2015)

197, 121-30

10.1016/j.jconrel.2014.11.006

Kayastha, S. and Horvath, D. and Gilberg, E. and Gutschow, M. and Bajorath, J. and Varnek, A.

Privileged Structural Motif Detection and Analysis Using Generative Topographic Maps

J Chem Inf Model (2017)

57, 1218-1232

10.1021/acs.jcim.7b00128

Kayastha, S. and Kunimoto, R. and Horvath, D. and Varnek, A. and Bajorath, J.

From bird's eye views to molecular communities: two-layered visualization of structure-activity relationships in large compound data sets

J Comput Aided Mol Des (2017)

31, 961-977

10.1007/s10822-017-0070-1

Khater, S. and Canault, B. and Azzimani, T. and Bonnet, P. and West, C.

Thermodynamic enantioseparation behavior of phenylthiohydantoin-amino acid derivatives in supercritical fluid chromatography on polysaccharide chiral stationary phases

J Sep Sci (2018)

41, 1450-1459

10.1002/jssc.201701196

Khatib, A. M. and Lahlil, R. and Scamuffa, N. and Akimenko, M. A. and Ernest, S. and Lomri, A. and Lalou, C. and Seidah, N. G. and Villoutreix, B. O. and Calvo, F. and Siegfried, G.

Zebrafish ProVEGF-C expression, proteolytic processing and inhibitory effect of unprocessed ProVEGF-C during fin regeneration

PLoS One (2010)

5, e11438

10.1371/journal.pone.0011438

Khelifi, I. and Naret, T. and Renko, D. and Hamze, A. and Bernadat, G. and Bignon, J. and Lenoir, C. and Dubois, J. and Brion, J. D. and Provot, O. and Alami, M.

Design, synthesis and anticancer properties of IsoCombretaQuinolines as potent tubulin assembly inhibitors

Eur J Med Chem (2017)

127, 1025-1034

10.1016/j.ejmech.2016.11.012

Khiar, S. and Lucas-Hourani, M. and Nisole, S. and Smith, N. and Helynck, O. and Bourgine, M. and Ruffie, C. and Herbeuval, J. P. and Munier-Lehmann, H. and Tangy, F. and Vidalain, P. O.

Identification of a small molecule that primes the type I interferon response to cytosolic DNA

Sci Rep (2017)

7, 2561

10.1038/s41598-017-02776-z

Kim, J. and Brown, C. M. and Kim, M. K. and Burrows, E. H. and Bach, S. and Lun, D. S. and Falkowski, P. G.

Effect of cell cycle arrest on intermediate metabolism in the marine diatom Phaeodactylum tricornutum

Proc Natl Acad Sci U S A (2017)

114, E8007-E8016

10.1073/pnas.1711642114

Kireeva, N. and Baskin, II and Gaspar, H. A. and Horvath, D. and Marcou, G. and Varnek, A.

Generative Topographic Mapping (GTM): Universal Tool for Data Visualization, Structure-Activity Modeling and Dataset Comparison

Mol Inform (2012)

31, 301-12

10.1002/minf.201100163

Klein, O. and Morel, O. and Perdriolle-Galet, E. and Miton, A. and Bach-Segura, P. and Hascoet, J. M. and Marchal, J. C. and Bouaziz, H. and Kahn, J. P.

[In utero surgery of myelomeningocele in France]

Neurochirurgie (2015)

61, 356-7

10.1016/j.neuchi.2015.06.001

Klimenko, K. and Lyakhov, S. and Shibinskaya, M. and Karpenko, A. and Marcou, G. and Horvath, D. and Zenkova, M. and Goncharova, E. and Amirkhanov, R. and Krysko, A. and Andronati, S. and Levandovskiy, I. and Polishchuk, P. and Kuz'min, V. and Varnek, A.

Virtual screening, synthesis and biological evaluation of DNA intercalating antiviral agents

Bioorg Med Chem Lett (2017)

27, 3915-3919

10.1016/j.bmcl.2017.06.035

Klimenko, K. and Marcou, G. and Horvath, D. and Varnek, A.

Chemical Space Mapping and Structure-Activity Analysis of the ChEMBL Antiviral Compound Set

J Chem Inf Model (2016)

56, 1438-54

10.1021/acs.jcim.6b00192

Kolodych, S. and Michel, C. and Delacroix, S. and Koniev, O. and Ehkirch, A. and Eberova, J. and Cianferani, S. and Renoux, B. and Krezel, W. and Poinot, P. and Muller, C. D. and Papot, S. and Wagner, A.

Development and evaluation of beta-galactosidase-sensitive antibody-drug conjugates

Eur J Med Chem (2017)

142, 376-382

10.1016/j.ejmech.2017.08.008

Kondratovich, E. and Baskin, II and Varnek, A.

Transductive Support Vector Machines: Promising Approach to Model Small and Unbalanced Datasets

Mol Inform (2013)

32, 261-6

10.1002/minf.201200135

Koseki, Y. and Kanetaka, H. and Tsunosaki, J. and Munier-Lehmann, H. and Aoki, S.

Tetrahydro-2-furanyl-2,4(1H,3H)-pyrimidinedione derivatives as novel antibacterial compounds against Mycobacterium

Int J Mycobacteriol (2017)

6, 61-69

10.4103/2212-5531.201893

Kramar, A. and Negrier, S. and Sylvester, R. and Joniau, S. and Mulders, P. and Powles, T. and Bex, A. and Bonnetain, F. and Bossi, A. and Bracarda, S. and Bukowski, R. and Catto, J. and Choueiri, T. K. and Crabb, S. and Eisen, T. and El Demery, M. and Fitzpatrick, J. and Flamand, V. and Goebell, P. J. and Gravis, G. and Houede, N. and Jacqmin, D. and Kaplan, R. and Malavaud, B. and Massard, C. and Melichar, B. and Mourey, L. and Nathan, P. and Pasquier, D. and Porta, C. and Pouessel, D. and Quinn, D. and Ravaud, A. and Rolland, F. and Schmidinger, M. and Tombal, B. and Tosi, D. and Vauleon, E. and Volpe, A. and Wolter, P. and Escudier, B. and Filleron, T. and group, Datecan Renal Cancer

Guidelines for the definition of time-to-event end points in renal cell cancer clinical trials: results of the DATECAN projectdagger

Ann Oncol (2015)

26, 2392-8

10.1093/annonc/mdv380

Krimm, I.

[Fragment-based screening: a promising avenue for drug design]

Med Sci (Paris) (2015)

31, 197-202

10.1051/medsci/20153102017

Krimm, I.

Identifying Protein Allosteric Transitions for Drug Discovery with 1D NMR

ChemMedChem (2017)

12, 901-904

10.1002/cmdc.201700064

Krimm, I. and Lancelin, J. M. and Praly, J. P.

Binding evaluation of fragment-based scaffolds for probing allosteric enzymes

J Med Chem (2012)

55, 1287-95

10.1021/jm201439b

Kuenemann, M. A. and Bourbon, L. M. and Labbe, C. M. and Villoutreix, B. O. and Sperandio, O.

Which three-dimensional characteristics make efficient inhibitors of protein-protein interactions?

J Chem Inf Model (2014)

54, 3067-79

10.1021/ci500487q

Kuenemann, M. A. and Labbe, C. M. and Cerdan, A. H. and Sperandio, O.

Imbalance in chemical space: How to facilitate the identification of protein-protein interaction inhibitors

Sci Rep (2016)

6, 23815

10.1038/srep23815

Kuenemann, M. A. and Sperandio, O. and Labbe, C. M. and Lagorce, D. and Miteva, M. A. and Villoutreix, B. O.

In silico design of low molecular weight protein-protein interaction inhibitors: Overall concept and recent advances

Prog Biophys Mol Biol (2015)

119, 20-32

10.1016/j.pbiomolbio.2015.02.006

Kuhn, I. and Kellenberger, E. and Said-Hassane, F. and Villa, P. and Rognan, D. and Lobstein, A. and Haiech, J. and Hibert, M. and Schuber, F. and Muller-Steffner, H.

Identification by high-throughput screening of inhibitors of Schistosoma mansoni NAD(+) catabolizing enzyme

Bioorg Med Chem (2010)

18, 7900-10

10.1016/j.bmc.2010.09.041

Kumar, V. and Jolivalt, C. and Pulpytel, J. and Jafari, R. and Arefi-Khonsari, F.

Development of silver nanoparticle loaded antibacterial polymer mesh using plasma polymerization process

J Biomed Mater Res A (2013)

101, 1121-32

10.1002/jbm.a.34419

Labbe, C. M. and Kuenemann, M. A. and Zarzycka, B. and Vriend, G. and Nicolaes, G. A. and Lagorce, D. and Miteva, M. A. and Villoutreix, B. O. and Sperandio, O.

iPPI-DB: an online database of modulators of protein-protein interactions

Nucleic Acids Res (2016)

44, D542-7

10.1093/nar/gkv982

Labbe, C. M. and Laconde, G. and Kuenemann, M. A. and Villoutreix, B. O. and Sperandio, O.

iPPI-DB: a manually curated and interactive database of small non-peptide inhibitors of protein-protein interactions

Drug Discov Today (2013)

18, 958-68

10.1016/j.drudis.2013.05.003

Labbe, C. M. and Pencheva, T. and Jereva, D. and Desvillechabrol, D. and Becot, J. and Villoutreix, B. O. and Pajeva, I. and Miteva, M. A.

AMMOS2: a web server for protein-ligand-water complexes refinement via molecular mechanics

Nucleic Acids Res (2017)

45, W350-W355

10.1093/nar/gkx397

Labbe, C. M. and Rey, J. and Lagorce, D. and Vavrusa, M. and Becot, J. and Sperandio, O. and Villoutreix, B. O. and Tuffery, P. and Miteva, M. A.

MTiOpenScreen: a web server for structure-based virtual screening

Nucleic Acids Res (2015)

43, W448-54

10.1093/nar/gkv306

Labesse, G. and Alexandre, T. and Gelin, M. and Haouz, A. and Munier-Lehmann, H.

Crystallographic studies of two variants of Pseudomonas aeruginosa IMPDH with impaired allosteric regulation

Acta Crystallogr D Biol Crystallogr (2015)

71, 1890-9

10.1107/S1399004715013115

Labesse, G. and Alexandre, T. and Vaupre, L. and Salard-Arnaud, I. and Him, J. L. and Raynal, B. and Bron, P. and Munier-Lehmann, H.

MgATP regulates allostery and fiber formation in IMPDHs

Structure (2013)

21, 975-85

10.1016/j.str.2013.03.011

Labesse, G. and Benkali, K. and Salard-Arnaud, I. and Gilles, A. M. and Munier-Lehmann, H.

Structural and functional characterization of the Mycobacterium tuberculosis uridine monophosphate kinase: insights into the allosteric regulation

Nucleic Acids Res (2011)

39, 3458-72

10.1093/nar/gkq1250

Labriere, C. and Lozach, O. and Blairvacq, M. and Meijer, L. and Guillou, C.

Further investigation of Paprotrain: Towards the conception of selective and multi-targeted CNS kinase inhibitors

Eur J Med Chem (2016)

124, 920-934

10.1016/j.ejmech.2016.08.069

Lachkar, D. and Denizot, N. and Bernadat, G. and Ahamada, K. and Beniddir, M. A. and Dumontet, V. and Gallard, J. F. and Guillot, R. and Leblanc, K. and N'Nang E, O. and Turpin, V. and Kouklovsky, C. and Poupon, E. and Evanno, L. and Vincent, G.

Unified biomimetic assembly of voacalgine A and bipleiophylline via divergent oxidative couplings

Nat Chem (2017)

9, 793-798

10.1038/nchem.2735

Lacroix, D. and Prado, S. and Kamoga, D. and Kasenene, J. and Namukobe, J. and Krief, S. and Dumontet, V. and Mouray, E. and Bodo, B. and Brunois, F.

Antiplasmodial and cytotoxic activities of medicinal plants traditionally used in the village of Kiohima, Uganda

J Ethnopharmacol (2011)

133, 850-5

10.1016/j.jep.2010.11.013

Ladeveze, S. and Cioci, G. and Roblin, P. and Mourey, L. and Tranier, S. and Potocki-Veronese, G.

Structural bases for N-glycan processing by mannoside phosphorylase

Acta Crystallogr D Biol Crystallogr (2015)

71, 1335-46

10.1107/S1399004715006604

Lafanechere, L. and Job, D.

Preparation of pure tyrosinated or detyrosinated tubulin isoforms

Methods Mol Biol (2011)

777, 71-86

10.1007/978-1-61779-252-6_5

Lafanechere, L. and Marechal, E. and Guillemot, J. C.

[Chemical biology: cross-border strategies]

Med Sci (Paris) (2014)

30, 1059-60

10.1051/medsci/20143012001

Lafont, F. and Ayadi, N. and Charlier, C. and Weigel, P. and Nabiev, I. and Benhelli-Mokrani, H. and Fleury, F.

Assessment of DNA-PKcs kinase activity by quantum dot-based microarray

Sci Rep (2018)

8, 10968

10.1038/s41598-018-29256-2

Lagorce, D. and Bouslama, L. and Becot, J. and Miteva, M. A. and Villoutreix, B. O.

FAF-Drugs4: free ADME-tox filtering computations for chemical biology and early stages drug discovery

Bioinformatics (2017)

33, 3658-3660

10.1093/bioinformatics/btx491

Lagorce, D. and Douguet, D. and Miteva, M. A. and Villoutreix, B. O.

Computational analysis of calculated physicochemical and ADMET properties of protein-protein interaction inhibitors

Sci Rep (2017)

7, 46277

10.1038/srep46277

Lagorce, D. and Maupetit, J. and Baell, J. and Sperandio, O. and Tuffery, P. and Miteva, M. A. and Galons, H. and Villoutreix, B. O.

The FAF-Drugs2 server: a multistep engine to prepare electronic chemical compound collections

Bioinformatics (2011)

27, 2018-20

10.1093/bioinformatics/btr333

Lagorce, D. and Oliveira, N. and Miteva, M. A. and Villoutreix, B. O.

Pan-assay interference compounds (PAINS) that may not be too painful for chemical biology projects

Drug Discov Today (2017)

22, 1131-1133

10.1016/j.drudis.2017.05.017

Lagorce, D. and Sperandio, O. and Baell, J. B. and Miteva, M. A. and Villoutreix, B. O.

FAF-Drugs3: a web server for compound property calculation and chemical library design

Nucleic Acids Res (2015)

43, W200-7

10.1093/nar/gkv353

Lagorce, D. and Villoutreix, B. O. and Miteva, M. A.

Three-dimensional structure generators of drug-like compounds: DG-AMMOS, an open-source package

Expert Opin Drug Discov (2011)

6, 339-51

10.1517/17460441.2011.554393

Lagoutte, E. and Villeneuve, C. and Lafanechere, L. and Wells, C. M. and Jones, G. E. and Chavrier, P. and Rosse, C.

LIMK Regulates Tumor-Cell Invasion and Matrix Degradation Through Tyrosine Phosphorylation of MT1-MMP

Sci Rep (2016)

6, 24925

10.1038/srep24925

Lalut, J. and Karila, D. and Dallemagne, P. and Rochais, C.

Modulating 5-HT4 and 5-HT6 receptors in Alzheimer's disease treatment

Future Med Chem (2017)

9, 781-795

10.4155/fmc-2017-0031

Lalut, J. and Tournier, B. B. and Cailly, T. and Lecoutey, C. and Corvaisier, S. and Davis, A. and Ballandonne, C. and Since, M. and Millet, P. and Fabis, F. and Dallemagne, P. and Rochais, C.

Synthesis and evaluation of novel serotonin 4 receptor radiotracers for single photon emission computed tomography

Eur J Med Chem (2016)

116, 90-101

10.1016/j.ejmech.2016.03.059

Lamaa, D. and Lin, H. P. and Zig, L. and Bauvais, C. and Bollot, G. and Bignon, J. and Levaique, H. and Pamlard, O. and Dubois, J. and Ouaissi, M. and Souce, M. and Kasselouri, A. and Saller, F. and Borgel, D. and Jayat-Vignoles, C. and Al-Mouhammad, H. and Feuillard, J. and Benihoud, K. and Alami, M. and Hamze, A.

Design and Synthesis of Tubulin and Histone Deacetylase Inhibitor Based on iso-Combretastatin A-4

J Med Chem (2018)

61, 6574-6591

10.1021/acs.jmedchem.8b00050

Lamiable, A. and Thevenet, P. and Eustache, S. and Saladin, A. and Moroy, G. and Tuffery, P.

Peptide Suboptimal Conformation Sampling for the Prediction of Protein-Peptide Interactions

Methods Mol Biol (2017)

1561, 21-34

10.1007/978-1-4939-6798-8_3

Lamiable, A. and Thevenet, P. and Rey, J. and Vavrusa, M. and Derreumaux, P. and Tuffery, P.

PEP-FOLD3: faster de novo structure prediction for linear peptides in solution and in complex

Nucleic Acids Res (2016)

44, W449-54

10.1093/nar/gkw329

Landes, T. and Emorine, L. J. and Courilleau, D. and Rojo, M. and Belenguer, P. and Arnaune-Pelloquin, L.

The BH3-only Bnip3 binds to the dynamin Opa1 to promote mitochondrial fragmentation and apoptosis by distinct mechanisms

EMBO Rep (2010)

11, 459-65

10.1038/embor.2010.50

Landes, T. and Leroy, I. and Bertholet, A. and Diot, A. and Khosrobakhsh, F. and Daloyau, M. and Davezac, N. and Miquel, M. C. and Courilleau, D. and Guillou, E. and Olichon, A. and Lenaers, G. and Arnaune-Pelloquin, L. and Emorine, L. J. and Belenguer, P.

OPA1 (dys)functions

Semin Cell Dev Biol (2010)

21, 593-8

10.1016/j.semcdb.2009.12.012

Lange, A. and Ismail, M. B. and Riviere, G. and Hologne, M. and Lacabanne, D. and Guilliere, F. and Lancelin, J. M. and Krimm, I. and Walker, O.

Competitive binding of UBPY and ubiquitin to the STAM2 SH3 domain revealed by NMR

FEBS Lett (2012)

586, 3379-84

10.1016/j.febslet.2012.07.047

Larchanche, P. E. and Ultre, V. and Le Broc, D. and Ballandone, C. and Furman, C. and Dallemagne, P. and Melnyk, P. and Carato, P.

6-Sulfonylbenzothiazolones as potential scaffolds for the design of 5-HT6 ligands

Eur J Med Chem (2015)

92, 807-17

10.1016/j.ejmech.2015.01.052

Lasalle, M. and Hoguet, V. and Hennuyer, N. and Leroux, F. and Piveteau, C. and Belloy, L. and Lestavel, S. and Vallez, E. and Dorchies, E. and Duplan, I. and Sevin, E. and Culot, M. and Gosselet, F. and Boulahjar, R. and Herledan, A. and Staels, B. and Deprez, B. and Tailleux, A. and Charton, J.

Topical Intestinal Aminoimidazole Agonists of G-Protein-Coupled Bile Acid Receptor 1 Promote Glucagon Like Peptide-1 Secretion and Improve Glucose Tolerance

J Med Chem (2017)

60, 4185-4211

10.1021/acs.jmedchem.6b01873

Laskaris, P. and Atrouni, A. and Calera, J. A. and d'Enfert, C. and Munier-Lehmann, H. and Cavaillon, J. M. and Latge, J. P. and Ibrahim-Granet, O.

Administration of Zinc Chelators Improves Survival of Mice Infected with Aspergillus fumigatus both in Monotherapy and in Combination with Caspofungin

Antimicrob Agents Chemother (2016)

60, 5631-9

10.1128/AAC.00324-16

Laskaris, P. and Vicentefranqueira, R. and Helynck, O. and Jouvion, G. and Calera, J. A. and du Merle, L. and Suzenet, F. and Buron, F. and de Sousa, R. A. and Mansuy, D. and Cavaillon, J. M. and Latge, J. P. and Munier-Lehmann, H. and Ibrahim-Granet, O.

A Novel Polyaminocarboxylate Compound To Treat Murine Pulmonary Aspergillosis by Interfering with Zinc Metabolism

Antimicrob Agents Chemother (2018)

62,

10.1128/AAC.02510-17

Lasserre, J. P. and Dautant, A. and Aiyar, R. S. and Kucharczyk, R. and Glatigny, A. and Tribouillard-Tanvier, D. and Rytka, J. and Blondel, M. and Skoczen, N. and Reynier, P. and Pitayu, L. and Rotig, A. and Delahodde, A. and Steinmetz, L. M. and Dujardin, G. and Procaccio, V. and di Rago, J. P.

Yeast as a system for modeling mitochondrial disease mechanisms and discovering therapies

Dis Model Mech (2015)

8, 509-26

10.1242/dmm.020438

Laurent, M. A. and Bonnier, D. and Theret, N. and Tuffery, P. and Moroy, G.

In silico characterization of the interaction between LSKL peptide, a LAP-TGF-beta derived peptide, and ADAMTS1

Comput Biol Chem (2016)

61, 155-61

10.1016/j.compbiolchem.2016.01.012

Laux, W. H. and Priet, S. and Alvarez, K. and Peyrottes, S. and Perigaud, C.

Synthesis and substrate properties towards HIV-1 reverse transcriptase of new diphosphate analogues of 9-[(2-phosphonomethoxy)ethyl]adenine

Antivir Chem Chemother (2018)

26, 2040206618757636

10.1177/2040206618757636

Lavaud, P. and Gravis, G. and Foulon, S. and Joly, F. and Oudard, S. and Priou, F. and Latorzeff, I. and Mourey, L. and Soulie, M. and Delva, R. and Krakowski, I. and Laguerre, B. and Theodore, C. and Ferrero, J. M. and Beuzeboc, P. and Habibian, M. and Rolland, F. and Deplanque, G. and Pouessel, D. and Zanetta, S. and Berdah, J. F. and Dauba, J. and Baciuchka, M. and Platini, C. and Linassier, C. and Tubiana-Mathieu, N. and Machiels, J. P. and Kouri, C. E. and Ravaud, A. and Suc, E. and Eymard, J. C. and Hasbini, A. and Bousquet, G. and Culine, S. and Boher, J. M. and Tergemina-Clain, G. and Legoupil, C. and Fizazi, K.

Anticancer Activity and Tolerance of Treatments Received Beyond Progression in Men Treated Upfront with Androgen Deprivation Therapy With or Without Docetaxel for Metastatic Castration-naive Prostate Cancer in the GETUG-AFU 15 Phase 3 Trial

Eur Urol (2018)

73, 696-703

10.1016/j.eururo.2017.09.022

Laventie, B. J. and Guerin, F. and Mourey, L. and Tawk, M. Y. and Jover, E. and Maveyraud, L. and Prevost, G.

Residues essential for Panton-Valentine leukocidin S component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface

PLoS One (2014)

9, e92094

10.1371/journal.pone.0092094

Lawson, M. and Rodrigo, J. and Baratte, B. and Robert, T. and Delehouze, C. and Lozach, O. and Ruchaud, S. and Bach, S. and Brion, J. D. and Alami, M. and Hamze, A.

Synthesis, biological evaluation and molecular modeling studies of imidazo[1,2-a]pyridines derivatives as protein kinase inhibitors

Eur J Med Chem (2016)

123, 105-114

10.1016/j.ejmech.2016.07.040

Le Cann, F. and Delehouze, C. and Leverrier-Penna, S. and Filliol, A. and Comte, A. and Delalande, O. and Desban, N. and Baratte, B. and Gallais, I. and Piquet-Pellorce, C. and Faurez, F. and Bonnet, M. and Mettey, Y. and Goekjian, P. and Samson, M. and Vandenabeele, P. and Bach, S. and Dimanche-Boitrel, M. T.

Sibiriline, a new small chemical inhibitor of receptor-interacting protein kinase 1, prevents immune-dependent hepatitis

FEBS J (2017)

284, 3050-3068

10.1111/febs.14176

Masse, N. and Davidson, A. and Ferron, F. and Alvarez, K. and Jacobs, M. and Romette, J. L. and Canard, B. and Guillemot, J. C.

Dengue virus replicons: production of an interserotypic chimera and cell lines from different species, and establishment of a cell-based fluorescent assay to screen inhibitors, validated by the evaluation of ribavirin's activity

Antiviral Res (2010)

86, 296-305

10.1016/j.antiviral.2010.03.010

Mathieu, A. L. and Sperandio, O. and Pottiez, V. and Balzarin, S. and Herledan, A. and Elkaim, J. O. and Fogeron, M. L. and Piveteau, C. and Dassonneville, S. and Deprez, B. and Villoutreix, B. O. and Bonnefoy, N. and Leroux, F.

Identification of Small Inhibitory Molecules Targeting the Bfl-1 Anti-Apoptotic Protein That Alleviates Resistance to ABT-737

J Biomol Screen (2014)

19, 1035-46

10.1177/1087057114534070

Mathieu, S. and Cisse, C. and Vitale, S. and Ahmadova, A. and Degardin, M. and Perard, J. and Colas, P. and Miras, R. and Boturyn, D. and Coves, J. and Crouzy, S. and Michaud-Soret, I.

From Peptide Aptamers to Inhibitors of FUR, Bacterial Transcriptional Regulator of Iron Homeostasis and Virulence

ACS Chem Biol (2016)

11, 2519-28

10.1021/acschembio.6b00360

Mathis, C. and Bott, J. B. and Candusso, M. P. and Simonin, F. and Cassel, J. C.

Impaired striatum-dependent behavior in GASP-1-knock-out mice

Genes Brain Behav (2011)

10, 299-308

10.1111/j.1601-183X.2010.00666.x

Matuszewski, L. and Perdriolle-Galet, E. and Clerc-Urmes, I. and Bach-Segura, P. and Klein, O. and Masutti, J. P. and Morel, O.

[Prenatal diagnosis of neural tube defects: Correlation between prenatal and postnatal data]

J Gynecol Obstet Hum Reprod (2017)

46, 291-296

10.1016/j.jogoh.2016.10.009

Matviiuk, T. and Madacki, J. and Mori, G. and Orena, B. S. and Menendez, C. and Kysil, A. and Andre-Barres, C. and Rodriguez, F. and Kordulakova, J. and Mallet-Ladeira, S. and Voitenko, Z. and Pasca, M. R. and Lherbet, C. and Baltas, M.

Pyrrolidinone and pyrrolidine derivatives: Evaluation as inhibitors of InhA and Mycobacterium tuberculosis

Eur J Med Chem (2016)

123, 462-475

10.1016/j.ejmech.2016.07.028

Matviiuk, T. and Mori, G. and Lherbet, C. and Rodriguez, F. and Pasca, M. R. and Gorichko, M. and Guidetti, B. and Voitenko, Z. and Baltas, M.

Synthesis of 3-heteryl substituted pyrrolidine-2,5-diones via catalytic Michael reaction and evaluation of their inhibitory activity against InhA and Mycobacterium tuberculosis

Eur J Med Chem (2014)

71, 46-52

10.1016/j.ejmech.2013.10.069

Matviiuk, T. and Rodriguez, F. and Saffon, N. and Mallet-Ladeira, S. and Gorichko, M. and de Jesus Lopes Ribeiro, A. L. and Pasca, M. R. and Lherbet, C. and Voitenko, Z. and Baltas, M.

Design, chemical synthesis of 3-(9H-fluoren-9-yl)pyrrolidine-2,5-dione derivatives and biological activity against enoyl-ACP reductase (InhA) and Mycobacterium tuberculosis

Eur J Med Chem (2013)

70, 37-48

10.1016/j.ejmech.2013.09.041

Maupetit, J. and Derreumaux, P. and Tuffery, P.

