Postdoctoral position in organic chemistry/medicinal chemistry
General informations
Lieu : CEA-Saclay, Department of bioorganic chemistry and isotopic labeling, Gif sur Yvette
Type de contrat :
postdoctoral fellow
Quotité de travail :
100
Employeur :
CEA
Rémunération : 2100-2300€ net per month
Date d'embauche prévue :
2021-10-01
Durée du contrat :
12 months
Missions/Activités :
In the frame of a collaborative project aiming at discovering compounds that interfere with the
intracellular retrograde trafficking, our group is developing small molecules that have been shown by
us and other groups to have a broad "therapeutic" activity (look for Retro-2 references) .
Based on the experience we acquired on Retro-2 analogs (see for instance J. Med. Chem. 2013, 56, 8,
3404-3413) and based on in silico design we now aim at developing a completely new chemical series
for which we already have encouraging preliminary results.
The postdoctoral fellow will be hosted at the SCBM (Service de Chimie Bioorganique et de
Marquage/Université Paris-Saclay) at CEA-Saclay under the supervision of Dr Jean-Christophe Cintrat
and will work in close collaboration with biology team within the network. All experiments will be
dealing with heterocyclic chemistry and may require some basic knowledge of in silico drug design.
Compétences
Niveau d'études souhaité :
PhD in organic chemistry
Compétences souhaitées :
the successful candidate is a skilled organic/medicinal chemist, holder of a PhD in organic chemistry, with a strong scientific record and a high motivation. Good verbal and written communication skills and a flair for teamwork are required. A previous (i
Divers
Autres informations :
applicants should send their CV with a list of current publications, a cover letter
motivating their interest in the position and the names and addresses of two referees to jeanchristophe.
cintrat@cea.fr. The selected candidate is expected to start in October/November 2021.
Applications are considered from now, until the position is filled.
Contact
Lastname : Dr Cintrat
Email : jean-christophe.cintrat@cea.fr