ChemBioFrance - Votre Projet

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Including ...

- Select all the necessary steps for your project in the table below. Depending on the boxes ticked, you will then be asked to specify your request.
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Cheminformatics
                                Molecular databases
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                                                Access to molecular databases
                                            
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                                Virtual screening
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                                                Virtual screening of compound libraries
                                            
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                                                Characterization and optimization of interfering peptides.
                                            
                                        help
                                    
                                                Design and Analysis of Focused Libraries (eg : protein-Protein Interaction Inhibitors)
                                            
                                        help
                                    
                                Modelling and prediction of biological activity
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                                                QSAR modelling of biological activity
                                            
                                        help
                                    
                                                Searching for unwanted chemical motifs
                                            
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                                                Target identification and profiling
                                            
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                                QSAR and ligands optimization
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                                                Predicting physicochemical and biological properties by QSAR
                                            
                                        help
                                    
                                                Visualization and Analysis of Chemical Data
                                            
                                        help
                                    
                                                Fragment Optimization (hit-to-lead)
                                            
                                        help
                                    
                                                Prediction of the residence time (RT) of compounds
                                            
                                        help
                                    
Screening
                                Screening
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                                                Scratch Wound Healing assay
                                            
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                                                Molecular screening on purified targets ("Target-based")
                                            
                                        help
                                    
                                                Phenotypic screening on cells or living organisms ("Phenotypic-based")
                                            
                                        help
                                    
                                                Measuring the effect of ligands on cells (label-free)
                                            
                                        help
                                    
                                                Measurement of second messengers (cAMP, IP1, calcium...)
                                            
                                        help
                                    
                                                Measurement of excreted proteins (chemokines, cytokines, etc.)
                                            
                                        help
                                    
                                                Measurement of molecular interactions using Epic Label Free technology
                                            
                                        help
                                    
                                                Assay miniaturization
                                            
                                        help
                                    
                                                Viral, bacterial replication
                                            
                                        help
                                    
                                                Evaluation of the cytotoxic effects of a compound
                                            
                                        help
                                    
                                                Protein kinase assays (Characterization of Protein kinase Inhibitors)
                                            
                                        help
                                    
Adme-tox
                                ADME
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                                                Physico-chemical characterization
                                            
                                        help
                                    
                                                In vitro assays (absorption, metabolism)
                                            
                                        help
                                    
                                                In vivo tests (distribution, elimination)
                                            
                                        help
                                    
                                                Toxicity
                                            
                                        help
                                    
                                                Mouse pharmacokinetics
                                            
                                        help
                                    
                                                Metabolic stability - liver S9 fraction
                                            
                                        help
                                    
                                                Metabolic stability - liver microsomes
                                            
                                        help
                                    
                                                Plasma stability
                                            
                                        help
                                    
                                                Lipophilicity: log D (shake flask)
                                            
                                        help
                                    
                                                Permeability - (Parallel Artificial Membrane Permeability Assay)
                                            
                                        help
                                    
                                                pKa
                                            
                                        help
                                    
                                                Kinetic solubility
                                            
                                        help
                                    
                                                Thermodynamic solubility
                                            
                                        help
                                    
                                                Chemical stability
                                            
                                        help
                                    
                                                Plasma protein binding
                                            
                                        help
                                    
Chemical Library
                                Compounds
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                                                French Chemical Library (CN - complete collection)
                                            
                                        help
                                    
                                                Essential Chemical Library (CNE)
                                            
                                        help
                                    
                                                Custom collections (cherry-picking)
                                            
                                        help
                                    
                                                Targeted libraries
                                            
                                        help
                                    
                                                Dose-response plates
                                            
                                        help
                                    
                                                Fr-PPIChem : A Chemical Library to Target Protein-Protein Interactions
                                            
                                        help
                                    
                                Extracts
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                                                Extract library (global library)
                                            
                                        help
                                    
                                                extract families
                                            
                                        help

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Your project request

1.
You wish ...

2.
Including ...

Cheminformatics

Molecular databases

Virtual screening

Modelling and prediction of biological activity

QSAR and ligands optimization

Screening

Screening

Adme-tox

ADME

Chemical Library

Compounds

Extracts

3.
Precize your request ...

3
Precize your request ...

${form.name}

4.
Submit ...

Your project request

${infoPrestationTitle}

1. You wish ...

2. Including ...

Cheminformatics

Molecular databases keyboard_arrow_left

Virtual screening keyboard_arrow_left

Modelling and prediction of biological activity keyboard_arrow_left

QSAR and ligands optimization keyboard_arrow_left

Screening

Screening keyboard_arrow_left

Adme-tox

ADME keyboard_arrow_left

Chemical Library

Compounds keyboard_arrow_left

Extracts keyboard_arrow_left

3. Precize your request ...

3 Precize your request ...

${form.name}

4. Submit ...

1.
You wish ...

2.
Including ...

Molecular databases

Virtual screening

Modelling and prediction of biological activity

QSAR and ligands optimization

Screening

ADME

Compounds

Extracts

3.
Precize your request ...

3
Precize your request ...

4.
Submit ...