A fast method for large-scale de novo peptide and miniprotein structure prediction

J Comput Chem (2010)

31, 726-38

10.1002/jcc.21365

Maurent, K. and Vanucci-Bacque, C. and Baltas, M. and Negre-Salvayre, A. and Auge, N. and Bedos-Belval, F.

Synthesis and biological evaluation of diarylheptanoids as potential antioxidant and anti-inflammatory agents

Eur J Med Chem (2018)

144, 289-299

10.1016/j.ejmech.2017.12.033

Maurent, K. and Vanucci-Bacque, C. and Saffon-Merceron, N. and Baltas, M. and Bedos-Belval, F.

Total Synthesis of Tedarene A

J Nat Prod (2017)

80, 1623-1630

10.1021/acs.jnatprod.7b00199

Mayola, E. and Gallerne, C. and Esposti, D. D. and Martel, C. and Pervaiz, S. and Larue, L. and Debuire, B. and Lemoine, A. and Brenner, C. and Lemaire, C.

Withaferin A induces apoptosis in human melanoma cells through generation of reactive oxygen species and down-regulation of Bcl-2

Apoptosis (2011)

16, 1014-27

10.1007/s10495-011-0625-x

Mbatchi, L. C. and Gassiot, M. and Pourquier, P. and Goberna, A. and Mahammedi, H. and Mourey, L. and Joly, F. and Lumbroso, S. and Evrard, A. and Houede, N.

Association of NR1I2, CYP3A5 and ABCB1 genetic polymorphisms with variability of temsirolimus pharmacokinetics and toxicity in patients with metastatic bladder cancer

Cancer Chemother Pharmacol (2017)

80, 653-659

10.1007/s00280-017-3379-5

Meijer, L. and Nelson, D. J. and Riazanski, V. and Gabdoulkhakova, A. G. and Hery-Arnaud, G. and Le Berre, R. and Loaec, N. and Oumata, N. and Galons, H. and Nowak, E. and Gueganton, L. and Dorothee, G. and Prochazkova, M. and Hall, B. and Kulkarni, A. B. and Gray, R. D. and Rossi, A. G. and Witko-Sarsat, V. and Norez, C. and Becq, F. and Ravel, D. and Mottier, D. and Rault, G.

Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis

J Innate Immun (2016)

8, 330-49

10.1159/000444256

Lefebvre, J. and Muharram, G. and Leroy, C. and Kherrouche, Z. and Montagne, R. and Ichim, G. and Tauszig-Delamasure, S. and Chotteau-Lelievre, A. and Brenner, C. and Mehlen, P. and Tulasne, D.

Caspase-generated fragment of the Met receptor favors apoptosis via the intrinsic pathway independently of its tyrosine kinase activity

Cell Death Dis (2013)

4, e871

10.1038/cddis.2013.377

Legendre, M. and Alavi, S. M. and Dzyuba, B. and Linhart, O. and Prokopchuk, G. and Cochet, C. and Dugue, R. and Cosson, J.

Adaptations of semen characteristics and sperm motility to harsh salinity: Extreme situations encountered by the euryhaline tilapia Sarotherodon melanotheron heudelotii (Dumeril, 1859)

Theriogenology (2016)

86, 1251-67

10.1016/j.theriogenology.2016.04.066

Leite Nascimento, T. and Hillaireau, H. and Vergnaud, J. and Rivano, M. and Delomenie, C. and Courilleau, D. and Arpicco, S. and Suk, J. S. and Hanes, J. and Fattal, E.

Hyaluronic acid-conjugated lipoplexes for targeted delivery of siRNA in a murine metastatic lung cancer model

Int J Pharm (2016)

514, 103-111

10.1016/j.ijpharm.2016.06.125

Letronne, F. and Laumet, G. and Ayral, A. M. and Chapuis, J. and Demiautte, F. and Laga, M. and Vandenberghe, M. E. and Malmanche, N. and Leroux, F. and Eysert, F. and Sottejeau, Y. and Chami, L. and Flaig, A. and Bauer, C. and Dourlen, P. and Lesaffre, M. and Delay, C. and Huot, L. and Dumont, J. and Werkmeister, E. and Lafont, F. and Mendes, T. and Hansmannel, F. and Dermaut, B. and Deprez, B. and Herard, A. S. and Dhenain, M. and Souedet, N. and Pasquier, F. and Tulasne, D. and Berr, C. and Hauw, J. J. and Lemoine, Y. and Amouyel, P. and Mann, D. and Deprez, R. and Checler, F. and Hot, D. and Delzescaux, T. and Gevaert, K. and Lambert, J. C.

ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimer's Disease

EBioMedicine (2016)

9, 278-292

10.1016/j.ebiom.2016.06.002

Levoye, A. and Zwier, J. M. and Jaracz-Ros, A. and Klipfel, L. and Cottet, M. and Maurel, D. and Bdioui, S. and Balabanian, K. and Prezeau, L. and Trinquet, E. and Durroux, T. and Bachelerie, F.

A Broad G Protein-Coupled Receptor Internalization Assay that Combines SNAP-Tag Labeling, Diffusion-Enhanced Resonance Energy Transfer, and a Highly Emissive Terbium Cryptate

Front Endocrinol (Lausanne) (2015)

6, 167

10.3389/fendo.2015.00167

Levy-Bimbot, M. and Major, G. and Courilleau, D. and Blondeau, J. P. and Levi, Y.

Tetrabromobisphenol-A disrupts thyroid hormone receptor alpha function in vitro: use of fluorescence polarization to assay corepressor and coactivator peptide binding

Chemosphere (2012)

87, 782-8

10.1016/j.chemosphere.2011.12.080

Lewin, G. and Aubert, G. and Thoret, S. and Dubois, J. and Cresteil, T.

Influence of the skeleton on the cytotoxicity of flavonoids

Bioorg Med Chem (2012)

20, 1231-9

10.1016/j.bmc.2011.12.038

Lewin, G. and Maciuk, A. and Thoret, S. and Aubert, G. and Dubois, J. and Cresteil, T.

Semisynthesis of natural flavones inhibiting tubulin polymerization, from hesperidin

J Nat Prod (2010)

73, 702-6

10.1021/np100065v

Lewin, G. and Shridhar, N. B. and Aubert, G. and Thoret, S. and Dubois, J. and Cresteil, T.

Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk

Bioorg Med Chem (2011)

19, 186-96

10.1016/j.bmc.2010.11.035

Li, C. and Debing, Y. and Jankevicius, G. and Neyts, J. and Ahel, I. and Coutard, B. and Canard, B.

Viral Macro Domains Reverse Protein ADP-Ribosylation

J Virol (2016)

90, 8478-86

10.1128/JVI.00705-16

Li, C. and Guillen, J. and Rabah, N. and Blanjoie, A. and Debart, F. and Vasseur, J. J. and Canard, B. and Decroly, E. and Coutard, B.

mRNA Capping by Venezuelan Equine Encephalitis Virus nsP1: Functional Characterization and Implications for Antiviral Research

J Virol (2015)

89, 8292-303

10.1128/JVI.00599-15

Liger, F. and Bouhours, P. and Ganem-Elbaz, C. and Jolivalt, C. and Pellet-Rostaing, S. and Popowycz, F. and Paris, J. M. and Lemaire, M.

C2 Arylated Benzo[b]thiophene Derivatives as Staphylococcus aureus NorA Efflux Pump Inhibitors

ChemMedChem (2016)

11, 320-30

10.1002/cmdc.201500463

Lima, C. R. and Carels, N. and Guimaraes, A. C. and Tuffery, P. and Derreumaux, P.

In silico structural characterization of protein targets for drug development against Trypanosoma cruzi

J Mol Model (2016)

22, 244

10.1007/s00894-016-3115-9

Lin, A. and Horvath, D. and Afonina, V. and Marcou, G. and Reymond, J. L. and Varnek, A.

Mapping of the Available Chemical Space versus the Chemical Universe of Lead-Like Compounds

ChemMedChem (2018)

13, 540-554

10.1002/cmdc.201700561

Lin, A. I. and Madzhidov, T. I. and Klimchuk, O. and Nugmanov, R. I. and Antipin, I. S. and Varnek, A.

Automatized Assessment of Protective Group Reactivity: A Step Toward Big Reaction Data Analysis

J Chem Inf Model (2016)

56, 2140-2148

10.1021/acs.jcim.6b00319

Lindstrom, L. and Villoutreix, B. O. and Lehn, S. and Hellsten, R. and Nilsson, E. and Crneta, E. and Olsson, R. and Alvarado-Kristensson, M.

Therapeutic Targeting of Nuclear gamma-Tubulin in RB1-Negative Tumors

Mol Cancer Res (2015)

13, 1073-82

10.1158/1541-7786.MCR-15-0063-T

Lionnard, L. and Duc, P. and Brennan, M. S. and Kueh, A. J. and Pal, M. and Guardia, F. and Mojsa, B. and Damiano, M. A. and Mora, S. and Lassot, I. and Ravichandran, R. and Cochet, C. and Aouacheria, A. and Potts, P. R. and Herold, M. J. and Desagher, S. and Kucharczak, J.

TRIM17 and TRIM28 antagonistically regulate the ubiquitination and anti-apoptotic activity of BCL2A1

Cell Death Differ (2018)

,

10.1038/s41418-018-0169-5

Lista, M. J. and Martins, R. P. and Angrand, G. and Quillevere, A. and Daskalogianni, C. and Voisset, C. and Teulade-Fichou, M. P. and Fahraeus, R. and Blondel, M.

A yeast model for the mechanism of the Epstein-Barr virus immune evasion identifies a new therapeutic target to interfere with the virus stealthiness

Microb Cell (2017)

4, 305-307

10.15698/mic2017.09.590

Lista, M. J. and Martins, R. P. and Billant, O. and Contesse, M. A. and Findakly, S. and Pochard, P. and Daskalogianni, C. and Beauvineau, C. and Guetta, C. and Jamin, C. and Teulade-Fichou, M. P. and Fahraeus, R. and Voisset, C. and Blondel, M.

Nucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNA

Nat Commun (2017)

8, 16043

10.1038/ncomms16043

Lista, M. J. and Voisset, C. and Contesse, M. A. and Friocourt, G. and Daskalogianni, C. and Bihel, F. and Fahraeus, R. and Blondel, M.

The long-lasting love affair between the budding yeast Saccharomyces cerevisiae and the Epstein-Barr virus

Biotechnol J (2015)

10, 1670-81

10.1002/biot.201500161

Listunov, D. and Fabing, I. and Saffon-Merceron, N. and Gaspard, H. and Volovenko, Y. and Maraval, V. and Chauvin, R. and Genisson, Y.

Asymmetric synthesis and biological evaluation of natural or bioinspired cytotoxic C2-symmetrical lipids with two terminal chiral alkynylcarbinol pharmacophores

J Org Chem (2015)

80, 5386-94

10.1021/acs.joc.5b00494

Listunov, D. and Joly, E. and Duhayon, C. and Saffon-Merceron, N. and Fabing, I. and Genisson, Y. and Maraval, V. and Chauvin, R.

Methinylogation Approach in Chiral Pharmacophore Design: from Alkynyl- to Allenyl-carbinol Warheads against Tumor Cells

ChemMedChem (2018)

,

10.1002/cmdc.201800284

Listunov, D. and Maraval, V. and Chauvin, R. and Genisson, Y.

Chiral alkynylcarbinols from marine sponges: asymmetric synthesis and biological relevance

Nat Prod Rep (2015)

32, 49-75

10.1039/c4np00043a

Listunov, D. and Mazeres, S. and Volovenko, Y. and Joly, E. and Genisson, Y. and Maraval, V. and Chauvin, R.

Fluorophore-tagged pharmacophores for antitumor cytotoxicity: Modified chiral lipidic dialkynylcarbinols for cell imaging

Bioorg Med Chem Lett (2015)

25, 4652-6

10.1016/j.bmcl.2015.08.029

Liu, H. and Audisio, D. and Plougastel, L. and Decuypere, E. and Buisson, D. A. and Koniev, O. and Kolodych, S. and Wagner, A. and Elhabiri, M. and Krzyczmonik, A. and Forsback, S. and Solin, O. and Gouverneur, V. and Taran, F.

Ultrafast Click Chemistry with Fluorosydnones

Angew Chem Int Ed Engl (2016)

55, 12073-7

10.1002/anie.201606495

Liu, J. and Zhang, Z. and Moreno-Delgado, D. and Dalton, J. A. and Rovira, X. and Trapero, A. and Goudet, C. and Llebaria, A. and Giraldo, J. and Yuan, Q. and Rondard, P. and Huang, S. and Liu, J. and Pin, J. P.

Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer

Elife (2017)

6,

10.7554/eLife.26985

Loeuillet, C. and Touquet, B. and Oury, B. and Eddaikra, N. and Pons, J. L. and Guichou, J. F. and Labesse, G. and Sereno, D.

Synthesis of aminophenylhydroxamate and aminobenzylhydroxamate derivatives and in vitro screening for antiparasitic and histone deacetylase inhibitory activity

Int J Parasitol Drugs Drug Resist (2018)

8, 59-66

10.1016/j.ijpddr.2018.01.002

Logez, C. and Berger, S. and Legros, C. and Baneres, J. L. and Cohen, W. and Delagrange, P. and Nosjean, O. and Boutin, J. A. and Ferry, G. and Simonin, F. and Wagner, R.

Recombinant human melatonin receptor MT1 isolated in mixed detergents shows pharmacology similar to that in mammalian cell membranes

PLoS One (2014)

9, e100616

10.1371/journal.pone.0100616

Loidreau, Y. and Marchand, P. and Dubouilh-Benard, C. and Nourrisson, M. R. and Duflos, M. and Lozach, O. and Loaec, N. and Meijer, L. and Besson, T.

Synthesis and biological evaluation of N-arylbenzo[b]thieno[3,2-d]pyrimidin-4-amines and their pyrido and pyrazino analogues as Ser/Thr kinase inhibitors

Eur J Med Chem (2012)

58, 171-83

10.1016/j.ejmech.2012.10.006

Loison, S. and Cottet, M. and Orcel, H. and Adihou, H. and Rahmeh, R. and Lamarque, L. and Trinquet, E. and Kellenberger, E. and Hibert, M. and Durroux, T. and Mouillac, B. and Bonnet, D.

Selective fluorescent nonpeptidic antagonists for vasopressin V(2) GPCR: application to ligand screening and oligomerization assays

J Med Chem (2012)

55, 8588-602

10.1021/jm3006146

Lome, V. and Brunel, J. M. and Pages, J. M. and Bolla, J. M.

Multiparametric Profiling for Identification of Chemosensitizers against Gram-Negative Bacteria

Front Microbiol (2018)

9, 204

10.3389/fmicb.2018.00204

Longeon, A. and Copp, B. R. and Quevrain, E. and Roue, M. and Kientz, B. and Cresteil, T. and Petek, S. and Debitus, C. and Bourguet-Kondracki, M. L.

Bioactive indole derivatives from the South Pacific marine sponges Rhopaloeides odorabile and Hyrtios sp

Mar Drugs (2011)

9, 879-88

10.3390/md9050879

Lopez-Ramos, M. and Prudent, R. and Moucadel, V. and Sautel, C. F. and Barette, C. and Lafanechere, L. and Mouawad, L. and Grierson, D. and Schmidt, F. and Florent, J. C. and Filippakopoulos, P. and Bullock, A. N. and Knapp, S. and Reiser, J. B. and Cochet, C.

New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights

FASEB J (2010)

24, 3171-85

10.1096/fj.09-143743

Louet, M. and Bitam, S. and Bakouh, N. and Bignon, Y. and Planelles, G. and Lagorce, D. and Miteva, M. A. and Eladari, D. and Teulon, J. and Villoutreix, B. O.

In silico model of the human ClC-Kb chloride channel: pore mapping, biostructural pathology and drug screening

Sci Rep (2017)

7, 7249

10.1038/s41598-017-07794-5

Louet, M. and Labbe, C. M. and Fagnen, C. and Aono, C. M. and Homem-de-Mello, P. and Villoutreix, B. O. and Miteva, M. A.

Insights into molecular mechanisms of drug metabolism dysfunction of human CYP2C9*30

PLoS One (2018)

13, e0197249

10.1371/journal.pone.0197249

Lucas-Hourani, M. and Dauzonne, D. and Jorda, P. and Cousin, G. and Lupan, A. and Helynck, O. and Caignard, G. and Janvier, G. and Andre-Leroux, G. and Khiar, S. and Escriou, N. and Despres, P. and Jacob, Y. and Munier-Lehmann, H. and Tangy, F. and Vidalain, P. O.

Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity

PLoS Pathog (2013)

9, e1003678

10.1371/journal.ppat.1003678

Lucas-Hourani, M. and Dauzonne, D. and Munier-Lehmann, H. and Khiar, S. and Nisole, S. and Dairou, J. and Helynck, O. and Afonso, P. V. and Tangy, F. and Vidalain, P. O.

Original Chemical Series of Pyrimidine Biosynthesis Inhibitors That Boost the Antiviral Interferon Response

Antimicrob Agents Chemother (2017)

61,

10.1128/AAC.00383-17

Lucas-Hourani, M. and Lupan, A. and Despres, P. and Thoret, S. and Pamlard, O. and Dubois, J. and Guillou, C. and Tangy, F. and Vidalain, P. O. and Munier-Lehmann, H.

A phenotypic assay to identify Chikungunya virus inhibitors targeting the nonstructural protein nsP2

J Biomol Screen (2013)

18, 172-9

10.1177/1087057112460091

Lucas-Hourani, M. and Munier-Lehmann, H. and El Mazouni, F. and Malmquist, N. A. and Harpon, J. and Coutant, E. P. and Guillou, S. and Helynck, O. and Noel, A. and Scherf, A. and Phillips, M. A. and Tangy, F. and Vidalain, P. O. and Janin, Y. L.

Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH)

J Med Chem (2015)

58, 5579-98

10.1021/acs.jmedchem.5b00606

Lugari, A. and Betzi, S. and Decroly, E. and Bonnaud, E. and Hermant, A. and Guillemot, J. C. and Debarnot, C. and Borg, J. P. and Bouvet, M. and Canard, B. and Morelli, X. and Lecine, P.

Molecular mapping of the RNA Cap 2'-O-methyltransferase activation interface between severe acute respiratory syndrome coronavirus nsp10 and nsp16

J Biol Chem (2010)

285, 33230-41

10.1074/jbc.M110.120014

Lugari, A. and Breuer, S. and Coursindel, T. and Opi, S. and Restouin, A. and Shi, X. and Nazabal, A. and Torbett, B. E. and Martinez, J. and Collette, Y. and Parrot, I. and Arold, S. T. and Morelli, X.

A specific protein disorder catalyzer of HIV-1 Nef

Bioorg Med Chem (2011)

19, 7401-6

10.1016/j.bmc.2011.10.051

Luzhkov, V. and Decroly, E. and Canard, B. and Selisko, B. and Aqvist, J.

Evaluation of Adamantane Derivatives as Inhibitors of Dengue Virus mRNA Cap Methyltransferase by Docking and Molecular Dynamics Simulations

Mol Inform (2013)

32, 155-64

10.1002/minf.201200107

Machelart, A. and Song, O. R. and Hoffmann, E. and Brodin, P.

Host-directed therapies offer novel opportunities for the fight against tuberculosis

Drug Discov Today (2017)

22, 1250-1257

10.1016/j.drudis.2017.05.005

Madonna, S. and Beclin, C. and Laras, Y. and Moret, V. and Marcowycz, A. and Lamoral-Theys, D. and Dubois, J. and Barthelemy-Requin, M. and Lenglet, G. and Depauw, S. and Cresteil, T. and Aubert, G. and Monnier, V. and Kiss, R. and David-Cordonnier, M. H. and Kraus, J. L.

Structure-activity relationships and mechanism of action of antitumor bis 8-hydroxyquinoline substituted benzylamines

Eur J Med Chem (2010)

45, 623-38

10.1016/j.ejmech.2009.11.006

Magnan, R. and Escrieut, C. and Gigoux, V. and De, K. and Clerc, P. and Niu, F. and Azema, J. and Masri, B. and Cordomi, A. and Baltas, M. and Tikhonova, I. G. and Fourmy, D.

Distinct CCK-2 receptor conformations associated with beta-arrestin-2 recruitment or phospholipase-C activation revealed by a biased antagonist

J Am Chem Soc (2013)

135, 2560-73

10.1021/ja308784w

Mahtal, N. and Brewee, C. and Pichard, S. and Visvikis, O. and Cintrat, J. C. and Barbier, J. and Lemichez, E. and Gillet, D.

Screening of a Drug Library Identifies Inhibitors of Cell Intoxication by CNF1

ChemMedChem (2018)

13, 754-761

10.1002/cmdc.201700631

Mai, H. L. and Grellier, P. and Prost, E. and Lemoine, P. and Poullain, C. and Dumontet, V. and Deguin, B. and Vo, T. B. H. and Michel, S. and Grougnet, R.

Triterpenes from the exudate of Gardenia urvillei

Phytochemistry (2016)

122, 193-202

10.1016/j.phytochem.2015.11.001

Mai, L. H. and Chabot, G. G. and Grellier, P. and Quentin, L. and Dumontet, V. and Poulain, C. and Espindola, L. S. and Michel, S. and Vo, H. T. and Deguin, B. and Grougnet, R.

Antivascular and anti-parasite activities of natural and hemisynthetic flavonoids from New Caledonian Gardenia species (Rubiaceae)

Eur J Med Chem (2015)

93, 93-100

10.1016/j.ejmech.2015.01.012

Mailly, L. and Xiao, F. and Lupberger, J. and Wilson, G. K. and Aubert, P. and Duong, F. H. T. and Calabrese, D. and Leboeuf, C. and Fofana, I. and Thumann, C. and Bandiera, S. and Lutgehetmann, M. and Volz, T. and Davis, C. and Harris, H. J. and Mee, C. J. and Girardi, E. and Chane-Woon-Ming, B. and Ericsson, M. and Fletcher, N. and Bartenschlager, R. and Pessaux, P. and Vercauteren, K. and Meuleman, P. and Villa, P. and Kaderali, L. and Pfeffer, S. and Heim, M. H. and Neunlist, M. and Zeisel, M. B. and Dandri, M. and McKeating, J. A. and Robinet, E. and Baumert, T. F.

Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody

Nat Biotechnol (2015)

33, 549-554

10.1038/nbt.3179

Maingot, L. and Elbakali, J. and Dumont, J. and Bosc, D. and Cousaert, N. and Urban, A. and Deglane, G. and Villoutreix, B. and Nagase, H. and Sperandio, O. and Leroux, F. and Deprez, B. and Deprez-Poulain, R.

Aggrecanase-2 inhibitors based on the acylthiosemicarbazide zinc-binding group

Eur J Med Chem (2013)

69, 244-61

10.1016/j.ejmech.2013.08.027

Maingot, L. and Leroux, F. and Landry, V. and Dumont, J. and Nagase, H. and Villoutreix, B. and Sperandio, O. and Deprez-Poulain, R. and Deprez, B.

New non-hydroxamic ADAMTS-5 inhibitors based on the 1,2,4-triazole-3-thiol scaffold

Bioorg Med Chem Lett (2010)

20, 6213-6

10.1016/j.bmcl.2010.08.108

Malik, G. and Ferry, A. and Guinchard, X. and Cresteil, T. and Crich, D.

N-O bond as a glycosidic-bond surrogate: synthetic studies toward polyhydroxylated N-alkoxypiperidines

Chemistry (2013)

19, 2168-79

10.1002/chem.201202374

Manes, G. and Meunier, I. and Avila-Fernandez, A. and Banfi, S. and Le Meur, G. and Zanlonghi, X. and Corton, M. and Simonelli, F. and Brabet, P. and Labesse, G. and Audo, I. and Mohand-Said, S. and Zeitz, C. and Sahel, J. A. and Weber, M. and Dollfus, H. and Dhaenens, C. M. and Allorge, D. and De Baere, E. and Koenekoop, R. K. and Kohl, S. and Cremers, F. P. and Hollyfield, J. G. and Senechal, A. and Hebrard, M. and Bocquet, B. and Ayuso Garcia, C. and Hamel, C. P.

Mutations in IMPG1 cause vitelliform macular dystrophies

Am J Hum Genet (2013)

93, 571-8

10.1016/j.ajhg.2013.07.018

Mani, L. and Jullian, V. and Mourkazel, B. and Valentin, A. and Dubois, J. and Cresteil, T. and Folcher, E. and Hooper, J. N. and Erpenbeck, D. and Aalbersberg, W. and Debitus, C.

New antiplasmodial bromotyrosine derivatives from Suberea ianthelliformis Lendenfeld, 1888

Chem Biodivers (2012)

9, 1436-51

10.1002/cbdv.201100309

Marchand, P. and Bazin, M. A. and Pagniez, F. and Riviere, G. and Bodero, L. and Marhadour, S. and Nourrisson, M. R. and Picot, C. and Ruchaud, S. and Bach, S. and Baratte, B. and Sauvain, M. and Pareja, D. C. and Vaisberg, A. J. and Le Pape, P.

Synthesis, antileishmanial activity and cytotoxicity of 2,3-diaryl- and 2,3,8-trisubstituted imidazo[1,2-a]pyrazines

Eur J Med Chem (2015)

103, 381-95

10.1016/j.ejmech.2015.09.002

Marcou, G. and Aires de Sousa, J. and Latino, D. A. and de Luca, A. and Horvath, D. and Rietsch, V. and Varnek, A.

Expert system for predicting reaction conditions: the Michael reaction case

J Chem Inf Model (2015)

55, 239-50

10.1021/ci500698a

Marcou, G. and Delouis, G. and Mokshyna, O. and Horvath, D. and Lachiche, N. and Varnek, A.

Transductive Ridge Regression in Structure-activity Modeling

Mol Inform (2018)

37,

10.1002/minf.201700112

Marcou, G. and Horvath, D. and Solov'ev, V. and Arrault, A. and Vayer, P. and Varnek, A.

Interpretability of SAR/QSAR Models of any Complexity by Atomic Contributions

Mol Inform (2012)

31, 639-42

10.1002/minf.201100136

Marcou, G. and Horvath, D. and Varnek, A.

Kernel Target Alignment Parameter: A New Modelability Measure for Regression Tasks

J Chem Inf Model (2016)

56, 6-11

10.1021/acs.jcim.5b00539

Marcou, G. and Horvath, D. and Varnek, A.

Neighboring Structure Visualization on a Grid-based Layout

Mol Inform (2017)

36,

10.1002/minf.201700047

Marechal, X. and Genin, E. and Qin, L. and Sperandio, O. and Montes, M. and Basse, N. and Richy, N. and Miteva, M. A. and Reboud-Ravaux, M. and Vidal, J. and Villoutreix, B. O.

1,2,4-Oxadiazoles identified by virtual screening and their non-covalent inhibition of the human 20S proteasome

Curr Med Chem (2013)

20, 2351-62

Margathe, J. F. and Iturrioz, X. and Alvear-Perez, R. and Marsol, C. and Riche, S. and Chabane, H. and Tounsi, N. and Kuhry, M. and Heissler, D. and Hibert, M. and Llorens-Cortes, C. and Bonnet, D.

Structure-activity relationship studies toward the discovery of selective apelin receptor agonists

J Med Chem (2014)

57, 2908-19

10.1021/jm401789v

Margathe, J. F. and Iturrioz, X. and Regenass, P. and Karpenko, I. A. and Humbert, N. and de Rocquigny, H. and Hibert, M. and Llorens-Cortes, C. and Bonnet, D.

Convenient Access to Fluorescent Probes by Chemoselective Acylation of Hydrazinopeptides: Application to the Synthesis of the First Far-Red Ligand for Apelin Receptor Imaging

Chemistry (2016)

22, 1399-405

10.1002/chem.201503630

Marhadour, S. and Marchand, P. and Pagniez, F. and Bazin, M. A. and Picot, C. and Lozach, O. and Ruchaud, S. and Antoine, M. and Meijer, L. and Rachidi, N. and Le Pape, P.

Synthesis and biological evaluation of 2,3-diarylimidazo[1,2-a]pyridines as antileishmanial agents

Eur J Med Chem (2012)

58, 543-56

10.1016/j.ejmech.2012.10.048

Marion, E. and Song, O. R. and Christophe, T. and Babonneau, J. and Fenistein, D. and Eyer, J. and Letournel, F. and Henrion, D. and Clere, N. and Paille, V. and Guerineau, N. C. and Saint Andre, J. P. and Gersbach, P. and Altmann, K. H. and Stinear, T. P. and Comoglio, Y. and Sandoz, G. and Preisser, L. and Delneste, Y. and Yeramian, E. and Marsollier, L. and Brodin, P.

Mycobacterial toxin induces analgesia in buruli ulcer by targeting the angiotensin pathways

Cell (2014)

157, 1565-76

10.1016/j.cell.2014.04.040

Marsolier, J. and Perichon, M. and DeBarry, J. D. and Villoutreix, B. O. and Chluba, J. and Lopez, T. and Garrido, C. and Zhou, X. Z. and Lu, K. P. and Fritsch, L. and Ait-Si-Ali, S. and Mhadhbi, M. and Medjkane, S. and Weitzman, J. B.

Theileria parasites secrete a prolyl isomerase to maintain host leukocyte transformation

Nature (2015)

520, 378-82

10.1038/nature14044

Martel, C. and Allouche, M. and Esposti, D. D. and Fanelli, E. and Boursier, C. and Henry, C. and Chopineau, J. and Calamita, G. and Kroemer, G. and Lemoine, A. and Brenner, C.

Glycogen synthase kinase 3-mediated voltage-dependent anion channel phosphorylation controls outer mitochondrial membrane permeability during lipid accumulation

Hepatology (2013)

57, 93-102

10.1002/hep.25967

Martel, C. and Esposti, D. D. and Bouchet, A. and Brenner, C. and Lemoine, A.

Non-alcoholic steatohepatitis: new insights from OMICS studies

Curr Pharm Biotechnol (2012)

13, 726-35

Martel, C. and Huynh le, H. and Garnier, A. and Ventura-Clapier, R. and Brenner, C.

Inhibition of the Mitochondrial Permeability Transition for Cytoprotection: Direct versus Indirect Mechanisms

Biochem Res Int (2012)

2012, 213403

10.1155/2012/213403

Martel, C. and Wang, Z. and Brenner, C.

VDAC phosphorylation, a lipid sensor influencing the cell fate

Mitochondrion (2014)

19 Pt A, 69-77

10.1016/j.mito.2014.07.009

Marti, G. and Eparvier, V. and Morleo, B. and Le Ven, J. and Apel, C. and Bodo, B. and Amand, S. and Dumontet, V. and Lozach, O. and Meijer, L. and Gueritte, F. and Litaudon, M.

Natural aristolactams and aporphine alkaloids as inhibitors of CDK1/cyclin B and DYRK1A

Molecules (2013)

18, 3018-27

10.3390/molecules18033018

Martin, B. and Canard, B. and Decroly, E.

Filovirus proteins for antiviral drug discovery: Structure/function bases of the replication cycle

Antiviral Res (2017)

141, 48-61

10.1016/j.antiviral.2017.02.004

Martin, B. and Hoenen, T. and Canard, B. and Decroly, E.

Filovirus proteins for antiviral drug discovery: A structure/function analysis of surface glycoproteins and virus entry

Antiviral Res (2016)

135, 1-14

10.1016/j.antiviral.2016.09.001

Martin-Jezequel, V. and Calu, G. and Candela, L. and Amzil, Z. and Jauffrais, T. and Sechet, V. and Weigel, P.

Effects of Organic and Inorganic Nitrogen on the Growth and Production of Domoic Acid by Pseudo-nitzschia multiseries and P. australis (Bacillariophyceae) in Culture

Mar Drugs (2015)

13, 7067-86

10.3390/md13127055

Martinez, A. and Soleilhac, E. and Barette, C. and Prudent, R. and Gozzi, G. J. and Vassal-Stermann, E. and Pillet, C. and Di Pietro, A. and Fauvarque, M. O. and Lafanechere, L.

Novel synthetic pharmacophores inducing a stabilization of cellular microtubules

Curr Cancer Drug Targets (2015)

15, 2-13

Martinez, J. and Fleury, F. and Varaldi, J.

Heritable variation in an extended phenotype: the case of a parasitoid manipulated by a virus

J Evol Biol (2012)

25, 54-65

10.1111/j.1420-9101.2011.02405.x

Martinez, J. and Fleury, F. and Varaldi, J.

Competitive outcome of multiple infections in a behavior-manipulating virus/wasp interaction

Ecol Evol (2015)

5, 5934-45

10.1002/ece3.1749

Martinez, J. and Lepetit, D. and Ravallec, M. and Fleury, F. and Varaldi, J.

Additional heritable virus in the parasitic wasp Leptopilina boulardi: prevalence, transmission and phenotypic effects

J Gen Virol (2016)

97, 523-35

10.1099/jgv.0.000360

Martinez, S. F. and Renodon-Corniere, A. and Nomme, J. and Eveillard, D. and Fleury, F. and Takahashi, M. and Weigel, P.

Targeting human Rad51 by specific DNA aptamers induces inhibition of homologous recombination

Biochimie (2010)

92, 1832-8

10.1016/j.biochi.2010.08.006

Martinez, T. and Texier, H. and Nahoum, V. and Lafitte, C. and Cioci, G. and Heux, L. and Dumas, B. and O'Donohue, M. and Gaulin, E. and Dumon, C.

Probing the Functions of Carbohydrate Binding Modules in the CBEL Protein from the Oomycete Phytophthora parasitica

PLoS One (2015)

10, e0137481

10.1371/journal.pone.0137481

Martinez-Sanz, J. and Bonnet, P. and Lozano, S. and Arrault, A. and Morin-Allory, L. and Vayer, P.

New QSAR Models for Human Cytochromes P450, 1A2, 2D6 and 3A4 Implicated in the Metabolism of Drugs. Relevance of Dataset on Model Development

Mol Inform (2013)

32, 573-7

10.1002/minf.201300031

Martins, I. and Raza, S. Q. and Voisin, L. and Dakhli, H. and Allouch, A. and Law, F. and Sabino, D. and De Jong, D. and Thoreau, M. and Mintet, E. and Dugue, D. and Piacentini, M. and Gougeon, M. L. and Jaulin, F. and Bertrand, P. and Brenner, C. and Ojcius, D. M. and Kroemer, G. and Modjtahedi, N. and Deutsch, E. and Perfettini, J. L.

Anticancer chemotherapy and radiotherapy trigger both non-cell-autonomous and cell-autonomous death

Cell Death Dis (2018)

9, 716

10.1038/s41419-018-0747-y

Martins, I. and Raza, S. Q. and Voisin, L. and Dakhli, H. and Law, F. and De Jong, D. and Allouch, A. and Thoreau, M. and Brenner, C. and Deutsch, E. and Perfettini, J. L.

Entosis: The emerging face of non-cell-autonomous type IV programmed death

Biomed J (2017)

40, 133-140

10.1016/j.bj.2017.05.001

Martiny, V. Y. and Carbonell, P. and Chevillard, F. and Moroy, G. and Nicot, A. B. and Vayer, P. and Villoutreix, B. O. and Miteva, M. A.

Integrated structure- and ligand-based in silico approach to predict inhibition of cytochrome P450 2D6

Bioinformatics (2015)

31, 3930-7

10.1093/bioinformatics/btv486

Martiny, V. Y. and Carbonell, P. and Lagorce, D. and Villoutreix, B. O. and Moroy, G. and Miteva, M. A.

In silico mechanistic profiling to probe small molecule binding to sulfotransferases

PLoS One (2013)

8, e73587

10.1371/journal.pone.0073587

Marton, Z. and Guillon, R. and Krimm, I. and Preeti and Rahimova, R. and Egron, D. and Jordheim, L. P. and Aghajari, N. and Dumontet, C. and Perigaud, C. and Lionne, C. and Peyrottes, S. and Chaloin, L.

Identification of Noncompetitive Inhibitors of Cytosolic 5'-Nucleotidase II Using a Fragment-Based Approach

J Med Chem (2015)

58, 9680-96

10.1021/acs.jmedchem.5b01616

Meirsman, A. C. and Le Merrer, J. and Pellissier, L. P. and Diaz, J. and Clesse, D. and Kieffer, B. L. and Becker, J. A.

Mice Lacking GPR88 Show Motor Deficit, Improved Spatial Learning, and Low Anxiety Reversed by Delta Opioid Antagonist

Biol Psychiatry (2016)

79, 917-27

10.1016/j.biopsych.2015.05.020

Menchon, G. and Bombarde, O. and Trivedi, M. and Negrel, A. and Inard, C. and Giudetti, B. and Baltas, M. and Milon, A. and Modesti, M. and Czaplicki, G. and Calsou, P.

Structure-Based Virtual Ligand Screening on the XRCC4/DNA Ligase IV Interface

Sci Rep (2016)

6, 22878

10.1038/srep22878

Menchon, G. and Maveyraud, L. and Czaplicki, G.

Molecular Dynamics as a Tool for Virtual Ligand Screening

Methods Mol Biol (2018)

1762, 145-178

10.1007/978-1-4939-7756-7_9

Menendez, C. and Chollet, A. and Rodriguez, F. and Inard, C. and Pasca, M. R. and Lherbet, C. and Baltas, M.

Chemical synthesis and biological evaluation of triazole derivatives as inhibitors of InhA and antituberculosis agents

Eur J Med Chem (2012)

52, 275-83

10.1016/j.ejmech.2012.03.029

Menendez, C. and Rodriguez, F. and Ribeiro, A. L. and Zara, F. and Frongia, C. and Lobjois, V. and Saffon, N. and Pasca, M. R. and Lherbet, C. and Baltas, M.

Synthesis and evaluation of alpha-ketotriazoles and alpha,beta-diketotriazoles as inhibitors of Mycobacterium tuberculosis

Eur J Med Chem (2013)

69, 167-73

10.1016/j.ejmech.2013.06.042

Menn, B. and Bach, S. and Blevins, T. L. and Campbell, M. and Meijer, L. and Timsit, S.

Delayed treatment with systemic (S)-roscovitine provides neuroprotection and inhibits in vivo CDK5 activity increase in animal stroke models

PLoS One (2010)

5, e12117

10.1371/journal.pone.0012117

Merour, J. Y. and Buron, F. and Ple, K. and Bonnet, P. and Routier, S.

The azaindole framework in the design of kinase inhibitors

Molecules (2014)

19, 19935-79

10.3390/molecules191219935

Mesbah, K. and Thai, R. and Bregant, S. and Malloggi, F.

DMF-MALDI: droplet based microfluidic combined to MALDI-TOF for focused peptide detection

Sci Rep (2017)

7, 6756

10.1038/s41598-017-06660-8

Meslamani, J. and Bhajun, R. and Martz, F. and Rognan, D.

Computational profiling of bioactive compounds using a target-dependent composite workflow

J Chem Inf Model (2013)

53, 2322-33

10.1021/ci400303n

Meslamani, J. and Li, J. and Sutter, J. and Stevens, A. and Bertrand, H. O. and Rognan, D.

Protein-ligand-based pharmacophores: generation and utility assessment in computational ligand profiling

J Chem Inf Model (2012)

52, 943-55

10.1021/ci300083r

Meslamani, J. and Rognan, D.

Enhancing the accuracy of chemogenomic models with a three-dimensional binding site kernel

J Chem Inf Model (2011)

51, 1593-603

10.1021/ci200166t

Meunier, I. and Bocquet, B. and Labesse, G. and Zeitz, C. and Defoort-Dhellemmes, S. and Lacroux, A. and Mauget-Faysse, M. and Drumare, I. and Gamez, A. S. and Mathieu, C. and Marquette, V. and Sagot, L. and Dhaenens, C. M. and Arndt, C. and Carroll, P. and Remy-Jardin, M. and Cohen, S. Y. and Sahel, J. A. and Puech, B. and Audo, I. and Mrejen, S. and Hamel, C. P.

A new autosomal dominant eye and lung syndrome linked to mutations in TIMP3 gene

Sci Rep (2016)

6, 32544

10.1038/srep32544

Meunier, I. and Lenaers, G. and Bocquet, B. and Baudoin, C. and Piro-Megy, C. and Cubizolle, A. and Quiles, M. and Jean-Charles, A. and Cohen, S. Y. and Merle, H. and Gaudric, A. and Labesse, G. and Manes, G. and Pequignot, M. and Cazevieille, C. and Dhaenens, C. M. and Fichard, A. and Ronkina, N. and Arthur, S. J. and Gaestel, M. and Hamel, C. P.

A dominant mutation in MAPKAPK3, an actor of p38 signaling pathway, causes a new retinal dystrophy involving Bruch's membrane and retinal pigment epithelium

Hum Mol Genet (2016)

25, 916-26

10.1093/hmg/ddv624

Michel, G. and Matthes, H. W. and Hachet-Haas, M. and El Baghdadi, K. and de Mey, J. and Pepperkok, R. and Simpson, J. C. and Galzi, J. L. and Lecat, S.

Plasma membrane translocation of REDD1 governed by GPCRs contributes to mTORC1 activation

J Cell Sci (2014)

127, 773-87

10.1242/jcs.136432

Michels, J. and Obrist, F. and Vitale, I. and Lissa, D. and Garcia, P. and Behnam-Motlagh, P. and Kohno, K. and Wu, G. S. and Brenner, C. and Castedo, M. and Kroemer, G.

MCL-1 dependency of cisplatin-resistant cancer cells

Biochem Pharmacol (2014)

92, 55-61

10.1016/j.bcp.2014.07.029

Michels, J. and Vitale, I. and Galluzzi, L. and Adam, J. and Olaussen, K. A. and Kepp, O. and Senovilla, L. and Talhaoui, I. and Guegan, J. and Enot, D. P. and Talbot, M. and Robin, A. and Girard, P. and Orear, C. and Lissa, D. and Sukkurwala, A. Q. and Garcia, P. and Behnam-Motlagh, P. and Kohno, K. and Wu, G. S. and Brenner, C. and Dessen, P. and Saparbaev, M. and Soria, J. C. and Castedo, M. and Kroemer, G.

Cisplatin resistance associated with PARP hyperactivation

Cancer Res (2013)

73, 2271-80

10.1158/0008-5472.CAN-12-3000

Paesen, G. C. and Collet, A. and Sallamand, C. and Debart, F. and Vasseur, J. J. and Canard, B. and Decroly, E. and Grimes, J. M.

X-ray structure and activities of an essential Mononegavirales L-protein domain

Nat Commun (2015)

6, 8749

10.1038/ncomms9749

Pallandre, J. R. and Borg, C. and Rognan, D. and Boibessot, T. and Luzet, V. and Yesylevskyy, S. and Ramseyer, C. and Pudlo, M.

Novel aminotetrazole derivatives as selective STAT3 non-peptide inhibitors

Eur J Med Chem (2015)

103, 163-74

10.1016/j.ejmech.2015.08.054

Pandey, R. R. and Homolka, D. and Chen, K. M. and Sachidanandam, R. and Fauvarque, M. O. and Pillai, R. S.

Recruitment of Armitage and Yb to a transcript triggers its phased processing into primary piRNAs in Drosophila ovaries

PLoS Genet (2017)

13, e1006956

10.1371/journal.pgen.1006956

Panozzo, C. and Laleve, A. and Tribouillard-Tanvier, D. and Ostojic, J. and Sellem, C. H. and Friocourt, G. and Bourand-Plantefol, A. and Burg, A. and Delahodde, A. and Blondel, M. and Dujardin, G.

Chemicals or mutations that target mitochondrial translation can rescue the respiratory deficiency of yeast bcs1 mutants

Biochim Biophys Acta (2017)

1864, 2297-2307

10.1016/j.bbamcr.2017.09.003

Paoletti, J. and Assairi, L. and Gelin, M. and Huteau, V. and Nahori, M. A. and Dussurget, O. and Labesse, G. and Pochet, S.

8-Thioalkyl-adenosine derivatives inhibit Listeria monocytogenes NAD kinase through a novel binding mode

Eur J Med Chem (2016)

124, 1041-1056

10.1016/j.ejmech.2016.10.033

Paoletti, P. and Pin, J. P.

Editorial overview: neurosciences: targeting glutamatergic signaling in CNS diseases: new hopes?

Curr Opin Pharmacol (2015)

20, iv-vi

10.1016/j.coph.2015.01.001

Papageorgiou, N. and Lichiere, J. and Baklouti, A. and Ferron, F. and Sevajol, M. and Canard, B. and Coutard, B.

Structural characterization of the N-terminal part of the MERS-CoV nucleocapsid by X-ray diffraction and small-angle X-ray scattering

Acta Crystallogr D Struct Biol (2016)

72, 192-202

10.1107/S2059798315024328

Pasquier, A. and Alais, S. and Roux, L. and Thoulouze, M. I. and Alvarez, K. and Journo, C. and Dutartre, H. and Mahieux, R.

How to Control HTLV-1-Associated Diseases: Preventing de Novo Cellular Infection Using Antiviral Therapy

Front Microbiol (2018)

9, 278

10.3389/fmicb.2018.00278

Patot, S. and Allemand, R. and Fleury, F. and Varaldi, J.

An inherited virus influences the coexistence of parasitoid species through behaviour manipulation

Ecol Lett (2012)

15, 603-10

10.1111/j.1461-0248.2012.01774.x

Patot, S. and Martinez, J. and Allemand, R. and Gandon, S. and Varaldi, J. and Fleury, F.

Prevalence of a virus inducing behavioural manipulation near species range border

Mol Ecol (2010)

19, 2995-3007

10.1111/j.1365-294X.2010.04686.x

Pauwels, E. and Surdez, D. and Stoll, G. and Lescure, A. and Del Nery, E. and Delattre, O. and Stoven, V.

A probabilistic model for cell population phenotyping using HCS data

PLoS One (2012)

7, e42715

10.1371/journal.pone.0042715

Payet, L. A. and Kadri, L. and Giraud, S. and Norez, C. and Berjeaud, J. M. and Jayle, C. and Mirval, S. and Becq, F. and Vandebrouck, C. and Ferreira, T.

Cystic fibrosis bronchial epithelial cells are lipointoxicated by membrane palmitate accumulation

PLoS One (2014)

9, e89044

10.1371/journal.pone.0089044

Payet, L. A. and Pineau, L. and Snyder, E. C. and Colas, J. and Moussa, A. and Vannier, B. and Bigay, J. and Clarhaut, J. and Becq, F. and Berjeaud, J. M. and Vandebrouck, C. and Ferreira, T.

Saturated fatty acids alter the late secretory pathway by modulating membrane properties

Traffic (2013)

14, 1228-41

10.1111/tra.12117

Pedroso, D. and Nunes, A. R. and Diogo, L. N. and Oudot, C. and Monteiro, E. C. and Brenner, C. and Vieira, H. L. A.

Hippocampal neurogenesis response: What can we expect from two different models of hypertension?

Brain Res (2016)

1646, 199-206

10.1016/j.brainres.2016.05.044

Pellissier, L. P. and Gandia, J. and Laboute, T. and Becker, J. A. J. and Le Merrer, J.

mu opioid receptor, social behaviour and autism spectrum disorder: reward matters

Br J Pharmacol (2018)

175, 2750-2769

10.1111/bph.13808

Michels, J. and Vitale, I. and Senovilla, L. and Enot, D. P. and Garcia, P. and Lissa, D. and Olaussen, K. A. and Brenner, C. and Soria, J. C. and Castedo, M. and Kroemer, G.

Synergistic interaction between cisplatin and PARP inhibitors in non-small cell lung cancer

Cell Cycle (2013)

12, 877-83

10.4161/cc.24034

Mignani, S. and El Brahmi, N. and Cresteil, T. and Majoral, J. P.

First-in-Class Combination Therapy of a Copper(II) Metallo-Phosphorus Dendrimer with Cytotoxic Agents

Oncology (2018)

94, 324-328

10.1159/000486680

Mignani, S. and El Brahmi, N. and El Kazzouli, S. and Eloy, L. and Courilleau, D. and Caron, J. and Bousmina, M. M. and Caminade, A. M. and Cresteil, T. and Majoral, J. P.

A novel class of ethacrynic acid derivatives as promising drug-like potent generation of anticancer agents with established mechanism of action

Eur J Med Chem (2016)

122, 656-673

10.1016/j.ejmech.2016.05.063

Mignani, S. and El Brahmi, N. and Eloy, L. and Poupon, J. and Nicolas, V. and Steinmetz, A. and El Kazzouli, S. and Bousmina, M. M. and Blanchard-Desce, M. and Caminade, A. M. and Majoral, J. P. and Cresteil, T.

Anticancer copper(II) phosphorus dendrimers are potent proapoptotic Bax activators

Eur J Med Chem (2017)

132, 142-156

10.1016/j.ejmech.2017.03.035

Mignani, S. M. and El Brahmi, N. and El Kazzouli, S. and Laurent, R. and Ladeira, S. and Caminade, A. M. and Pedziwiatr-Werbicka, E. and Szewczyk, E. M. and Bryszewska, M. and Bousmina, M. M. and Cresteil, T. and Majoral, J. P.

Original Multivalent Gold(III) and Dual Gold(III)-Copper(II) Conjugated Phosphorus Dendrimers as Potent Antitumoral and Antimicrobial Agents

Mol Pharm (2017)

14, 4087-4097

10.1021/acs.molpharmaceut.7b00771

Milhas, S. and Raux, B. and Betzi, S. and Derviaux, C. and Roche, P. and Restouin, A. and Basse, M. J. and Rebuffet, E. and Lugari, A. and Badol, M. and Kashyap, R. and Lissitzky, J. C. and Eydoux, C. and Hamon, V. and Gourdel, M. E. and Combes, S. and Zimmermann, P. and Aurrand-Lions, M. and Roux, T. and Rogers, C. and Muller, S. and Knapp, S. and Trinquet, E. and Collette, Y. and Guillemot, J. C. and Morelli, X.

Protein-Protein Interaction Inhibition (2P2I)-Oriented Chemical Library Accelerates Hit Discovery

ACS Chem Biol (2016)

11, 2140-8

10.1021/acschembio.6b00286

Milhomme, O. and Dhenin, S. G. and Djedaini-Pilard, F. and Moreau, V. and Grandjean, C.

Synthetic studies toward the anthrax tetrasaccharide: alternative synthesis of this antigen

Carbohydr Res (2012)

356, 115-31

10.1016/j.carres.2012.01.007

Milhomme, O. and John, C. and Djedaini-Pilard, F. and Grandjean, C.

Access to antigens related to anthrose using pivotal cyclic sulfite/sulfate intermediates

J Org Chem (2011)

76, 5985-98

10.1021/jo200340q

Milhomme, O. and Kohler, S. M. and Ropartz, D. and Lesur, D. and Pilard, S. and Djedaini-Pilard, F. and Beyer, W. and Grandjean, C.

Synthesis and immunochemical evaluation of a non-methylated disaccharide analogue of the anthrax tetrasaccharide

Org Biomol Chem (2012)

10, 8524-32

10.1039/c2ob26131f

Miteva, M. A. and Guyon, F. and Tuffery, P.

Frog2: Efficient 3D conformation ensemble generator for small compounds

Nucleic Acids Res (2010)

38, W622-7

10.1093/nar/gkq325

Miteva, M. A. and Villoutreix, B. O.

Computational Biology and Chemistry in MTi: Emphasis on the Prediction of Some ADMET Properties

Mol Inform (2017)

36,

10.1002/minf.201700008

Mohlin, F. C. and Nilsson, S. C. and Levart, T. K. and Golubovic, E. and Rusai, K. and Muller-Sacherer, T. and Arbeiter, K. and Pallinger, E. and Szarvas, N. and Csuka, D. and Szilagyi, A. and Villoutreix, B. O. and Prohaszka, Z. and Blom, A. M.

Functional characterization of two novel non-synonymous alterations in CD46 and a Q950H change in factor H found in atypical hemolytic uremic syndrome patients

Mol Immunol (2015)

65, 367-76

10.1016/j.molimm.2015.02.013

Moine, E. and Dimier-Poisson, I. and Enguehard-Gueiffier, C. and Loge, C. and Penichon, M. and Moire, N. and Delehouze, C. and Foll-Josselin, B. and Ruchaud, S. and Bach, S. and Gueiffier, A. and Debierre-Grockiego, F. and Denevault-Sabourin, C.

Development of new highly potent imidazo[1,2-b]pyridazines targeting Toxoplasma gondii calcium-dependent protein kinase 1

Eur J Med Chem (2015)

105, 80-105

10.1016/j.ejmech.2015.10.004

Moiroux, J. and Delava, E. and Fleury, F. and van Baaren, J.

Local adaptation of a Drosophila parasitoid: habitat-specific differences in thermal reaction norms

J Evol Biol (2013)

26, 1108-16

10.1111/jeb.12122

Moller, T. C. and Hottin, J. and Clerte, C. and Zwier, J. M. and Durroux, T. and Rondard, P. and Prezeau, L. and Royer, C. A. and Pin, J. P. and Margeat, E. and Kniazeff, J.

Oligomerization of a G protein-coupled receptor in neurons controlled by its structural dynamics

Sci Rep (2018)

8, 10414

10.1038/s41598-018-28682-6

Moller, T. C. and Moreno-Delgado, D. and Pin, J. P. and Kniazeff, J.

Class C G protein-coupled receptors: reviving old couples with new partners

Biophys Rep (2017)

3, 57-63

10.1007/s41048-017-0036-9

Montaigne, D. and Marechal, X. and Modine, T. and Coisne, A. and Mouton, S. and Fayad, G. and Ninni, S. and Klein, C. and Ortmans, S. and Seunes, C. and Potelle, C. and Berthier, A. and Gheeraert, C. and Piveteau, C. and Deprez, R. and Eeckhoute, J. and Duez, H. and Lacroix, D. and Deprez, B. and Jegou, B. and Koussa, M. and Edme, J. L. and Lefebvre, P. and Staels, B.

Daytime variation of perioperative myocardial injury in cardiac surgery and its prevention by Rev-Erbalpha antagonism: a single-centre propensity-matched cohort study and a randomised study

Lancet (2018)

391, 59-69

10.1016/S0140-6736(17)32132-3

Montier, T. and Pichon, C. and Blondel, M. and Midoux, P.

Editorial: Current status and prospects on nucleic acid transfer

Biotechnol J (2014)

9, 1363-4

10.1002/biot.201300510

Morelli, X. and Bourgeas, R. and Roche, P.

Chemical and structural lessons from recent successes in protein-protein interaction inhibition (2P2I)

Curr Opin Chem Biol (2011)

15, 475-81

10.1016/j.cbpa.2011.05.024

Morelli, X. and Hupp, T.

Searching for the Holy Grail; protein-protein interaction analysis and modulation

EMBO Rep (2012)

13, 877-9

10.1038/embor.2012.137

Morelli, X. and Rieux, C. and Cyrys, J. and Forsberg, B. and Slama, R.

Corrigendum to "Air pollution, health and social deprivation: A fine-scale risk assessment" [Environ. Res. 147 (2016) 59-70]

Environ Res (2016)

150, 664

10.1016/j.envres.2016.06.005

Morelli, X. and Rieux, C. and Cyrys, J. and Forsberg, B. and Slama, R.

Air pollution, health and social deprivation: A fine-scale risk assessment

Environ Res (2016)

147, 59-70

10.1016/j.envres.2016.01.030

Moreno Delgado, D. and Moller, T. C. and Ster, J. and Giraldo, J. and Maurel, D. and Rovira, X. and Scholler, P. and Zwier, J. M. and Perroy, J. and Durroux, T. and Trinquet, E. and Prezeau, L. and Rondard, P. and Pin, J. P.

Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells

Elife (2017)

6,

10.7554/eLife.25233

Morille, M. and Montier, T. and Legras, P. and Carmoy, N. and Brodin, P. and Pitard, B. and Benoit, J. P. and Passirani, C.

Long-circulating DNA lipid nanocapsules as new vector for passive tumor targeting

Biomaterials (2010)

31, 321-9

10.1016/j.biomaterials.2009.09.044

Morin, B. and Rabah, N. and Boretto-Soler, J. and Tolou, H. and Alvarez, K. and Canard, B.

High yield synthesis, purification and characterisation of the RNase L activators 5'-triphosphate 2'-5'-oligoadenylates

Antiviral Res (2010)

87, 345-52

10.1016/j.antiviral.2010.06.003

Moroy, G. and Martiny, V. Y. and Vayer, P. and Villoutreix, B. O. and Miteva, M. A.

Toward in silico structure-based ADMET prediction in drug discovery

Drug Discov Today (2012)

17, 44-55

10.1016/j.drudis.2011.10.023

Moroy, G. and Sperandio, O. and Rielland, S. and Khemka, S. and Druart, K. and Goyal, D. and Perahia, D. and Miteva, M. A.

Sampling of conformational ensemble for virtual screening using molecular dynamics simulations and normal mode analysis

Future Med Chem (2015)

7, 2317-31

10.4155/fmc.15.150

Motuhi, S. E. and Mehiri, M. and Payri, C. E. and La Barre, S. and Bach, S.

Marine Natural Products from New Caledonia--A Review

Mar Drugs (2016)

14,

10.3390/md14030058

Moucadel, V. and Prudent, R. and Sautel, C. F. and Teillet, F. and Barette, C. and Lafanechere, L. and Receveur-Brechot, V. and Cochet, C.

Antitumoral activity of allosteric inhibitors of protein kinase CK2

Oncotarget (2011)

2, 997-1010

10.18632/oncotarget.361

Mouhsine, H. and Guillemain, H. and Moreau, G. and Fourati, N. and Zerrouki, C. and Baron, B. and Desallais, L. and Gizzi, P. and Ben Nasr, N. and Perrier, J. and Ratsimandresy, R. and Spadoni, J. L. and Do, H. and England, P. and Montes, M. and Zagury, J. F.

Identification of an in vivo orally active dual-binding protein-protein interaction inhibitor targeting TNFalpha through combined in silico/in vitro/in vivo screening

Sci Rep (2017)

7, 3424

10.1038/s41598-017-03427-z

Mousseau, G. and Raffy, Q. and Thomas, O. P. and Agez, M. and Thai, R. and Renault, J. P. and Pin, S. and Ochsenbein, F. and Cintrat, J. C. and Rousseau, B.

Footprinting of protein interactions by tritium labeling

Biochemistry (2010)

49, 4297-9

10.1021/bi100031a

Moutin, E. and Compan, V. and Raynaud, F. and Clerte, C. and Bouquier, N. and Labesse, G. and Ferguson, M. L. and Fagni, L. and Royer, C. A. and Perroy, J.

The stoichiometry of scaffold complexes in living neurons - DLC2 functions as a dimerization engine for GKAP

J Cell Sci (2014)

127, 3451-62

10.1242/jcs.145748

Mouton, L. and Gnankine, O. and Henri, H. and Terraz, G. and Ketoh, G. and Martin, T. and Fleury, F. and Vavre, F.

Detection of genetically isolated entities within the Mediterranean species of Bemisia tabaci: new insights into the systematics of this worldwide pest

Pest Manag Sci (2015)

71, 452-8

10.1002/ps.3834

Muller, C. and Marcou, G. and Horvath, D. and Aires-de-Sousa, J. and Varnek, A.

Models for identification of erroneous atom-to-atom mapping of reactions performed by automated algorithms

J Chem Inf Model (2012)

52, 3116-22

10.1021/ci300418q

Muller, C. and Pekthong, D. and Alexandre, E. and Marcou, G. and Horvath, D. and Richert, L. and Varnek, A.

Prediction of drug induced liver injury using molecular and biological descriptors

Comb Chem High Throughput Screen (2015)

18, 315-22

Muller-Bouvet, D. and Emery, N. and Tassali, N. and Panabiere, E. and Bach, S. and Crosnier, O. and Brousse, T. and Cenac-Morthe, C. and Michalowicz, A. and Pereira-Ramos, J. P.

Unravelling redox processes of Li7MnN4 upon electrochemical Li extraction-insertion using operando XAS

Phys Chem Chem Phys (2017)

19, 27204-27211

10.1039/c7cp05207c

Muller-Bouvet, D. and Pereira-Ramos, J. P. and Bach, S. and Willmann, P. and Michalowicz, A.

Effect of cobalt substitution on Li(3-2x)Co(x)N local structure: a XAS investigation

Inorg Chem (2014)

53, 6127-31

10.1021/ic500528f

Munier-Lehmann, H. and Lucas-Hourani, M. and Guillou, S. and Helynck, O. and Zanghi, G. and Noel, A. and Tangy, F. and Vidalain, P. O. and Janin, Y. L.

Original 2-(3-alkoxy-1H-pyrazol-1-yl)pyrimidine derivatives as inhibitors of human dihydroorotate dehydrogenase (DHODH)

J Med Chem (2015)

58, 860-77

10.1021/jm501446r

Munier-Lehmann, H. and Vidalain, P. O. and Tangy, F. and Janin, Y. L.

On dihydroorotate dehydrogenases and their inhibitors and uses

J Med Chem (2013)

56, 3148-67

10.1021/jm301848w

Munoz-Durango, K. and Maciuk, A. and Harfouche, A. and Torijano-Gutierrez, S. and Jullian, J. C. and Quintin, J. and Spelman, K. and Mouray, E. and Grellier, P. and Figadere, B.

Detection, characterization, and screening of heme-binding molecules by mass spectrometry for malaria drug discovery

Anal Chem (2012)

84, 3324-9

10.1021/ac300065t

Murie, C. and Barette, C. and Button, J. and Lafanechere, L. and Nadon, R.

Improving detection of rare biological events in high-throughput screens

J Biomol Screen (2015)

20, 230-41

10.1177/1087057114548853

Murie, C. and Barette, C. and Lafanechere, L. and Nadon, R.

Single assay-wide variance experimental (SAVE) design for high-throughput screening

Bioinformatics (2013)

29, 3067-72

10.1093/bioinformatics/btt538

Murie, C. and Barette, C. and Lafanechere, L. and Nadon, R.

Control-Plate Regression (CPR) Normalization for High-Throughput Screens with Many Active Features

J Biomol Screen (2014)

19, 661-71

10.1177/1087057113516003

Myrianthopoulos, V. and Lozach, O. and Zareifi, D. and Alexopoulos, L. and Meijer, L. and Gorgoulis, V. G. and Mikros, E.

Combined Virtual and Experimental Screening for CK1 Inhibitors Identifies a Modulator of p53 and Reveals Important Aspects of in Silico Screening Performance

Int J Mol Sci (2017)

18,

10.3390/ijms18102102

Namukobe, J. and Kiremire, B. T. and Byamukama, R. and Kasenene, J. M. and Akala, H. M. and Kamau, E. and Dumontet, V.

Antiplasmodial compounds from the stem bark of Neoboutonia macrocalyx pax

J Ethnopharmacol (2015)

162, 317-22

10.1016/j.jep.2014.12.018

Namukobe, J. and Kiremire, B. T. and Byamukama, R. and Kasenene, J. M. and Dumontet, V. and Gueritte, F. and Krief, S. and Florent, I. and Kabasa, J. D.

Cycloartane triterpenes from the leaves of Neoboutonia macrocalyx L

Phytochemistry (2014)

102, 189-96

10.1016/j.phytochem.2014.02.005

Naret, T. and Bignon, J. and Bernadat, G. and Benchekroun, M. and Levaique, H. and Lenoir, C. and Dubois, J. and Pruvost, A. and Saller, F. and Borgel, D. and Manoury, B. and Leblais, V. and Darrigrand, R. and Apcher, S. and Brion, J. D. and Schmitt, E. and Leroux, F. R. and Alami, M. and Hamze, A.

A fluorine scan of a tubulin polymerization inhibitor isocombretastatin A-4: Design, synthesis, molecular modelling, and biological evaluation

Eur J Med Chem (2018)

143, 473-490

10.1016/j.ejmech.2017.11.055

Nasrallah, C. and Rottier, K. and Marcellin, R. and Compan, V. and Font, J. and Llebaria, A. and Pin, J. P. and Baneres, J. L. and Lebon, G.

Direct coupling of detergent purified human mGlu5 receptor to the heterotrimeric G proteins Gq and Gs

Sci Rep (2018)

8, 4407

10.1038/s41598-018-22729-4

Navarri, M. and Jegou, C. and Bondon, A. and Pottier, S. and Bach, S. and Baratte, B. and Ruchaud, S. and Barbier, G. and Burgaud, G. and Fleury, Y.

Bioactive Metabolites from the Deep Subseafloor Fungus Oidiodendron griseum UBOCC-A-114129

Mar Drugs (2017)

15,

10.3390/md15040111

Neres, J. and Hartkoorn, R. C. and Chiarelli, L. R. and Gadupudi, R. and Pasca, M. R. and Mori, G. and Venturelli, A. and Savina, S. and Makarov, V. and Kolly, G. S. and Molteni, E. and Binda, C. and Dhar, N. and Ferrari, S. and Brodin, P. and Delorme, V. and Landry, V. and de Jesus Lopes Ribeiro, A. L. and Farina, D. and Saxena, P. and Pojer, F. and Carta, A. and Luciani, R. and Porta, A. and Zanoni, G. and De Rossi, E. and Costi, M. P. and Riccardi, G. and Cole, S. T.

2-Carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1

ACS Chem Biol (2015)

10, 705-14

10.1021/cb5007163

Neuberg, P. and Hamaidi, I. and Danilin, S. and Ripoll, M. and Lindner, V. and Nothisen, M. and Wagner, A. and Kichler, A. and Massfelder, T. and Remy, J. S.

Polydiacetylenic nanofibers as new siRNA vehicles for in vitro and in vivo delivery

Nanoscale (2018)

10, 1587-1590

10.1039/c7nr09202d

Ngo, C. T. and Dubois, G. and Sinou, V. and Parzy, D. and Le, H. Q. and Harbach, R. E. and Manguin, S.

Diversity of Anopheles mosquitoes in Binh Phuoc and Dak Nong Provinces of Vietnam and their relation to disease

Parasit Vectors (2014)

7, 316

10.1186/1756-3305-7-316

Nguyen, P. and Oumata, N. and Soubigou, F. and Evrard, J. and Desban, N. and Lemoine, P. and Bouaziz, S. and Blondel, M. and Voisset, C.

Evaluation of the antiprion activity of 6-aminophenanthridines and related heterocycles

Eur J Med Chem (2014)

82, 363-71

10.1016/j.ejmech.2014.05.083

Nguyen, P. C. and Delorme, V. and Benarouche, A. and Martin, B. P. and Paudel, R. and Gnawali, G. R. and Madani, A. and Puppo, R. and Landry, V. and Kremer, L. and Brodin, P. and Spilling, C. D. and Cavalier, J. F. and Canaan, S.

Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis

Sci Rep (2017)

7, 11751

10.1038/s41598-017-11843-4

Nguyen, P. H. and Hammoud, H. and Halliez, S. and Pang, Y. and Evrard, J. and Schmitt, M. and Oumata, N. and Bourguignon, J. J. and Sanyal, S. and Beringue, V. and Blondel, M. and Bihel, F. and Voisset, C.

Structure-activity relationship study around guanabenz identifies two derivatives retaining antiprion activity but having lost alpha2-adrenergic receptor agonistic activity

ACS Chem Neurosci (2014)

5, 1075-82

10.1021/cn5001588

Nicolas-Chanoine, M. H. and Mayer, N. and Guyot, K. and Dumont, E. and Pages, J. M.

Interplay Between Membrane Permeability and Enzymatic Barrier Leads to Antibiotic-Dependent Resistance in Klebsiella Pneumoniae

Front Microbiol (2018)

9, 1422

10.3389/fmicb.2018.01422

Nikiforov, P. O. and Blaszczyk, M. and Surade, S. and Boshoff, H. I. and Sajid, A. and Delorme, V. and Deboosere, N. and Brodin, P. and Baulard, A. R. and Barry, C. E., 3rd and Blundell, T. L. and Abell, C.

Fragment-Sized EthR Inhibitors Exhibit Exceptionally Strong Ethionamide Boosting Effect in Whole-Cell Mycobacterium tuberculosis Assays

ACS Chem Biol (2017)

12, 1390-1396

10.1021/acschembio.7b00091

Nkoli Mandoko, P. and Rouvier, F. and Matendo Kakina, L. and Moke Mbongi, D. and Latour, C. and Losimba Likwela, J. and Ngoyi Mumba, D. and Bi Shamamba, S. K. and Tamfum Muyembe, J. J. and Muepu Tshilolo, L. and Parzy, D. and Sinou, V.

Prevalence of Plasmodium falciparum parasites resistant to sulfadoxine/pyrimethamine in the Democratic Republic of the Congo: emergence of highly resistant pfdhfr/pfdhps alleles

J Antimicrob Chemother (2018)

,

10.1093/jac/dky258

Nkoli Mandoko, P. and Sinou, V. and Moke Mbongi, D. and Ngoyi Mumba, D. and Kahunu Mesia, G. and Losimba Likwela, J. and Bi Shamamba Karhemere, S. and Muepu Tshilolo, L. and Tamfum Muyembe, J. J. and Parzy, D.

Access to artemisinin-based combination therapies and other anti-malarial drugs in Kinshasa

Med Mal Infect (2018)

48, 269-277

10.1016/j.medmal.2018.02.003

Nocquet, P. A. and Hensienne, R. and Wencel-Delord, J. and Laigre, E. and Sidelarbi, K. and Becq, F. and Norez, C. and Hazelard, D. and Compain, P.

Pushing the limits of catalytic C-H amination in polyoxygenated cyclobutanes

Org Biomol Chem (2016)

14, 2780-96

10.1039/c5ob02602d

Noel, R. and Gupta, N. and Pons, V. and Goudet, A. and Garcia-Castillo, M. D. and Michau, A. and Martinez, J. and Buisson, D. A. and Johannes, L. and Gillet, D. and Barbier, J. and Cintrat, J. C.

N-methyldihydroquinazolinone derivatives of Retro-2 with enhanced efficacy against Shiga toxin

J Med Chem (2013)

56, 3404-13

10.1021/jm4002346

Noel, S. and Gasser, V. and Pesset, B. and Hoegy, F. and Rognan, D. and Schalk, I. J. and Mislin, G. L.

Synthesis and biological properties of conjugates between fluoroquinolones and a N3''-functionalized pyochelin

Org Biomol Chem (2011)

9, 8288-300

10.1039/c1ob06250f

Noel, S. and Hoegy, F. and Rivault, F. and Rognan, D. and Schalk, I. J. and Mislin, G. L.

Synthesis and biological properties of thiazole-analogues of pyochelin, a siderophore of Pseudomonas aeruginosa

Bioorg Med Chem Lett (2014)

24, 132-5

10.1016/j.bmcl.2013.11.054

Nonnenmacher, M. E. and Cintrat, J. C. and Gillet, D. and Weber, T.

Syntaxin 5-dependent retrograde transport to the trans-Golgi network is required for adeno-associated virus transduction

J Virol (2015)

89, 1673-87

10.1128/JVI.02520-14

Norez, C. and Jayle, C. and Becq, F. and Vandebrouck, C.

Bronchorelaxation of the human bronchi by CFTR activators

Pulm Pharmacol Ther (2014)

27, 38-43

10.1016/j.pupt.2013.06.008

Norez, C. and Vandebrouck, C. and Bertrand, J. and Noel, S. and Durieu, E. and Oumata, N. and Galons, H. and Antigny, F. and Chatelier, A. and Bois, P. and Meijer, L. and Becq, F.

Roscovitine is a proteostasis regulator that corrects the trafficking defect of F508del-CFTR by a CDK-independent mechanism

Br J Pharmacol (2014)

171, 4831-49

10.1111/bph.12859

Nothias-Scaglia, L. F. and Dumontet, V. and Neyts, J. and Roussi, F. and Costa, J. and Leyssen, P. and Litaudon, M. and Paolini, J.

LC-MS(2)-Based dereplication of Euphorbia extracts with anti-Chikungunya virus activity

Fitoterapia (2015)

105, 202-9

10.1016/j.fitote.2015.06.021

Nothias-Scaglia, L. F. and Gallard, J. F. and Dumontet, V. and Roussi, F. and Costa, J. and Iorga, B. I. and Paolini, J. and Litaudon, M.

Advanced Structural Determination of Diterpene Esters Using Molecular Modeling and NMR Spectroscopy

J Nat Prod (2015)

78, 2423-31

10.1021/acs.jnatprod.5b00511

Nothias-Scaglia, L. F. and Retailleau, P. and Paolini, J. and Pannecouque, C. and Neyts, J. and Dumontet, V. and Roussi, F. and Leyssen, P. and Costa, J. and Litaudon, M.

Jatrophane diterpenes as inhibitors of chikungunya virus replication: structure-activity relationship and discovery of a potent lead

J Nat Prod (2014)

77, 1505-12

10.1021/np500271u

Nougarede, A. and Popgeorgiev, N. and Kassem, L. and Omarjee, S. and Borel, S. and Mikaelian, I. and Lopez, J. and Gadet, R. and Marcillat, O. and Treilleux, I. and Villoutreix, B. O. and Rimokh, R. and Gillet, G.

Breast Cancer Targeting through Inhibition of the Endoplasmic Reticulum-Based Apoptosis Regulator Nrh/BCL2L10

Cancer Res (2018)

78, 1404-1417

10.1158/0008-5472.CAN-17-0846

Novoa, A. and Pellegrini-Moise, N. and Bourg, S. and Thoret, S. and Dubois, J. and Aubert, G. and Cresteil, T. and Chapleur, Y.

Design, synthesis and antiproliferative activities of biarylolefins based on polyhydroxylated and carbohydrate scaffolds

Eur J Med Chem (2011)

46, 3570-80

10.1016/j.ejmech.2011.05.021

Nury, C. and Bregant, S. and Czarny, B. and Berthon, F. and Cassar-Lajeunesse, E. and Dive, V.

Detection of endogenous matrix metalloprotease-12 active form with a novel broad spectrum activity-based probe

J Biol Chem (2013)

288, 5636-44

10.1074/jbc.M112.419499

Nury, C. and Czarny, B. and Cassar-Lajeunesse, E. and Georgiadis, D. and Bregant, S. and Dive, V.

A pan photoaffinity probe for detecting active forms of matrix metalloproteinases

Chembiochem (2013)

14, 107-14

10.1002/cbic.201200583

Ochsenbein, F. and Morelli, X. and Verma, C.

Editorial. Protein-Protein Interaction Analysis and Modulation

Prog Biophys Mol Biol (2015)

119, 1

10.1016/j.pbiomolbio.2015.08.019

Oliveira, P. F. M. and Guidetti, B. and Chamayou, A. and Andre-Barres, C. and Madacki, J. and Kordulakova, J. and Mori, G. and Orena, B. S. and Chiarelli, L. R. and Pasca, M. R. and Lherbet, C. and Carayon, C. and Massou, S. and Baron, M. and Baltas, M.

Mechanochemical Synthesis and Biological Evaluation of Novel Isoniazid Derivatives with Potent Antitubercular Activity

Molecules (2017)

22,

10.3390/molecules22091457

Olivon, F. and Nothias, L. F. and Dumontet, V. and Retailleau, P. and Berger, S. and Ferry, G. and Cohen, W. and Pfeiffer, B. and Boutin, J. A. and Scalbert, E. and Roussi, F. and Litaudon, M.

Natural Inhibitors of the RhoA-p115 Complex from the Bark of Meiogyne baillonii

J Nat Prod (2018)

81, 1610-1618

10.1021/acs.jnatprod.8b00209

Olofsson, L. and Felekyan, S. and Doumazane, E. and Scholler, P. and Fabre, L. and Zwier, J. M. and Rondard, P. and Seidel, C. A. and Pin, J. P. and Margeat, E.

Fine tuning of sub-millisecond conformational dynamics controls metabotropic glutamate receptors agonist efficacy

Nat Commun (2014)

5, 5206

10.1038/ncomms6206

Oprisiu, I. and Varlamova, E. and Muratov, E. and Artemenko, A. and Marcou, G. and Polishchuk, P. and Kuz'min, V. and Varnek, A.

QSPR Approach to Predict Nonadditive Properties of Mixtures. Application to Bubble Point Temperatures of Binary Mixtures of Liquids

Mol Inform (2012)

31, 491-502

10.1002/minf.201200006

Ouach, A. and Boulahjar, R. and Vala, C. and Bourg, S. and Bonnet, P. and Guguen-Guillouzo, C. and Ravache, M. and Le Guevel, R. and Lozach, O. and Lazar, S. and Troin, Y. and Meijer, L. and Ruchaud, S. and Akssira, M. and Guillaumet, G. and Routier, S.

Novel optimization of valmerins (tetrahydropyrido[1,2-a]isoindolones) as potent dual CDK5/GSK3 inhibitors

Eur J Med Chem (2016)

115, 311-25

10.1016/j.ejmech.2016.02.072

Ouairy, C. and Cresteil, T. and Delpech, B. and Crich, D.

Synthesis and evaluation of 3-deoxy and 3-deoxy-3-fluoro derivatives of gluco- and manno-configured tetrahydropyridoimidazole glycosidase inhibitors

Carbohydr Res (2013)

377, 35-43

10.1016/j.carres.2013.05.011

Oueslati, N. and Hounsou, C. and Belhocine, A. and Rodriguez, T. and Dupuis, E. and Zwier, J. M. and Trinquet, E. and Pin, J. P. and Durroux, T.

Time-resolved FRET strategy to screen GPCR ligand library

Methods Mol Biol (2015)

1272, 23-36

10.1007/978-1-4939-2336-6_2

Ouidir, M. and Giorgis-Allemand, L. and Lyon-Caen, S. and Morelli, X. and Cracowski, C. and Pontet, S. and Pin, I. and Lepeule, J. and Siroux, V. and Slama, R.

Estimation of exposure to atmospheric pollutants during pregnancy integrating space-time activity and indoor air levels: Does it make a difference?

Environ Int (2015)

84, 161-73

10.1016/j.envint.2015.07.021

Oussaief, L. and Ramirez, V. and Hippocrate, A. and Arbach, H. and Cochet, C. and Proust, A. and Raphael, M. and Khelifa, R. and Joab, I.

NF-kappaB-mediated modulation of inducible nitric oxide synthase activity controls induction of the Epstein-Barr virus productive cycle by transforming growth factor beta 1

J Virol (2011)

85, 6502-12

10.1128/JVI.02560-10

Ouvry, G. and Berton, Y. and Bhurruth-Alcor, Y. and Bonnary, L. and Bouix-Peter, C. and Bouquet, K. and Bourotte, M. and Chambon, S. and Comino, C. and Deprez, B. and Duvert, D. and Duvert, G. and Hacini-Rachinel, F. and Harris, C. S. and Luzy, A. P. and Mathieu, A. and Millois, C. and Pascau, J. and Pinto, A. and Polge, G. and Reitz, A. and Reverse, K. and Rosignoli, C. and Taquet, N. and Hennequin, L. F.

Identification of novel TACE inhibitors compatible with topical application

Bioorg Med Chem Lett (2017)

27, 1848-1853

10.1016/j.bmcl.2017.02.035

Ovadia, R. and Lebrun, A. and Barvik, I. and Vasseur, J. J. and Baraguey, C. and Alvarez, K.

Synthesis and structural characterization of monomeric and dimeric peptide nucleic acids prepared by using microwave-promoted multicomponent reactions

Org Biomol Chem (2015)

13, 11052-71

10.1039/c5ob01604e

Oyallon, B. and Brachet-Botineau, M. and Loge, C. and Bonnet, P. and Souab, M. and Robert, T. and Ruchaud, S. and Bach, S. and Berthelot, P. and Gouilleux, F. and Viaud-Massuard, M. C. and Denevault-Sabourin, C.

Structure-based design of novel quinoxaline-2-carboxylic acids and analogues as Pim-1 inhibitors

Eur J Med Chem (2018)

154, 101-109

10.1016/j.ejmech.2018.04.056

Pacou, M. and Gauthier, A. and Taieb, V. and Bec, M. and Belhadi, D. and Guillemot, J.

Proposed Checklist for Non-Statisticians To Assess the Quality of A Network Meta-Analysis in the Context of A Nice Submission

Value Health (2014)

17, A579-80

10.1016/j.jval.2014.08.1960

Padilla, A. and Amiable, C. and Pochet, S. and Kaminski, P. A. and Labesse, G.

Structure of the oncoprotein Rcl bound to three nucleotide analogues

Acta Crystallogr D Biol Crystallogr (2013)

69, 247-55

10.1107/S0907444912045039

Rognan, D. and Bonnet, P.

[Chemical databases and virtual screening]

Med Sci (Paris) (2014)

30, 1152-60

10.1051/medsci/20143012019

Rognan, D. and Varnek, A.

A Summer School for Structuring the Chemoinformatics Community

Mol Inform (2014)

33, 390

10.1002/minf.201480631

Roland, S. and Jolivalt, C. and Cresteil, T. and Eloy, L. and Bouhours, P. and Hequet, A. and Mansuy, V. and Vanucci, C. and Paris, J. M.

Investigation of a series of silver-N-heterocyclic carbenes as antibacterial agents: activity, synergistic effects, and cytotoxicity

Chemistry (2011)

17, 1442-6

10.1002/chem.201002812

Romain, B. and Hachet-Haas, M. and Rohr, S. and Brigand, C. and Galzi, J. L. and Gaub, M. P. and Pencreach, E. and Guenot, D.

Hypoxia differentially regulated CXCR4 and CXCR7 signaling in colon cancer

Mol Cancer (2014)

13, 58

10.1186/1476-4598-13-58

Rondard, P. and Pin, J. P.

Dynamics and modulation of metabotropic glutamate receptors

Curr Opin Pharmacol (2015)

20, 95-101

10.1016/j.coph.2014.12.001

Rose, F. and Basu, S. and Rexhepaj, E. and Chauchereau, A. and Del Nery, E. and Genovesio, A.

Compound Functional Prediction Using Multiple Unrelated Morphological Profiling Assays

SLAS Technol (2018)

23, 243-251

10.1177/2472630317740831

Rossi, B. M. and Palmero, E. I. and Lopez-Kostner, F. and Sarroca, C. and Vaccaro, C. A. and Spirandelli, F. and Ashton-Prolla, P. and Rodriguez, Y. and de Campos Reis Galvao, H. and Reis, R. M. and Escremim de Paula, A. and Capochin Romagnolo, L. G. and Alvarez, K. and Della Valle, A. and Neffa, F. and Kalfayan, P. G. and Spirandelli, E. and Chialina, S. and Gutierrez Angulo, M. and Castro-Mujica, M. D. C. and Sanchez de Monte, J. and Quispe, R. and da Silva, S. D. and Rossi, N. T. and Barletta-Carrillo, C. and Revollo, S. and Taborga, X. and Morillas, L. L. and Tubeuf, H. and Monteiro-Santos, E. M. and Pinero, T. A. and Dominguez-Barrera, C. and Wernhoff, P. and Martins, A. and Hovig, E. and Moller, P. and Dominguez-Valentin, M.

A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America

BMC Cancer (2017)

17, 623

10.1186/s12885-017-3599-4

Rouch, A. and Vanucci-Bacque, C. and Bedos-Belval, F. and Baltas, M.

Small molecules inhibitors of plasminogen activator inhibitor-1 - an overview

Eur J Med Chem (2015)

92, 619-36

10.1016/j.ejmech.2015.01.010

Roumeas, L. and Humbert, J. P. and Schneider, S. and Doebelin, C. and Bertin, I. and Schmitt, M. and Bourguignon, J. J. and Simonin, F. and Bihel, F.

Effects of systematic N-terminus deletions and benzoylations of endogenous RF-amide peptides on NPFF1R, NPFF2R, GPR10, GPR54 and GPR103

Peptides (2015)

71, 156-61

10.1016/j.peptides.2015.07.016

Rousseau, A. and McEwen, A. G. and Poussin-Courmontagne, P. and Rognan, D. and Nomine, Y. and Rio, M. C. and Tomasetto, C. and Alpy, F.

TRAF4 is a novel phosphoinositide-binding protein modulating tight junctions and favoring cell migration

PLoS Biol (2013)

11, e1001726

10.1371/journal.pbio.1001726

Roussel, J. and Thireau, J. and Brenner, C. and Saint, N. and Scheuermann, V. and Lacampagne, A. and Le Guennec, J. Y. and Fauconnier, J.

Palmitoyl-carnitine increases RyR2 oxidation and sarcoplasmic reticulum Ca2+ leak in cardiomyocytes: Role of adenine nucleotide translocase

Biochim Biophys Acta (2015)

1852, 749-58

10.1016/j.bbadis.2015.01.011

Rousserie, G. and Sukhanova, A. and Even-Desrumeaux, K. and Fleury, F. and Chames, P. and Baty, D. and Oleinikov, V. and Pluot, M. and Cohen, J. H. and Nabiev, I.

Semiconductor quantum dots for multiplexed bio-detection on solid-state microarrays

Crit Rev Oncol Hematol (2010)

74, 1-15

10.1016/j.critrevonc.2009.04.006

Routes, J. and Costa-Carvalho, B. T. and Grimbacher, B. and Paris, K. and Ochs, H. D. and Filipovich, A. and Hintermeyer, M. and de Melo, K. M. and Workman, S. and Ito, D. and Ye, X. and Bonnet, P. and Li-McLeod, J.

Health-Related Quality of Life and Health Resource Utilization in Patients with Primary Immunodeficiency Disease Prior to and Following 12 Months of Immunoglobulin G Treatment

J Clin Immunol (2016)

36, 450-61

10.1007/s10875-016-0279-0

Roux, L. and Priet, S. and Payrot, N. and Weck, C. and Fournier, M. and Zoulim, F. and Balzarini, J. and Canard, B. and Alvarez, K.

Ester prodrugs of acyclic nucleoside thiophosphonates compared to phosphonates: synthesis, antiviral activity and decomposition study

Eur J Med Chem (2013)

63, 869-81

10.1016/j.ejmech.2013.02.039

Roux, S. and Ligeti, M. and Buisson, D. A. and Rousseau, B. and Cintrat, J. C.

Synthesis of orthogonally protected azahistidine: application to the synthesis of a GHK analogue

Amino Acids (2010)

38, 279-86

10.1007/s00726-009-0248-5

Pellissier, L. P. and Pujol, C. N. and Becker, J. A. and Le Merrer, J.

Delta Opioid Receptors: Learning and Motivation

Handb Exp Pharmacol (2016)

,

10.1007/164_2016_89

Pennerath, F. and Niel, G. and Vismara, P. and Jauffret, P. and Laurenco, C. and Napoli, A.

Graph-mining algorithm for the evaluation of bond formability

J Chem Inf Model (2010)

50, 221-39

10.1021/ci9003909

Peresse, T. and Elie, N. and Touboul, D. and Pham, V. C. and Dumontet, V. and Roussi, F. and Litaudon, M. and Brunelle, A.

Dual Beam Depth Profiling and Imaging with Argon and Bismuth Clusters of Prenylated Stilbenes on Glandular Trichomes of Macaranga vedeliana

Anal Chem (2017)

89, 9247-9252

10.1021/acs.analchem.7b02020

Peresse, T. and Jezequel, G. and Allard, P. M. and Pham, V. C. and Huong, D. T. M. and Blanchard, F. and Bignon, J. and Levaique, H. and Wolfender, J. L. and Litaudon, M. and Roussi, F.

Cytotoxic Prenylated Stilbenes Isolated from Macaranga tanarius

J Nat Prod (2017)

80, 2684-2691

10.1021/acs.jnatprod.7b00409

Perot, S. and Regad, L. and Reynes, C. and Sperandio, O. and Miteva, M. A. and Villoutreix, B. O. and Camproux, A. C.

Insights into an original pocket-ligand pair classification: a promising tool for ligand profile prediction

PLoS One (2013)

8, e63730

10.1371/journal.pone.0063730

Perot, S. and Sperandio, O. and Miteva, M. A. and Camproux, A. C. and Villoutreix, B. O.

Druggable pockets and binding site centric chemical space: a paradigm shift in drug discovery

Drug Discov Today (2010)

15, 656-67

10.1016/j.drudis.2010.05.015

Perri, V. and Rochais, C. and Sopkova-de Oliveira Santos, J. and Legay, R. and Cresteil, T. and Dallemagne, P. and Rault, S.

Hydrogenative desulphurization of thienopyrrolizinones: an easy and selective access to (Z)-phenethylidenepyrrolizinones with in vitro cytotoxic activity

Eur J Med Chem (2010)

45, 1146-50

10.1016/j.ejmech.2009.12.021

Perrin, J. and Mortier, M. and Jacomin, A. C. and Viargues, P. and Thevenon, D. and Fauvarque, M. O.

The nonaspanins TM9SF2 and TM9SF4 regulate the plasma membrane localization and signalling activity of the peptidoglycan recognition protein PGRP-LC in Drosophila

J Innate Immun (2015)

7, 37-46

10.1159/000365112

Peyrat, L. A. and Eparvier, V. and Eydoux, C. and Guillemot, J. C. and Litaudon, M. and Stien, D.

Betulinic Acid, The First Lupane-Type Triterpenoid Isolated from Both a Phomopsis sp. and Its Host Plant Diospyros carbonaria Benoist

Chem Biodivers (2017)

14,

10.1002/cbdv.201600171

Peyrat, L. A. and Eparvier, V. and Eydoux, C. and Guillemot, J. C. and Stien, D. and Litaudon, M.

Chemical diversity and antiviral potential in the pantropical Diospyros genus

Fitoterapia (2016)

112, 9-15

10.1016/j.fitote.2016.04.017

Philippe, R. and Antigny, F. and Buscaglia, P. and Norez, C. and Becq, F. and Frieden, M. and Mignen, O.

SERCA and PMCA pumps contribute to the deregulation of Ca2+ homeostasis in human CF epithelial cells

Biochim Biophys Acta (2015)

1853, 892-903

10.1016/j.bbamcr.2015.01.010

Philippe, R. and Antigny, F. and Buscaglia, P. and Norez, C. and Huguet, F. and Castelbou, C. and Trouve, P. and Becq, F. and Frieden, M. and Ferec, C. and Mignen, O.

Calumenin contributes to ER-Ca(2+) homeostasis in bronchial epithelial cells expressing WT and F508del mutated CFTR and to F508del-CFTR retention

Cell Calcium (2017)

62, 47-59

10.1016/j.ceca.2017.01.011

Piaton, E. and Fabre, M. and Goubin-Versini, I. and Bretz-Grenier, M. F. and Courtade-Saidi, M. and Vincent, S. and Belleannee, G. and Thivolet, F. and Boutonnat, J. and Debaque, H. and Fleury-Feith, J. and Vielh, P. and Cochand-Priollet, B. and pour la Societe francaise de cytologie, clinique and Egele, C. and Bellocq, J. P. and Michiels, J. F. and pour l'Association francaise d'assurance qualite en anatomie et cytologie, pathologiques

[Technical recommendations and best practice guidelines for May-Grunwald-Giemsa staining: literature review and insights from the quality assurance]

Ann Pathol (2015)

35, 294-305

10.1016/j.annpat.2015.05.019

Piaton, E. and Fabre, M. and Goubin-Versini, I. and Bretz-Grenier, M. F. and Courtade-Saidi, M. and Vincent, S. and Belleannee, G. and Thivolet, F. and Boutonnat, J. and Debaque, H. and Fleury-Feith, J. and Vielh, P. and Egele, C. and Bellocq, J. P. and Michiels, J. F. and Cochand-Priollet, B.

Guidelines for May-Grunwald-Giemsa staining in haematology and non-gynaecological cytopathology: recommendations of the French Society of Clinical Cytology (SFCC) and of the French Association for Quality Assurance in Anatomic and Cytologic Pathology (AFA

Cytopathology (2016)

27, 359-68

10.1111/cyt.12323

Pichon, N. and Nallatamby, A. and Blondel, M. and Pichon-Lefievre, F.

Rib destruction with Staphylococcus contiguous abscess after septic pulmonary embolism and tricuspid endocarditis

Intensive Care Med (2018)

44, 1324-1325

10.1007/s00134-018-5090-3

Pigeon, P. and Wang, Y. and Top, S. and Najlaoui, F. and Garcia Alvarez, M. C. and Bignon, J. and McGlinchey, M. J. and Jaouen, G.

A New Series of Succinimido-ferrociphenols and Related Heterocyclic Species Induce Strong Antiproliferative Effects, Especially against Ovarian Cancer Cells Resistant to Cisplatin

J Med Chem (2017)

60, 8358-8368

10.1021/acs.jmedchem.7b00743

Pilger, J. and Mazur, A. and Monecke, P. and Schreuder, H. and Elshorst, B. and Bartoschek, S. and Langer, T. and Schiffer, A. and Krimm, I. and Wegstroth, M. and Lee, D. and Hessler, G. and Wendt, K. U. and Becker, S. and Griesinger, C.

A combination of spin diffusion methods for the determination of protein-ligand complex structural ensembles

Angew Chem Int Ed Engl (2015)

54, 6511-5

10.1002/anie.201500671

Pin, J. P. and Bettler, B.

Organization and functions of mGlu and GABAB receptor complexes

Nature (2016)

540, 60-68

10.1038/nature20566

Piquereau, J. and Caffin, F. and Novotova, M. and Prola, A. and Garnier, A. and Mateo, P. and Fortin, D. and Huynh le, H. and Nicolas, V. and Alavi, M. V. and Brenner, C. and Ventura-Clapier, R. and Veksler, V. and Joubert, F.

Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload

Cardiovasc Res (2012)

94, 408-17

10.1093/cvr/cvs117

Pittolo, S. and Gomez-Santacana, X. and Eckelt, K. and Rovira, X. and Dalton, J. and Goudet, C. and Pin, J. P. and Llobet, A. and Giraldo, J. and Llebaria, A. and Gorostiza, P.

An allosteric modulator to control endogenous G protein-coupled receptors with light

Nat Chem Biol (2014)

10, 813-5

10.1038/nchembio.1612

Polena, H. and Creuzet, J. and Dufies, M. and Sidibe, A. and Khalil-Mgharbel, A. and Salomon, A. and Deroux, A. and Quesada, J. L. and Roelants, C. and Filhol, O. and Cochet, C. and Blanc, E. and Ferlay-Segura, C. and Borchiellini, D. and Ferrero, J. M. and Escudier, B. and Negrier, S. and Pages, G. and Vilgrain, I.

The tyrosine-kinase inhibitor sunitinib targets vascular endothelial (VE)-cadherin: a marker of response to antitumoural treatment in metastatic renal cell carcinoma

Br J Cancer (2018)

118, 1179-1188

10.1038/s41416-018-0054-5

Polishchuk, P. and Madzhidov, T. and Gimadiev, T. and Bodrov, A. and Nugmanov, R. and Varnek, A.

Structure-reactivity modeling using mixture-based representation of chemical reactions

J Comput Aided Mol Des (2017)

31, 829-839

10.1007/s10822-017-0044-3

Polishchuk, P. and Tinkov, O. and Khristova, T. and Ognichenko, L. and Kosinskaya, A. and Varnek, A. and Kuz'min, V.

Structural and Physico-Chemical Interpretation (SPCI) of QSAR Models and Its Comparison with Matched Molecular Pair Analysis

J Chem Inf Model (2016)

56, 1455-69

10.1021/acs.jcim.6b00371

Polishchuk, P. G. and Samoylenko, G. V. and Khristova, T. M. and Krysko, O. L. and Kabanova, T. A. and Kabanov, V. M. and Kornylov, A. Y. and Klimchuk, O. and Langer, T. and Andronati, S. A. and Kuz'min, V. E. and Krysko, A. A. and Varnek, A.

Design, Virtual Screening, and Synthesis of Antagonists of alphaIIbbeta3 as Antiplatelet Agents

J Med Chem (2015)

58, 7681-94

10.1021/acs.jmedchem.5b00865

Portelli, J. and Meurs, A. and Bihel, F. and Hammoud, H. and Schmitt, M. and De Kock, J. and Utard, V. and Humbert, J. P. and Bertin, I. and Buffel, I. and Coppens, J. and Tourwe, D. and Maes, V. and De Prins, A. and Vanhaecke, T. and Massie, A. and Balasubramaniam, A. and Boon, P. and Bourguignon, J. J. and Simonin, F. and Smolders, I.

Neuropeptide FF receptors as novel targets for limbic seizure attenuation

Neuropharmacology (2015)

95, 415-23

10.1016/j.neuropharm.2015.04.030

Potisopon, S. and Ferron, F. and Fattorini, V. and Selisko, B. and Canard, B.

Substrate selectivity of Dengue and Zika virus NS5 polymerase towards 2'-modified nucleotide analogues

Antiviral Res (2017)

140, 25-36

10.1016/j.antiviral.2016.12.021

Potisopon, S. and Priet, S. and Collet, A. and Decroly, E. and Canard, B. and Selisko, B.

The methyltransferase domain of dengue virus protein NS5 ensures efficient RNA synthesis initiation and elongation by the polymerase domain

Nucleic Acids Res (2014)

42, 11642-56

10.1093/nar/gku666

Potisopon, S. and Priet, S. and Collet, A. and Decroly, E. and Canard, B. and Selisko, B.

The methyltransferase domain of dengue virus protein NS5 ensures efficient RNA synthesis initiation and elongation by the polymerase domain

Nucleic Acids Res (2016)

44, 2974

10.1093/nar/gkv1294

Prezeau, L. and Rives, M. L. and Comps-Agrar, L. and Maurel, D. and Kniazeff, J. and Pin, J. P.

Functional crosstalk between GPCRs: with or without oligomerization

Curr Opin Pharmacol (2010)

10, 6-13

10.1016/j.coph.2009.10.009

Priet, S. and Roux, L. and Saez-Ayala, M. and Ferron, F. and Canard, B. and Alvarez, K.

Enzymatic synthesis of acyclic nucleoside thiophosphonate diphosphates: effect of the alpha-phosphorus configuration on HIV-1 RT activity

Antiviral Res (2015)

117, 122-31

10.1016/j.antiviral.2015.03.003

Priet, S. and Zlatev, I. and Barvik, I. and Geerts, K. and Leyssen, P. and Neyts, J. and Dutartre, H. and Canard, B. and Vasseur, J. J. and Morvan, F. and Alvarez, K.

3'-Deoxy phosphoramidate dinucleosides as improved inhibitors of hepatitis C virus subgenomic replicon and NS5B polymerase activity

J Med Chem (2010)

53, 6608-17

10.1021/jm100102v

Primas, N. and Suzanne, P. and Verhaeghe, P. and Hutter, S. and Kieffer, C. and Laget, M. and Cohen, A. and Broggi, J. and Lancelot, J. C. and Lesnard, A. and Dallemagne, P. and Rathelot, P. and Rault, S. and Vanelle, P. and Azas, N.

Synthesis and in vitro evaluation of 4-trichloromethylpyrrolo[1,2-a]quinoxalines as new antiplasmodial agents

Eur J Med Chem (2014)

83, 26-35

10.1016/j.ejmech.2014.06.014

Prudent, R. and Moucadel, V. and Nguyen, C. H. and Barette, C. and Schmidt, F. and Florent, J. C. and Lafanechere, L. and Sautel, C. F. and Duchemin-Pelletier, E. and Spreux, E. and Filhol, O. and Reiser, J. B. and Cochet, C.

Antitumor activity of pyridocarbazole and benzopyridoindole derivatives that inhibit protein kinase CK2

Cancer Res (2010)

70, 9865-74

10.1158/0008-5472.CAN-10-0917

Prudent, R. and Sautel, C. F. and Cochet, C.

Structure-based discovery of small molecules targeting different surfaces of protein-kinase CK2

Biochim Biophys Acta (2010)

1804, 493-8

10.1016/j.bbapap.2009.09.003

Prudent, R. and Sautel, C. F. and Moucadel, V. and Laudet, B. and Filhol, O. and Cochet, C.

In vitro and in vivo assays of protein kinase CK2 activity

Methods Enzymol (2010)

485, 597-610

10.1016/B978-0-12-381296-4.00031-2

Prudent, R. and Soleilhac, E. and Barette, C. and Fauvarque, M. O. and Lafanechere, L.

[Phenotypic screens or one stone to kill two birds: discover the target and its pharmacological regulator]

Med Sci (Paris) (2013)

29, 897-905

10.1051/medsci/20132910018

Prudent, R. and Vassal-Stermann, E. and Nguyen, C. H. and Mollaret, M. and Viallet, J. and Desroches-Castan, A. and Martinez, A. and Barette, C. and Pillet, C. and Valdameri, G. and Soleilhac, E. and Di Pietro, A. and Feige, J. J. and Billaud, M. and Florent, J. C. and Lafanechere, L.

Azaindole derivatives are inhibitors of microtubule dynamics, with anti-cancer and anti-angiogenic activities

Br J Pharmacol (2013)

168, 673-85

10.1111/j.1476-5381.2012.02230.x

Prudent, R. and Vassal-Stermann, E. and Nguyen, C. H. and Pillet, C. and Martinez, A. and Prunier, C. and Barette, C. and Soleilhac, E. and Filhol, O. and Beghin, A. and Valdameri, G. and Honore, S. and Aci-Seche, S. and Grierson, D. and Antonipillai, J. and Li, R. and Di Pietro, A. and Dumontet, C. and Braguer, D. and Florent, J. C. and Knapp, S. and Bernard, O. and Lafanechere, L.

Pharmacological inhibition of LIM kinase stabilizes microtubules and inhibits neoplastic growth

Cancer Res (2012)

72, 4429-39

10.1158/0008-5472.CAN-11-3342

Prunier, C. and Josserand, V. and Vollaire, J. and Beerling, E. and Petropoulos, C. and Destaing, O. and Montemagno, C. and Hurbin, A. and Prudent, R. and de Koning, L. and Kapur, R. and Cohen, P. A. and Albiges-Rizo, C. and Coll, J. L. and van Rheenen, J. and Billaud, M. and Lafanechere, L.

LIM Kinase Inhibitor Pyr1 Reduces the Growth and Metastatic Load of Breast Cancers

Cancer Res (2016)

76, 3541-52

10.1158/0008-5472.CAN-15-1864

Prunier, C. and Kapur, R. and Lafanechere, L.

Targeting LIM kinases in taxane resistant tumors

Oncotarget (2016)

7, 50816-50817

10.18632/oncotarget.10816

Prunier, C. and Prudent, R. and Kapur, R. and Sadoul, K. and Lafanechere, L.

LIM kinases: cofilin and beyond

Oncotarget (2017)

8, 41749-41763

10.18632/oncotarget.16978

Pulido, M. and Roubaud, G. and Cazeau, A. L. and Mahammedi, H. and Vedrine, L. and Joly, F. and Mourey, L. and Pfister, C. and Goberna, A. and Lortal, B. and Bellera, C. and Pourquier, P. and Houede, N.

Safety and efficacy of temsirolimus as second line treatment for patients with recurrent bladder cancer

BMC Cancer (2018)

18, 194

10.1186/s12885-018-4059-5

Putey, A. and Fournet, G. and Lozach, O. and Perrin, L. and Meijer, L. and Joseph, B.

Synthesis and biological evaluation of tetrahydro[1,4]diazepino[1,2-a]indol-1-ones as cyclin-dependent kinase inhibitors

Eur J Med Chem (2014)

83, 617-29

10.1016/j.ejmech.2014.06.063

Quemener, A. and Maillasson, M. and Arzel, L. and Sicard, B. and Vomiandry, R. and Mortier, E. and Dubreuil, D. and Jacques, Y. and Lebreton, J. and Mathe-Allainmat, M.

Discovery of a Small-Molecule Inhibitor of Interleukin 15: Pharmacophore-Based Virtual Screening and Hit Optimization

J Med Chem (2017)

60, 6249-6272

10.1021/acs.jmedchem.7b00485

Queval, C. J. and Song, O. R. and Carralot, J. P. and Saliou, J. M. and Bongiovanni, A. and Deloison, G. and Deboosere, N. and Jouny, S. and Iantomasi, R. and Delorme, V. and Debrie, A. S. and Park, S. J. and Gouveia, J. C. and Tomavo, S. and Brosch, R. and Yoshimura, A. and Yeramian, E. and Brodin, P.

Mycobacterium tuberculosis Controls Phagosomal Acidification by Targeting CISH-Mediated Signaling

Cell Rep (2017)

20, 3188-3198

10.1016/j.celrep.2017.08.101

Queval, C. J. and Song, O. R. and Deboosere, N. and Delorme, V. and Debrie, A. S. and Iantomasi, R. and Veyron-Churlet, R. and Jouny, S. and Redhage, K. and Deloison, G. and Baulard, A. and Chamaillard, M. and Locht, C. and Brodin, P.

STAT3 Represses Nitric Oxide Synthesis in Human Macrophages upon Mycobacterium tuberculosis Infection

Sci Rep (2016)

6, 29297

10.1038/srep29297

Quiedeville, A. and Boulouard, M. and Hamidouche, K. and Da Silva Costa-Aze, V. and Nee, G. and Rochais, C. and Dallemagne, P. and Fabis, F. and Freret, T. and Bouet, V.

Chronic activation of 5-HT4 receptors or blockade of 5-HT6 receptors improve memory performances

Behav Brain Res (2015)

293, 10-7

10.1016/j.bbr.2015.07.020

Quillet, R. and Ayachi, S. and Bihel, F. and Elhabazi, K. and Ilien, B. and Simonin, F.

RF-amide neuropeptides and their receptors in Mammals: Pharmacological properties, drug development and main physiological functions

Pharmacol Ther (2016)

160, 84-132

10.1016/j.pharmthera.2016.02.005

Quillet, R. and Simonin, F.

[The neuropeptide FF: a signal for M1 to M2 type switching in macrophages from the adipose tissue]

Med Sci (Paris) (2018)

34, 27-29

10.1051/medsci/20183401008

Quintard, A. and Cheshmedzhieva, D. and Sanchez Duque Mdel, M. and Gaudel-Siri, A. and Naubron, J. V. and Genisson, Y. and Plaquevent, J. C. and Bugaut, X. and Rodriguez, J. and Constantieux, T.

Origin of the enantioselectivity in organocatalytic Michael additions of beta-ketoamides to alpha,beta-unsaturated carbonyls: a combined experimental, spectroscopic and theoretical study

Chemistry (2015)

21, 778-90

10.1002/chem.201404481

Rabhi, C. and Arcile, G. and Cariel, L. and Lenoir, C. and Bignon, J. and Wdzieczak-Bakala, J. and Ouazzani, J.

Antiangiogenic-Like Properties of Fermented Extracts of Ayurvedic Medicinal Plants

J Med Food (2015)

18, 1065-72

10.1089/jmf.2014.0128

Raffy, Q. and Buisson, D. A. and Cintrat, J. C. and Rousseau, B. and Pin, S. and Renault, J. P.

Carbon-centered radicals can transfer hydrogen atoms between amino acid side chains

Angew Chem Int Ed Engl (2012)

51, 2960-3

10.1002/anie.201108856

Raj, S. and Krishnan, K. and Askew, D. S. and Helynck, O. and Suzanne, P. and Lesnard, A. and Rault, S. and Zeidler, U. and d'Enfert, C. and Latge, J. P. and Munier-Lehmann, H. and Saveanu, C.

The Toxicity of a Novel Antifungal Compound Is Modulated by Endoplasmic Reticulum-Associated Protein Degradation Components

Antimicrob Agents Chemother (2015)

60, 1438-49

10.1128/AAC.02239-15

Rajapakse, C. S. and Lisai, M. and Deregnaucourt, C. and Sinou, V. and Latour, C. and Roy, D. and Schrevel, J. and Sanchez-Delgado, R. A.

Synthesis of New 4-Aminoquinolines and Evaluation of Their In Vitro Activity against Chloroquine-Sensitive and Chloroquine-Resistant Plasmodium falciparum

PLoS One (2015)

10, e0140878

10.1371/journal.pone.0140878

Ramanjooloo, A. and Cresteil, T. and Lebrasse, C. and Beedessee, G. and Oogarah, P. and van Soest, R. W. and Marie, D. E.

alpha-Glucosidase inhibitory activity of marine sponges collected in Mauritius waters

Nat Prod Res (2015)

29, 383-7

10.1080/14786419.2014.945173

Raux, B. and Voitovich, Y. and Derviaux, C. and Lugari, A. and Rebuffet, E. and Milhas, S. and Priet, S. and Roux, T. and Trinquet, E. and Guillemot, J. C. and Knapp, S. and Brunel, J. M. and Fedorov, A. Y. and Collette, Y. and Roche, P. and Betzi, S. and Combes, S. and Morelli, X.

Exploring Selective Inhibition of the First Bromodomain of the Human Bromodomain and Extra-terminal Domain (BET) Proteins

J Med Chem (2016)

59, 1634-41

10.1021/acs.jmedchem.5b01708

Ray, A. M. and Schaffner, F. and Janouskova, H. and Noulet, F. and Rognan, D. and Lelong-Rebel, I. and Choulier, L. and Blandin, A. F. and Lehmann, M. and Martin, S. and Kapp, T. and Neubauer, S. and Rechenmacher, F. and Kessler, H. and Dontenwill, M.

Single cell tracking assay reveals an opposite effect of selective small non-peptidic alpha5beta1 or alphavbeta3/beta5 integrin antagonists in U87MG glioma cells

Biochim Biophys Acta (2014)

1840, 2978-87

10.1016/j.bbagen.2014.04.024

Rederstorff, M. and Castets, P. and Arbogast, S. and Laine, J. and Vassilopoulos, S. and Beuvin, M. and Dubourg, O. and Vignaud, A. and Ferry, A. and Krol, A. and Allamand, V. and Guicheney, P. and Ferreiro, A. and Lescure, A.

Increased muscle stress-sensitivity induced by selenoprotein N inactivation in mouse: a mammalian model for SEPN1-related myopathy

PLoS One (2011)

6, e23094

10.1371/journal.pone.0023094

Regenass, P. and Bosc, D. and Riche, S. and Gizzi, P. and Hibert, M. and Karmazin, L. and Ganesan, A. and Bonnet, D.

Comparative Study of the Synthesis and Structural and Physicochemical Properties of Diketopiperazines vs Aza-diketopiperazines

J Org Chem (2017)

82, 3239-3244

10.1021/acs.joc.6b02895

Regenass, P. and Margathe, J. F. and Mann, A. and Suffert, J. and Hibert, M. and Girard, N. and Bonnet, D.

Diastereoselective synthesis of novel aza-diketopiperazines via a domino cyclohydrocarbonylation/addition process

Chem Commun (Camb) (2014)

50, 9657-60

10.1039/c4cc03660c

Regenass, P. and Riche, S. and Peron, F. and Rognan, D. and Hibert, M. and Girard, N. and Bonnet, D.

A step-economical multicomponent synthesis of 3D-shaped aza-diketopiperazines and their drug-like chemical space analysis

Org Biomol Chem (2016)

14, 8859-8863

10.1039/c6ob01434h

Renard, B. L. and Boucherle, B. and Maurin, B. and Molina, M. C. and Norez, C. and Becq, F. and Decout, J. L.

An expeditious access to 5-pyrimidinol derivatives from cyclic methylglyoxal diadducts, formation of argpyrimidines under physiological conditions and discovery of new CFTR inhibitors

Eur J Med Chem (2011)

46, 1935-41

10.1016/j.ejmech.2011.02.037

Renaud, V. and Godefroy, E. and Larrieu, P. and Fleury, F. and Jotereau, F. and Guilloux, Y.

Folding of matrix metalloproteinase-2 prevents endogenous generation of MHC class-I restricted epitope

PLoS One (2010)

5, e11894

10.1371/journal.pone.0011894

Renko, D. and Provot, O. and Rasolofonjatovo, E. and Bignon, J. and Rodrigo, J. and Dubois, J. and Brion, J. D. and Hamze, A. and Alami, M.

Rapid synthesis of 4-arylchromenes from ortho-substituted alkynols: A versatile access to restricted isocombretastatin A-4 analogues as antitumor agents

Eur J Med Chem (2015)

90, 834-44

10.1016/j.ejmech.2014.12.024

Rerole, A. L. and Gobbo, J. and De Thonel, A. and Schmitt, E. and Pais de Barros, J. P. and Hammann, A. and Lanneau, D. and Fourmaux, E. and Demidov, O. N. and Micheau, O. and Lagrost, L. and Colas, P. and Kroemer, G. and Garrido, C.

Peptides and aptamers targeting HSP70: a novel approach for anticancer chemotherapy

Cancer Res (2011)

71, 484-95

10.1158/0008-5472.CAN-10-1443

Rey, J. and Deschavanne, P. and Tuffery, P.

BactPepDB: a database of predicted peptides from a exhaustive survey of complete prokaryote genomes

Database (Oxford) (2014)

2014,

10.1093/database/bau106

Rey-Rodriguez, R. and Retailleau, P. and Bonnet, P. and Gillaizeau, I.

Iron-catalyzed trifluoromethylation of enamide

Chemistry (2015)

21, 3572-5

10.1002/chem.201406333

Reynes, C. and Host, H. and Camproux, A. C. and Laconde, G. and Leroux, F. and Mazars, A. and Deprez, B. and Fahraeus, R. and Villoutreix, B. O. and Sperandio, O.

Designing focused chemical libraries enriched in protein-protein interaction inhibitors using machine-learning methods

PLoS Comput Biol (2010)

6, e1000695

10.1371/journal.pcbi.1000695

Ribeiro, N. and Thuaud, F. and Bernard, Y. and Gaiddon, C. and Cresteil, T. and Hild, A. and Hirsch, E. C. and Michel, P. P. and Nebigil, C. G. and Desaubry, L.

Flavaglines as potent anticancer and cytoprotective agents

J Med Chem (2012)

55, 10064-73

10.1021/jm301201z

Ripoll, M. and Neuberg, P. and Kichler, A. and Tounsi, N. and Wagner, A. and Remy, J. S.

pH-Responsive Nanometric Polydiacetylenic Micelles Allow for Efficient Intracellular siRNA Delivery

ACS Appl Mater Interfaces (2016)

8, 30665-30670

10.1021/acsami.6b09365

Riva, L. and Song, O. R. and Prentoe, J. and Helle, F. and L'Homme, L. and Gattolliat, C. H. and Vandeputte, A. and Feneant, L. and Belouzard, S. and Baumert, T. F. and Asselah, T. and Bukh, J. and Brodin, P. and Cocquerel, L. and Rouille, Y. and Dubuisson, J.

Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry

J Virol (2018)

92,

10.1128/JVI.01982-17

Rivat, C. and Sar, C. and Mechaly, I. and Leyris, J. P. and Diouloufet, L. and Sonrier, C. and Philipson, Y. and Lucas, O. and Mallie, S. and Jouvenel, A. and Tassou, A. and Haton, H. and Venteo, S. and Pin, J. P. and Trinquet, E. and Charrier-Savournin, F. and Mezghrani, A. and Joly, W. and Mion, J. and Schmitt, M. and Pattyn, A. and Marmigere, F. and Sokoloff, P. and Carroll, P. and Rognan, D. and Valmier, J.

Inhibition of neuronal FLT3 receptor tyrosine kinase alleviates peripheral neuropathic pain in mice

Nat Commun (2018)

9, 1042

10.1038/s41467-018-03496-2

Rives, A. and Baudoin-Dehoux, C. and Saffon, N. and Andrieu-Abadie, N. and Genisson, Y.

Asymmetric synthesis and cytotoxic activity of isomeric phytosphingosine derivatives

Org Biomol Chem (2011)

9, 8163-70

10.1039/c1ob06195j

Rives, A. and Ladeira, S. and Levade, T. and Andrieu-Abadie, N. and Genisson, Y.

Synthesis of cytotoxic aza analogues of jaspine B

J Org Chem (2010)

75, 7920-3

10.1021/jo1014239

Rizza, P. and Pellegrino, M. and Caruso, A. and Iacopetta, D. and Sinicropi, M. S. and Rault, S. and Lancelot, J. C. and El-Kashef, H. and Lesnard, A. and Rochais, C. and Dallemagne, P. and Saturnino, C. and Giordano, F. and Catalano, S. and Ando, S.

3-(Dipropylamino)-5-hydroxybenzofuro[2,3-f]quinazolin-1(2H)-one (DPA-HBFQ-1) plays an inhibitory role on breast cancer cell growth and progression

Eur J Med Chem (2016)

107, 275-87

10.1016/j.ejmech.2015.11.004

Rochais, C. and Cresteil, T. and Perri, V. and Jouanne, M. and Lesnard, A. and Rault, S. and Dallemagne, P.

MR22388, a novel anti-cancer agent with a strong FLT-3 ITD kinase affinity

Cancer Lett (2013)

331, 92-8

10.1016/j.canlet.2012.12.017

Rochais, C. and Lecoutey, C. and Gaven, F. and Giannoni, P. and Hamidouche, K. and Hedou, D. and Dubost, E. and Genest, D. and Yahiaoui, S. and Freret, T. and Bouet, V. and Dauphin, F. and Sopkova de Oliveira Santos, J. and Ballandonne, C. and Corvaisier, S. and Malzert-Freon, A. and Legay, R. and Boulouard, M. and Claeysen, S. and Dallemagne, P.

Novel multitarget-directed ligands (MTDLs) with acetylcholinesterase (AChE) inhibitory and serotonergic subtype 4 receptor (5-HT4R) agonist activities as potential agents against Alzheimer's disease: the design of donecopride

J Med Chem (2015)

58, 3172-87

10.1021/acs.jmedchem.5b00115

Rochais, C. and Rault, S. and Dallemagne, P.

Intramolecular cyclisation of beta-aryl-beta-amino acids in the design of novel heterocyclic systems with therapeutic interest: an unfailing source of diversity

Curr Med Chem (2010)

17, 4342-69

Roche, M. and Salim, S. M. and Bignon, J. and Levaique, H. and Brion, J. D. and Alami, M. and Hamze, A.

Palladium-Catalyzed One-Pot Reaction of Hydrazones, Dihaloarenes, and Organoboron Reagents: Synthesis and Cytotoxic Activity of 1,1-Diarylethylene Derivatives

J Org Chem (2015)

80, 6715-27

10.1021/acs.joc.5b00880

Rode, B. and Dirami, T. and Bakouh, N. and Rizk-Rabin, M. and Norez, C. and Lhuillier, P. and Lores, P. and Jollivet, M. and Melin, P. and Zvetkova, I. and Bienvenu, T. and Becq, F. and Planelles, G. and Edelman, A. and Gacon, G. and Toure, A.

The testis anion transporter TAT1 (SLC26A8) physically and functionally interacts with the cystic fibrosis transmembrane conductance regulator channel: a potential role during sperm capacitation

Hum Mol Genet (2012)

21, 1287-98

10.1093/hmg/ddr558

Roeckel, L. A. and Le Coz, G. M. and Gaveriaux-Ruff, C. and Simonin, F.

Opioid-induced hyperalgesia: Cellular and molecular mechanisms

Neuroscience (2016)

338, 160-182

10.1016/j.neuroscience.2016.06.029

Roeckel, L. A. and Utard, V. and Reiss, D. and Mouheiche, J. and Maurin, H. and Robe, A. and Audouard, E. and Wood, J. N. and Goumon, Y. and Simonin, F. and Gaveriaux-Ruff, C.

Morphine-induced hyperalgesia involves mu opioid receptors and the metabolite morphine-3-glucuronide

Sci Rep (2017)

7, 10406

10.1038/s41598-017-11120-4

Roelants, C. and Giacosa, S. and Pillet, C. and Bussat, R. and Champelovier, P. and Bastien, O. and Guyon, L. and Arnoux, V. and Cochet, C. and Filhol, O.

Combined inhibition of PI3K and Src kinases demonstrates synergistic therapeutic efficacy in clear-cell renal carcinoma

Oncotarget (2018)

9, 30066-30078

10.18632/oncotarget.25700

Rognan, D.

Fragment-based approaches and computer-aided drug discovery

Top Curr Chem (2012)

317, 201-22

10.1007/128_2011_182

Rognan, D.

Towards the Next Generation of Computational Chemogenomics Tools

Mol Inform (2013)

32, 1029-34

10.1002/minf.201300054

Rognan, D.

The impact of in silico screening in the discovery of novel and safer drug candidates

Pharmacol Ther (2017)

175, 47-66

10.1016/j.pharmthera.2017.02.034

Rovira, X. and Harrak, Y. and Trapero, A. and Gonzalez-Bulnes, P. and Malhaire, F. and Pin, J. P. and Goudet, C. and Giraldo, J. and Llebaria, A.

Exploring the active conformation of cyclohexane carboxylate positive allosteric modulators of the type 4 metabotropic glutamate receptor

ChemMedChem (2014)

9, 2685-98

10.1002/cmdc.201402190

Rovira, X. and Malhaire, F. and Scholler, P. and Rodrigo, J. and Gonzalez-Bulnes, P. and Llebaria, A. and Pin, J. P. and Giraldo, J. and Goudet, C.

Overlapping binding sites drive allosteric agonism and positive cooperativity in type 4 metabotropic glutamate receptors

FASEB J (2015)

29, 116-30

10.1096/fj.14-257287

Rovira, X. and Trapero, A. and Pittolo, S. and Zussy, C. and Faucherre, A. and Jopling, C. and Giraldo, J. and Pin, J. P. and Gorostiza, P. and Goudet, C. and Llebaria, A.

OptoGluNAM4.1, a Photoswitchable Allosteric Antagonist for Real-Time Control of mGlu4 Receptor Activity

Cell Chem Biol (2016)

23, 929-34

10.1016/j.chembiol.2016.06.013

Ruat, M. and Hoch, L. and Faure, H. and Rognan, D.

[Structure of the Smoothened receptor]

Med Sci (Paris) (2013)

29, 855-60

10.1051/medsci/20132910012

Ruat, M. and Hoch, L. and Faure, H. and Rognan, D.

Targeting of Smoothened for therapeutic gain

Trends Pharmacol Sci (2014)

35, 237-46

10.1016/j.tips.2014.03.002

Rudinger-Thirion, J. and Lescure, A. and Paulus, C. and Frugier, M.

Misfolded human tRNA isodecoder binds and neutralizes a 3' UTR-embedded Alu element

Proc Natl Acad Sci U S A (2011)

108, E794-802

10.1073/pnas.1103698108

Ruggiu, F. and Gizzi, P. and Galzi, J. L. and Hibert, M. and Haiech, J. and Baskin, I. and Horvath, D. and Marcou, G. and Varnek, A.

Quantitative structure-property relationship modeling: a valuable support in high-throughput screening quality control

Anal Chem (2014)

86, 2510-20

10.1021/ac403544k

Ruggiu, F. and Marcou, G. and Varnek, A. and Horvath, D.

ISIDA Property-Labelled Fragment Descriptors

Mol Inform (2010)

29, 855-68

10.1002/minf.201000099

Ruggiu, F. and Solov'ev, V. and Marcou, G. and Horvath, D. and Graton, J. and Le Questel, J. Y. and Varnek, A.

Individual Hydrogen-Bond Strength QSPR Modelling with ISIDA Local Descriptors: a Step Towards Polyfunctional Molecules

Mol Inform (2014)

33, 477-87

10.1002/minf.201400032

Ruiz, J. and Azema, J. and Payrastre, C. and Baltas, M. and Tuccio, B. and Vial, H. and Andre-Barres, C.

Antimalarial bicyclic peroxides belonging to the G-factor family: mechanistic aspects of their formation and iron (II) induced reduction

Curr Top Med Chem (2014)

14, 1668-83

Ruiz, M. and Courilleau, D. and Jullian, J. C. and Fortin, D. and Ventura-Clapier, R. and Blondeau, J. P. and Garnier, A.

A cardiac-specific robotized cellular assay identified families of human ligands as inducers of PGC-1alpha expression and mitochondrial biogenesis

PLoS One (2012)

7, e46753

10.1371/journal.pone.0046753

Rutkowska-Wlodarczyk, I. and Aller, M. I. and Valbuena, S. and Bologna, J. C. and Prezeau, L. and Lerma, J.

A proteomic analysis reveals the interaction of GluK1 ionotropic kainate receptor subunits with Go proteins

J Neurosci (2015)

35, 5171-9

10.1523/JNEUROSCI.5059-14.2015

Sabourdy, F. and Mourey, L. and Le Trionnaire, E. and Bednarek, N. and Caillaud, C. and Chaix, Y. and Delrue, M. A. and Dusser, A. and Froissart, R. and Garnotel, R. and Guffon, N. and Megarbane, A. and Ogier de Baulny, H. and Pedespan, J. M. and Pichard, S. and Valayannopoulos, V. and Verloes, A. and Levade, T.

Natural disease history and characterisation of SUMF1 molecular defects in ten unrelated patients with multiple sulfatase deficiency

Orphanet J Rare Dis (2015)

10, 31

10.1186/s13023-015-0244-7

Saez-Ayala, M. and Yekwa, E. L. and Carcelli, M. and Canard, B. and Alvarez, K. and Ferron, F.

Crystal structures of Lymphocytic choriomeningitis virus endonuclease domain complexed with diketo-acid ligands

IUCrJ (2018)

5, 223-235

10.1107/S2052252518001021

Sagnol, S. and Yang, Y. and Bessin, Y. and Allemand, F. and Hapkova, I. and Notarnicola, C. and Guichou, J. F. and Faure, S. and Labesse, G. and de Santa Barbara, P.

Homodimerization of RBPMS2 through a new RRM-interaction motif is necessary to control smooth muscle plasticity

Nucleic Acids Res (2014)

42, 10173-84

10.1093/nar/gku692

Saidani, N. and Botte, C. Y. and Deligny, M. and Bonneau, A. L. and Reader, J. and Lasselin, R. and Merer, G. and Niepceron, A. and Brossier, F. and Cintrat, J. C. and Rousseau, B. and Birkholtz, L. M. and Cesbron-Delauw, M. F. and Dubremetz, J. F. and Mercier, C. and Vial, H. and Lopez, R. and Marechal, E.

Discovery of compounds blocking the proliferation of Toxoplasma gondii and Plasmodium falciparum in a chemical space based on piperidinyl-benzimidazolone analogs

Antimicrob Agents Chemother (2014)

58, 2586-97

10.1128/AAC.01445-13

Thebault, C. J. and Ramniceanu, G. and Michel, A. and Beauvineau, C. and Girard, C. and Seguin, J. and Mignet, N. and Menager, C. and Doan, B. T.

In Vivo Evaluation of Magnetic Targeting in Mice Colon Tumors with Ultra-Magnetic Liposomes Monitored by MRI

Mol Imaging Biol (2018)

,

10.1007/s11307-018-1238-3

Thevenet, P. and Rey, J. and Moroy, G. and Tuffery, P.

De novo peptide structure prediction: an overview

Methods Mol Biol (2015)

1268, 1-13

10.1007/978-1-4939-2285-7_1

Thevenet, P. and Shen, Y. and Maupetit, J. and Guyon, F. and Derreumaux, P. and Tuffery, P.

PEP-FOLD: an updated de novo structure prediction server for both linear and disulfide bonded cyclic peptides

Nucleic Acids Res (2012)

40, W288-93

10.1093/nar/gks419

Thouennon, E. and Pierre, A. and Tanguy, Y. and Guillemot, J. and Manecka, D. L. and Guerin, M. and Ouafik, L. and Muresan, M. and Klein, M. and Bertherat, J. and Lefebvre, H. and Plouin, P. F. and Yon, L. and Anouar, Y.

Expression of trophic amidated peptides and their receptors in benign and malignant pheochromocytomas: high expression of adrenomedullin RDC1 receptor and implication in tumoral cell survival

Endocr Relat Cancer (2010)

17, 637-51

10.1677/ERC-10-0109

Thouvenot, P. and Ben Yamin, B. and Fourriere, L. and Lescure, A. and Boudier, T. and Del Nery, E. and Chauchereau, A. and Goldgar, D. E. and Houdayer, C. and Stoppa-Lyonnet, D. and Nicolas, A. and Millot, G. A.

Functional Assessment of Genetic Variants with Outcomes Adapted to Clinical Decision-Making

PLoS Genet (2016)

12, e1006096

10.1371/journal.pgen.1006096

Thouvenot, P. and Fourriere, L. and Dardillac, E. and Ben Yamin, B. and Lescure, A. and Lejour, V. and Heiligenstein, X. and Boule, J. B. and Romao, M. and Raposo-Benedetti, G. and Lopez, B. S. and Nicolas, A. and Millot, G. A.

Yeast cells reveal the misfolding and the cellular mislocalization of the human BRCA1 protein

J Cell Sci (2016)

129, 4366-4378

10.1242/jcs.192880

Thuaud, F. and Ribeiro, N. and Gaiddon, C. and Cresteil, T. and Desaubry, L.

Novel flavaglines displaying improved cytotoxicity

J Med Chem (2011)

54, 411-5

10.1021/jm101318b

Tiwari, K. N. and Monserrat, J. P. and Hequet, A. and Ganem-Elbaz, C. and Cresteil, T. and Jaouen, G. and Vessieres, A. and Hillard, E. A. and Jolivalt, C.

In vitro inhibitory properties of ferrocene-substituted chalcones and aurones on bacterial and human cell cultures

Dalton Trans (2012)

41, 6451-7

10.1039/c2dt12180h

Tora, A. S. and Rovira, X. and Dione, I. and Bertrand, H. O. and Brabet, I. and De Koninck, Y. and Doyon, N. and Pin, J. P. and Acher, F. and Goudet, C.

Allosteric modulation of metabotropic glutamate receptors by chloride ions

FASEB J (2015)

29, 4174-88

10.1096/fj.14-269746

Traore, T. and Delacour, L. and Garcia-Argote, S. and Berthault, P. and Cintrat, J. C. and Rousseau, B.

Scalable synthesis of cryptophane-1.1.1 and its functionalization

Org Lett (2010)

12, 960-2

10.1021/ol902952h

Treguier, B. and Lawson, M. and Bernadat, G. and Bignon, J. and Dubois, J. and Brion, J. D. and Alami, M. and Hamze, A.

Synthesis of a 3-(alpha-styryl)benzo[b]-thiophene library via bromocyclization of alkynes and palladium-catalyzed to sylhydrazones cross-couplings: evaluation as antitubulin agents

ACS Comb Sci (2014)

16, 702-10

10.1021/co500115b

Trepiccione, F. and Soukaseum, C. and Baudrie, V. and Kumai, Y. and Teulon, J. and Villoutreix, B. and Corniere, N. and Wangemann, P. and Griffith, A. J. and Byung Choi, Y. and Hadchouel, J. and Chambrey, R. and Eladari, D.

Acute genetic ablation of pendrin lowers blood pressure in mice

Nephrol Dial Transplant (2017)

32, 1137-1145

10.1093/ndt/gfw393

Trofimov, V. and Costa-Gouveia, J. and Hoffmann, E. and Brodin, P.

Host-pathogen systems for early drug discovery against tuberculosis

Curr Opin Microbiol (2017)

39, 143-151

10.1016/j.mib.2017.11.017

Trovaslet-Leroy, M. and Jolivalt, C. and Froment, M. T. and Brasme, B. and Lefebvre, B. and Daveloose, D. and Nachon, F. and Masson, P.

Application of laccase-mediator system (LMS) for the degradation of organophosphorus compounds

Chem Biol Interact (2010)

187, 393-6

10.1016/j.cbi.2010.02.001

Sakanyan, V. and Angelini, M. and Le Bechec, M. and Lecocq, M. F. and Benaiteau, F. and Rousseau, B. and Gyulkhandanyan, A. and Gyulkhandanyan, L. and Loge, C. and Reiter, E. and Roussakis, C. and Fleury, F.

Screening and discovery of nitro-benzoxadiazole compounds activating epidermal growth factor receptor (EGFR) in cancer cells

Sci Rep (2014)

4, 3977

10.1038/srep03977

Sakanyan, V. and Hulin, P. and Alves de Sousa, R. and Silva, V. A. and Hambardzumyan, A. and Nedellec, S. and Tomasoni, C. and Loge, C. and Pineau, C. and Roussakis, C. and Fleury, F. and Artaud, I.

Activation of EGFR by small compounds through coupling the generation of hydrogen peroxide to stable dimerization of Cu/Zn SOD1

Sci Rep (2016)

6, 21088

10.1038/srep21088

Sala, A. J. and Bordes, P. and Ayala, S. and Slama, N. and Tranier, S. and Coddeville, M. and Cirinesi, A. M. and Castanie-Cornet, M. P. and Mourey, L. and Genevaux, P.

Directed evolution of SecB chaperones toward toxin-antitoxin systems

Proc Natl Acad Sci U S A (2017)

114, 12584-12589

10.1073/pnas.1710456114

Saladin, A. and Rey, J. and Thevenet, P. and Zacharias, M. and Moroy, G. and Tuffery, P.

PEP-SiteFinder: a tool for the blind identification of peptide binding sites on protein surfaces

Nucleic Acids Res (2014)

42, W221-6

10.1093/nar/gku404

Sallustrau, A. and Bregant, S. and Chollet, C. and Audisio, D. and Taran, F.

Scalable and practical synthesis of clickable Cu-chelating azides

Chem Commun (Camb) (2017)

53, 7890-7893

10.1039/c7cc03247a

Salma, Y. and Ballereau, S. and Maaliki, C. and Ladeira, S. and Andrieu-Abadie, N. and Genisson, Y.

Flexible and enantioselective access to jaspine B and biologically active chain-modified analogues thereof

Org Biomol Chem (2010)

8, 3227-43

10.1039/c004218h

Salmi-Smail, C. and Fabre, A. and Dequiedt, F. and Restouin, A. and Castellano, R. and Garbit, S. and Roche, P. and Morelli, X. and Brunel, J. M. and Collette, Y.

Modified cap group suberoylanilide hydroxamic acid histone deacetylase inhibitor derivatives reveal improved selective antileukemic activity

J Med Chem (2010)

53, 3038-47

10.1021/jm901358y

Salzano, G. and Wankar, J. and Ottani, S. and Villemagne, B. and Baulard, A. R. and Willand, N. and Brodin, P. and Manet, I. and Gref, R.

Cyclodextrin-based nanocarriers containing a synergic drug combination: A potential formulation for pulmonary administration of antitubercular drugs

Int J Pharm (2017)

531, 577-587

10.1016/j.ijpharm.2017.05.030

Sanchez Duque Mdel, M. and Basle, O. and Genisson, Y. and Plaquevent, J. C. and Bugaut, X. and Constantieux, T. and Rodriguez, J.

Enantioselective organocatalytic multicomponent synthesis of 2,6-diazabicyclo[2.2.2]octanones

Angew Chem Int Ed Engl (2013)

52, 14143-6

10.1002/anie.201306656

Sanchez Duque Mdel, M. and Basle, O. and Isambert, N. and Gaudel-Siri, A. and Genisson, Y. and Plaquevent, J. C. and Rodriguez, J. and Constantieux, T.

A cooperative participation of the amido group in the organocatalytic construction of all-carbon quaternary stereocenters by Michael addition with beta-ketoamides

Org Lett (2011)

13, 3296-9

10.1021/ol200924e

Sane, S. and Richter, K. and Rubenwolf, S. and Matschke, N. J. and Jolivalt, C. and Madzak, C. and Zengerle, R. and Gescher, J. and Kerzenmacher, S.

Using planktonic microorganisms to supply the unpurified multi-copper oxidases laccase and copper efflux oxidases at a biofuel cell cathode

Bioresour Technol (2014)

158, 231-8

10.1016/j.biortech.2014.02.038

Santi, M. D. and Paulino Zunini, M. and Vera, B. and Bouzidi, C. and Dumontet, V. and Abin-Carriquiry, A. and Grougnet, R. and Ortega, M. G.

Xanthine oxidase inhibitory activity of natural and hemisynthetic flavonoids from Gardenia oudiepe (Rubiaceae) in vitro and molecular docking studies

Eur J Med Chem (2018)

143, 577-582

10.1016/j.ejmech.2017.11.071

Santos, C. and Fleury, L. and Rodriguez, F. and Markus, J. and Berkes, D. and Daich, A. and Ausseil, F. and Baudoin-Dehoux, C. and Ballereau, S. and Genisson, Y.

The CERT antagonist HPA-12: first practical synthesis and individual binding evaluation of the four stereoisomers

Bioorg Med Chem (2015)

23, 2004-9

10.1016/j.bmc.2015.03.019

Santos, C. and Rogriguez, F. and Garcia, V. and Moravcikova, D. and Berkes, D. and Daich, A. and Levade, T. and Baudoin-Dehoux, C. and Ballereau, S. and Genisson, Y.

Identification of novel CERT ligands as potential ceramide trafficking inhibitors

Chembiochem (2014)

15, 2522-8

10.1002/cbic.201402366

Santos, C. and Stauffert, F. and Ballereau, S. and Dehoux, C. and Rodriguez, F. and Bodlenner, A. and Compain, P. and Genisson, Y.

Iminosugar-based ceramide mimicry for the design of new CERT START domain ligands

Bioorg Med Chem (2017)

25, 1984-1989

10.1016/j.bmc.2017.02.026

Santos, C. N. and Gomes, A. and Oudot, C. and Dias-Pedroso, D. and Rodriguez-Mateos, A. and Vieira, H. L. A. and Brenner, C.

Pure polyphenols applications for cardiac health and disease

Curr Pharm Des (2018)

,

10.2174/1381612824666180608102344

Sari, O. and Roy, V. and Metifiot, M. and Marchand, C. and Pommier, Y. and Bourg, S. and Bonnet, P. and Schinazi, R. F. and Agrofoglio, L. A.

Synthesis of dihydropyrimidine alpha,gamma-diketobutanoic acid derivatives targeting HIV integrase

Eur J Med Chem (2015)

104, 127-38

10.1016/j.ejmech.2015.09.015

Sarkis, M. and Tran, D. N. and Kolb, S. and Miteva, M. A. and Villoutreix, B. O. and Garbay, C. and Braud, E.

Design and synthesis of novel bis-thiazolone derivatives as micromolar CDC25 phosphatase inhibitors: effect of dimerisation on phosphatase inhibition

Bioorg Med Chem Lett (2012)

22, 7345-50

10.1016/j.bmcl.2012.10.072

Sayes, F. and Blanc, C. and Ates, L. S. and Deboosere, N. and Orgeur, M. and Le Chevalier, F. and Groschel, M. I. and Frigui, W. and Song, O. R. and Lo-Man, R. and Brossier, F. and Sougakoff, W. and Bottai, D. and Brodin, P. and Charneau, P. and Brosch, R. and Majlessi, L.

Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors

Cell Rep (2018)

23, 1072-1084

10.1016/j.celrep.2018.03.125

Schaeffer, E. and Flacher, V. and Neuberg, P. and Hoste, A. and Brulefert, A. and Fauny, J. D. and Wagner, A. and Mueller, C. G.

Inhibition of dengue virus infection by mannoside glycolipid conjugates

Antiviral Res (2018)

154, 116-123

10.1016/j.antiviral.2018.04.005

Schauer, K. and Grossier, J. P. and Duong, T. and Chapuis, V. and Degot, S. and Lescure, A. and Del Nery, E. and Goud, B.

A novel organelle map framework for high-content cell morphology analysis in high throughput

J Biomol Screen (2014)

19, 317-24

10.1177/1087057113497399

Schneider, S. and Ftouni, H. and Niu, S. and Schmitt, M. and Simonin, F. and Bihel, F.

Rapid and scalable synthesis of innovative unnatural alpha,beta or gamma-amino acids functionalized with tertiary amines on their side-chains

Org Biomol Chem (2015)

13, 7020-6

10.1039/c5ob00828j

Scholler, P. and Moreno-Delgado, D. and Lecat-Guillet, N. and Doumazane, E. and Monnier, C. and Charrier-Savournin, F. and Fabre, L. and Chouvet, C. and Soldevila, S. and Lamarque, L. and Donsimoni, G. and Roux, T. and Zwier, J. M. and Trinquet, E. and Rondard, P. and Pin, J. P.

HTS-compatible FRET-based conformational sensors clarify membrane receptor activation

Nat Chem Biol (2017)

13, 372-380

10.1038/nchembio.2286

Scholler, P. and Nevoltris, D. and de Bundel, D. and Bossi, S. and Moreno-Delgado, D. and Rovira, X. and Moller, T. C. and El Moustaine, D. and Mathieu, M. and Blanc, E. and McLean, H. and Dupuis, E. and Mathis, G. and Trinquet, E. and Daniel, H. and Valjent, E. and Baty, D. and Chames, P. and Rondard, P. and Pin, J. P.

Allosteric nanobodies uncover a role of hippocampal mGlu2 receptor homodimers in contextual fear consolidation

Nat Commun (2017)

8, 1967

10.1038/s41467-017-01489-1

Scholler, P. and Zwier, J. M. and Trinquet, E. and Rondard, P. and Pin, J. P. and Prezeau, L. and Kniazeff, J.

Time-resolved Forster resonance energy transfer-based technologies to investigate G protein-coupled receptor machinery: high-throughput screening assays and future development

Prog Mol Biol Transl Sci (2013)

113, 275-312

10.1016/B978-0-12-386932-6.00007-7

Seah, S. and Low, I. C. and Hirpara, J. L. and Sachaphibulkij, K. and Kroemer, G. and Brenner, C. and Pervaiz, S.

Activation of surrogate death receptor signaling triggers peroxynitrite-dependent execution of cisplatin-resistant cancer cells

Cell Death Dis (2015)

6, e1926

10.1038/cddis.2015.299

Secher, T. and Shima, A. and Hinsinger, K. and Cintrat, J. C. and Johannes, L. and Barbier, J. and Gillet, D. and Oswald, E.

Retrograde Trafficking Inhibitor of Shiga Toxins Reduces Morbidity and Mortality of Mice Infected with Enterohemorrhagic Escherichia coli

Antimicrob Agents Chemother (2015)

59, 5010-3

10.1128/AAC.00455-15

Seigneuric, R. and Gobbo, J. and Colas, P. and Garrido, C.

Targeting cancer with peptide aptamers

Oncotarget (2011)

2, 557-61

10.18632/oncotarget.297

Selisko, B. and Papageorgiou, N. and Ferron, F. and Canard, B.

Structural and Functional Basis of the Fidelity of Nucleotide Selection by Flavivirus RNA-Dependent RNA Polymerases

Viruses (2018)

10,

10.3390/v10020059

Selisko, B. and Peyrane, F. F. and Canard, B. and Alvarez, K. and Decroly, E.

Biochemical characterization of the (nucleoside-2'O)-methyltransferase activity of dengue virus protein NS5 using purified capped RNA oligonucleotides (7Me)GpppAC(n) and GpppAC(n)

J Gen Virol (2010)

91, 112-21

10.1099/vir.0.015511-0

Selisko, B. and Potisopon, S. and Agred, R. and Priet, S. and Varlet, I. and Thillier, Y. and Sallamand, C. and Debart, F. and Vasseur, J. J. and Canard, B.

Molecular basis for nucleotide conservation at the ends of the dengue virus genome

PLoS Pathog (2012)

8, e1002912

10.1371/journal.ppat.1002912

Selisko, B. and Wang, C. and Harris, E. and Canard, B.

Regulation of Flavivirus RNA synthesis and replication

Curr Opin Virol (2014)

9, 74-83

10.1016/j.coviro.2014.09.011

Selmeczi, K. and Gizzi, P. and Champmartin, D. and Rubini, P. and Aubert, E. and Dahaoui, S. and Henry, B.

Nickel(II)-dipeptidoamine-based tetrameric complex: structural study in solution and in solid state

Inorg Chem (2010)

49, 8222-9

10.1021/ic101167f

Selvam, C. and Lemasson, I. A. and Brabet, I. and Oueslati, N. and Karaman, B. and Cabaye, A. and Tora, A. S. and Commare, B. and Courtiol, T. and Cesarini, S. and McCort-Tranchepain, I. and Rigault, D. and Mony, L. and Bessiron, T. and McLean, H. and Leroux, F. R. and Colobert, F. and Daniel, H. and Goupil-Lamy, A. and Bertrand, H. O. and Goudet, C. and Pin, J. P. and Acher, F. C.

Increased Potency and Selectivity for Group III Metabotropic Glutamate Receptor Agonists Binding at Dual sites

J Med Chem (2018)

61, 1969-1989

10.1021/acs.jmedchem.7b01438

Servant, N. and Romejon, J. and Gestraud, P. and La Rosa, P. and Lucotte, G. and Lair, S. and Bernard, V. and Zeitouni, B. and Coffin, F. and Jules-Clement, G. and Yvon, F. and Lermine, A. and Poullet, P. and Liva, S. and Pook, S. and Popova, T. and Barette, C. and Prud'homme, F. and Dick, J. G. and Kamal, M. and Le Tourneau, C. and Barillot, E. and Hupe, P.

Bioinformatics for precision medicine in oncology: principles and application to the SHIVA clinical trial

Front Genet (2014)

5, 152

10.3389/fgene.2014.00152

Sevajol, M. and Subissi, L. and Decroly, E. and Canard, B. and Imbert, I.

Insights into RNA synthesis, capping, and proofreading mechanisms of SARS-coronavirus

Virus Res (2014)

194, 90-9

10.1016/j.virusres.2014.10.008

Sharaf el dein, O. and Gallerne, C. and Brenner, C. and Lemaire, C.

Increased expression of VDAC1 sensitizes carcinoma cells to apoptosis induced by DNA cross-linking agents

Biochem Pharmacol (2012)

83, 1172-82

10.1016/j.bcp.2012.01.017

Sharaf el dein, O. and Mayola, E. and Chopineau, J. and Brenner, C.

The adenine nucleotide translocase 2, a mitochondrial target for anticancer biotherapy

Curr Drug Targets (2011)

12, 894-901

Sharma, H. and Jollivet Souchet, M. and Callebaut, I. and Prasad, R. and Becq, F.

Function, pharmacological correction and maturation of new Indian CFTR gene mutations

J Cyst Fibros (2015)

14, 34-41

10.1016/j.jcf.2014.06.008

Shen, Y. and Maupetit, J. and Derreumaux, P. and Tuffery, P.

Improved PEP-FOLD Approach for Peptide and Miniprotein Structure Prediction

J Chem Theory Comput (2014)

10, 4745-58

10.1021/ct500592m

Shen, Y. and Picord, G. and Guyon, F. and Tuffery, P.

Detecting protein candidate fragments using a structural alphabet profile comparison approach

PLoS One (2013)

8, e80493

10.1371/journal.pone.0080493

Shi, X. and Betzi, S. and Lugari, A. and Opi, S. and Restouin, A. and Parrot, I. and Martinez, J. and Zimmermann, P. and Lecine, P. and Huang, M. and Arold, S. T. and Collette, Y. and Morelli, X.

Structural recognition mechanisms between human Src homology domain 3 (SH3) and ALG-2-interacting protein X (Alix)

FEBS Lett (2012)

586, 1759-64

10.1016/j.febslet.2012.05.017

Shihavuddin, A. and Basu, S. and Rexhepaj, E. and Delestro, F. and Menezes, N. and Sigoillot, S. M. and Del Nery, E. and Selimi, F. and Spassky, N. and Genovesio, A.

Smooth 2D manifold extraction from 3D image stack

Nat Commun (2017)

8, 15554

10.1038/ncomms15554

Shtanko, O. and Sakurai, Y. and Reyes, A. N. and Noel, R. and Cintrat, J. C. and Gillet, D. and Barbier, J. and Davey, R. A.

Retro-2 and its dihydroquinazolinone derivatives inhibit filovirus infection

Antiviral Res (2018)

149, 154-163

10.1016/j.antiviral.2017.11.016

Sidorov, P. and Davioud-Charvet, E. and Marcou, G. and Horvath, D. and Varnek, A.

AntiMalarial Mode of Action (AMMA) Database: Data Selection, Verification and Chemical Space Analysis

Mol Inform (2018)

,

10.1002/minf.201800021

Sidorov, P. and Desta, I. and Chesse, M. and Horvath, D. and Marcou, G. and Varnek, A. and Davioud-Charvet, E. and Elhabiri, M.

Redox Polypharmacology as an Emerging Strategy to Combat Malarial Parasites

ChemMedChem (2016)

11, 1339-51

10.1002/cmdc.201600009

Sidorov, P. and Gaspar, H. and Marcou, G. and Varnek, A. and Horvath, D.

Mappability of drug-like space: towards a polypharmacologically competent map of drug-relevant compounds

J Comput Aided Mol Des (2015)

29, 1087-108

10.1007/s10822-015-9882-z

Sidorov, P. and Viira, B. and Davioud-Charvet, E. and Maran, U. and Marcou, G. and Horvath, D. and Varnek, A.

QSAR modeling and chemical space analysis of antimalarial compounds

J Comput Aided Mol Des (2017)

31, 441-451

10.1007/s10822-017-0019-4

Silva, V. A. and Lafont, F. and Benhelli-Mokrani, H. and Breton, M. L. and Hulin, P. and Chabot, T. and Paris, F. and Sakanyan, V. and Fleury, F.

Rapid Diminution in the Level and Activity of DNA-Dependent Protein Kinase in Cancer Cells by a Reactive Nitro-Benzoxadiazole Compound

Int J Mol Sci (2016)

17,

10.3390/ijms17050703

Silva-Miranda, M. and Ekaza, E. and Breiman, A. and Asehnoune, K. and Barros-Aguirre, D. and Pethe, K. and Ewann, F. and Brodin, P. and Ballell-Pages, L. and Altare, F.

High-content screening technology combined with a human granuloma model as a new approach to evaluate the activities of drugs against Mycobacterium tuberculosis

Antimicrob Agents Chemother (2015)

59, 693-7

10.1128/AAC.03705-14

Simeone, R. and Sayes, F. and Song, O. and Groschel, M. I. and Brodin, P. and Brosch, R. and Majlessi, L.

Cytosolic access of Mycobacterium tuberculosis: critical impact of phagosomal acidification control and demonstration of occurrence in vivo

PLoS Pathog (2015)

11, e1004650

10.1371/journal.ppat.1004650

Singh, V. and Dhar, N. and Pato, J. and Kolly, G. S. and Kordulakova, J. and Forbak, M. and Evans, J. C. and Szekely, R. and Rybniker, J. and Palcekova, Z. and Zemanova, J. and Santi, I. and Signorino-Gelo, F. and Rodrigues, L. and Vocat, A. and Covarrubias, A. S. and Rengifo, M. G. and Johnsson, K. and Mowbray, S. and Buechler, J. and Delorme, V. and Brodin, P. and Knott, G. W. and Ainsa, J. A. and Warner, D. F. and Keri, G. and Mikusova, K. and McKinney, J. D. and Cole, S. T. and Mizrahi, V. and Hartkoorn, R. C.

Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria

Mol Microbiol (2017)

103, 13-25

10.1111/mmi.13535

Sinico, M. and Bassez, G. and Touboul, C. and Cave, H. and Vergnaud, A. and Zirah, C. and Fleury-Feith, J. and Gettler, S. and Vojtek, A. M. and Chevalier, N. and Amram, D. and Alsamad, I. A. and Haddad, B. and Encha-Razavi, F.

Excess of neuromuscular spindles in a fetus with Costello syndrome: a clinicopathological report

Pediatr Dev Pathol (2011)

14, 218-23

10.2350/09-06-0664-CR.1

Sinou, V. and Fiot, J. and Taudon, N. and Mosnier, J. and Martelloni, M. and Bun, S. S. and Parzy, D. and Ollivier, E.

High-performance liquid chromatographic method for the quantification of Mitragyna inermis alkaloids in order to perform pharmacokinetic studies

J Sep Sci (2010)

33, 1863-9

10.1002/jssc.201000008

Sinou, V. and Quang le, H. and Pelleau, S. and Huong, V. N. and Huong, N. T. and Tai le, M. and Bertaux, L. and Desbordes, M. and Latour, C. and Long, L. Q. and Thanh, N. X. and Parzy, D.

Polymorphism of Plasmodium falciparum Na(+)/H(+) exchanger is indicative of a low in vitro quinine susceptibility in isolates from Viet Nam

Malar J (2011)

10, 164

10.1186/1475-2875-10-164

Sitbon, M. and Biard-Piechaczyk, M. and Robert, V. and Briant, L. and Kohler, S. and Labesse, G. and Devaux, C.

Montpellier infectious diseases (MID): 1st annual meeting (2011)

Infect Genet Evol (2011)

11, 1493-8

10.1016/j.meegid.2011.07.001

Slynko, I. and Da Silva, F. and Bret, G. and Rognan, D.

Docking pose selection by interaction pattern graph similarity: application to the D3R grand challenge 2015

J Comput Aided Mol Des (2016)

30, 669-683

10.1007/s10822-016-9930-3

Song, L. and Merceron, R. and Gracia, B. and Quintana, A. L. and Risseeuw, M. D. P. and Hulpia, F. and Cos, P. and Ainsa, J. A. and Munier-Lehmann, H. and Savvides, S. N. and Van Calenbergh, S.

Structure Guided Lead Generation toward Nonchiral M. tuberculosis Thymidylate Kinase Inhibitors

J Med Chem (2018)

61, 2753-2775

10.1021/acs.jmedchem.7b01570

Song, L. and Risseeuw, M. D. P. and Froeyen, M. and Karalic, I. and Goeman, J. and Cappoen, D. and Van der Eycken, J. and Cos, P. and Munier-Lehmann, H. and Van Calenbergh, S.

Elaboration of a proprietary thymidylate kinase inhibitor motif towards anti-tuberculosis agents

Bioorg Med Chem (2016)

24, 5172-5182

10.1016/j.bmc.2016.08.041

Song, L. and Risseeuw, M. D. P. and Froeyen, M. and Karalic, I. and Goeman, J. and Cappoen, D. and Van der Eycken, J. and Cos, P. and Munier-Lehmann, H. and Van Calenbergh, S.

Corrigenda to "Elaboration of a proprietary thymidylate kinase inhibitor motif towards anti-tuberculosis agents" [Bioorg Med Chem 24 (2016) 5172-5182]

Bioorg Med Chem (2017)

25, 5889

10.1016/j.bmc.2017.08.023

Song, O. R. and Deboosere, N. and Delorme, V. and Queval, C. J. and Deloison, G. and Werkmeister, E. and Lafont, F. and Baulard, A. and Iantomasi, R. and Brodin, P.

Phenotypic assays for Mycobacterium tuberculosis infection

Cytometry A (2017)

91, 983-994

10.1002/cyto.a.23129

Song, O. R. and Kim, H. B. and Jouny, S. and Ricard, I. and Vandeputte, A. and Deboosere, N. and Marion, E. and Queval, C. J. and Lesport, P. and Bourinet, E. and Henrion, D. and Oh, S. B. and Lebon, G. and Sandoz, G. and Yeramian, E. and Marsollier, L. and Brodin, P.

A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone

Toxins (Basel) (2017)

9,

10.3390/toxins9070227

Song, O. R. and Marion, E. and Comoglio, Y. and Babonneau, J. and Guerineau, N. and Sandoz, G. and Yeramian, E. and Brodin, P. and Marsollier, L.

[Mycolactone: the amazing analgesic mycobacterial toxin]

Med Sci (Paris) (2016)

32, 156-8

10.1051/medsci/20163202007

Song, O. R. and Queval, C. J. and Iantomasi, R. and Delorme, V. and Marion, S. and Veyron-Churlet, R. and Werkmeister, E. and Popoff, M. and Ricard, I. and Jouny, S. and Deboosere, N. and Lafont, F. and Baulard, A. and Yeramian, E. and Marsollier, L. and Hoffmann, E. and Brodin, P.

ArfGAP1 restricts Mycobacterium tuberculosis entry by controlling the actin cytoskeleton

EMBO Rep (2018)

19, 29-42

10.15252/embr.201744371

Sopkova-de Oliveira Santos, J. and Lesnard, A. and Agondanou, J. H. and Dupont, N. and Godard, A. M. and Stiebing, S. and Rochais, C. and Fabis, F. and Dallemagne, P. and Bureau, R. and Rault, S.

Virtual screening discovery of new acetylcholinesterase inhibitors issued from CERMN chemical library

J Chem Inf Model (2010)

50, 422-8

10.1021/ci900491t

Sorres, J. and Martin, M. T. and Petek, S. and Levaique, H. and Cresteil, T. and Ramos, S. and Thoison, O. and Debitus, C. and Al-Mourabit, A.

Pipestelides A-C: cyclodepsipeptides from the Pacific marine sponge Pipestela candelabra

J Nat Prod (2012)

75, 759-63

10.1021/np200714m

Soussi, M. A. and Provot, O. and Bernadat, G. and Bignon, J. and Desravines, D. and Dubois, J. and Brion, J. D. and Messaoudi, S. and Alami, M.

IsoCombretaQuinazolines: Potent Cytotoxic Agents with Antitubulin Activity

ChemMedChem (2015)

10, 1392-402

10.1002/cmdc.201500069

Sperandio, O. and Reynes, C. H. and Camproux, A. C. and Villoutreix, B. O.

Rationalizing the chemical space of protein-protein interaction inhibitors

Drug Discov Today (2010)

15, 220-9

10.1016/j.drudis.2009.11.007

Sperandio, O. and Villoutreix, B. O. and Morelli, X. and Roche, P.

[Chemical libraries dedicated to protein-protein interactions]

Med Sci (Paris) (2015)

31, 312-9

10.1051/medsci/20153103017

Sperandio, O. and Wildhagen, K. C. and Schrijver, R. and Wielders, S. and Villoutreix, B. O. and Nicolaes, G. A.

Identification of novel small molecule inhibitors of activated protein C

Thromb Res (2014)

133, 1105-14

10.1016/j.thromres.2014.01.026

Starzec, A. and Miteva, M. A. and Ladam, P. and Villoutreix, B. O. and Perret, G. Y.

Discovery of novel inhibitors of vascular endothelial growth factor-A-Neuropilin-1 interaction by structure-based virtual screening

Bioorg Med Chem (2014)

22, 4042-8

10.1016/j.bmc.2014.05.068

Sterpone, F. and Melchionna, S. and Tuffery, P. and Pasquali, S. and Mousseau, N. and Cragnolini, T. and Chebaro, Y. and St-Pierre, J. F. and Kalimeri, M. and Barducci, A. and Laurin, Y. and Tek, A. and Baaden, M. and Nguyen, P. H. and Derreumaux, P.

The OPEP protein model: from single molecules, amyloid formation, crowding and hydrodynamics to DNA/RNA systems

Chem Soc Rev (2014)

43, 4871-93

10.1039/c4cs00048j

Stewart, G. D. and Comps-Agrar, L. and Norskov-Lauritsen, L. B. and Pin, J. P. and Kniazeff, J.

Allosteric interactions between GABAB1 subunits control orthosteric binding sites occupancy within GABAB oligomers

Neuropharmacology (2018)

136, 92-101

10.1016/j.neuropharm.2017.12.042

Stocker, P. and Brunel, J. M. and de Rezende, L. and do Amaral, A. T. and Morelli, X. and Roche, P. and Vidal, N. and Giardina, T. and Perrier, J.

Aminoacylase 1-catalysed deacetylation of bioactives epoxides mycotoxin-derived mercapturates; 3,4-epoxyprecocenes as models of cytotoxic epoxides

Biochimie (2012)

94, 1668-75

10.1016/j.biochi.2012.01.006

Stura, E. A. and Le Roux, L. and Guitot, K. and Garcia, S. and Bregant, S. and Beau, F. and Vera, L. and Collet, G. and Ptchelkine, D. and Bakirci, H. and Dive, V.

Structural framework for covalent inhibition of Clostridium botulinum neurotoxin A by targeting Cys165

J Biol Chem (2012)

287, 33607-14

10.1074/jbc.M112.396697

Sturm, N. and Desaphy, J. and Quinn, R. J. and Rognan, D. and Kellenberger, E.

Structural insights into the molecular basis of the ligand promiscuity

J Chem Inf Model (2012)

52, 2410-21

10.1021/ci300196g

Sturm, N. and Rognan, D. and Quinn, R. J. and Kellenberger, E.

Comparing atom-based with residue-based descriptors in predicting binding site similarity: do backbone atoms matter?

Future Med Chem (2016)

8, 1871-1885

10.4155/fmc-2016-0077

Subissi, L. and Imbert, I. and Ferron, F. and Collet, A. and Coutard, B. and Decroly, E. and Canard, B.

SARS-CoV ORF1b-encoded nonstructural proteins 12-16: replicative enzymes as antiviral targets

Antiviral Res (2014)

101, 122-30

10.1016/j.antiviral.2013.11.006

Subissi, L. and Posthuma, C. C. and Collet, A. and Zevenhoven-Dobbe, J. C. and Gorbalenya, A. E. and Decroly, E. and Snijder, E. J. and Canard, B. and Imbert, I.

One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities

Proc Natl Acad Sci U S A (2014)

111, E3900-9

10.1073/pnas.1323705111

Sun, B. and Chen, L. and Liu, L. and Xia, Z. and Pin, J. P. and Nan, F. and Liu, J.

A negative allosteric modulator modulates GABAB-receptor signalling through GB2 subunits

Biochem J (2016)

473, 779-87

10.1042/BJ20150979

Suthagar, K. and Jiao, W. and Munier-Lehmann, H. and Fairbanks, A. J.

Synthesis of sulfamide analogues of deoxthymidine monophosphate as potential inhibitors of mycobacterial cell wall biosynthesis

Carbohydr Res (2018)

457, 32-40

10.1016/j.carres.2018.01.001

Tabet, R. and Moutin, E. and Becker, J. A. and Heintz, D. and Fouillen, L. and Flatter, E. and Krezel, W. and Alunni, V. and Koebel, P. and Dembele, D. and Tassone, F. and Bardoni, B. and Mandel, J. L. and Vitale, N. and Muller, D. and Le Merrer, J. and Moine, H.

Fragile X Mental Retardation Protein (FMRP) controls diacylglycerol kinase activity in neurons

Proc Natl Acad Sci U S A (2016)

113, E3619-28

10.1073/pnas.1522631113

Tahtouh, T. and Elkins, J. M. and Filippakopoulos, P. and Soundararajan, M. and Burgy, G. and Durieu, E. and Cochet, C. and Schmid, R. S. and Lo, D. C. and Delhommel, F. and Oberholzer, A. E. and Pearl, L. H. and Carreaux, F. and Bazureau, J. P. and Knapp, S. and Meijer, L.

Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B

J Med Chem (2012)

55, 9312-30

10.1021/jm301034u

Tan, X. and Bertonati, C. and Qin, L. and Furio, L. and El Amri, C. and Hovnanian, A. and Reboud-Ravaux, M. and Villoutreix, B. O.

Identification by in silico and in vitro screenings of small organic molecules acting as reversible inhibitors of kallikreins

Eur J Med Chem (2013)

70, 661-8

10.1016/j.ejmech.2013.10.040

Tan, X. and Furio, L. and Reboud-Ravaux, M. and Villoutreix, B. O. and Hovnanian, A. and El Amri, C.

1,2,4-Triazole derivatives as transient inactivators of kallikreins involved in skin diseases

Bioorg Med Chem Lett (2013)

23, 4547-51

10.1016/j.bmcl.2013.06.039

Tarabout, C. and Roux, S. and Gobeaux, F. and Fay, N. and Pouget, E. and Meriadec, C. and Ligeti, M. and Thomas, D. and M, I. Jsselstijn and Besselievre, F. and Buisson, D. A. and Verbavatz, J. M. and Petitjean, M. and Valery, C. and Perrin, L. and Rousseau, B. and Artzner, F. and Paternostre, M. and Cintrat, J. C.

Control of peptide nanotube diameter by chemical modifications of an aromatic residue involved in a single close contact

Proc Natl Acad Sci U S A (2011)

108, 7679-84

10.1073/pnas.1017343108

Techlovska, S. and Chambers, J. N. and Dvorakova, M. and Petralia, R. S. and Wang, Y. X. and Hajkova, A. and Nova, A. and Frankova, D. and Prezeau, L. and Blahos, J.

Metabotropic glutamate receptor 1 splice variants mGluR1a and mGluR1b combine in mGluR1a/b dimers in vivo

Neuropharmacology (2014)

86, 329-336

10.1016/j.neuropharm.2014.08.011

Ten Brink, T. and Aguirre, C. and Exner, T. E. and Krimm, I.

Performance of protein-ligand docking with simulated chemical shift perturbations

J Chem Inf Model (2015)

55, 275-83

10.1021/ci500446s

Terraz, G. and Gueguen, G. and Arno, J. and Fleury, F. and Mouton, L.

Nuclear and cytoplasmic differentiation among Mediterranean populations of Bemisia tabaci: testing the biological relevance of cytotypes

Pest Manag Sci (2014)

70, 1503-13

10.1002/ps.3792

Tesse, A. and Grossini, E. and Tamma, G. and Brenner, C. and Portincasa, P. and Marinelli, R. A. and Calamita, G.

Aquaporins as Targets of Dietary Bioactive Phytocompounds

Front Mol Biosci (2018)

5, 30

10.3389/fmolb.2018.00030

Zussy, C. and Gomez-Santacana, X. and Rovira, X. and De Bundel, D. and Ferrazzo, S. and Bosch, D. and Asede, D. and Malhaire, F. and Acher, F. and Giraldo, J. and Valjent, E. and Ehrlich, I. and Ferraguti, F. and Pin, J. P. and Llebaria, A. and Goudet, C.

Dynamic modulation of inflammatory pain-related affective and sensory symptoms by optical control of amygdala metabotropic glutamate receptor 4

Mol Psychiatry (2018)

23, 509-520

10.1038/mp.2016.223

Zussy, C. and Gomez-Santacana, X. and Rovira, X. and De Bundel, D. and Ferrazzo, S. and Bosch, D. and Asede, D. and Malhaire, F. and Acher, F. and Giraldo, J. and Valjent, E. and Ehrlich, I. and Ferraguti, F. and Pin, J. P. and Llebaria, A. and Goudet, C.

Optical activation of endogenous metabotropic glutamate receptor 4 (mGlu4) in the amygdala dynamically regulates symptoms associated with persistent inflammatory pain

Mol Psychiatry (2018)

23, 489

10.1038/mp.2018.4

Tudor, D. and Yu, H. and Maupetit, J. and Drillet, A. S. and Bouceba, T. and Schwartz-Cornil, I. and Lopalco, L. and Tuffery, P. and Bomsel, M.

Isotype modulates epitope specificity, affinity, and antiviral activities of anti-HIV-1 human broadly neutralizing 2F5 antibody

Proc Natl Acad Sci U S A (2012)

109, 12680-5

10.1073/pnas.1200024109

Tuffery, P.

Accessing external innovation in drug discovery and development

Expert Opin Drug Discov (2015)

10, 579-89

10.1517/17460441.2015.1040759

Tuffery, P. and Derreumaux, P.

Flexibility and binding affinity in protein-ligand, protein-protein and multi-component protein interactions: limitations of current computational approaches

J R Soc Interface (2012)

9, 20-33

10.1098/rsif.2011.0584

Tufo, G. and Jones, A. W. and Wang, Z. and Hamelin, J. and Tajeddine, N. and Esposti, D. D. and Martel, C. and Boursier, C. and Gallerne, C. and Migdal, C. and Lemaire, C. and Szabadkai, G. and Lemoine, A. and Kroemer, G. and Brenner, C.

The protein disulfide isomerases PDIA4 and PDIA6 mediate resistance to cisplatin-induced cell death in lung adenocarcinoma

Cell Death Differ (2014)

21, 685-95

10.1038/cdd.2013.193

Turapov, O. and Waddell, S. J. and Burke, B. and Glenn, S. and Sarybaeva, A. A. and Tudo, G. and Labesse, G. and Young, D. I. and Young, M. and Andrew, P. W. and Butcher, P. D. and Cohen-Gonsaud, M. and Mukamolova, G. V.

Oleoyl coenzyme A regulates interaction of transcriptional regulator RaaS (Rv1219c) with DNA in mycobacteria

J Biol Chem (2014)

289, 25241-9

10.1074/jbc.M114.577338

Turpaev, K. and Ermolenko, M. and Cresteil, T. and Drapier, J. C.

Benzylidenemalononitrile compounds as activators of cell resistance to oxidative stress and modulators of multiple signaling pathways. A structure-activity relationship study

Biochem Pharmacol (2011)

82, 535-47

10.1016/j.bcp.2011.05.028

Ufarte, L. and Bozonnet, S. and Laville, E. and Cecchini, D. A. and Pizzut-Serin, S. and Jacquiod, S. and Demaneche, S. and Simonet, P. and Franqueville, L. and Veronese, G. P.

Functional Metagenomics: Construction and High-Throughput Screening of Fosmid Libraries for Discovery of Novel Carbohydrate-Active Enzymes

Methods Mol Biol (2016)

1399, 257-71

10.1007/978-1-4939-3369-3_15

Ulferts, R. and de Boer, S. M. and van der Linden, L. and Bauer, L. and Lyoo, H. R. and Mate, M. J. and Lichiere, J. and Canard, B. and Lelieveld, D. and Omta, W. and Egan, D. and Coutard, B. and van Kuppeveld, F. J.

Screening of a Library of FDA-Approved Drugs Identifies Several Enterovirus Replication Inhibitors That Target Viral Protein 2C

Antimicrob Agents Chemother (2016)

60, 2627-38

10.1128/AAC.02182-15

Ursuegui, S. and Recher, M. and Krezel, W. and Wagner, A.

An in vivo strategy to counteract post-administration anticoagulant activity of azido-Warfarin

Nat Commun (2017)

8, 15242

10.1038/ncomms15242

Vachel, L. and Norez, C. and Becq, F. and Vandebrouck, C.

Effect of VX-770 (ivacaftor) and OAG on Ca2+ influx and CFTR activity in G551D and F508del-CFTR expressing cells

J Cyst Fibros (2013)

12, 584-91

10.1016/j.jcf.2013.05.008

Vachel, L. and Norez, C. and Jayle, C. and Becq, F. and Vandebrouck, C.

The low PLC-delta1 expression in cystic fibrosis bronchial epithelial cells induces upregulation of TRPV6 channel activity

Cell Calcium (2015)

57, 38-48

10.1016/j.ceca.2014.11.005

Valduga, M. and Philippe, C. and Bach Segura, P. and Thiebaugeorges, O. and Miton, A. and Beri, M. and Bonnet, C. and Nemos, C. and Foliguet, B. and Jonveaux, P.

A retrospective study by oligonucleotide array-CGH analysis in 50 fetuses with multiple malformations

Prenat Diagn (2010)

30, 333-41

10.1002/pd.2460

Valduga, M. and Philippe, C. and Lambert, L. and Bach-Segura, P. and Schmitt, E. and Masutti, J. P. and Francois, B. and Pinaud, P. and Vibert, M. and Jonveaux, P.

WWOX and severe autosomal recessive epileptic encephalopathy: first case in the prenatal period

J Hum Genet (2015)

60, 267-71

10.1038/jhg.2015.17

Valencia, C. and Dujet, C. and Margathe, J. F. and Iturrioz, X. and Roux, T. and Trinquet, E. and Villa, P. and Hibert, M. and Dupuis, E. and Llorens-Cortes, C. and Bonnet, D.

A Time-Resolved FRET Cell-Based Binding Assay for the Apelin Receptor

ChemMedChem (2017)

12, 925-931

10.1002/cmdc.201700106

Valetti, S. and Xia, X. and Costa-Gouveia, J. and Brodin, P. and Bernet-Camard, M. F. and Andersson, M. and Feiler, A.

Clofazimine encapsulation in nanoporous silica particles for the oral treatment of antibiotic-resistant Mycobacterium tuberculosis infections

Nanomedicine (Lond) (2017)

12, 831-844

10.2217/nnm-2016-0364

van der Linden, L. and Vives-Adrian, L. and Selisko, B. and Ferrer-Orta, C. and Liu, X. and Lanke, K. and Ulferts, R. and De Palma, A. M. and Tanchis, F. and Goris, N. and Lefebvre, D. and De Clercq, K. and Leyssen, P. and Lacroix, C. and Purstinger, G. and Coutard, B. and Canard, B. and Boehr, D. D. and Arnold, J. J. and Cameron, C. E. and Verdaguer, N. and Neyts, J. and van Kuppeveld, F. J.

The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family

PLoS Pathog (2015)

11, e1004733

10.1371/journal.ppat.1004733

Vanucci-Bacque, C. and Camare, C. and Carayon, C. and Bernis, C. and Baltas, M. and Negre-Salvayre, A. and Bedos-Belval, F.

Synthesis and evaluation of antioxidant phenolic diaryl hydrazones as potent antiangiogenic agents in atherosclerosis

Bioorg Med Chem (2016)

24, 3571-8

10.1016/j.bmc.2016.05.067

Vanucci-Bacque, C. and Carayon, C. and Bernis, C. and Camare, C. and Negre-Salvayre, A. and Bedos-Belval, F. and Baltas, M.

Synthesis, antioxidant and cytoprotective evaluation of potential antiatherogenic phenolic hydrazones. A structure-activity relationship insight

Bioorg Med Chem (2014)

22, 4269-76

10.1016/j.bmc.2014.05.034

Varnek, A.

Fragment descriptors in structure-property modeling and virtual screening

Methods Mol Biol (2011)

672, 213-43

10.1007/978-1-60761-839-3_9

Varnek, A. and Baskin, II

Chemoinformatics as a Theoretical Chemistry Discipline

Mol Inform (2011)

30, 20-32

10.1002/minf.201000100

Varnek, A. and Baskin, I.

Machine learning methods for property prediction in chemoinformatics: Quo Vadis?

J Chem Inf Model (2012)

52, 1413-37

10.1021/ci200409x

Vaur, P. and Brugg, B. and Mericskay, M. and Li, Z. and Schmidt, M. S. and Vivien, D. and Orset, C. and Jacotot, E. and Brenner, C. and Duplus, E.

Nicotinamide riboside, a form of vitamin B3, protects against excitotoxicity-induced axonal degeneration

FASEB J (2017)

31, 5440-5452

10.1096/fj.201700221RR

Veau, D. and Krykun, S. and Mori, G. and Orena, B. S. and Pasca, M. R. and Frongia, C. and Lobjois, V. and Chassaing, S. and Lherbet, C. and Baltas, M.

Triazolophthalazines: Easily Accessible Compounds with Potent Antitubercular Activity

ChemMedChem (2016)

11, 1078-89

10.1002/cmdc.201600085

Vediyappan, G. and Dumontet, V. and Pelissier, F. and d'Enfert, C.

Gymnemic acids inhibit hyphal growth and virulence in Candida albicans

PLoS One (2013)

8, e74189

10.1371/journal.pone.0074189

Velic, D. and Couturier, A. M. and Ferreira, M. T. and Rodrigue, A. and Poirier, G. G. and Fleury, F. and Masson, J. Y.

DNA Damage Signalling and Repair Inhibitors: The Long-Sought-After Achilles' Heel of Cancer

Biomolecules (2015)

5, 3204-59

10.3390/biom5043204

Veneziano, R. and Rossi, C. and Chenal, A. and Brenner, C. and Ladant, D. and Chopineau, J.

Synthesis and characterization of tethered lipid assemblies for membrane protein reconstitution (Review)

Biointerphases (2017)

12, 04E301

10.1116/1.4994299

Vergalli, J. and Dumont, E. and Pajovic, J. and Cinquin, B. and Maigre, L. and Masi, M. and Refregiers, M. and Pages, J. M.

Spectrofluorimetric quantification of antibiotic drug concentration in bacterial cells for the characterization of translocation across bacterial membranes

Nat Protoc (2018)

13, 1348-1361

10.1038/nprot.2018.036

Viaud, J. and Lagarrigue, F. and Ramel, D. and Allart, S. and Chicanne, G. and Ceccato, L. and Courilleau, D. and Xuereb, J. M. and Pertz, O. and Payrastre, B. and Gaits-Iacovoni, F.

Phosphatidylinositol 5-phosphate regulates invasion through binding and activation of Tiam1

Nat Commun (2014)

5, 4080

10.1038/ncomms5080

Vidal, B. and Karpenko, I. A. and Liger, F. and Fieux, S. and Bouillot, C. and Billard, T. and Hibert, M. and Zimmer, L.

[(11)C]PF-3274167 as a PET radiotracer of oxytocin receptors: Radiosynthesis and evaluation in rat brain

Nucl Med Biol (2017)

55, 1-6

10.1016/j.nucmedbio.2017.07.008

Vidalain, P. O. and Lucas-Hourani, M. and Helynck, O. and Tangy, F. and Munier-Lehmann, H.

[Stimulation of the antiviral innate immune response by pyrimidine biosynthesis inhibitors: a surprise of phenotypic screening]

Med Sci (Paris) (2015)

31, 98-104

10.1051/medsci/20153101019

Viglino, D. and Vesin, A. and Ruckly, S. and Morelli, X. and Slama, R. and Debaty, G. and Danel, V. and Maignan, M. and Timsit, J. F.

Daily volume of cases in emergency call centers: construction and validation of a predictive model

Scand J Trauma Resusc Emerg Med (2017)

25, 86

10.1186/s13049-017-0430-9

Vigneron, S. and Gharbi-Ayachi, A. and Raymond, A. A. and Burgess, A. and Labbe, J. C. and Labesse, G. and Monsarrat, B. and Lorca, T. and Castro, A.

Characterization of the mechanisms controlling Greatwall activity

Mol Cell Biol (2011)

31, 2262-75

10.1128/MCB.00753-10

Vigneron, S. and Gharbi-Ayachi, A. and Raymond, A. A. and Burgess, A. and Labbe, J. C. and Labesse, G. and Monsarrat, B. and Lorca, T. and Castro, A.

Correction for Vigneron et al., "Characterization of the Mechanisms Controlling Greatwall Activity"

Mol Cell Biol (2017)

37,

10.1128/MCB.00231-17

Viira, B. and Gendron, T. and Lanfranchi, D. A. and Cojean, S. and Horvath, D. and Marcou, G. and Varnek, A. and Maes, L. and Maran, U. and Loiseau, P. M. and Davioud-Charvet, E.

In Silico Mining for Antimalarial Structure-Activity Knowledge and Discovery of Novel Antimalarial Curcuminoids

Molecules (2016)

21,

10.3390/molecules21070853

Villemagne, B. and Crauste, C. and Flipo, M. and Baulard, A. R. and Deprez, B. and Willand, N.

Tuberculosis: the drug development pipeline at a glance

Eur J Med Chem (2012)

51, 1-16

10.1016/j.ejmech.2012.02.033

Villemagne, B. and Flipo, M. and Blondiaux, N. and Crauste, C. and Malaquin, S. and Leroux, F. and Piveteau, C. and Villeret, V. and Brodin, P. and Villoutreix, B. O. and Sperandio, O. and Soror, S. H. and Wohlkonig, A. and Wintjens, R. and Deprez, B. and Baulard, A. R. and Willand, N.

Ligand efficiency driven design of new inhibitors of Mycobacterium tuberculosis transcriptional repressor EthR using fragment growing, merging, and linking approaches

J Med Chem (2014)

57, 4876-88

10.1021/jm500422b

Villoutreix, B. O.

Combining bioinformatics, chemoinformatics and experimental approaches to design chemical probes: Applications in the field of blood coagulation

Ann Pharm Fr (2016)

74, 253-66

10.1016/j.pharma.2016.03.006

Villoutreix, B. O. and Khatib, A. M. and Cheng, Y. and Miteva, M. A. and Marechal, X. and Vidal, J. and Reboud-Ravaux, M.

Blockade of the malignant phenotype by beta-subunit selective noncovalent inhibition of immuno- and constitutive proteasomes

Oncotarget (2017)

8, 10437-10449

10.18632/oncotarget.14428

Villoutreix, B. O. and Kuenemann, M. A. and Poyet, J. L. and Bruzzoni-Giovanelli, H. and Labbe, C. and Lagorce, D. and Sperandio, O. and Miteva, M. A.

Drug-Like Protein-Protein Interaction Modulators: Challenges and Opportunities for Drug Discovery and Chemical Biology

Mol Inform (2014)

33, 414-437

10.1002/minf.201400040

Villoutreix, B. O. and Labbe, C. M. and Lagorce, D. and Laconde, G. and Sperandio, O.

A leap into the chemical space of protein-protein interaction inhibitors

Curr Pharm Des (2012)

18, 4648-67

Villoutreix, B. O. and Laconde, G. and Lagorce, D. and Martineau, P. and Miteva, M. A. and Dariavach, P.

Tyrosine kinase syk non-enzymatic inhibitors and potential anti-allergic drug-like compounds discovered by virtual and in vitro screening

PLoS One (2011)

6, e21117

10.1371/journal.pone.0021117

Villoutreix, B. O. and Lagorce, D. and Labbe, C. M. and Sperandio, O. and Miteva, M. A.

One hundred thousand mouse clicks down the road: selected online resources supporting drug discovery collected over a decade

Drug Discov Today (2013)

18, 1081-9

10.1016/j.drudis.2013.06.013

Villoutreix, B. O. and Miteva, M. A.

Discoidin Domains as Emerging Therapeutic Targets

Trends Pharmacol Sci (2016)

37, 641-659

10.1016/j.tips.2016.06.003

Villoutreix, B. O. and Sperandio, O.

In silico studies of blood coagulation proteins: from mosaic proteases to nonenzymatic cofactor inhibitors

Curr Opin Struct Biol (2010)

20, 168-79

10.1016/j.sbi.2009.12.016

Villoutreix, B. O. and Taboureau, O.

Computational investigations of hERG channel blockers: New insights and current predictive models

Adv Drug Deliv Rev (2015)

86, 72-82

10.1016/j.addr.2015.03.003

Vilmont, V. and Filhol, O. and Hesse, A. M. and Coute, Y. and Hue, C. and Remy-Tourneur, L. and Mistou, S. and Cochet, C. and Chiocchia, G.

Modulatory role of the anti-apoptotic protein kinase CK2 in the sub-cellular localization of Fas associated death domain protein (FADD)

Biochim Biophys Acta (2015)

1853, 2885-96

10.1016/j.bbamcr.2015.08.001

Vischer, H. F. and Castro, M. and Pin, J. P.

G Protein-Coupled Receptor Multimers: A Question Still Open Despite the Use of Novel Approaches

Mol Pharmacol (2015)

88, 561-71

10.1124/mol.115.099440

Vogelmann, J. and Le Gall, A. and Dejardin, S. and Allemand, F. and Gamot, A. and Labesse, G. and Cuvier, O. and Negre, N. and Cohen-Gonsaud, M. and Margeat, E. and Nollmann, M.

Chromatin insulator factors involved in long-range DNA interactions and their role in the folding of the Drosophila genome

PLoS Genet (2014)

10, e1004544

10.1371/journal.pgen.1004544

Voisset, C. and Blondel, M.

[Chemobiology at happy hour: yeast as a model for pharmacological screening]

Med Sci (Paris) (2014)

30, 1161-8

10.1051/medsci/20143012020

Voisset, C. and Blondel, M. and Jones, G. W. and Friocourt, G. and Stahl, G. and Chedin, S. and Beringue, V. and Gillet, R.

The double life of the ribosome: When its protein folding activity supports prion propagation

Prion (2017)

11, 89-97

10.1080/19336896.2017.1303587

Voisset, C. and Daskalogianni, C. and Contesse, M. A. and Mazars, A. and Arbach, H. and Le Cann, M. and Soubigou, F. and Apcher, S. and Fahraeus, R. and Blondel, M.

A yeast-based assay identifies drugs that interfere with immune evasion of the Epstein-Barr virus

Dis Model Mech (2014)

7, 435-44

10.1242/dmm.014308

Voisset, C. and Garcia-Rodriguez, N. and Birkmire, A. and Blondel, M. and Wellinger, R. E.

Using yeast to model calcium-related diseases: example of the Hailey-Hailey disease

Biochim Biophys Acta (2014)

1843, 2315-21

10.1016/j.bbamcr.2014.02.011

von Massenhausen, A. and Tonnus, W. and Himmerkus, N. and Parmentier, S. and Saleh, D. and Rodriguez, D. and Ousingsawat, J. and Ang, R. L. and Weinberg, J. M. and Sanz, A. B. and Ortiz, A. and Zierleyn, A. and Becker, J. U. and Baratte, B. and Desban, N. and Bach, S. and Schiessl, I. M. and Nogusa, S. and Balachandran, S. and Anders, H. J. and Ting, A. T. and Bleich, M. and Degterev, A. and Kunzelmann, K. and Bornstein, S. R. and Green, D. R. and Hugo, C. and Linkermann, A.

Phenytoin inhibits necroptosis

Cell Death Dis (2018)

9, 359

10.1038/s41419-018-0394-3

Waiker, D. K. and Karthikeyan, C. and Poongavanam, V. and Kongsted, J. and Lozach, O. and Meijer, L. and Trivedi, P.

Synthesis, biological evaluation and molecular modelling studies of 4-anilinoquinazoline derivatives as protein kinase inhibitors

Bioorg Med Chem (2014)

22, 1909-15

10.1016/j.bmc.2014.01.044

Wang, Z. and Figueiredo-Pereira, C. and Oudot, C. and Vieira, H. L. and Brenner, C.

Mitochondrion: A Common Organelle for Distinct Cell Deaths?

Int Rev Cell Mol Biol (2017)

331, 245-287

10.1016/bs.ircmb.2016.09.010

Wang, Z. and Liu, D. and Varin, A. and Nicolas, V. and Courilleau, D. and Mateo, P. and Caubere, C. and Rouet, P. and Gomez, A. M. and Vandecasteele, G. and Fischmeister, R. and Brenner, C.

A cardiac mitochondrial cAMP signaling pathway regulates calcium accumulation, permeability transition and cell death

Cell Death Dis (2016)

7, e2198

10.1038/cddis.2016.106

Wang, Z. and Nicolas, C. and Fischmeister, R. and Brenner, C.

Enzymatic assays for probing mitochondrial apoptosis

Methods Mol Biol (2015)

1265, 407-14

10.1007/978-1-4939-2288-8_30

Waqas, S. F. H. and Hoang, A. C. and Lin, Y. T. and Ampem, G. and Azegrouz, H. and Balogh, L. and Thuroczy, J. and Chen, J. C. and Gerling, I. C. and Nam, S. and Lim, J. S. and Martinez-Ibanez, J. and Real, J. T. and Paschke, S. and Quillet, R. and Ayachi, S. and Simonin, F. and Schneider, E. M. and Brinkman, J. A. and Lamming, D. W. and Seroogy, C. M. and Roszer, T.

Neuropeptide FF increases M2 activation and self-renewal of adipose tissue macrophages

J Clin Invest (2017)

127, 2842-2854

10.1172/JCI90152

Weill, N. and Valencia, C. and Gioria, S. and Villa, P. and Hibert, M. and Rognan, D.

Identification of Nonpeptide Oxytocin Receptor Ligands by Receptor-Ligand Fingerprint Similarity Search

Mol Inform (2011)

30, 521-6

10.1002/minf.201100026

West, C. and Konjaria, M. L. and Shashviashvili, N. and Lemasson, E. and Bonnet, P. and Kakava, R. and Volonterio, A. and Chankvetadze, B.

Enantioseparation of novel chiral sulfoxides on chlorinated polysaccharide stationary phases in supercritical fluid chromatography

J Chromatogr A (2017)

1499, 174-182

10.1016/j.chroma.2017.03.089

Wilson, J. B. and Manet, E. and Gruffat, H. and Busson, P. and Blondel, M. and Fahraeus, R.

EBNA1: Oncogenic Activity, Immune Evasion and Biochemical Functions Provide Targets for Novel Therapeutic Strategies against Epstein-Barr Virus- Associated Cancers

Cancers (Basel) (2018)

10,

10.3390/cancers10040109

Winfield, H. J. and Cahill, M. M. and O'Shea, K. D. and Pierce, L. T. and Robert, T. and Ruchaud, S. and Bach, S. and Marchand, P. and McCarthy, F. O.

Synthesis and anticancer activity of novel bisindolylhydroxymaleimide derivatives with potent GSK-3 kinase inhibition

Bioorg Med Chem (2018)

26, 4209-4224

10.1016/j.bmc.2018.07.012

Wu, Q. and Allouch, A. and Martins, I. and Brenner, C. and Modjtahedi, N. and Deutsch, E. and Perfettini, J. L.

Modulating Both Tumor Cell Death and Innate Immunity Is Essential for Improving Radiation Therapy Effectiveness

Front Immunol (2017)

8, 613

10.3389/fimmu.2017.00613

Wu, Y. and Pons, V. and Goudet, A. and Panigai, L. and Fischer, A. and Herweg, J. A. and Kali, S. and Davey, R. A. and Laporte, J. and Bouclier, C. and Yousfi, R. and Aubenque, C. and Merer, G. and Gobbo, E. and Lopez, R. and Gillet, C. and Cojean, S. and Popoff, M. R. and Clayette, P. and Le Grand, R. and Boulogne, C. and Tordo, N. and Lemichez, E. and Loiseau, P. M. and Rudel, T. and Sauvaire, D. and Cintrat, J. C. and Gillet, D. and Barbier, J.

ABMA, a small molecule that inhibits intracellular toxins and pathogens by interfering with late endosomal compartments

Sci Rep (2017)

7, 15567

10.1038/s41598-017-15466-7

Xue, L. and Rovira, X. and Scholler, P. and Zhao, H. and Liu, J. and Pin, J. P. and Rondard, P.

Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer

Nat Chem Biol (2015)

11, 134-40

10.1038/nchembio.1711

Yahiaoui, S. and Hamidouche, K. and Ballandonne, C. and Davis, A. and de Oliveira Santos, J. S. and Freret, T. and Boulouard, M. and Rochais, C. and Dallemagne, P.

Design, synthesis, and pharmacological evaluation of multitarget-directed ligands with both serotonergic subtype 4 receptor (5-HT4R) partial agonist and 5-HT6R antagonist activities, as potential treatment of Alzheimer's disease

Eur J Med Chem (2016)

121, 283-293

10.1016/j.ejmech.2016.05.048

Yang, B. and Ming, X. and Abdelkafi, H. and Pons, V. and Michau, A. and Gillet, D. and Cintrat, J. C. and Barbier, J. and Juliano, R.

Retro-1 Analogues Differentially Affect Oligonucleotide Delivery and Toxin Trafficking

ChemMedChem (2016)

11, 2506-2510

10.1002/cmdc.201600463

Yang, Y. and Labesse, G. and Carrere-Kremer, S. and Esteves, K. and Kremer, L. and Cohen-Gonsaud, M. and Blanc-Potard, A. B.

The C-terminal domain of the virulence factor MgtC is a divergent ACT domain

J Bacteriol (2012)

194, 6255-63

10.1128/JB.01424-12

Yefimova, M. G. and Bere, E. and Cantereau-Becq, A. and Harnois, T. and Meunier, A. C. and Messaddeq, N. and Becq, F. and Trottier, Y. and Bourmeyster, N.

Myelinosomes act as natural secretory organelles in Sertoli cells to prevent accumulation of aggregate-prone mutant Huntingtin and CFTR

Hum Mol Genet (2016)

25, 4170-4185

10.1093/hmg/ddw251

Yekwa, E. and Khourieh, J. and Canard, B. and Papageorgiou, N. and Ferron, F.

Activity inhibition and crystal polymorphism induced by active-site metal swapping

Acta Crystallogr D Struct Biol (2017)

73, 641-649

10.1107/S205979831700866X

Yu, J. and Picord, G. and Tuffery, P. and Guerois, R.

HHalign-Kbest: exploring sub-optimal alignments for remote homology comparative modeling

Bioinformatics (2015)

31, 3850-2

10.1093/bioinformatics/btv441

Yu, J. and Vavrusa, M. and Andreani, J. and Rey, J. and Tuffery, P. and Guerois, R.

InterEvDock: a docking server to predict the structure of protein-protein interactions using evolutionary information

Nucleic Acids Res (2016)

44, W542-9

10.1093/nar/gkw340